EP2843039A4 - Neuartiger stamm zur herstellung von d-milchsäure und verwendung davon - Google Patents

Neuartiger stamm zur herstellung von d-milchsäure und verwendung davon

Info

Publication number
EP2843039A4
EP2843039A4 EP13780610.5A EP13780610A EP2843039A4 EP 2843039 A4 EP2843039 A4 EP 2843039A4 EP 13780610 A EP13780610 A EP 13780610A EP 2843039 A4 EP2843039 A4 EP 2843039A4
Authority
EP
European Patent Office
Prior art keywords
lactic acid
strain producing
novel strain
novel
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP13780610.5A
Other languages
English (en)
French (fr)
Other versions
EP2843039B1 (de
EP2843039A1 (de
Inventor
Eun Bin Yang
Tae Hee Lee
Seon Hye Kim
Young Lyeol Yang
Hong Xian Li
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CJ CheilJedang Corp
Original Assignee
CJ CheilJedang Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CJ CheilJedang Corp filed Critical CJ CheilJedang Corp
Priority to PL13780610T priority Critical patent/PL2843039T3/pl
Publication of EP2843039A1 publication Critical patent/EP2843039A1/de
Publication of EP2843039A4 publication Critical patent/EP2843039A4/de
Application granted granted Critical
Publication of EP2843039B1 publication Critical patent/EP2843039B1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56—Lactic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01027—L-Lactate dehydrogenase (1.1.1.27)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01028—D-Lactate dehydrogenase (1.1.1.28)
EP13780610.5A 2012-04-24 2013-04-24 Neuartiger stamm zur herstellung von d-milchsäure und verwendung davon Active EP2843039B1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL13780610T PL2843039T3 (pl) 2012-04-24 2013-04-24 Nowy szczep produkujący kwas D-mlekowy i jego zastosowanie

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20120042894A KR101438882B1 (ko) 2012-04-24 2012-04-24 신규한 ｄ형 젖산 생산균주
PCT/KR2013/003501 WO2013162274A1 (ko) 2012-04-24 2013-04-24 신규한 ｄ형 젖산 생산균주 및 그의 용도

Publications (3)

Publication Number Publication Date
EP2843039A1 EP2843039A1 (de) 2015-03-04
EP2843039A4 true EP2843039A4 (de) 2016-01-06
EP2843039B1 EP2843039B1 (de) 2020-11-04

Family

ID=49483496

Family Applications (1)

Application Number Title Priority Date Filing Date
EP13780610.5A Active EP2843039B1 (de) 2012-04-24 2013-04-24 Neuartiger stamm zur herstellung von d-milchsäure und verwendung davon

Country Status (13)

Country Link
US (1) US10138500B2 (de)
EP (1) EP2843039B1 (de)
JP (2) JP6085023B2 (de)
KR (1) KR101438882B1 (de)
CN (1) CN104395456A (de)
AU (1) AU2013253153B2 (de)
BR (1) BR112014026720B1 (de)
MY (1) MY182333A (de)
PL (1) PL2843039T3 (de)
RU (1) RU2639507C2 (de)
SG (2) SG11201406876VA (de)
UA (1) UA116444C2 (de)
WO (1) WO2013162274A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101438882B1 (ko) 2012-04-24 2014-09-05 씨제이제일제당 (주) 신규한 ｄ형 젖산 생산균주
KR102144997B1 (ko) * 2014-02-14 2020-08-14 삼성전자주식회사 락테이트 데히드로게나제 변이체, 상기 변이체를 코딩하는 폴리뉴클레오티드, 상기 폴리뉴클레오티드를 포함하는 효모 세포, 상기 변이체의 제조 방법 및 이를 이용한 락테이트의 생산 방법
KR102214835B1 (ko) * 2014-09-19 2021-02-10 삼성전자주식회사 락테이트 데히드로게나제 변이체, 상기 변이체를 코딩하는 폴리뉴클레오티드, 상기 폴리뉴클레오티드를 포함하는 효모 세포, 및 이를 이용한 락테이트의 생산 방법
KR101577134B1 (ko) * 2014-05-09 2015-12-14 씨제이제일제당 (주) 젖산 생산이 향상된 미생물 및 이를 이용하여 젖산을 생산하는 방법
JP6637026B2 (ja) * 2014-07-23 2020-01-29 ピュラック バイオケム ビー． ブイ． 遺伝子改変された（ｒ）−乳酸産生好熱性細菌
KR101719035B1 (ko) * 2014-09-19 2017-03-23 포항공과대학교 산학협력단 신규 효소를 사용한 d형 젖산의 제조
KR102581464B1 (ko) * 2015-05-28 2023-09-21 삼성전자주식회사 락테이트 데히드로게나제 변이체를 스크리닝하는 방법, 락테이트 데히드로게나제 변이체, 상기 변이체를 포함하는 폴리뉴클레오티드, 벡터, 미생물, 및 상기 미생물을 이용하여 락테이트를 생산하는 방법
CN107922917A (zh) * 2015-06-12 2018-04-17 Cj第制糖株式会社 乳酸生产率提高的微生物和使用其生产乳酸的方法
MY182357A (en) * 2015-10-16 2021-01-20 Iner Aec Executive Yuan Highly optically pure l-lactic acid-producing strain with tolerance to lignocellulosic hydrolysate
CN107267476B (zh) * 2016-04-08 2019-08-30 中国科学院微生物研究所 一种乳酸脱氢酶及其在制备乳酸中应用
CN109385389A (zh) * 2017-08-08 2019-02-26 光明乳业股份有限公司 一种缺失ldhA基因的植物乳杆菌ST-Ⅲ及其制备方法
KR101915463B1 (ko) 2018-05-02 2018-11-06 (주)잇츠한불 신규한 락토바실러스 펜토서스 균주 및 이를 포함하는 프로바이오틱스 제제 또는 조성물
CN109504630B (zh) * 2018-12-17 2022-03-11 吉林中粮生化有限公司 一种重组d-乳酸生产植物乳杆菌菌株及利用该菌株生产d-乳酸的方法
JP2021007309A (ja) * 2019-06-28 2021-01-28 裕希 土肥 形質転換体およびそれを用いたｄ−乳酸の生産方法
CN111500517B (zh) * 2020-05-27 2020-12-11 吉林中粮生化有限公司 产l-乳酸的重组菌株及其构建方法和发酵产l-乳酸的方法及应用
CN111378698B (zh) * 2020-06-01 2020-12-25 中粮营养健康研究院有限公司 发酵制备d-乳酸的方法
CN111849852A (zh) * 2020-06-01 2020-10-30 华东理工大学 一种高光学纯l-乳酸工程菌的构建方法

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JP2931939B2 (ja) 1992-07-10 1999-08-09 明治乳業株式会社 Ｌａｃｔｏｂａｃｉｌｌｕｓ ｄｅｌｂｒｕｅｃｋｉｉ 種染色体への遺伝子組込み方法及び遺伝子組込み体
PH31093A (en) * 1993-08-06 1998-02-05 Nestec Ltd Lactobacillus bulgaricus having decreased acid production and/or improved aroma and flavor production and food composition comprising said lactobacillus.
DK0875579T3 (da) * 1997-05-03 2007-10-22 Nestle Sa Fremstilling af L(+)-laktat
AU2003251381B2 (en) 2002-05-30 2008-04-03 Natureworks Llc Fermentation process using specific oxygen uptake rates as a process control
CN1245515C (zh) * 2004-03-03 2006-03-15 南开大学 L－乳酸脱氢酶基因、包括该基因的重组载体及其宿主细胞
US20060025190A1 (en) 2004-07-28 2006-02-02 Kraft David W System and method of gaming involving continued distribution of components until certain criteria are met
DE102007047206B4 (de) * 2007-10-02 2016-08-11 Insilico Biotechnology Ag Biotechnologische Fixierung von Kohlenstoffdioxid
CN101993850B (zh) * 2010-08-08 2012-11-14 天津大学 一种生产d-乳酸基因工程菌及构建方法和应用
KR101438882B1 (ko) 2012-04-24 2014-09-05 씨제이제일제당 (주) 신규한 ｄ형 젖산 생산균주

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
K. OKANO ET AL: "Homo-D-Lactic Acid Fermentation from Arabinose by Redirection of the Phosphoketolase Pathway to the Pentose Phosphate Pathway in L-Lactate Dehydrogenase Gene-Deficient Lactobacillus plantarum", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 75, no. 15, 5 June 2009 (2009-06-05), pages 5175 - 5178, XP055172716, ISSN: 0099-2240, DOI: 10.1128/AEM.00573-09 *
See also references of WO2013162274A1 *
SHOHEI OKINO ET AL: "Production of d-lactic acid by Corynebacterium glutamicum under oxygen deprivation", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, SPRINGER, BERLIN, DE, vol. 78, no. 3, 10 January 2008 (2008-01-10), pages 449 - 454, XP019586313, ISSN: 1432-0614 *

Also Published As

Publication number Publication date
UA116444C2 (uk) 2018-03-26
JP6085023B2 (ja) 2017-02-22
KR20130126809A (ko) 2013-11-21
PL2843039T3 (pl) 2021-07-05
RU2014144647A (ru) 2016-06-10
BR112014026720A2 (pt) 2017-06-27
EP2843039B1 (de) 2020-11-04
JP2015514434A (ja) 2015-05-21
SG11201406876VA (en) 2015-01-29
MY182333A (en) 2021-01-19
KR101438882B1 (ko) 2014-09-05
BR112014026720B1 (pt) 2023-02-23
AU2013253153A1 (en) 2014-11-20
US20150118724A1 (en) 2015-04-30
EP2843039A1 (de) 2015-03-04
SG10201803888UA (en) 2018-06-28
WO2013162274A1 (ko) 2013-10-31
JP2017070288A (ja) 2017-04-13
CN104395456A (zh) 2015-03-04
US10138500B2 (en) 2018-11-27
RU2639507C2 (ru) 2017-12-21
AU2013253153B2 (en) 2017-06-08

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