EP1539583A1 - Method and device for producing a primary individual packing of a wafer - Google Patents

Method and device for producing a primary individual packing of a wafer

Info

Publication number
EP1539583A1
EP1539583A1 EP03757797A EP03757797A EP1539583A1 EP 1539583 A1 EP1539583 A1 EP 1539583A1 EP 03757797 A EP03757797 A EP 03757797A EP 03757797 A EP03757797 A EP 03757797A EP 1539583 A1 EP1539583 A1 EP 1539583A1
Authority
EP
European Patent Office
Prior art keywords
packaging material
active substance
wafer
film
material webs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP03757797A
Other languages
German (de)
French (fr)
Other versions
EP1539583B1 (en
Inventor
Wolfgang Schäfer
Ronald Hackbarth
Hans-Dieter Sahm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LTS Lohmann Therapie Systeme AG
Original Assignee
LTS Lohmann Therapie Systeme AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10249705A external-priority patent/DE10249705A1/en
Application filed by LTS Lohmann Therapie Systeme AG filed Critical LTS Lohmann Therapie Systeme AG
Priority to SI200330645T priority Critical patent/SI1539583T1/en
Publication of EP1539583A1 publication Critical patent/EP1539583A1/en
Application granted granted Critical
Publication of EP1539583B1 publication Critical patent/EP1539583B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B9/00—Enclosing successive articles, or quantities of material, e.g. liquids or semiliquids, in flat, folded, or tubular webs of flexible sheet material; Subdividing filled flexible tubes to form packages
    • B65B9/02—Enclosing successive articles, or quantities of material between opposed webs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B61/00—Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages

Definitions

  • the invention relates to a method and a device for producing a primary individual packaging of a wafer, in particular a wafer removed from an active substance film of one or more active substances for use as a dosage unit and dosage form for pharmaceuticals.
  • the dosage form of the “Wafer TM” is a thin plate made of an active substance film with a predetermined quantity of active substance, the thickness and dimensions of which are closely matched to the active substance to be dispensed.
  • a wafer is flexible, soft, light in weight and tearable. Since the contact area of the wafer is directly related to the dosing quantity of the active substance, its dimensions must largely correspond to the calculated ones and be within the tolerance range. Due to the dependence of the dosage on the surface, the soft active substance film material must not be stretched before cutting, since otherwise the amount of active substance would be changed. Therefore, the production of the wafer and its individual packaging or the packaging of several wafers in a primary packaging unit are also complex.
  • DE 198 00 682 A1 discloses a method for producing a primary packaging unit for film-like or wafer-like dosage forms (wafers) for oral application, each with a section of a top and bottom web of packaging material.
  • the method which can basically also be applied to individual packaging of wafers, has a different procedure for square or rectangular wafers versus making wafers with a different shape.
  • a first step an upper and a lower web are brought together over a deflecting shaft without cold or hot deformation, with the film or wafer-like dosage form being guided between the two packaging materials with the aid of rollers or tongs.
  • an active substance film can also be supplied as a web product - single-lane or multi-lane parallel at a distance from one another - with the desired width of the dose units.
  • Dose units from the web-like active substance film are then separated by a cross-cutting device which is positioned directly in front of the deflecting shafts.
  • the two packaging material webs are sealed against one another with the aid of a heated sealing tool in such a way that the individual dose units are sealed in compartments and are completely surrounded by sealing seams or sealing surfaces.
  • perforations are punched between the compartments and primary packaging units are divided off.
  • the process for producing the primary packaging unit according to DE 198 00 682 AI is designed as follows: In a first process step, a laminate of the sheet-like active substance film and a carrier film is made available, from which another Step with a punching device, the dose units are punched out without punching out the carrier film. The punched laminate is then deflected with the aid of roller or pliers advantages over an edge or deflecting shaft in such a way that the dose units detach from the carrier film. If necessary, a scraper can also be used.
  • a packaging material top and bottom web without cold or Hot forming is guided one above the other via a deflecting shaft, the dose units detaching from the carrier film being guided between the two packaging material webs at the same time.
  • the two packaging material webs are then sealed against one another with the aid of a heated sealing tool in such a way that the individual dose units are sealed in compartments and are completely surrounded by sealing seams or sealing surfaces.
  • perforations are punched between the compartments and primary packaging units are divided off. It goes without saying that this method can also be used for the production and primary individual packaging of square or rectangular wafers.
  • devices for carrying out the respective method have also become known.
  • One of these devices has a storage device for a laminate of an active substance film and a carrier film, a cutting or punching device for the active substance film for punching a wafer on the carrier film, a separating tool for detaching the active substance film from the carrier film, a preferred device for the carrier film and thus also the active substance film with the wafer, a packaging material feed and preferred device for two plastic webs which take over the respective wafer, a heated sealing tool for the plastic and a cutting tool for separating the sealing bag.
  • the wafer material is elastic and can change its shape and dimensions as a result of the mechanical stress during the transport movement between the packaging material upper and lower webs, with the risk that the amount of active substance in the individual wafer also changes, since the area of the wafer is decisive for the dosage of the active ingredient is.
  • the required constancy of the amount of active substance cannot be ensured because the wafer material is mechanically stressed before it is inserted between the packaging material webs.
  • the method according to the invention consists in that a laminate of a carrier film and an active substance film is provided and pulled off, the carrier film being detached from the active substance film and wound up separately.
  • the active substance film is also moved forward by the preferred movement of the carrier film. With its front end, it is guided between two stationary packaging material webs without mechanical stress, fixed by these and cross-cut to produce the wafer at a predetermined rearward distance from these. Subsequently, the wafer fixed between the packaging material webs is advanced together and synchronously with the latter, the preferential force acting on the packaging material webs, and fed to a sealing station. In this sealing station, the packaging material webs are sealed outside the arrangement area of the wafer to form a bag, which is then separated from the packaging material webs.
  • the laminate is produced in the coating process and then cut into strips, which are wound up, the width of a coil corresponding to the width of the desired wafer or a multiple of this wafer width. If several wafers are cut out of the coil, the individual wafers are spread and brought to the width that is necessary to insert them into the packaging material webs.
  • the spool is provided as a supply spool.
  • the separated wafer is then held in place during the preferred movement of the packaging material webs over its entire extent and is not mechanically stressed in the process.
  • the packaging material webs are sealed into a bag, there is no risk of damage to the wafer fixed between them. The procedure is easy to do.
  • the active substance film detached from the carrier film is guided in a vertical orientation between the packaging material webs which are at a standstill and arranged at a distance from one another in this method step. Then they are placed on the wafer and pulled forward at the same speed and in the same preferred direction on both sides of the active substance film, so that the active substance film is pulled mechanically unloaded between the packaging material webs.
  • the packaging material webs are guided through a clamping device which engages the packaging material webs at the end of the working cycle in which the front end of the active substance film was placed between the packaging material webs presses and fixes the wafer. A relative movement between this and the packaging material webs is excluded. In this position, the active substance film is cut at a predetermined distance from the clamping station to separate a wafer, and in the next work step is drawn between the packaging material webs completely and without stress and pulled forward.
  • the device for carrying out the method has, in a known manner, a storage device for the laminate formed from a carrier film and an active substance film, a separating tool for detaching the active substance film from the carrier film, a preferred device for this and thus also the active substance film, a cutting tool for the latter, a packaging material feed - and preferential arrangement for two
  • Packing material webs which also come from a packaging material roll and can be separated and deflected by means of a separation process, have a heated sealing tool for the packaging material and a cutting tool for separating the finished sealed edge bag.
  • the packaging material feed and feed device is provided with a receiving and clamping device for the front end of the active substance film, which is arranged in the vertical direction under the separating tool for detaching the active substance and the cutting tool for it, such that the Active substance film detached from the carrier film reaches the receiving and clamping device in a vertical direction downwards during a feed stroke.
  • the drug film is not mechanically loaded.
  • the receiving and clamping device is preferably formed from clamping rollers, between which the packaging material webs are tensioned and which act in opposite directions to one another between a receiving position for the active substance film and a clamping position for the latter in the horizontal direction and thus transversely to the preferred direction of the active substance film. are movable. Two pairs of pinch rollers can be arranged one above the other to form an inlet funnel for the active substance film.
  • Fig.1 a device for producing a primary individual packaging of a wafer
  • the device shown in FIG. 1 has on the input side a supply reel 1 with a preferred laminate 4 consisting of a carrier film 2 and an active substance film 3, a deflection roller 5 and a stripper 6 for detaching the active substance film 3 from the carrier film 2 and a spool 8 for winding the carrier film 2.
  • a cross cutting device 10 with a knife (not shown further) and a packaging material feed and preference device 11 for two packaging material tracks 12 are arranged on the cutting device side has a receiving and clamping device formed from two pairs of clamping rollers 13 and 14 arranged one above the other.
  • the packaging material webs 12 are arranged on supply rolls 15 and are guided via the clamping rolls 13 and 14 to preferred rolls 16, by means of which they are fixed in a clamping manner and are advanced, whereby they also bear tightly against the clamping rolls 13 and 14. Heated transverse sealing and longitudinal sealing tools 17 and 18 are arranged between these (13, 14) and the preferred rollers 16 and a flat knife 19 as a transverse cutting tool in the preferred direction after the preferred rollers 16.
  • laminate 4 with the predetermined width of the wafer in the predetermined length thereof is drawn off from the supply spool 1 by actuating the spool 8.
  • the active substance film 3 is detached from the carrier film 2 by the separating roller 7 and aligned vertically downward through the guide tracks or strips 9, these having no clamping function in relation to the active substance film 3.
  • the front end of the active substance film 3 passes between the clamping rollers 13 and 14, which are at a distance from one another in their receiving position, via which the packaging material webs 12 are guided on the active substance film side and bear tightly against them in the receiving position.
  • the packaging material webs 12 are provided with a transverse sealing seam 20 which now represents the front or bottom seam of the sealed edge bag to be produced or the primary individual packaging of the wafer. This process step is shown in FIG. 2. In the next process step (FIG.
  • the packaging material webs 12 are pressed by the clamping rollers 13, 14 onto the front area of the drawn-out active substance film 3 and this is fixed between the packaging material webs 12 by moving them (13, 14) towards one another.
  • a wafer 21 in the predetermined length is now separated from the active substance film 3 by the cross-cutting device 10.
  • the packaging material webs 12 with the wafer clamped between them are advanced by a synchronous actuation of the preferred rollers 16 to the position of the rear transverse sealing seam (FIG. 4), the wafer 21 being moved smoothly and at the same speed as the packaging material webs 12. In this position, the packaging material webs 12 are on the two long sides by the two
  • the resulting transverse sealing seam is chosen so wide that it can be cross-divided and both the back Sealed seam of the primary individual packaging that has just been manufactured, but still has to be separated, as well as the shape or bottom seam of the subsequent individual packaging.
  • the pinch rollers 13, 14 are brought into their receiving position and thus opened. This method step is shown in FIG.
  • the next cycle begins again with the introduction of the active substance film between the pinch rollers 13 and 14 located in the receiving position, as described above. After each cycle, a primary individual package 22 of a wafer 21 produced in this way is separated from the subsequent individual package by the flat knife 19.

Abstract

The invention relates to a method and device for producing a primary individual packing of a wafer according to which a laminate consisting of a carrier foil and of an active substance film is cross-cut with a predetermined length and detached from the carrier foil, is guided between two packaging material webs and, together with these webs, is fed to a sealing station. The packaging webs are sealed to form a packet, after which this packet is detached from the packaging material webs. The invention solves the task of providing a method and device which ensure that the wafer material is not subjected to mechanical stress. The inventive method provides that the carrier foil (2) detached from the active substance film (3) is pulled forward to the predetermined length of the wafer (21), and the active substance film (3) detached therefrom is simultaneously guided with its front end between the stationary packaging material webs (12) without being subjected to mechanical stress, is held and fixed by these packaging material webs, and is cross-cut with the predetermined length at a distance from the webs to form a wafer (21). Afterwards, the wafer (21) is pulled forward together with the packaging substance webs (12) in a synchronous manner and is fed to the sealing station (17/18). To this end, the device is provided with a packaging material feeding and pulling device (11) having a holding and clamping device (13/14), which is provided for holding and clamping the front end of the active substance film (3) and which, in a vertical direction, is mounted underneath the separating roll (7) and the cross-cutting tool (10).

Description

Verfahren und Vorrichtung zur Herstellung einer primären Einzelverpackung eines Wafers Method and device for producing a primary individual packaging of a wafer
Die Erfindung betrifft ein Verfahren und eine Vorrichtung zur Herstellung einer primären Einzelverpackung eines Wafers, insbesondere eines aus einem Wirkstofffilm eines oder mehrerer Wirkstoffe entnommenen Wafers zur Verwendung als Dosiereinheit- und Darreichungsform für Arzneimittel.The invention relates to a method and a device for producing a primary individual packaging of a wafer, in particular a wafer removed from an active substance film of one or more active substances for use as a dosage unit and dosage form for pharmaceuticals.
Neben den bekannten Dosierformen für Arzneimittel, wie Tabletten, Kapseln, Tropfen oder ähnlichen Darreichungs- formen, gibt es auch die Darreichungsform des „Wafer™. Es handelt sich bei diesem um ein dünnes Plättchen aus einem Wirkstofffilm mit einer vorbestimmten Wirkstoffmenge, das in seiner Dicke und seinen Abmessungen auf die abzugebende Wirkstoff enge abgestimmt ist. Ein Wafer ist flexibel, weich, von geringem Gewicht und reißfähig. Da die Kontakt- fläche des Wafers im direkten Zusammenhang mit der Dosier- menge des Wirkstoffs steht, müssen seine Abmessungen weitestgehend mit den errechneten übereinstimmen und im Toleranzbereich liegen. Wegen der Abhängigkeit der Dosierung von der Fläche darf das weiche Wirkstofffilm- material vor dem Schneiden nicht gedehnt werden, da sonst die Wirkstoffmenge verändert werden würde. Daher sind die Herstellung des Wafers und dessen EinzelVerpackung oder die Verpackung mehrerer Wafer in eine Primärverpackungseinheit auch aufwendig.In addition to the well-known dosage forms for medicines, such as tablets, capsules, drops or similar dosage forms, there is also the dosage form of the “Wafer ™”. This is a thin plate made of an active substance film with a predetermined quantity of active substance, the thickness and dimensions of which are closely matched to the active substance to be dispensed. A wafer is flexible, soft, light in weight and tearable. Since the contact area of the wafer is directly related to the dosing quantity of the active substance, its dimensions must largely correspond to the calculated ones and be within the tolerance range. Due to the dependence of the dosage on the surface, the soft active substance film material must not be stretched before cutting, since otherwise the amount of active substance would be changed. Therefore, the production of the wafer and its individual packaging or the packaging of several wafers in a primary packaging unit are also complex.
Aus der DE 198 00 682 AI ist ein Verfahren zur Herstellung einer Primärverpackungseinheit für film- oder oblatenartige Darreichungsformen (Wafer) zur oralen Applikation mit je einem Abschnitt einer Packstoffober- und -unterbahn bekannt. Das grundsätzlich auch auf Einzelverpackungen von Wafern anwendbare Verfahren hat für quadratische oder rechteckige Wafer einen unterschiedlichen Verfahrensablauf gegenüber der Herstellung von Wafern mit einer anderen Gestalt. Für quadratische oder rechteckige Wafer werden in einem ersten Schritt eine Packstoffoberbahn und eine - unterbahn ohne Kalt- oder Heißverformung über jeweils eine Umlenkwelle aufeinandergeführt, wobei gleichzeitig die film- oder oblatenartige Darreichungsform mit Hilfe von Rollen oder Zangenvorzügen zwischen die beiden Packstoffbahnen geführt wird. Dabei kann auch ein Wirkstofffilm als Bahnware - einbahnig oder mehrbahnig parallel im Abstand zueinander - mit der gewünschten Breite der Dosiseinheiten zugeführt werden. Anschließend werden Dosiseinheiten aus dem bahnförmigen Wirkstofffilm durch eine Querschneidevorrichtung vereinzelt, welche unmittelbar vor den Umlenkwellen positioniert ist. In einem weiteren Verfahrens- schritt werden die beiden Packstoffbahnen mit Hilfe eines beheizten Siegelwerkzeuges derart gegeneinander gesiegelt, daß die vereinzelten Dosiseinheiten in Kompartimenten eingesiegelt werden und vollständig von Siegelnähten bzw. Siegelflächen umgeben sind. In weiteren Verfahrensschritten werden Perforationen zwischen den Kompartimenten eingestanzt und Primärverpaσkungseinheiten abgeteilt.DE 198 00 682 A1 discloses a method for producing a primary packaging unit for film-like or wafer-like dosage forms (wafers) for oral application, each with a section of a top and bottom web of packaging material. The method, which can basically also be applied to individual packaging of wafers, has a different procedure for square or rectangular wafers versus making wafers with a different shape. For square or rectangular wafers, in a first step, an upper and a lower web are brought together over a deflecting shaft without cold or hot deformation, with the film or wafer-like dosage form being guided between the two packaging materials with the aid of rollers or tongs. In this case, an active substance film can also be supplied as a web product - single-lane or multi-lane parallel at a distance from one another - with the desired width of the dose units. Dose units from the web-like active substance film are then separated by a cross-cutting device which is positioned directly in front of the deflecting shafts. In a further process step, the two packaging material webs are sealed against one another with the aid of a heated sealing tool in such a way that the individual dose units are sealed in compartments and are completely surrounded by sealing seams or sealing surfaces. In further process steps, perforations are punched between the compartments and primary packaging units are divided off.
Für gewünschte Wafer mit einer anderen als quadratischen oder rechteckigen Gestalt ist das Verfahren zur Herstellung der Primärverpackungseinheit nach der DE 198 00 682 AI wie folgt gestaltet: In einem ersten Verfahrensschritt wird ein Laminat aus dem bahnförmigen Wirkstofffilm und einer Trägerfolie bereitgestellt, aus dem in einem weiteren Schritt mit einer Stanzvorrichtung die Dosiseinheiten aus- gestanzt werden, ohne daß die Trägerfolie durchgestanzt wird. Das angestanzte Laminat wird anschließend mit Hilfe von Rollen- oder Zangenvorzügen über eine Kante oder Umlenkwelle so umgelenkt, daß sich dabei die Dosiseinheiten von der Trägerfolie lösen. Bedarfsweise kann dazu zusätz- lieh auch ein Abstreifer verwendet werden. Danach werden eine Packstoffoberbahn und eine -unterbahn ohne Kalt- oder Heißverformung über jeweils eine Umlenkwelle aufeinander- geführt, wobei gleichzeitig die sich von der Trägerfolie ablösenden Dosiseinheiten zwischen die beiden Packstoffbahnen geführt werden. Anschließend werden die beiden Packstoffbahnen mit Hilfe eines beheizten Siegelwerkzeuges derart gegeneinander gesiegelt, daß die vereinzelten Dosiseinheiten in Kompartimenten eingesiegelt werden und vollständig von Siegelnähten bzw. Siegelflächen umgeben sind. In weiteren Verfahrensschritten werden Perforationen zwischen den Kompartimenten eingestanzt und Primärver- packungseinheiten abgeteilt. Es versteht sich von selbst, daß dieses Verfahren auch zur Herstellung und primären Einzelverpackung von quadratischen oder rechteckförmigen Wafern verwendet werden kann.For desired wafers with a shape other than square or rectangular, the process for producing the primary packaging unit according to DE 198 00 682 AI is designed as follows: In a first process step, a laminate of the sheet-like active substance film and a carrier film is made available, from which another Step with a punching device, the dose units are punched out without punching out the carrier film. The punched laminate is then deflected with the aid of roller or pliers advantages over an edge or deflecting shaft in such a way that the dose units detach from the carrier film. If necessary, a scraper can also be used. Then a packaging material top and bottom web without cold or Hot forming is guided one above the other via a deflecting shaft, the dose units detaching from the carrier film being guided between the two packaging material webs at the same time. The two packaging material webs are then sealed against one another with the aid of a heated sealing tool in such a way that the individual dose units are sealed in compartments and are completely surrounded by sealing seams or sealing surfaces. In further process steps, perforations are punched between the compartments and primary packaging units are divided off. It goes without saying that this method can also be used for the production and primary individual packaging of square or rectangular wafers.
Aus der genannten DE 198 00 682 AI sind auch Vorrichtungen zur Durchführung des jeweiligen Verfahrens bekanntgeworden. Eine dieser Vorrichtungen weist eine Vorratseinrichtung für ein Laminat aus einem Wirkstofffilm und einer Trägerfolie, eine Schneid- bzw. Stanzeinrichtung für den Wirkstofffilm zum Stanzen eines Wafers auf der Trägerfolie, ein Trennwerkzeug zum Ablösen des Wirkstofffilms von der Trägerfolie, eine Vorzugseinrichtung für die Trägerfolie und damit auch den Wirkstofffilm mit dem Wafer, eine Pack- stoffzuführ- und -vorzugseinrichtung für zwei Paσkstoff- bahnen, die den jeweiligen Wafer übernehmen, ein beheiztes Siegelwerkzeug für den Paσkstoff und ein Schneidwerkzeug zum Abtrennen des Siegelbeutels auf.From DE 198 00 682 AI mentioned, devices for carrying out the respective method have also become known. One of these devices has a storage device for a laminate of an active substance film and a carrier film, a cutting or punching device for the active substance film for punching a wafer on the carrier film, a separating tool for detaching the active substance film from the carrier film, a preferred device for the carrier film and thus also the active substance film with the wafer, a packaging material feed and preferred device for two plastic webs which take over the respective wafer, a heated sealing tool for the plastic and a cutting tool for separating the sealing bag.
Das Wafermaterial ist elastisch und kann infolge der mechanischen Beanspruchung bei der Transportbewegung zwischen die Packstoffoberbahn und die -unterbahn seine Form und seine Abmessungen verändern, wobei die Gefahr besteht, daß sich auch die Wirkstoffmenge im vereinzelten Wafer ändert, da ja die Fläche des Wafers maßgebend für die Dosierung des Wirkstoffs ist. Mit den vorbeschriebenen Ver- fahren kann die geforderte Konstanz der Wirkstoffmenge nicht sichergestellt werden, da das Wafermaterial vor dem Einführen zwischen die Packstoffbahnen jeweils"mechanisch beansprucht wird.The wafer material is elastic and can change its shape and dimensions as a result of the mechanical stress during the transport movement between the packaging material upper and lower webs, with the risk that the amount of active substance in the individual wafer also changes, since the area of the wafer is decisive for the dosage of the active ingredient is. With the above described The required constancy of the amount of active substance cannot be ensured because the wafer material is mechanically stressed before it is inserted between the packaging material webs.
Es ist Aufgabe der Erfindung, ein Verfahren Und eine Vorrichtung zur Herstellung einer primären Einzelverpaσkung eines Wafer nach dem Oberbegriff des Anspruchs 1 und des Anspruchs 6 so zu gestalten, daß das Wafermaterial mechanisch unbelastet bleibt .It is an object of the invention to design a method and an apparatus for producing a primary individual package of a wafer according to the preamble of claim 1 and claim 6 in such a way that the wafer material remains mechanically unloaded.
Diese Aufgabe wird bei einem Verfahren nach dem Oberbegriff des Anspruchs 1 und einer Vorrichtung nach dem Oberbegriff des Anspruchs 6 jeweils durch deren kennzeichnende Merkmale gelöst. Vorteilhafte Ausgestaltungen sind in den jeweiligen Unteransprüchen aufgeführt .This object is achieved in a method according to the preamble of claim 1 and a device according to the preamble of claim 6 by their characterizing features. Advantageous refinements are listed in the respective subclaims.
Die erfindungsgemäße Verfahren besteht darin, daß ein Laminat aus einer Trägerfolie und einem Wirkstofffilm bereitgestellt und abgezogen wird, wobei die Tragerfolie vom Wirkstofffilm gelöst und separat aufgewickelt wird. Durch die Vorzugsbewegung der Trägerfolie wird auch der Wirkstofffilm vorwärtsbewegt. Mit seinem vorderen Ende wird dieser mechanisch belastungsfrei zwischen zwei ruhende Packstoffbahnen geführt, von diesen fixiert und zur Herstellung des Wafers im vorbestimmten rückwärtigen Abstand von diesen quergeschnitten. Anschließend wird der zwischen den Packstoffbahnen fixierte Wafer gemeinsam und synchron mit diesen vorgezogen, wobei die Vorzugskraft an den Pack- Stoffbahnen angreift, und einer Siegelstation zuge ührt. In dieser Siegelstation werden die Packstoffbahnen außerhalb des Anordnungsbereiσhes des Wafers zu einem Beutel gesiegelt, der im Anschluß daran von den Packstoffbahnen abgetrennt wird. In bekannter Weise wird das Laminat im Coatingverfahren hergestellt und anschließend zu Streifen geschnitten, die aufgespult werden, wobei die Breite einer Spule der Breite des gewünschten Wafers oder eines Vielfachen dieser Wafer- breite entspricht. Werden mehrere Wafer aus der Spule geschnitten, werden die einzelnen Wafer gespreizt und auf die Breite gebracht, die notwendig ist, um sie in die Packstoffbahnen einzufügen. Die Spule wird als Vorratsspule bereitgestellt. Der besondere Vorteil des Verfahrens liegt darin, daß der Wafer ohne mechanische Beanspruchung transportiert und geführt wird. Das Verfahren wird dabei so durchgeführt, daß die jeweilige Vorzugslänge der Trägerfolie und damit auch des Wirkstofffilms der gewünschten Länge eines Wafers entspricht, so daß die Wafer äußerst präzise reproduzierbar und stets gleich sind. Damit hat jeder Wafer auch die gleiche Wirkstoffdosis. Der vereinzelte Wafer wird danach während der Vorzugsbewegung der Packstoffbahnen über seine gesamte Ausdehung zwischen diesen festgehalten und dabei mechanisch nicht belastet. Beim Siegeln der Packstoffbahnen zu einem Beutel besteht keine Gefahr einer Beschädigung des zwischen diesen fixierten Wafers. Das Verfahren ist einfach durchzuführen.The method according to the invention consists in that a laminate of a carrier film and an active substance film is provided and pulled off, the carrier film being detached from the active substance film and wound up separately. The active substance film is also moved forward by the preferred movement of the carrier film. With its front end, it is guided between two stationary packaging material webs without mechanical stress, fixed by these and cross-cut to produce the wafer at a predetermined rearward distance from these. Subsequently, the wafer fixed between the packaging material webs is advanced together and synchronously with the latter, the preferential force acting on the packaging material webs, and fed to a sealing station. In this sealing station, the packaging material webs are sealed outside the arrangement area of the wafer to form a bag, which is then separated from the packaging material webs. In a known manner, the laminate is produced in the coating process and then cut into strips, which are wound up, the width of a coil corresponding to the width of the desired wafer or a multiple of this wafer width. If several wafers are cut out of the coil, the individual wafers are spread and brought to the width that is necessary to insert them into the packaging material webs. The spool is provided as a supply spool. The particular advantage of the method is that the wafer is transported and guided without mechanical stress. The method is carried out in such a way that the respective preferred length of the carrier film and thus also of the active substance film corresponds to the desired length of a wafer, so that the wafers are extremely precisely reproducible and always the same. This means that every wafer has the same dose of active ingredient. The separated wafer is then held in place during the preferred movement of the packaging material webs over its entire extent and is not mechanically stressed in the process. When the packaging material webs are sealed into a bag, there is no risk of damage to the wafer fixed between them. The procedure is easy to do.
In einer bevorzugten Ausführung wird der von der Träger- folie gelöste Wirkstofffilm in vertikaler Ausrichtung zwischen die bei diesem Verfahrensschritt ruhenden und im Abstand voneinander angeordneten Packstoffbahnen geführt. Anschließend werden diese an den Wafer angelegt und mit gleicher Vo Zugsgeschwindigkeit und in gleicher Vorzugs- richtung beidseits des Wirkstofffilms vorgezogen, so daß der Wirkstofffilm mechanisch unbelastet zwischen den Packstoffbahnen mit vorgezogen wird. Am Einlauf des Wirkstoff- films werden die Packstoffbahnen dabei durch eine Klemmvorrichtung geführt, die die Packstoffbahnen am Ende des Arbeitstaktes, bei dem der Wirkstofffilm mit seinem vorderen Ende zwischen die Packstoffbahnen verbracht wurde, an den Wafer andrückt und fixiert. Eine Relativbewegung zwischen diesem und den Packstoffbahnen ist dadurch ausgeschlossen. In dieser Position wird der Wirkstofffilm im vorbestimmten Abstand von der Klemmstation zur Abtrennung eines Wafers quergeschnitten und im nächsten Arbeitsschritt vollständig und belastungsfrei zwischen die Packstoffbahnen eingezogen und mit vorgezogen.In a preferred embodiment, the active substance film detached from the carrier film is guided in a vertical orientation between the packaging material webs which are at a standstill and arranged at a distance from one another in this method step. Then they are placed on the wafer and pulled forward at the same speed and in the same preferred direction on both sides of the active substance film, so that the active substance film is pulled mechanically unloaded between the packaging material webs. At the infeed of the active substance film, the packaging material webs are guided through a clamping device which engages the packaging material webs at the end of the working cycle in which the front end of the active substance film was placed between the packaging material webs presses and fixes the wafer. A relative movement between this and the packaging material webs is excluded. In this position, the active substance film is cut at a predetermined distance from the clamping station to separate a wafer, and in the next work step is drawn between the packaging material webs completely and without stress and pulled forward.
Die Vorrichtung zur Durchführung des Verfahrens weist in bekannter Weise eine VorratSeinrichtung für das aus einer Trägerfolie und einem Wirkstofffilm gebildete Laminat, ein Trennwerkzeug zum Ablösen des Wirkstofffilms von der Tragerfolie, eine Vorzugseinrichtung für diese und damit auch den Wirkstofffilm, ein Schneidwerkzeug für diesen, eine Packstoffzuführ- und -vorzugseinrichtung für zweiThe device for carrying out the method has, in a known manner, a storage device for the laminate formed from a carrier film and an active substance film, a separating tool for detaching the active substance film from the carrier film, a preferred device for this and thus also the active substance film, a cutting tool for the latter, a packaging material feed - and preferential arrangement for two
Packstoffbahnen, die auch von einer Packstoffrolle kommen und mittels eines Trennverfahrens vereinzelt und umgelenkt werden können, ein beheiztes Siegelwerkzeug für den Packstoff und ein Schneidwerkzeug zum Abtrennen des fertigen Siegelrandbeutels auf. Erfindungsgemäß ist die Pack- stoffzuführ- und -vorzugseinrichtung mit einer Aufnahme- und Klemmvorrichtung für das vordere Ende des Wirkstoff- films versehen, die in vertikaler Richtung unter dem Trennwerkzeug zum Ablösen des Wirkstoff ilms und dem Schneidwerkzeug für diesen angeordnet ist, derart, daß der von der Trägerfolie gelöste Wirkstofffilm während eines Vorschubtaktes in vertikaler Richtung nach unten in die Aufnahme- und Klemmvorrichtung gelangt. Dabei wird der Wirkstofffilm mechanisch nicht belastet.Packing material webs, which also come from a packaging material roll and can be separated and deflected by means of a separation process, have a heated sealing tool for the packaging material and a cutting tool for separating the finished sealed edge bag. According to the invention, the packaging material feed and feed device is provided with a receiving and clamping device for the front end of the active substance film, which is arranged in the vertical direction under the separating tool for detaching the active substance and the cutting tool for it, such that the Active substance film detached from the carrier film reaches the receiving and clamping device in a vertical direction downwards during a feed stroke. The drug film is not mechanically loaded.
Die Aufnahme- und Klemmvorrichtung ist bevorzugt aus Klemmrollen gebildet, zwischen denen die Packstoffbahnen gespannt geführt sind und die zwischen einer Aufnahmestellung für den Wirkstofffilm und einer Klemmstellung für diesen in horizontaler Richtung und somit quer zur Vorzugsrichtung des Wirkstofffilms gegenläufig zueinander be- wegbar sind. Zur Bildung eines Einlauftrichters für den Wirkstofffilm können dabei zwei Paare von Klemmrollen übereinander angeordnet sein.The receiving and clamping device is preferably formed from clamping rollers, between which the packaging material webs are tensioned and which act in opposite directions to one another between a receiving position for the active substance film and a clamping position for the latter in the horizontal direction and thus transversely to the preferred direction of the active substance film. are movable. Two pairs of pinch rollers can be arranged one above the other to form an inlet funnel for the active substance film.
Die Erfindung wird nachstehend anhand eines Ausführungsbeispiels erläutert. In den zugehörigen Zeichnungen zeigen schematisch:The invention is explained below using an exemplary embodiment. The accompanying drawings show schematically:
Fig.1:eine Vorrichtung zur Herstellung einer primären Einzelverpackung eines Wafers undFig.1: a device for producing a primary individual packaging of a wafer and
Fig.2 bis 5: eine zugehörige Aufnahme- und Klemmvorrichtung für en Wafer in aufeinanderfolgen Verfahrensschritten.2 to 5: an associated receiving and clamping device for en wafers in successive method steps.
Die in Fig. 1 gezeigte Vorrichtung weist eingangsseitig eine Vorratsspule 1 mit vorzuziehendem, aus einer Trägerfolie 2 und einem Wirkstofffilm 3 bestehendem Laminat 4, eine Umlenkrolle 5 und einen Abstreifer 6 zum Ablösen des Wirkstofffilms 3 von der Trägerfolie 2 und eine Spule 8 zum ' Aufwickeln der Trägerfolie 2 auf. Unter der Trennrolle 7 sind zum exakten Ausrichten des von der Trägerfolie 2 gelösten Wirkstofffilms 3 Führungsbahnen oder -leisten 9, eine Querschneidvorrichtung 10 mit einem Messer (nicht weiter dargestellt) und eine Packstoffzuführ- und -vorzugs- einrichtung 11 für zwei Packstoffbahnen 12 angeordnet, die schneidvorrichtungsseitig eine aus zwei Paaren von übereinander angeordneten Klemmrollen 13 und 14 gebildete Aufnahme- und Klemmvorrichtung aufweist. Die Packstoffbahnen 12 sind auf Vorratsrollen 15 angeordnet und über die Klemmrollen 13 und 14 zu Vorzugsrollen 16 geführt, durch die sie klemmend fixiert sind und vorgezogen werden, wodurch sie auch gespannt an den Klemmrollen 13 und 14 anliegen. Zwischen diesen (13, 14) und den Vorzugsrollen 16 sind beheizte Quersiegel- und Längssiegelwerkzeuge 17 und 18 und in Vorzugsrichtung nach den Vorzugsrollen 16 ein Flachmesser 19 als Querschneidwerkzeug angeordnet. Zur Herstellung einer primären Einzelverpackung eines Wafers wird Laminat 4 mit der vorbestimmten Breite des Wafers in der vorbestimmten Länge desselben von der Vorratsspule 1 durch eine Betätigung der Spule 8 abgezogen. Dabei wird der Wirkstofffilm 3 durch die Trennwalze 7 von der Trägerfolie 2 gelöst und vertikal nach unten durch die Führungsbahnen oder -leisten 9 ausgerichtet, wobei diese keine Klemmfunktion gegenüber dem Wirkstofffilm 3 haben. Bei diesem Vorgang gelangt das vordere Ende des Wirkstoff- films 3 zwischen die in ihrer Aufnahmeposition im Abstand voneinander befindlichen Klemmrollen 13 und 14, über die wirkstofffilmseitig die Packstoffbahnen 12 geführt sind und in der Aufnahmeposition gespannt an diesen anliegen. Die Packstoffbahnen 12 sind vom vorhergehenden Zyklus mit einer Quersiegelnaht 20 versehen, die nun die Front- oder Bodennaht des herzustellenden Siegelrandbeutels bzw. der primären Einzelverpackung des Wafers darstellt. Dieser Verfahrensschritt ist in Fig. 2 dargestellt. Im nächsten Verfahrensschritt (Fig. 3) werden die Packstoffbahnen 12 durch die Klemmrollen 13, 14 an den vorderen Bereich des vorgezogenen Wirkstofffilms 3 angedrückt und dieser zwischen den Packstoffbahnen 12 fixiert, indem diese (13, 14) aufeinander zu bewegt werden. Vom Wirkstofffilm 3 wird nun ein Wafer 21 in der vorbestimmten Länge durch die Quer- schneidvorrichtung 10 abgetrennt. Danach werden die Packstoffbahnen 12 mit dem zwischen diesen geklemmten Wafer durch eine synchrone Betätigung der Vorzugsrollen 16 bis zur Position der rückseitigen Quersiegelnaht vorgezogen (Fig. 4), wobei der Wafer 21 reibungsfrei und mit der gleichen Geschwindigkeit wie die Packstoffbahnen 12 bewegt wird. In dieser Position werden die Packstoffbahnen 12 an den beiden Längsseiten durch die beidenThe device shown in FIG. 1 has on the input side a supply reel 1 with a preferred laminate 4 consisting of a carrier film 2 and an active substance film 3, a deflection roller 5 and a stripper 6 for detaching the active substance film 3 from the carrier film 2 and a spool 8 for winding the carrier film 2. Under the separating roller 7 for exact alignment of the active substance film detached from the carrier film 2 3 guide tracks or strips 9, a cross cutting device 10 with a knife (not shown further) and a packaging material feed and preference device 11 for two packaging material tracks 12 are arranged on the cutting device side has a receiving and clamping device formed from two pairs of clamping rollers 13 and 14 arranged one above the other. The packaging material webs 12 are arranged on supply rolls 15 and are guided via the clamping rolls 13 and 14 to preferred rolls 16, by means of which they are fixed in a clamping manner and are advanced, whereby they also bear tightly against the clamping rolls 13 and 14. Heated transverse sealing and longitudinal sealing tools 17 and 18 are arranged between these (13, 14) and the preferred rollers 16 and a flat knife 19 as a transverse cutting tool in the preferred direction after the preferred rollers 16. In order to produce a primary individual packaging of a wafer, laminate 4 with the predetermined width of the wafer in the predetermined length thereof is drawn off from the supply spool 1 by actuating the spool 8. In this case, the active substance film 3 is detached from the carrier film 2 by the separating roller 7 and aligned vertically downward through the guide tracks or strips 9, these having no clamping function in relation to the active substance film 3. In this process, the front end of the active substance film 3 passes between the clamping rollers 13 and 14, which are at a distance from one another in their receiving position, via which the packaging material webs 12 are guided on the active substance film side and bear tightly against them in the receiving position. From the previous cycle, the packaging material webs 12 are provided with a transverse sealing seam 20 which now represents the front or bottom seam of the sealed edge bag to be produced or the primary individual packaging of the wafer. This process step is shown in FIG. 2. In the next process step (FIG. 3), the packaging material webs 12 are pressed by the clamping rollers 13, 14 onto the front area of the drawn-out active substance film 3 and this is fixed between the packaging material webs 12 by moving them (13, 14) towards one another. A wafer 21 in the predetermined length is now separated from the active substance film 3 by the cross-cutting device 10. Thereafter, the packaging material webs 12 with the wafer clamped between them are advanced by a synchronous actuation of the preferred rollers 16 to the position of the rear transverse sealing seam (FIG. 4), the wafer 21 being moved smoothly and at the same speed as the packaging material webs 12. In this position, the packaging material webs 12 are on the two long sides by the two
Längssiegelwerkzeuge 18 und an der hinteren Querseite durch das Quersiegelwerkzeug 17 miteinander heißversiegelt. Die entstehende Quersiegelnaht ist dabei so breit gewählt, daß diese quergeteilt werden kann und sowohl die rückseitige Siegelnaht der gerade gefertigten, jedoch noch zu vereinzelnden primären Einzelverpackung als auch die Fornt- oder Bodennaht der nachfolgenden EinzelVerpackung ergibt. Im Anschluß an das Siegeln werden die Klemmrollen 13, 14 in ihre Aufnahmeposition verbracht und somit geöffnet. In Fig. 5 ist dieser Verfahrensschritt dargestellt. Der nächste Zyklus beginnt wieder mit dem Einführen des Wirkstofffilms zwischen die in der Aufnahmeposition befindlichen Klemmrollen 13 und 14, wie vorstehend beschrieben ist. Nach jedem Zyklus wird eine auf diese Weise hergestellte primäre Einzelverpackung 22 eines Wafers 21 durch das Flachmesser 19 von der nachfolgenden Einzelverpackung abgetrennt. Longitudinal sealing tools 18 and heat-sealed to one another on the rear transverse side by the transverse sealing tool 17. The resulting transverse sealing seam is chosen so wide that it can be cross-divided and both the back Sealed seam of the primary individual packaging that has just been manufactured, but still has to be separated, as well as the shape or bottom seam of the subsequent individual packaging. Following the sealing, the pinch rollers 13, 14 are brought into their receiving position and thus opened. This method step is shown in FIG. The next cycle begins again with the introduction of the active substance film between the pinch rollers 13 and 14 located in the receiving position, as described above. After each cycle, a primary individual package 22 of a wafer 21 produced in this way is separated from the subsequent individual package by the flat knife 19.
B E Z U G S Z E I C H E N L I S T EB E Z U G S Z E I C H E N L I S T E
Vorratsspule Trägerfolie Wirkstofffilm Laminat Umlenkrolle Abstreifer Trennrolle Spule Führungsbahnen oder -leisten QuerSchneidvorrichtung Packstoffzuführ- und -vorzugseinrichtung Packstoffbahn Klemmrolle Klemmrolle Vorratsrolle Vorzugsrolle Quersiegelwerkzeug Längssiegelwerkzeug Flachmesser Quersiegelnaht Wafer Einzelverpackung Supply reel Carrier film Active ingredient film Laminate Deflection roller Scraper Separating roller Coil Guideways or strips Cross cutting device Packaging material feed and feed device Packing material web Clamping roller Clamping roller Storage roll Preference roller Cross sealing tool Longitudinal sealing tool Flat knife Cross sealing seam Wafer single packaging

Claims

P A T E N TAN S P RÜ C H E PATEN TAN SP RUCHE
1. Verfahren zur Herstellung einer primären Einzelverpackung eines Wafers, bei dem ein Laminat aus einer Trägerfolie und einem Wirkstofffilm bereitgestellt wird, der Wirkstofffilm mit vorbestimmter Länge quergeschnitten und von der Trägerfolie gelöst wird, zwischen zwei Packstoffbahnen geführt und mit diesen einer Siegelstation zugeführt wird, die Packstoff- bahnen zu einem Beutel gesiegelt und dieser von den Packstoffbahnen abgetrennt wird, dadurch gekennzeichnet, daß die vom Wirkstofffilm (3) gelöste Trägerfolie (2) in der vorbestimmten Länge des Wafers (21) vorgezogen und gleichzeitig der von dieser gelöste Wirkstofffilm (3) mit seinem vorderen Ende mechanisch belastungsfrei zwischen die ruhenden Packstoffbahnen (12) geführt, von diesen aufgenommen und fixiert und im Abstand von diesen zu einem Wafer (21) mit der vorbestimmten Länge quergesσhnitten wird, und daß anschließend der Wafer (21) gemeinsam und synchron mit den Packstoffbahnen (12) vorgezogen und der Siegelstation (17/ 18) zugeführt wird, in der die Packstoffbahnen (12) außerhalb des Bereiches des zwischen diesen fixierten Wafers (21) gesiegelt werden.1. A method for producing a primary individual packaging of a wafer, in which a laminate of a carrier film and a drug film is provided, the drug film is cut with a predetermined length and released from the carrier film, guided between two packaging material webs and fed to a sealing station with these Sealed packaging material webs to form a bag and this is separated from the packaging material webs, characterized in that the carrier film (2) detached from the active substance film (3) is advanced to the predetermined length of the wafer (21) and at the same time the active substance film (3) detached therefrom with its front end mechanically stress-free between the stationary packaging material webs (12), picked up and fixed by them and at a distance from them to a wafer (21) with the predetermined length is cross-cut, and then the wafer (21) together and synchronously with preferred the packaging material webs (12) and the seal station (17/18) is supplied, in which the packaging material webs (12) are sealed outside the area of the wafer (21) fixed between them.
2. Verfahren nach Anspruch 1, dadurch gekennzeichnet, daß der von der Trägerfolie (2) gelöste Wirkstofffilm (3) in vertikaler Ausrichtung zwischen die beidseits desselben einlaufenden Packstoffbahnen (12) geführt wird.2. The method according to claim 1, characterized in that the active substance film (3) detached from the carrier film (2) is guided in a vertical orientation between the packaging material webs (12) entering the same on both sides.
3. Verfahren nach Anspruch 1 oder 2, dadurch gekennzeichnet, daß das Lösen des Wirkstoff ilmes (3) von der vorgezogenen Trägerfolie (2) an einer Kante oder Umlenkrolle (5) erfolgt. 3. The method according to claim 1 or 2, characterized in that the release of the active ingredient ilmes (3) from the advanced carrier film (2) on an edge or deflection roller (5).
4. Verfahren nach Anspruch 3, dadurch gekennzeichnet, daß das Lösen des Wirkstofffilmes (3) von der Trägerfolie4. The method according to claim 3, characterized in that the detachment of the active substance film (3) from the carrier film
(2) mit Unterstützung eines Abstreifers (6) erfolgt, der zwischen dem Wirkstofffilm (3) und der Trägerfolie (2) angeordnet ist.(2) with the support of a stripper (6), which is arranged between the active substance film (3) and the carrier film (2).
5. Verfahren nach Anspruch 1, dadurch gekennzeichnet, daß die Packstoffbahnen (12) am Einlauf des Wirkstofffilms (3) in die Packstoffzuführ- und -vorzugseinrichtung5. The method according to claim 1, characterized in that the packaging material webs (12) at the inlet of the active substance film (3) into the packaging material feed and preference device
(11) über eine Klemmvorrichtung (13/ 14) geführt sind, durch die die Packstoffbahnen (12) während des Abtrennens des Wafers (21) vom Wirkstofffilm (3) und während ihres nachfolgenden Vorzuges an diesen derart angedrückt werden, daß eine Relativbewegung zwischen dem Wafer (21) und den Packstoffbahnen (12) ausgeschlossen ist .(11) are guided via a clamping device (13/14) through which the packaging material webs (12) are pressed against the active substance film (3) during the separation of the wafer (21) and during their subsequent preference in such a way that a relative movement between the Wafer (21) and the packaging material webs (12) is excluded.
6. Vorrichtung zur Durchführung des Verfahrens zur Her- Stellung einer primären Einzelverpackung eines Wafers, mit einer Vorratseinrichtung für ein Laminat aus einem Wirkstofffilm und einer Trägerfolie, einer Trennrolle zum Ablösen des Wirkstofffilms von der Trägerfolie, einer Vorzugseinrichtung für die Trägerfolie und damit auch den Wirkstofffilm, einer Querschneidvorrichtung für den Wirkstofffilm, einer Packstoffzuführ- und - vorzugseinrichtung für zwei Packstoffbahnen, einem beheizten Siegelwerkzeug für den Packstoff und mit einem Schneidwerkzeug zum Abtrennen des Siegelbeutels, dadurch gekennzeichnet, daß die Packstoffzuführ- und -vorzugseinrichtung (11) mit einer Aufnahme- und Klemmvorrichtung (13/ 14) für das vordere Ende des Wirkstofffilms (3) versehen ist, die in vertikaler Richtung unter der Trennrolle(7) und der Querschneid- Vorrichtung (10) angeordnet ist. 6.Device for carrying out the method for producing a primary individual packaging of a wafer, with a storage device for a laminate of an active substance film and a carrier film, a separating roller for detaching the active substance film from the carrier film, a preferred device for the carrier film and thus also the active substance film , a cross cutting device for the active ingredient film, a packaging material feed and - preference device for two packaging material webs, a heated sealing tool for the packaging material and with a cutting tool for separating the sealing bag, characterized in that the packaging material feed and preference device (11) with a receiving and Clamping device (13/14) for the front end of the active substance film (3) is provided, which is arranged in the vertical direction under the separating roller (7) and the cross-cutting device (10).
. Vorrichtung nach Anspruch 6, dadurch gekennzeichnet, daß die Aufnahme- und Klemmvorrichtung aus Klemmrollen, Apparatus according to claim 6, characterized in that the receiving and clamping device made of pinch rollers
(13, 14) gebildet ist, zwischen denen die Packstoffbahnen (12) geführt sind, wobei die Klemmrollen (13, 14) zwischen einer Auf ahmestellung und einer Klemmstellung für den Wirkstofffilm (3) quer zu diesem gegenläufig zueinander bewegbar sind.(13, 14) is formed, between which the packaging material webs (12) are guided, the pinch rollers (13, 14) between an up position and a clamping position for the active substance film (3) can be moved in opposite directions to one another transversely thereto.
8. Vorrichtung nach Anspruch 8, dadurch gekennzeichnet, daß zwei Paare von Klemmrollen (13, 14) übereinander angeordnet sind. 8. The device according to claim 8, characterized in that two pairs of pinch rollers (13, 14) are arranged one above the other.
EP03757797A 2002-09-16 2003-09-06 Method and device for producing a primary individual packing of a wafer Expired - Lifetime EP1539583B1 (en)

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DE10249705A DE10249705A1 (en) 2002-09-16 2002-10-25 Individual packaging method for oral medicament wafers has wafer lengths separated from carrier foil and wafer film laminate fed between packaging webs sealed together for providing packaging bag
PCT/EP2003/009911 WO2004026692A1 (en) 2002-09-16 2003-09-06 Method and device for producing a primary individual packing of a wafer

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RU2005103607A (en) 2005-07-20
WO2004026692A1 (en) 2004-04-01
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PL375880A1 (en) 2005-12-12
DE50305600D1 (en) 2006-12-14

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