EP1372553A4 - Hydrogele, die als reaktion auf veränderungen in der umgebung einer volumetrischen expansion unterzogen werden und ihre herstellungs- und verwendungsmethoden - Google Patents
Hydrogele, die als reaktion auf veränderungen in der umgebung einer volumetrischen expansion unterzogen werden und ihre herstellungs- und verwendungsmethodenInfo
- Publication number
- EP1372553A4 EP1372553A4 EP02750563A EP02750563A EP1372553A4 EP 1372553 A4 EP1372553 A4 EP 1372553A4 EP 02750563 A EP02750563 A EP 02750563A EP 02750563 A EP02750563 A EP 02750563A EP 1372553 A4 EP1372553 A4 EP 1372553A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- hydrogels
- manufacture
- environment
- response
- methods
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F22/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides or nitriles thereof
- C08F22/36—Amides or imides
- C08F22/38—Amides
- C08F22/385—Monomers containing two or more (meth)acrylamide groups, e.g. N,N'-methylenebisacrylamide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
- A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
- A61K49/0457—Semi-solid forms, ointments, gels, hydrogels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/145—Hydrogels or hydrocolloids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Vascular Medicine (AREA)
- Surgery (AREA)
- Materials For Medical Uses (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
- Medicinal Preparation (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP10188630A EP2308431B1 (de) | 2001-03-13 | 2002-02-28 | Hydrogel, das sich mit Änderungen der Umweltbedingungen ausdehnt, Herstellungsmethoden und Verwendungen für das Hydrogel. |
EP10188595.2A EP2363104B1 (de) | 2001-03-13 | 2002-02-28 | Hydrogele, die auf Änderungen in ihrer Umgebung mit einer Volumenexpansion reagieren, ihre Herstellung und Verwendung |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/804,935 US6878384B2 (en) | 2001-03-13 | 2001-03-13 | Hydrogels that undergo volumetric expansion in response to changes in their environment and their methods of manufacture and use |
US804935 | 2001-03-13 | ||
PCT/US2002/005988 WO2002071994A1 (en) | 2001-03-13 | 2002-02-28 | Hydrogels that undergo volumetric expansion in response to changes in their environment and their methods of manufacture and use |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP10188595.2A Division-Into EP2363104B1 (de) | 2001-03-13 | 2002-02-28 | Hydrogele, die auf Änderungen in ihrer Umgebung mit einer Volumenexpansion reagieren, ihre Herstellung und Verwendung |
EP10188630A Division-Into EP2308431B1 (de) | 2001-03-13 | 2002-02-28 | Hydrogel, das sich mit Änderungen der Umweltbedingungen ausdehnt, Herstellungsmethoden und Verwendungen für das Hydrogel. |
Publications (3)
Publication Number | Publication Date |
---|---|
EP1372553A1 EP1372553A1 (de) | 2004-01-02 |
EP1372553A4 true EP1372553A4 (de) | 2006-04-12 |
EP1372553B1 EP1372553B1 (de) | 2014-06-25 |
Family
ID=25190260
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP10188630A Expired - Lifetime EP2308431B1 (de) | 2001-03-13 | 2002-02-28 | Hydrogel, das sich mit Änderungen der Umweltbedingungen ausdehnt, Herstellungsmethoden und Verwendungen für das Hydrogel. |
EP10188595.2A Expired - Lifetime EP2363104B1 (de) | 2001-03-13 | 2002-02-28 | Hydrogele, die auf Änderungen in ihrer Umgebung mit einer Volumenexpansion reagieren, ihre Herstellung und Verwendung |
EP02750563.5A Expired - Lifetime EP1372553B1 (de) | 2001-03-13 | 2002-02-28 | Hydrogele, die als reaktion auf veränderungen in der umgebung einer volumetrischen expansion unterzogen werden und ihre herstellungs- und verwendungsmethoden |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP10188630A Expired - Lifetime EP2308431B1 (de) | 2001-03-13 | 2002-02-28 | Hydrogel, das sich mit Änderungen der Umweltbedingungen ausdehnt, Herstellungsmethoden und Verwendungen für das Hydrogel. |
EP10188595.2A Expired - Lifetime EP2363104B1 (de) | 2001-03-13 | 2002-02-28 | Hydrogele, die auf Änderungen in ihrer Umgebung mit einer Volumenexpansion reagieren, ihre Herstellung und Verwendung |
Country Status (9)
Country | Link |
---|---|
US (5) | US6878384B2 (de) |
EP (3) | EP2308431B1 (de) |
JP (2) | JP4416151B2 (de) |
CN (2) | CN1306916C (de) |
AU (3) | AU2002306605B2 (de) |
BR (1) | BRPI0208034B8 (de) |
CA (1) | CA2439925C (de) |
ES (3) | ES2408014T3 (de) |
WO (1) | WO2002071994A1 (de) |
Families Citing this family (132)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2014200734B2 (en) * | 2001-03-13 | 2015-11-05 | Microvention, Inc. | Hydrogels that undergo volumetric expansion in response to changes in their environment and their methods of manufacture and use |
US6878384B2 (en) | 2001-03-13 | 2005-04-12 | Microvention, Inc. | Hydrogels that undergo volumetric expansion in response to changes in their environment and their methods of manufacture and use |
AU2002305401A1 (en) * | 2001-05-04 | 2002-11-18 | Concentric Medical | Hydrogel filament vaso-occlusive device |
AU2002345795B2 (en) * | 2001-06-20 | 2008-01-10 | Microvention, Inc. | Medical devices having full or partial polymer coatings and their methods of manufacture |
US7572288B2 (en) | 2001-07-20 | 2009-08-11 | Microvention, Inc. | Aneurysm treatment device and method of use |
US8252040B2 (en) * | 2001-07-20 | 2012-08-28 | Microvention, Inc. | Aneurysm treatment device and method of use |
MXPA04007428A (es) * | 2002-02-01 | 2004-10-11 | Pfizer Prod Inc | Formas de dosificacion de liberacion inmediata que contienen dispersiones de farmaco solido. |
US8425549B2 (en) | 2002-07-23 | 2013-04-23 | Reverse Medical Corporation | Systems and methods for removing obstructive matter from body lumens and treating vascular defects |
US7551749B2 (en) | 2002-08-23 | 2009-06-23 | Bose Corporation | Baffle vibration reducing |
DE10330269A1 (de) * | 2003-07-04 | 2005-01-27 | Instraction Gmbh | System umfassend Effektoren und volumenveränderbare Rezeptoren-modifizierte Elastomere, Verfahren zu ihrer Herstellung und ihrer Verwendung |
JP2007509716A (ja) * | 2003-10-29 | 2007-04-19 | ジェンティス インコーポレイテッド | 組織工学用の重合可能なエマルション |
CA2558623C (en) * | 2004-02-06 | 2013-04-16 | Georgia Tech Research Corporation | Surface directed cellular attachment |
CA2558661C (en) | 2004-02-06 | 2012-09-04 | Georgia Tech Research Corporation | Load bearing biocompatible device |
CA2758946C (en) | 2004-05-25 | 2014-10-21 | Tyco Healthcare Group Lp | Vascular stenting for aneurysms |
US9675476B2 (en) | 2004-05-25 | 2017-06-13 | Covidien Lp | Vascular stenting for aneurysms |
CA2565106C (en) | 2004-05-25 | 2013-11-05 | Chestnut Medical Technologies, Inc. | Flexible vascular occluding device |
WO2006028370A1 (en) * | 2004-09-10 | 2006-03-16 | Stichting Dutch Polymer Institute | Radiopaque prosthetic intervertebral disc nucleus |
US7201918B2 (en) * | 2004-11-16 | 2007-04-10 | Microvention, Inc. | Compositions, systems and methods for treatment of defects in blood vessels |
US7419486B2 (en) * | 2005-06-15 | 2008-09-02 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Treatment and diagnostic catheters with hydrogel electrodes |
GB0523999D0 (en) * | 2005-11-25 | 2006-01-04 | Univ Manchester | Microgel particle |
US7959676B2 (en) * | 2006-02-13 | 2011-06-14 | Lanx, Inc. | Method and apparatus for intervertebral disc support and repair |
US8152833B2 (en) | 2006-02-22 | 2012-04-10 | Tyco Healthcare Group Lp | Embolic protection systems having radiopaque filter mesh |
JP2010500917A (ja) | 2006-06-15 | 2010-01-14 | マイクロベンション, インコーポレイテッド | 膨張性ポリマーで構成される塞栓形成デバイス |
US8771713B2 (en) | 2007-03-12 | 2014-07-08 | Board Of Regents, The University Of Texas System | Method and process for the production of multi-coated recognitive and releasing systems |
US8821899B2 (en) | 2007-03-12 | 2014-09-02 | Board Of Regents, The University Of Texas System | Method and process for the production of multi-coated recognitive and releasing systems |
US8741316B2 (en) * | 2007-03-12 | 2014-06-03 | Board Of Regents, The University Of Texas System | Highly porous, recognitive polymer systems |
US9155703B2 (en) | 2007-03-12 | 2015-10-13 | Board Of Regents, The University Of Texas System | Method and process for the production of multi-coated recognitive and releasing systems |
WO2008151204A1 (en) * | 2007-06-04 | 2008-12-11 | Sequent Medical Inc. | Methods and devices for treatment of vascular defects |
EP2162101B1 (de) | 2007-06-25 | 2019-02-20 | MicroVention, Inc. | Selbstexpandierende prothese |
BRPI0821070B1 (pt) * | 2007-12-21 | 2018-10-23 | Microvention Inc | dispositivo para implantação e método para a preparação de um filamento de hidrogel para implantação em um animal |
WO2009108760A2 (en) * | 2008-02-26 | 2009-09-03 | Board Of Regents, The University Of Texas System | Dendritic macroporous hydrogels prepared by crystal templating |
EP2265193B1 (de) | 2008-04-21 | 2011-11-16 | NFocus Neuromedical, Inc. | Kugelgeflecht-embolievorrichtung und -ausgabesysteme |
JP2011519632A (ja) * | 2008-05-02 | 2011-07-14 | シークエント メディカル, インコーポレイテッド | 血管障害の治療のためのフィラメントデバイス |
WO2009140437A1 (en) | 2008-05-13 | 2009-11-19 | Nfocus Neuromedical, Inc. | Braid implant delivery systems |
US8180076B2 (en) * | 2008-07-31 | 2012-05-15 | Bose Corporation | System and method for reducing baffle vibration |
EP2172236A1 (de) * | 2008-10-03 | 2010-04-07 | Koninklijke Philips Electronics N.V. | Brustpumpsystem |
JP2010162063A (ja) * | 2009-01-13 | 2010-07-29 | Japan Health Science Foundation | 塞栓材 |
JP2012100680A (ja) * | 2009-03-04 | 2012-05-31 | Terumo Corp | 血管内用処置材 |
JP2010227172A (ja) * | 2009-03-26 | 2010-10-14 | Terumo Corp | 軟組織増大材料 |
US10639396B2 (en) | 2015-06-11 | 2020-05-05 | Microvention, Inc. | Polymers |
US8409269B2 (en) | 2009-12-21 | 2013-04-02 | Covidien Lp | Procedures for vascular occlusion |
JP2013505791A (ja) * | 2009-09-24 | 2013-02-21 | マイクロベンション インコーポレイテッド | 医学的使用のための注射用ヒドロゲル繊維 |
JP5401254B2 (ja) * | 2009-10-13 | 2014-01-29 | 昌典 石原 | 多孔質合成樹脂製造方法および同多孔質合成樹脂製造方法により製造された多孔質合成樹脂材 |
US9993252B2 (en) | 2009-10-26 | 2018-06-12 | Microvention, Inc. | Embolization device constructed from expansile polymer |
AU2010315106A1 (en) * | 2009-11-05 | 2012-05-17 | Sequent Medical Inc. | Multiple layer filamentary devices or treatment of vascular defects |
US8337448B2 (en) | 2010-01-29 | 2012-12-25 | Baxter International Inc. | Apparatus for monitoring and controlling peritoneal dialysis |
EP2613735B1 (de) | 2010-09-10 | 2018-05-09 | Covidien LP | Vorrichtungen zur behandlung von gefässdefekten |
US8998947B2 (en) | 2010-09-10 | 2015-04-07 | Medina Medical, Inc. | Devices and methods for the treatment of vascular defects |
WO2012078678A1 (en) | 2010-12-06 | 2012-06-14 | Tyco Healthcare Group Lp | Vascular remodeling device |
US20120245674A1 (en) | 2011-03-25 | 2012-09-27 | Tyco Healthcare Group Lp | Vascular remodeling device |
WO2012145431A2 (en) | 2011-04-18 | 2012-10-26 | Microvention, Inc. | Embolic devices |
CA2835427A1 (en) | 2011-05-11 | 2012-11-15 | Microvention, Inc. | Device for occluding a lumen |
CN103547222B (zh) | 2011-05-11 | 2016-02-10 | 柯惠有限合伙公司 | 脉管重塑装置 |
US9155543B2 (en) | 2011-05-26 | 2015-10-13 | Cartiva, Inc. | Tapered joint implant and related tools |
US9060886B2 (en) | 2011-09-29 | 2015-06-23 | Covidien Lp | Vascular remodeling device |
US9072620B2 (en) | 2011-11-04 | 2015-07-07 | Covidien Lp | Protuberant aneurysm bridging device deployment method |
US9011480B2 (en) | 2012-01-20 | 2015-04-21 | Covidien Lp | Aneurysm treatment coils |
US9011884B2 (en) | 2012-04-18 | 2015-04-21 | Microvention, Inc. | Embolic devices |
US9452070B2 (en) | 2012-10-31 | 2016-09-27 | Covidien Lp | Methods and systems for increasing a density of a region of a vascular device |
EP2919668A2 (de) | 2012-11-13 | 2015-09-23 | Covidien LP | Verschlussvorrichtungen |
WO2014164357A1 (en) | 2013-03-11 | 2014-10-09 | Microvention, Inc. | Implantable device with adhesive properties |
CN105142543B (zh) | 2013-03-15 | 2019-06-04 | 柯惠有限合伙公司 | 血管植入物的输送与分离机构 |
US10736758B2 (en) | 2013-03-15 | 2020-08-11 | Covidien | Occlusive device |
US9955976B2 (en) | 2013-08-16 | 2018-05-01 | Sequent Medical, Inc. | Filamentary devices for treatment of vascular defects |
US9078658B2 (en) | 2013-08-16 | 2015-07-14 | Sequent Medical, Inc. | Filamentary devices for treatment of vascular defects |
US9963556B2 (en) | 2013-09-18 | 2018-05-08 | Senseonics, Incorporated | Critical point drying of hydrogels in analyte sensors |
JP6641265B2 (ja) * | 2013-09-19 | 2020-02-05 | マイクロベンション インコーポレイテッドMicrovention, Inc. | ポリマーフィルム |
JP6405369B2 (ja) * | 2013-09-19 | 2018-10-17 | テルモ株式会社 | ポリマー粒子 |
CN105916495B (zh) | 2013-11-08 | 2019-11-12 | 泰尔茂株式会社 | 聚合物颗粒 |
US9795400B2 (en) | 2013-11-13 | 2017-10-24 | Covidien Lp | Galvanically assisted attachment of medical devices to thrombus |
JP6456969B2 (ja) * | 2014-02-21 | 2019-01-23 | マサチューセッツ インスティテュート オブ テクノロジー | 膨張顕微鏡法 |
EP3113722A4 (de) * | 2014-03-07 | 2017-12-06 | Endologix, Inc. | Herstellung von hydrogelen und materialien dafür |
WO2015153996A1 (en) | 2014-04-03 | 2015-10-08 | Micro Vention, Inc. | Embolic devices |
US9629635B2 (en) | 2014-04-14 | 2017-04-25 | Sequent Medical, Inc. | Devices for therapeutic vascular procedures |
US9713475B2 (en) | 2014-04-18 | 2017-07-25 | Covidien Lp | Embolic medical devices |
WO2015167752A1 (en) * | 2014-04-29 | 2015-11-05 | Microvention, Inc. | Polymers including active agents |
US10092663B2 (en) | 2014-04-29 | 2018-10-09 | Terumo Corporation | Polymers |
US10959865B2 (en) | 2014-05-12 | 2021-03-30 | Jeffrey E. Thomas | Photo-activatable gel coated intracranial stent and embolic coil |
IL282559B (en) | 2014-07-17 | 2022-07-01 | Univ California | Self-reinforced and controllable microgel particles for biomedical applications |
US9814466B2 (en) | 2014-08-08 | 2017-11-14 | Covidien Lp | Electrolytic and mechanical detachment for implant delivery systems |
TW201625754A (zh) * | 2014-11-21 | 2016-07-16 | 艾倫塔斯有限公司 | 單一成份、儲存穩定、可硬化之聚矽氧組成物 |
WO2016154592A1 (en) * | 2015-03-26 | 2016-09-29 | Microvention, Inc. | Embiolic particles |
CA2981061A1 (en) | 2015-03-31 | 2016-10-06 | Cartiva, Inc. | Hydrogel implants with porous materials and methods |
AU2016243660B2 (en) | 2015-03-31 | 2020-11-12 | Cartiva, Inc. | Carpometacarpal (CMC) implants and methods |
US10526649B2 (en) | 2015-04-14 | 2020-01-07 | Massachusetts Institute Of Technology | Augmenting in situ nucleic acid sequencing of expanded biological samples with in vitro sequence information |
US11408890B2 (en) | 2015-04-14 | 2022-08-09 | Massachusetts Institute Of Technology | Iterative expansion microscopy |
US10059990B2 (en) | 2015-04-14 | 2018-08-28 | Massachusetts Institute Of Technology | In situ nucleic acid sequencing of expanded biological samples |
CA2981074C (en) | 2015-04-14 | 2023-03-28 | Cartiva, Inc. | Tooling for creating tapered opening in tissue and related methods |
WO2017023903A1 (en) * | 2015-08-03 | 2017-02-09 | President And Fellows Of Harvard College | Phase-transforming and switchable metamaterials |
WO2017027368A1 (en) | 2015-08-07 | 2017-02-16 | Massachusetts Institute Of Technology | Protein retention expansion microscopy |
EP3332029B1 (de) | 2015-08-07 | 2021-10-06 | Massachusetts Institute of Technology | Nanoskalige bildgebung von proteinen und nukleinsäuren durch expansionsmikroskopie |
US10478194B2 (en) | 2015-09-23 | 2019-11-19 | Covidien Lp | Occlusive devices |
US10314593B2 (en) | 2015-09-23 | 2019-06-11 | Covidien Lp | Occlusive devices |
CA3004745A1 (en) | 2015-11-12 | 2017-05-18 | University Of Virginia Patent Foundation | Compositions and methods for vas-occlusive contraception and reversal thereof |
WO2017142879A1 (en) | 2016-02-16 | 2017-08-24 | The Regents Of The University Of California | Methods for immune system modulation with microporous annealed particle gels |
WO2017165833A1 (en) | 2016-03-24 | 2017-09-28 | Covidien Lp | Thin wall constructions for vascular flow diversion |
US10828037B2 (en) | 2016-06-27 | 2020-11-10 | Covidien Lp | Electrolytic detachment with fluid electrical connection |
US10828039B2 (en) | 2016-06-27 | 2020-11-10 | Covidien Lp | Electrolytic detachment for implantable devices |
US11051822B2 (en) | 2016-06-28 | 2021-07-06 | Covidien Lp | Implant detachment with thermal activation |
US20180028715A1 (en) | 2016-07-27 | 2018-02-01 | Contraline, Inc. | Carbon-based compositions useful for occlusive medical devices and methods of making and using them |
US10478195B2 (en) | 2016-08-04 | 2019-11-19 | Covidien Lp | Devices, systems, and methods for the treatment of vascular defects |
EP4279139A3 (de) | 2016-09-28 | 2024-01-24 | Terumo Corporation | Polymerpartikel |
US20180206851A1 (en) * | 2016-10-19 | 2018-07-26 | Daniel E. Walzman | Hydrogel intrasaccular occlusion device |
US10576099B2 (en) | 2016-10-21 | 2020-03-03 | Covidien Lp | Injectable scaffold for treatment of intracranial aneurysms and related technology |
AU2017394923B2 (en) | 2016-12-29 | 2022-07-14 | Tempo Therapeutics, Inc. | Methods and systems for treating a site of a medical implant |
US11931928B2 (en) * | 2016-12-29 | 2024-03-19 | Evonik Superabsorber Llc | Continuous strand superabsorbent polymerization |
US10995361B2 (en) | 2017-01-23 | 2021-05-04 | Massachusetts Institute Of Technology | Multiplexed signal amplified FISH via splinted ligation amplification and sequencing |
US11385481B1 (en) | 2017-02-01 | 2022-07-12 | Ram Pattikonda | Advanced dynamic focus eyewear |
WO2018157048A1 (en) | 2017-02-24 | 2018-08-30 | Massachusetts Institute Of Technology | Methods for examining podocyte foot processes in human renal samples using conventional optical microscopy |
CA3058726A1 (en) * | 2017-04-05 | 2018-10-11 | Setbone Medical Ltd. | Property changing implant |
CN107158560A (zh) * | 2017-04-27 | 2017-09-15 | 清华大学 | 基于水凝胶溶胀特性的可控自变形神经微电极 |
WO2019023214A1 (en) | 2017-07-25 | 2019-01-31 | Massachusetts Institute Of Technology | ATAC IN SITU SEQUENCING |
US10675036B2 (en) | 2017-08-22 | 2020-06-09 | Covidien Lp | Devices, systems, and methods for the treatment of vascular defects |
WO2019082991A1 (ja) * | 2017-10-25 | 2019-05-02 | メディギア・インターナショナル株式会社 | 生体分解性及び生体代謝性の腫瘍封止剤 |
US11873374B2 (en) | 2018-02-06 | 2024-01-16 | Massachusetts Institute Of Technology | Swellable and structurally homogenous hydrogels and methods of use thereof |
US11065009B2 (en) | 2018-02-08 | 2021-07-20 | Covidien Lp | Vascular expandable devices |
US11065136B2 (en) | 2018-02-08 | 2021-07-20 | Covidien Lp | Vascular expandable devices |
US10905432B2 (en) | 2018-08-22 | 2021-02-02 | Covidien Lp | Aneurysm treatment coils and associated systems and methods of use |
US10912569B2 (en) | 2018-08-22 | 2021-02-09 | Covidien Lp | Aneurysm treatment coils and associated systems and methods of use |
CN111388044A (zh) | 2018-12-17 | 2020-07-10 | 柯惠有限合伙公司 | 闭塞装置 |
CN111393563B (zh) * | 2019-01-02 | 2023-04-07 | 湖南工业大学 | 一种温敏性水凝胶的制备方法及监测模具 |
CN111686310B (zh) * | 2019-03-11 | 2022-03-29 | 国家纳米科学中心 | 一种抗菌导尿管及其制备方法和应用 |
CN113573650B (zh) | 2019-03-15 | 2024-05-28 | 后续医疗股份有限公司 | 用于治疗血管缺陷的具有柔性连接部的丝装置 |
US11559309B2 (en) | 2019-03-15 | 2023-01-24 | Sequent Medical, Inc. | Filamentary devices for treatment of vascular defects |
CN113573765A (zh) | 2019-03-15 | 2021-10-29 | 后续医疗股份有限公司 | 用于治疗血管缺陷的丝装置 |
US11717924B2 (en) | 2019-11-04 | 2023-08-08 | Covidien Lp | Devices, systems, and methods for treatment of intracranial aneurysms |
WO2021113505A1 (en) | 2019-12-05 | 2021-06-10 | Massachusetts Institute Of Technology | Method for preparing a specimen for expansion microscopy |
CN111333866B (zh) * | 2020-03-20 | 2023-03-24 | 浙江理工大学 | 一种单层水凝胶、制备方法及用作柔性抓手的应用 |
US11931041B2 (en) | 2020-05-12 | 2024-03-19 | Covidien Lp | Devices, systems, and methods for the treatment of vascular defects |
CN112300413B (zh) * | 2020-12-29 | 2021-04-09 | 北京泰杰伟业科技有限公司 | 一种超细均匀的丙烯酰胺类聚合物水凝胶丝的制备方法及应用 |
CN114561237B (zh) * | 2022-04-19 | 2022-10-28 | 中国科学院兰州化学物理研究所 | 一种剪切响应性水基凝胶润滑剂的制备方法 |
CN115746360B (zh) * | 2022-11-24 | 2023-12-12 | 无锡学院 | 一种间隙可调的柔性表面增强拉曼散射基底及其制备方法和应用 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991004732A1 (en) * | 1989-10-03 | 1991-04-18 | Advanced Polymer Systems, Inc. | Erodible macroporous hydrogel particles and preparation thereof |
US5415864A (en) * | 1990-04-18 | 1995-05-16 | University Of Utah Research Foundation | Colonic-targeted oral drug-dosage forms based on crosslinked hydrogels containing azobonds and exhibiting PH-dependent swelling |
US5447727A (en) * | 1992-10-14 | 1995-09-05 | The Dow Chemical Company | Water-absorbent polymer having improved properties |
US5863551A (en) * | 1996-10-16 | 1999-01-26 | Organogel Canada Ltee | Implantable polymer hydrogel for therapeutic uses |
EP1024176A1 (de) * | 1998-08-13 | 2000-08-02 | Nippon Shokubai Co., Ltd. | Wasserquellbare vernetzte polymerzusammensetzung und verfahren zu deren herstellung |
Family Cites Families (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6005161A (en) | 1986-01-28 | 1999-12-21 | Thm Biomedical, Inc. | Method and device for reconstruction of articular cartilage |
US4990138A (en) * | 1989-07-18 | 1991-02-05 | Baxter International Inc. | Catheter apparatus, and compositions useful for producing same |
US5635482A (en) | 1989-08-14 | 1997-06-03 | The Regents Of The University Of California | Synthetic compounds and compositions with enhanced cell binding |
US5226902A (en) | 1991-07-30 | 1993-07-13 | University Of Utah | Pulsatile drug delivery device using stimuli sensitive hydrogel |
US5514379A (en) | 1992-08-07 | 1996-05-07 | The General Hospital Corporation | Hydrogel compositions and methods of use |
US5554147A (en) | 1994-02-01 | 1996-09-10 | Caphco, Inc. | Compositions and devices for controlled release of active ingredients |
US5651979A (en) | 1995-03-30 | 1997-07-29 | Gel Sciences, Inc. | Apparatus and method for delivering a biologically active compound into a biological environment |
US5750585A (en) | 1995-04-04 | 1998-05-12 | Purdue Research Foundation | Super absorbent hydrogel foams |
DE69623597T2 (de) | 1995-12-19 | 2003-05-22 | Bracco Research Sa | Tricodobenzene-polymere enthaltende zusammensetzungen zur abbildung des gastrointestinaltraktes |
PL335974A1 (en) | 1997-04-02 | 2000-06-05 | Purdue Research Foundation | Method of orally administering proteins |
US6224893B1 (en) * | 1997-04-11 | 2001-05-01 | Massachusetts Institute Of Technology | Semi-interpenetrating or interpenetrating polymer networks for drug delivery and tissue engineering |
US6271278B1 (en) * | 1997-05-13 | 2001-08-07 | Purdue Research Foundation | Hydrogel composites and superporous hydrogel composites having fast swelling, high mechanical strength, and superabsorbent properties |
US5891192A (en) | 1997-05-22 | 1999-04-06 | The Regents Of The University Of California | Ion-implanted protein-coated intralumenal implants |
US6077880A (en) * | 1997-08-08 | 2000-06-20 | Cordis Corporation | Highly radiopaque polyolefins and method for making the same |
DE69922352T2 (de) * | 1998-03-06 | 2005-12-15 | Biosphere Medical, Inc., Rockland | Implantierbare partikel zur erhöhung des gewebevolumens und zur behandlung von gastroösophagalreflux, inkontinenz und hautfalten |
US6165193A (en) * | 1998-07-06 | 2000-12-26 | Microvention, Inc. | Vascular embolization with an expansible implant |
KR20000012970A (ko) | 1998-08-03 | 2000-03-06 | 김효근 | 썰폰아마이드기를 포함하는 ph 민감성 고분자 및 그의 제조방법 |
US5952232A (en) | 1998-09-17 | 1999-09-14 | Rothman; James Edward | Expandible microparticle intracellular delivery system |
US6187024B1 (en) | 1998-11-10 | 2001-02-13 | Target Therapeutics, Inc. | Bioactive coating for vaso-occlusive devices |
US6245740B1 (en) | 1998-12-23 | 2001-06-12 | Amgen Inc. | Polyol:oil suspensions for the sustained release of proteins |
US6371904B1 (en) * | 1998-12-24 | 2002-04-16 | Vivant Medical, Inc. | Subcutaneous cavity marking device and method |
EP1031354A3 (de) | 1999-01-19 | 2003-02-05 | Rohm And Haas Company | Polymere MRI Kontrastmittel |
US6663607B2 (en) | 1999-07-12 | 2003-12-16 | Scimed Life Systems, Inc. | Bioactive aneurysm closure device assembly and kit |
US7291673B2 (en) | 2000-06-02 | 2007-11-06 | Eidgenossiche Technische Hochschule Zurich | Conjugate addition reactions for the controlled delivery of pharmaceutically active compounds |
US6506408B1 (en) * | 2000-07-13 | 2003-01-14 | Scimed Life Systems, Inc. | Implantable or insertable therapeutic agent delivery device |
US6878384B2 (en) | 2001-03-13 | 2005-04-12 | Microvention, Inc. | Hydrogels that undergo volumetric expansion in response to changes in their environment and their methods of manufacture and use |
EP2319430B1 (de) | 2001-05-29 | 2013-11-13 | Microvention, Inc. | Gerät zur vaskularen Embolisation und Verfahren zu dessen Herstellung |
US20030014075A1 (en) * | 2001-07-16 | 2003-01-16 | Microvention, Inc. | Methods, materials and apparatus for deterring or preventing endoleaks following endovascular graft implanation |
US20030134032A1 (en) | 2001-11-16 | 2003-07-17 | Hassan Chaouk | Methods for initiating in situ formation of hydrogels |
WO2003089506A1 (en) | 2002-04-22 | 2003-10-30 | Purdue Research Foundation | Hydrogels having enhanced elasticity and mechanical strength properties |
EP1526815A1 (de) | 2002-07-31 | 2005-05-04 | MicroVention, Inc. | Aus drei koaxiale elemente bestehende vaso-okklusionsvorrichtung |
US20050119687A1 (en) | 2003-09-08 | 2005-06-02 | Dacey Ralph G.Jr. | Methods of, and materials for, treating vascular defects with magnetically controllable hydrogels |
JP2010500917A (ja) | 2006-06-15 | 2010-01-14 | マイクロベンション, インコーポレイテッド | 膨張性ポリマーで構成される塞栓形成デバイス |
-
2001
- 2001-03-13 US US09/804,935 patent/US6878384B2/en not_active Expired - Lifetime
-
2002
- 2002-02-28 WO PCT/US2002/005988 patent/WO2002071994A1/en active IP Right Grant
- 2002-02-28 ES ES10188595T patent/ES2408014T3/es not_active Expired - Lifetime
- 2002-02-28 CN CNB028063848A patent/CN1306916C/zh not_active Expired - Lifetime
- 2002-02-28 CN CNA2007100077925A patent/CN101024729A/zh active Pending
- 2002-02-28 AU AU2002306605A patent/AU2002306605B2/en not_active Expired
- 2002-02-28 EP EP10188630A patent/EP2308431B1/de not_active Expired - Lifetime
- 2002-02-28 EP EP10188595.2A patent/EP2363104B1/de not_active Expired - Lifetime
- 2002-02-28 BR BRPI0208034A patent/BRPI0208034B8/pt not_active IP Right Cessation
- 2002-02-28 CA CA2439925A patent/CA2439925C/en not_active Expired - Lifetime
- 2002-02-28 EP EP02750563.5A patent/EP1372553B1/de not_active Expired - Lifetime
- 2002-02-28 ES ES10188630T patent/ES2390605T3/es not_active Expired - Lifetime
- 2002-02-28 ES ES02750563.5T patent/ES2478992T3/es not_active Expired - Lifetime
- 2002-02-28 JP JP2002570954A patent/JP4416151B2/ja not_active Expired - Lifetime
-
2005
- 2005-03-24 US US11/090,806 patent/US8231890B2/en active Active
-
2007
- 2007-09-07 AU AU2007216682A patent/AU2007216682B2/en not_active Ceased
-
2009
- 2009-09-10 AU AU2009213041A patent/AU2009213041A1/en not_active Abandoned
- 2009-10-01 JP JP2009229839A patent/JP5154529B2/ja not_active Expired - Lifetime
-
2012
- 2012-06-19 US US13/527,485 patent/US8465779B2/en not_active Expired - Lifetime
-
2013
- 2013-05-20 US US13/898,250 patent/US8734834B2/en not_active Expired - Fee Related
-
2014
- 2014-04-16 US US14/254,661 patent/US20140256837A1/en not_active Abandoned
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991004732A1 (en) * | 1989-10-03 | 1991-04-18 | Advanced Polymer Systems, Inc. | Erodible macroporous hydrogel particles and preparation thereof |
US5415864A (en) * | 1990-04-18 | 1995-05-16 | University Of Utah Research Foundation | Colonic-targeted oral drug-dosage forms based on crosslinked hydrogels containing azobonds and exhibiting PH-dependent swelling |
US5447727A (en) * | 1992-10-14 | 1995-09-05 | The Dow Chemical Company | Water-absorbent polymer having improved properties |
US5863551A (en) * | 1996-10-16 | 1999-01-26 | Organogel Canada Ltee | Implantable polymer hydrogel for therapeutic uses |
EP1024176A1 (de) * | 1998-08-13 | 2000-08-02 | Nippon Shokubai Co., Ltd. | Wasserquellbare vernetzte polymerzusammensetzung und verfahren zu deren herstellung |
Non-Patent Citations (1)
Title |
---|
See also references of WO02071994A1 * |
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP1372553A4 (de) | Hydrogele, die als reaktion auf veränderungen in der umgebung einer volumetrischen expansion unterzogen werden und ihre herstellungs- und verwendungsmethoden | |
GB0515801D0 (en) | Time in databases and applications of databases | |
AU2002350289A1 (en) | Polysaccharide biomaterials and methods of use thereof | |
ZA200305825B (en) | Modified antibodies and methods of use | |
AU2002310268A1 (en) | Synchronization of multiple simulation domains in an eda simulation environment | |
AU2002306768A1 (en) | Expression profiles and methods of use | |
IL158499A (en) | Malononitrile compounds and their use in the manufacture of pesticide compositions | |
AU2002351239A8 (en) | Antibody to latent membrane proteins and uses thereof | |
IL164181A0 (en) | Anti-il-tif antibodies and methods of using in inflammation | |
GB0128361D0 (en) | Improvements in and relating to instruments | |
EP1476150A4 (de) | Carboxyfullerene und verwendungsverfahren dafür | |
EP1419263A4 (de) | Hefe-expressionssystem, verfahren zur herstellung von polypeptiden in hefe sowie damit in verbindung stehende zusammensetzungen | |
AU2003247351A1 (en) | Anti-acne compositions and methods of use | |
AU1334602A (en) | Osteopontin-coated surfaces and methods of use | |
AU2003214148A8 (en) | Use of context identifiers in cache memory | |
AU2002314887A1 (en) | Gads as modifiers of the p53 pathway and methods of use | |
EP1649037A4 (de) | Immobilisierung von oligonukleotiden und proteinen in zuckerhaltigen hydrogelen | |
GB0222328D0 (en) | Improvements in and relating to the control of instruments | |
AU2003286600A8 (en) | Prkcb1 as modifier of branching morphogenesis and methods of use | |
AU2003276844A8 (en) | Formulations of modified antibodies and methods of making the same | |
EP1633850A4 (de) | Ovr115-antikörperzusammensetzung und verwendungsverfahren | |
AU2002352696A8 (en) | Cell substrates and methods of use thereof | |
GB0313617D0 (en) | Transparent conducting structures and methods of production | |
GB0105273D0 (en) | Improvements in or relating to assessment of fertility | |
EP1414427A4 (de) | Kavalacton-zusammensetzungen und anwendungsverfahren |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20030910 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR |
|
AX | Request for extension of the european patent |
Extension state: AL LT LV MK RO SI |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20060301 |
|
17Q | First examination report despatched |
Effective date: 20081024 |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: MICROVENTION, INC. |
|
GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
|
INTG | Intention to grant announced |
Effective date: 20140107 |
|
GRAS | Grant fee paid |
Free format text: ORIGINAL CODE: EPIDOSNIGR3 |
|
GRAA | (expected) grant |
Free format text: ORIGINAL CODE: 0009210 |
|
AK | Designated contracting states |
Kind code of ref document: B1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR |
|
REG | Reference to a national code |
Ref country code: GB Ref legal event code: FG4D |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: EP |
|
REG | Reference to a national code |
Ref country code: AT Ref legal event code: REF Ref document number: 674124 Country of ref document: AT Kind code of ref document: T Effective date: 20140715 |
|
REG | Reference to a national code |
Ref country code: IE Ref legal event code: FG4D |
|
REG | Reference to a national code |
Ref country code: ES Ref legal event code: FG2A Ref document number: 2478992 Country of ref document: ES Kind code of ref document: T3 Effective date: 20140723 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R096 Ref document number: 60246385 Country of ref document: DE Effective date: 20140807 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: FI Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20140625 Ref country code: CY Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20140625 Ref country code: GR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20140926 |
|
REG | Reference to a national code |
Ref country code: AT Ref legal event code: MK05 Ref document number: 674124 Country of ref document: AT Kind code of ref document: T Effective date: 20140625 |
|
REG | Reference to a national code |
Ref country code: NL Ref legal event code: VDEP Effective date: 20140625 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20140625 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: PT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20141027 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: AT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20140625 Ref country code: NL Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20140625 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R097 Ref document number: 60246385 Country of ref document: DE |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: DK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20140625 |
|
PLBE | No opposition filed within time limit |
Free format text: ORIGINAL CODE: 0009261 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT |
|
26N | No opposition filed |
Effective date: 20150326 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: BE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20140625 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LU Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20150228 |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: PL |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LI Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20150228 Ref country code: CH Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20150228 Ref country code: MC Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20140625 |
|
REG | Reference to a national code |
Ref country code: IE Ref legal event code: MM4A |
|
REG | Reference to a national code |
Ref country code: FR Ref legal event code: PLFP Year of fee payment: 15 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20150228 |
|
REG | Reference to a national code |
Ref country code: FR Ref legal event code: PLFP Year of fee payment: 16 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: IT Payment date: 20170221 Year of fee payment: 16 Ref country code: ES Payment date: 20170110 Year of fee payment: 16 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: TR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20140625 |
|
REG | Reference to a national code |
Ref country code: FR Ref legal event code: PLFP Year of fee payment: 17 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IT Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20180228 |
|
REG | Reference to a national code |
Ref country code: ES Ref legal event code: FD2A Effective date: 20190801 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: ES Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20180301 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: FR Payment date: 20210113 Year of fee payment: 20 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: DE Payment date: 20210216 Year of fee payment: 20 Ref country code: GB Payment date: 20210217 Year of fee payment: 20 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R071 Ref document number: 60246385 Country of ref document: DE |
|
REG | Reference to a national code |
Ref country code: GB Ref legal event code: PE20 Expiry date: 20220227 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: GB Free format text: LAPSE BECAUSE OF EXPIRATION OF PROTECTION Effective date: 20220227 |