EP1539583A1 - Verfahren und vorrichtung zur herstellung einer prim ren ein zelverpackung eines wafers - Google Patents
Verfahren und vorrichtung zur herstellung einer prim ren ein zelverpackung eines wafersInfo
- Publication number
- EP1539583A1 EP1539583A1 EP03757797A EP03757797A EP1539583A1 EP 1539583 A1 EP1539583 A1 EP 1539583A1 EP 03757797 A EP03757797 A EP 03757797A EP 03757797 A EP03757797 A EP 03757797A EP 1539583 A1 EP1539583 A1 EP 1539583A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- packaging material
- active substance
- wafer
- film
- material webs
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B9/00—Enclosing successive articles, or quantities of material, e.g. liquids or semiliquids, in flat, folded, or tubular webs of flexible sheet material; Subdividing filled flexible tubes to form packages
- B65B9/02—Enclosing successive articles, or quantities of material between opposed webs
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B61/00—Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages
Definitions
- the invention relates to a method and a device for producing a primary individual packaging of a wafer, in particular a wafer removed from an active substance film of one or more active substances for use as a dosage unit and dosage form for pharmaceuticals.
- the dosage form of the “Wafer TM” is a thin plate made of an active substance film with a predetermined quantity of active substance, the thickness and dimensions of which are closely matched to the active substance to be dispensed.
- a wafer is flexible, soft, light in weight and tearable. Since the contact area of the wafer is directly related to the dosing quantity of the active substance, its dimensions must largely correspond to the calculated ones and be within the tolerance range. Due to the dependence of the dosage on the surface, the soft active substance film material must not be stretched before cutting, since otherwise the amount of active substance would be changed. Therefore, the production of the wafer and its individual packaging or the packaging of several wafers in a primary packaging unit are also complex.
- DE 198 00 682 A1 discloses a method for producing a primary packaging unit for film-like or wafer-like dosage forms (wafers) for oral application, each with a section of a top and bottom web of packaging material.
- the method which can basically also be applied to individual packaging of wafers, has a different procedure for square or rectangular wafers versus making wafers with a different shape.
- a first step an upper and a lower web are brought together over a deflecting shaft without cold or hot deformation, with the film or wafer-like dosage form being guided between the two packaging materials with the aid of rollers or tongs.
- an active substance film can also be supplied as a web product - single-lane or multi-lane parallel at a distance from one another - with the desired width of the dose units.
- Dose units from the web-like active substance film are then separated by a cross-cutting device which is positioned directly in front of the deflecting shafts.
- the two packaging material webs are sealed against one another with the aid of a heated sealing tool in such a way that the individual dose units are sealed in compartments and are completely surrounded by sealing seams or sealing surfaces.
- perforations are punched between the compartments and primary packaging units are divided off.
- the process for producing the primary packaging unit according to DE 198 00 682 AI is designed as follows: In a first process step, a laminate of the sheet-like active substance film and a carrier film is made available, from which another Step with a punching device, the dose units are punched out without punching out the carrier film. The punched laminate is then deflected with the aid of roller or pliers advantages over an edge or deflecting shaft in such a way that the dose units detach from the carrier film. If necessary, a scraper can also be used.
- a packaging material top and bottom web without cold or Hot forming is guided one above the other via a deflecting shaft, the dose units detaching from the carrier film being guided between the two packaging material webs at the same time.
- the two packaging material webs are then sealed against one another with the aid of a heated sealing tool in such a way that the individual dose units are sealed in compartments and are completely surrounded by sealing seams or sealing surfaces.
- perforations are punched between the compartments and primary packaging units are divided off. It goes without saying that this method can also be used for the production and primary individual packaging of square or rectangular wafers.
- devices for carrying out the respective method have also become known.
- One of these devices has a storage device for a laminate of an active substance film and a carrier film, a cutting or punching device for the active substance film for punching a wafer on the carrier film, a separating tool for detaching the active substance film from the carrier film, a preferred device for the carrier film and thus also the active substance film with the wafer, a packaging material feed and preferred device for two plastic webs which take over the respective wafer, a heated sealing tool for the plastic and a cutting tool for separating the sealing bag.
- the wafer material is elastic and can change its shape and dimensions as a result of the mechanical stress during the transport movement between the packaging material upper and lower webs, with the risk that the amount of active substance in the individual wafer also changes, since the area of the wafer is decisive for the dosage of the active ingredient is.
- the required constancy of the amount of active substance cannot be ensured because the wafer material is mechanically stressed before it is inserted between the packaging material webs.
- the method according to the invention consists in that a laminate of a carrier film and an active substance film is provided and pulled off, the carrier film being detached from the active substance film and wound up separately.
- the active substance film is also moved forward by the preferred movement of the carrier film. With its front end, it is guided between two stationary packaging material webs without mechanical stress, fixed by these and cross-cut to produce the wafer at a predetermined rearward distance from these. Subsequently, the wafer fixed between the packaging material webs is advanced together and synchronously with the latter, the preferential force acting on the packaging material webs, and fed to a sealing station. In this sealing station, the packaging material webs are sealed outside the arrangement area of the wafer to form a bag, which is then separated from the packaging material webs.
- the laminate is produced in the coating process and then cut into strips, which are wound up, the width of a coil corresponding to the width of the desired wafer or a multiple of this wafer width. If several wafers are cut out of the coil, the individual wafers are spread and brought to the width that is necessary to insert them into the packaging material webs.
- the spool is provided as a supply spool.
- the separated wafer is then held in place during the preferred movement of the packaging material webs over its entire extent and is not mechanically stressed in the process.
- the packaging material webs are sealed into a bag, there is no risk of damage to the wafer fixed between them. The procedure is easy to do.
- the active substance film detached from the carrier film is guided in a vertical orientation between the packaging material webs which are at a standstill and arranged at a distance from one another in this method step. Then they are placed on the wafer and pulled forward at the same speed and in the same preferred direction on both sides of the active substance film, so that the active substance film is pulled mechanically unloaded between the packaging material webs.
- the packaging material webs are guided through a clamping device which engages the packaging material webs at the end of the working cycle in which the front end of the active substance film was placed between the packaging material webs presses and fixes the wafer. A relative movement between this and the packaging material webs is excluded. In this position, the active substance film is cut at a predetermined distance from the clamping station to separate a wafer, and in the next work step is drawn between the packaging material webs completely and without stress and pulled forward.
- the device for carrying out the method has, in a known manner, a storage device for the laminate formed from a carrier film and an active substance film, a separating tool for detaching the active substance film from the carrier film, a preferred device for this and thus also the active substance film, a cutting tool for the latter, a packaging material feed - and preferential arrangement for two
- Packing material webs which also come from a packaging material roll and can be separated and deflected by means of a separation process, have a heated sealing tool for the packaging material and a cutting tool for separating the finished sealed edge bag.
- the packaging material feed and feed device is provided with a receiving and clamping device for the front end of the active substance film, which is arranged in the vertical direction under the separating tool for detaching the active substance and the cutting tool for it, such that the Active substance film detached from the carrier film reaches the receiving and clamping device in a vertical direction downwards during a feed stroke.
- the drug film is not mechanically loaded.
- the receiving and clamping device is preferably formed from clamping rollers, between which the packaging material webs are tensioned and which act in opposite directions to one another between a receiving position for the active substance film and a clamping position for the latter in the horizontal direction and thus transversely to the preferred direction of the active substance film. are movable. Two pairs of pinch rollers can be arranged one above the other to form an inlet funnel for the active substance film.
- Fig.1 a device for producing a primary individual packaging of a wafer
- the device shown in FIG. 1 has on the input side a supply reel 1 with a preferred laminate 4 consisting of a carrier film 2 and an active substance film 3, a deflection roller 5 and a stripper 6 for detaching the active substance film 3 from the carrier film 2 and a spool 8 for winding the carrier film 2.
- a cross cutting device 10 with a knife (not shown further) and a packaging material feed and preference device 11 for two packaging material tracks 12 are arranged on the cutting device side has a receiving and clamping device formed from two pairs of clamping rollers 13 and 14 arranged one above the other.
- the packaging material webs 12 are arranged on supply rolls 15 and are guided via the clamping rolls 13 and 14 to preferred rolls 16, by means of which they are fixed in a clamping manner and are advanced, whereby they also bear tightly against the clamping rolls 13 and 14. Heated transverse sealing and longitudinal sealing tools 17 and 18 are arranged between these (13, 14) and the preferred rollers 16 and a flat knife 19 as a transverse cutting tool in the preferred direction after the preferred rollers 16.
- laminate 4 with the predetermined width of the wafer in the predetermined length thereof is drawn off from the supply spool 1 by actuating the spool 8.
- the active substance film 3 is detached from the carrier film 2 by the separating roller 7 and aligned vertically downward through the guide tracks or strips 9, these having no clamping function in relation to the active substance film 3.
- the front end of the active substance film 3 passes between the clamping rollers 13 and 14, which are at a distance from one another in their receiving position, via which the packaging material webs 12 are guided on the active substance film side and bear tightly against them in the receiving position.
- the packaging material webs 12 are provided with a transverse sealing seam 20 which now represents the front or bottom seam of the sealed edge bag to be produced or the primary individual packaging of the wafer. This process step is shown in FIG. 2. In the next process step (FIG.
- the packaging material webs 12 are pressed by the clamping rollers 13, 14 onto the front area of the drawn-out active substance film 3 and this is fixed between the packaging material webs 12 by moving them (13, 14) towards one another.
- a wafer 21 in the predetermined length is now separated from the active substance film 3 by the cross-cutting device 10.
- the packaging material webs 12 with the wafer clamped between them are advanced by a synchronous actuation of the preferred rollers 16 to the position of the rear transverse sealing seam (FIG. 4), the wafer 21 being moved smoothly and at the same speed as the packaging material webs 12. In this position, the packaging material webs 12 are on the two long sides by the two
- the resulting transverse sealing seam is chosen so wide that it can be cross-divided and both the back Sealed seam of the primary individual packaging that has just been manufactured, but still has to be separated, as well as the shape or bottom seam of the subsequent individual packaging.
- the pinch rollers 13, 14 are brought into their receiving position and thus opened. This method step is shown in FIG.
- the next cycle begins again with the introduction of the active substance film between the pinch rollers 13 and 14 located in the receiving position, as described above. After each cycle, a primary individual package 22 of a wafer 21 produced in this way is separated from the subsequent individual package by the flat knife 19.
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Containers And Plastic Fillers For Packaging (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Dicing (AREA)
- Auxiliary Devices For And Details Of Packaging Control (AREA)
- Making Paper Articles (AREA)
Description
Claims
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SI200330645T SI1539583T1 (sl) | 2002-09-16 | 2003-09-06 | Postopek in naprava za izdelavo posamezne primarne embalaze vafra |
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41126902P | 2002-09-16 | 2002-09-16 | |
US411269P | 2002-09-16 | ||
DE10249705 | 2002-10-25 | ||
DE10249705A DE10249705A1 (de) | 2002-09-16 | 2002-10-25 | Verfahren und Vorrichtung zur Herstellung einer primären Einzelverpackung eines Wafers |
PCT/EP2003/009911 WO2004026692A1 (de) | 2002-09-16 | 2003-09-06 | Verfahren und vorrichtung zur herstellung einer primären einzelverpackung eines wafers |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1539583A1 true EP1539583A1 (de) | 2005-06-15 |
EP1539583B1 EP1539583B1 (de) | 2006-11-02 |
Family
ID=32031493
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP03757797A Expired - Lifetime EP1539583B1 (de) | 2002-09-16 | 2003-09-06 | Verfahren und vorrichtung zur herstellung einer primären einzelverpackung eines wafers |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP1539583B1 (de) |
JP (1) | JP4180054B2 (de) |
KR (1) | KR100958774B1 (de) |
CN (1) | CN100482538C (de) |
AT (1) | ATE344181T1 (de) |
AU (1) | AU2003273833B2 (de) |
BR (1) | BR0314407B1 (de) |
CA (1) | CA2495122C (de) |
DE (1) | DE50305600D1 (de) |
DK (1) | DK1539583T3 (de) |
ES (1) | ES2276107T3 (de) |
MX (1) | MXPA05002595A (de) |
NO (1) | NO331288B1 (de) |
PL (1) | PL204113B1 (de) |
RU (1) | RU2290355C2 (de) |
WO (1) | WO2004026692A1 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4972729B2 (ja) * | 2006-04-24 | 2012-07-11 | パウダーテック株式会社 | シュート、シート供給装置、およびシート包装機 |
CN102514765B (zh) * | 2012-01-09 | 2014-02-26 | 山东碧海机械有限公司 | 一种无菌纸盒灌装机的密封条不间断送条装置 |
CN107651230A (zh) * | 2016-07-25 | 2018-02-02 | 杨辰 | 医用采血管打包装置 |
DE102017006991B4 (de) | 2017-07-26 | 2020-02-27 | Lts Lohmann Therapie-Systeme Ag | Vorrichtung und Verfahren zur Herstellung von Siegelrandbeuteln |
CN108163244B (zh) * | 2018-01-19 | 2023-07-25 | 珠海市安粤科技有限公司 | 一种工业胶片自动包装装置 |
CN114955028A (zh) * | 2022-05-16 | 2022-08-30 | 厦门高容纳米新材料科技有限公司 | 一种粉体自动包装系统及方法 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1876961U (de) * | 1963-03-02 | 1963-08-01 | Noack E Th Verpackungsmasch | Verpackungsmaschine fuer heftpflaster. |
DE1895537U (de) * | 1963-08-27 | 1964-06-25 | Noack E Th Verpackungsmasch | Maschine zum verpacken von flachem, bandfoermigem material. |
IT712838A (de) * | 1963-12-05 | |||
JPS5153964Y2 (de) * | 1972-08-21 | 1976-12-23 | ||
JPS50150590A (de) * | 1974-05-28 | 1975-12-03 | ||
JPS6145304U (ja) * | 1984-08-29 | 1986-03-26 | ナショナル住宅産業株式会社 | シ−ト梱包機 |
US4841712A (en) * | 1987-12-17 | 1989-06-27 | Package Service Company, Inc. | Method of producing sealed protective pouchs with premium object enclosed therein |
US5182128A (en) * | 1991-03-12 | 1993-01-26 | Kraft General Foods Canada Inc. | Method and apparatus for producing a wrapped food material in single slice form |
US5643391A (en) * | 1995-01-13 | 1997-07-01 | Hunt Holdings, Inc. | Method and apparatus for an improved roller system for calendar machines |
CA2177113A1 (en) * | 1995-05-23 | 1996-11-24 | Takayuki Yamaguchi | Method and apparatus of producing sheet wrapping body |
JPH0939930A (ja) * | 1995-07-26 | 1997-02-10 | Morita & Co:Kk | マーキング方法 |
DE19800682B4 (de) * | 1998-01-10 | 2004-07-08 | Lts Lohmann Therapie-Systeme Ag | Verfahren zur Herstellung einer Primärverpackung für film- oder oblatenförmige Darreichungsformen |
-
2003
- 2003-09-06 BR BRPI0314407-0A patent/BR0314407B1/pt not_active IP Right Cessation
- 2003-09-06 DK DK03757797T patent/DK1539583T3/da active
- 2003-09-06 CA CA2495122A patent/CA2495122C/en not_active Expired - Fee Related
- 2003-09-06 WO PCT/EP2003/009911 patent/WO2004026692A1/de active IP Right Grant
- 2003-09-06 AT AT03757797T patent/ATE344181T1/de active
- 2003-09-06 KR KR1020057004242A patent/KR100958774B1/ko not_active IP Right Cessation
- 2003-09-06 ES ES03757797T patent/ES2276107T3/es not_active Expired - Lifetime
- 2003-09-06 PL PL375880A patent/PL204113B1/pl not_active IP Right Cessation
- 2003-09-06 DE DE50305600T patent/DE50305600D1/de not_active Expired - Lifetime
- 2003-09-06 JP JP2004536996A patent/JP4180054B2/ja not_active Expired - Fee Related
- 2003-09-06 CN CNB038217473A patent/CN100482538C/zh not_active Expired - Fee Related
- 2003-09-06 RU RU2005103607/11A patent/RU2290355C2/ru not_active IP Right Cessation
- 2003-09-06 AU AU2003273833A patent/AU2003273833B2/en not_active Ceased
- 2003-09-06 EP EP03757797A patent/EP1539583B1/de not_active Expired - Lifetime
- 2003-09-06 MX MXPA05002595A patent/MXPA05002595A/es active IP Right Grant
-
2005
- 2005-03-10 NO NO20051250A patent/NO331288B1/no not_active IP Right Cessation
Non-Patent Citations (1)
Title |
---|
See references of WO2004026692A1 * |
Also Published As
Publication number | Publication date |
---|---|
CN1681708A (zh) | 2005-10-12 |
AU2003273833B2 (en) | 2009-11-12 |
KR100958774B1 (ko) | 2010-05-18 |
NO20051250L (no) | 2005-03-10 |
RU2290355C2 (ru) | 2006-12-27 |
NO331288B1 (no) | 2011-11-14 |
BR0314407B1 (pt) | 2012-10-16 |
PL375880A1 (en) | 2005-12-12 |
JP2005538906A (ja) | 2005-12-22 |
ATE344181T1 (de) | 2006-11-15 |
CA2495122C (en) | 2010-06-08 |
ES2276107T3 (es) | 2007-06-16 |
DK1539583T3 (da) | 2007-02-19 |
BR0314407A (pt) | 2005-07-19 |
DE50305600D1 (de) | 2006-12-14 |
MXPA05002595A (es) | 2005-05-27 |
WO2004026692A1 (de) | 2004-04-01 |
EP1539583B1 (de) | 2006-11-02 |
JP4180054B2 (ja) | 2008-11-12 |
AU2003273833A1 (en) | 2004-04-08 |
KR20050065542A (ko) | 2005-06-29 |
CN100482538C (zh) | 2009-04-29 |
PL204113B1 (pl) | 2009-12-31 |
CA2495122A1 (en) | 2004-04-01 |
RU2005103607A (ru) | 2005-07-20 |
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