PL335974A1 - Method of orally administering proteins - Google Patents

Method of orally administering proteins

Info

Publication number
PL335974A1
PL335974A1 PL98335974A PL33597498A PL335974A1 PL 335974 A1 PL335974 A1 PL 335974A1 PL 98335974 A PL98335974 A PL 98335974A PL 33597498 A PL33597498 A PL 33597498A PL 335974 A1 PL335974 A1 PL 335974A1
Authority
PL
Poland
Prior art keywords
orally administering
administering proteins
proteins
orally
administering
Prior art date
Application number
PL98335974A
Inventor
Nicholas A Peppas
Anthony M Lowman
Tsuneji Nagai
Mariko Morishita
Original Assignee
Purdue Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purdue Research Foundation filed Critical Purdue Research Foundation
Publication of PL335974A1 publication Critical patent/PL335974A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
PL98335974A 1997-04-02 1998-04-02 Method of orally administering proteins PL335974A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4228097P 1997-04-02 1997-04-02
US6136797P 1997-10-08 1997-10-08

Publications (1)

Publication Number Publication Date
PL335974A1 true PL335974A1 (en) 2000-06-05

Family

ID=26719055

Family Applications (1)

Application Number Title Priority Date Filing Date
PL98335974A PL335974A1 (en) 1997-04-02 1998-04-02 Method of orally administering proteins

Country Status (14)

Country Link
EP (1) EP0975328A1 (en)
JP (1) JP2002512607A (en)
KR (1) KR20010005952A (en)
CN (1) CN1259045A (en)
AU (1) AU727053B2 (en)
BR (1) BR9808466A (en)
CA (1) CA2285457A1 (en)
IL (1) IL132176A0 (en)
NO (1) NO994757L (en)
NZ (1) NZ500075A (en)
PL (1) PL335974A1 (en)
TR (1) TR199903240T2 (en)
WO (1) WO1998043615A1 (en)
YU (1) YU49699A (en)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
DE10040592A1 (en) * 2000-08-15 2002-03-07 Aventis Res & Tech Gmbh & Co Composition for oral administration of drugs, e.g. peptidomimetics or sparingly soluble antibiotics, containing hydrogel copolymer of unsaturated acid and polyalkylene glycol ester as resorption improver
US6878384B2 (en) 2001-03-13 2005-04-12 Microvention, Inc. Hydrogels that undergo volumetric expansion in response to changes in their environment and their methods of manufacture and use
EP1494732B1 (en) 2002-03-20 2008-01-30 MannKind Corporation Inhalation apparatus
KR101273120B1 (en) 2004-08-20 2013-06-13 맨카인드 코포레이션 Catalysis of diketopiperazine synthesis
KR20130066695A (en) 2004-08-23 2013-06-20 맨카인드 코포레이션 Diketopiperazine salts, diketomorpholine salts or diketodioxane salts for drug delivery
US8110212B2 (en) 2005-04-07 2012-02-07 Drexel University Bioactive thermogelling polymer systems and methods of their use
EP1916995B2 (en) 2005-07-29 2022-06-29 Stichting Groningen Centre for Drug Research Ph-controlled pulsatile delivery system, methods for preparation and use thereof
WO2007016600A2 (en) * 2005-08-01 2007-02-08 Mannkind Corporation Method of preserving the function of insulin-producing cells
IN2014DN09128A (en) 2005-09-14 2015-07-10 Mannkind Corp
BRPI0707991B8 (en) 2006-02-22 2021-05-25 Mannkind Corp methods of preparing a dry powder medicine with an improved pharmaceutical property, said dry powder and using an effective amount of the dry powder
EP2389960B1 (en) 2006-06-15 2018-02-28 MicroVention, Inc. Environmentally responsive hydrogel
US8470035B2 (en) 2007-12-21 2013-06-25 Microvention, Inc. Hydrogel filaments for biomedical uses
CN109568740B (en) 2008-06-13 2022-05-27 曼金德公司 Dry powder inhaler and system for drug delivery
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
ES2904623T3 (en) 2008-06-20 2022-04-05 Mannkind Corp Interactive device to establish a real-time profile of inhalation efforts
TWI494123B (en) 2008-08-11 2015-08-01 Mannkind Corp Use of ultrarapid acting insulin
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
PL2405963T3 (en) 2009-03-11 2014-04-30 Mannkind Corp Apparatus, system and method for measuring resistance of an inhaler
US10639396B2 (en) 2015-06-11 2020-05-05 Microvention, Inc. Polymers
KR101875969B1 (en) 2009-06-12 2018-07-06 맨카인드 코포레이션 Diketopiperazine microparticles with defined specific surface areas
HUP0900482A2 (en) 2009-08-03 2011-03-28 Cera Med Kft Pharmaceutical formulation for oral administration
KR20120090052A (en) 2009-09-24 2012-08-16 마이크로벤션, 인코포레이티드 Injectable hydrogel filaments for biomedical uses
JP5722333B2 (en) 2009-10-26 2015-05-20 マイクロベンション インコーポレイテッド Embolization device composed of expandable polymer
EP2496295A1 (en) 2009-11-03 2012-09-12 MannKind Corporation An apparatus and method for simulating inhalation efforts
KR20130117755A (en) 2010-06-21 2013-10-28 맨카인드 코포레이션 Dry powder drug delivery system and methods
JP6133270B2 (en) 2011-04-01 2017-05-24 マンカインド コーポレイション Blister packaging for drug cartridge
US9456823B2 (en) 2011-04-18 2016-10-04 Terumo Corporation Embolic devices
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
BR112014009686A2 (en) 2011-10-24 2018-08-07 Mannkind Corp Inhalable analgesic composition, dry powder and method for treating pain
US9011884B2 (en) 2012-04-18 2015-04-21 Microvention, Inc. Embolic devices
AU2013289957B2 (en) 2012-07-12 2017-02-23 Mannkind Corporation Dry powder drug delivery systems and methods
EP2911690A1 (en) 2012-10-26 2015-09-02 MannKind Corporation Inhalable influenza vaccine compositions and methods
ES2754388T3 (en) 2013-03-15 2020-04-17 Mannkind Corp Compositions and methods of microcrystalline dicetopiperazine
BR122019026637B1 (en) 2013-07-18 2023-09-26 Mannkind Corporation PHARMACEUTICAL DRY POWDER FORMULATIONS AND METHOD FOR MANUFACTURING A DRY POWDER FORMULATION
WO2015021044A1 (en) * 2013-08-05 2015-02-12 University Of Rochester Compositions and methods for stimuli-responsive release of a therapeutic agent
WO2015021064A1 (en) 2013-08-05 2015-02-12 Mannkind Corporation Insufflation apparatus and methods
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10124090B2 (en) 2014-04-03 2018-11-13 Terumo Corporation Embolic devices
WO2015167751A1 (en) 2014-04-29 2015-11-05 Microvention, Inc. Polymers
CN110433326A (en) 2014-04-29 2019-11-12 微仙美国有限公司 Polymer comprising activating agent
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
US10265405B2 (en) 2014-11-18 2019-04-23 Board Of Regents, The University Of Texas System Polymers for delivery of factor VIII and/or factor IX
WO2024130101A1 (en) * 2022-12-16 2024-06-20 Wake Forest University Health Sciences Hydrogel compositions and methods of making and using the same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2976576A (en) * 1956-04-24 1961-03-28 Wichterle Otto Process for producing shaped articles from three-dimensional hydrophilic high polymers
US3220960A (en) * 1960-12-21 1965-11-30 Wichterle Otto Cross-linked hydrophilic polymers and articles made therefrom
DE1617393C2 (en) * 1966-01-06 1982-11-11 Československá akademie věd, Praha Process for the preparation of hydrophilic crosslinked copolymers containing biologically active substances
US3607848A (en) * 1967-08-07 1971-09-21 Ceskoslovenska Akademie Ved Method for preparing insoluble,cross-linked organic hydrogels comprising copolymers of glycol monoesters with diesters
US3885078A (en) * 1968-03-06 1975-05-20 Ceskoslovenska Akademie Ved Hydrogel laminates and method of manufacturing thereof
US4071508A (en) * 1975-02-11 1978-01-31 Plastomedical Sciences, Inc. Anionic hydrogels based on hydroxyalkyl acrylates and methacrylates
FR2601026B1 (en) * 1986-04-15 1988-09-16 Rhone Poulenc Chimie DRY MATERIAL MOISTURIZABLE IN AN AQUEOUS GEL CONTAINING PARTICLES OF DISPERSE POLYMERS, METHOD FOR ITS PREPARATION AND ITS APPLICATION IN BIOLOGY

Also Published As

Publication number Publication date
NO994757D0 (en) 1999-09-30
NO994757L (en) 1999-11-29
AU727053B2 (en) 2000-11-30
CN1259045A (en) 2000-07-05
CA2285457A1 (en) 1998-10-08
YU49699A (en) 2002-12-10
JP2002512607A (en) 2002-04-23
NZ500075A (en) 2001-03-30
IL132176A0 (en) 2001-03-19
BR9808466A (en) 2001-08-07
AU6880998A (en) 1998-10-22
TR199903240T2 (en) 2000-05-22
KR20010005952A (en) 2001-01-15
WO1998043615A1 (en) 1998-10-08
EP0975328A1 (en) 2000-02-02

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