EE200000052A - 1,2,4-triasolo[4,3-b]pürido[3,2-d]püridasiini derivaadid, nende valmistamismeetod ja farmatseutiline kompositsioon ning nende kasutamine - Google Patents

1,2,4-triasolo[4,3-b]pürido[3,2-d]püridasiini derivaadid, nende valmistamismeetod ja farmatseutiline kompositsioon ning nende kasutamine

Info

Publication number
EE200000052A
EE200000052A EEP200000052A EEP200000052A EE200000052A EE 200000052 A EE200000052 A EE 200000052A EE P200000052 A EEP200000052 A EE P200000052A EE P200000052 A EEP200000052 A EE P200000052A EE 200000052 A EE200000052 A EE 200000052A
Authority
EE
Estonia
Prior art keywords
triazolo
pyrido
preparation
pharmaceutical composition
pyridazine derivatives
Prior art date
Application number
EEP200000052A
Other languages
English (en)
Inventor
Gracia Ferrer Jordi
Isabel Crespo Crespo Ma
Vega Noverola Armando
Fernandez Garcia Andr�s
Original Assignee
Almirall Prodesfarma S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Almirall Prodesfarma S.A. filed Critical Almirall Prodesfarma S.A.
Publication of EE200000052A publication Critical patent/EE200000052A/et
Publication of EE04313B1 publication Critical patent/EE04313B1/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
EEP200000052A 1997-07-29 1998-07-13 1,2,4-triasolo[4,3-b]pürido[3,2-d]püridasiini derivaadid, nende valmistamismeetod ja farmatseutiline kompositsioon ning nende kasutamine EE04313B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES009701670A ES2137113B1 (es) 1997-07-29 1997-07-29 Nuevos derivados de triazolo-piridazinas heterociclicos.
PCT/EP1998/004340 WO1999006404A1 (en) 1997-07-29 1998-07-13 1,2,4-triazolo[4,3-b]pyrido[3,2-d]pyridazine derivatives and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
EE200000052A true EE200000052A (et) 2000-10-16
EE04313B1 EE04313B1 (et) 2004-06-15

Family

ID=8300216

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200000052A EE04313B1 (et) 1997-07-29 1998-07-13 1,2,4-triasolo[4,3-b]pürido[3,2-d]püridasiini derivaadid, nende valmistamismeetod ja farmatseutiline kompositsioon ning nende kasutamine

Country Status (36)

Country Link
US (2) US6407108B1 (et)
EP (1) EP1001955B1 (et)
JP (1) JP4320118B2 (et)
KR (1) KR20010022353A (et)
CN (1) CN1135231C (et)
AR (1) AR015927A1 (et)
AT (1) ATE207069T1 (et)
AU (1) AU737709B2 (et)
BG (1) BG64448B1 (et)
BR (1) BR9810829B1 (et)
CA (1) CA2298935A1 (et)
CO (1) CO4970780A1 (et)
CZ (1) CZ290208B6 (et)
DE (1) DE69802100T2 (et)
DK (1) DK1001955T3 (et)
EE (1) EE04313B1 (et)
EG (1) EG24041A (et)
ES (2) ES2137113B1 (et)
HK (1) HK1024914A1 (et)
HU (1) HUP0004708A3 (et)
ID (1) ID24506A (et)
IL (1) IL134081A (et)
MY (1) MY118796A (et)
NO (1) NO315118B1 (et)
NZ (1) NZ502356A (et)
PE (1) PE111099A1 (et)
PL (1) PL191031B1 (et)
PT (1) PT1001955E (et)
RU (1) RU2202552C2 (et)
SI (1) SI1001955T1 (et)
SK (1) SK284046B6 (et)
TR (1) TR200000243T2 (et)
TW (1) TW542837B (et)
UA (1) UA60339C2 (et)
WO (1) WO1999006404A1 (et)
ZA (1) ZA986248B (et)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2792938B1 (fr) * 1999-04-28 2001-07-06 Warner Lambert Co NOUVELLES 1-AMINO TRIAZOLO [4,3-a] QUINAZOLINE-5-ONES INHIBITRICES DE PHOSPHODIESTERASES IV
JP5038568B2 (ja) 1999-08-21 2012-10-03 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 協力剤の組合せ物
WO2002080974A1 (fr) * 2001-04-04 2002-10-17 Sankyo Company, Limited Utilisation medicale d'inhibiteur de production de cytokine
US20040242597A1 (en) * 2001-09-19 2004-12-02 Thomas Klein Combination
FR2832711B1 (fr) * 2001-11-26 2004-01-30 Warner Lambert Co Derives de triazolo [4,3-a] pyrido [2,3-d] pyrimidin-5-ones, compositions les contenant, procede de preparation et utilisation
JP4700965B2 (ja) * 2002-11-06 2011-06-15 あすか製薬株式会社 ピラゾロナフチリジン誘導体
ES2211344B1 (es) 2002-12-26 2005-10-01 Almirall Prodesfarma, S.A. Nuevos derivados de piridazin-3(2h)-ona.
US20050187278A1 (en) * 2003-08-28 2005-08-25 Pharmacia Corporation Treatment or prevention of vascular disorders with Cox-2 inhibitors in combination with cyclic AMP-specific phosphodiesterase inhibitors
RU2246496C1 (ru) * 2003-09-12 2005-02-20 Тец Виктор Вениаминович Вещество с противовирусной и антибактериальной активностью на основе производных 2,8-дитиоксо-1h-пирано[2,3-d, 6,5-d`] дипиримидина и их 10-аза-аналогов
ES2251866B1 (es) 2004-06-18 2007-06-16 Laboratorios Almirall S.A. Nuevos derivados de piridazin-3(2h)-ona.
PT1898903E (pt) * 2005-06-10 2013-06-28 Merck Sharp & Dohme Inibidores da atividade de akt
JP2009506069A (ja) 2005-08-26 2009-02-12 ブレインセルス，インコーポレイティド ムスカリン性受容体調節による神経発生
EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
CN101268073B (zh) 2005-09-15 2011-10-19 Aska制药株式会社 杂环化合物、制备方法及其用途
AU2006304787A1 (en) 2005-10-21 2007-04-26 Braincells, Inc. Modulation of neurogenesis by PDE inhibition
CA2625210A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
EP2377531A2 (en) 2006-05-09 2011-10-19 Braincells, Inc. Neurogenesis by modulating angiotensin
EP2026813A2 (en) 2006-05-09 2009-02-25 Braincells, Inc. 5 ht receptor mediated neurogenesis
WO2008021781A1 (en) 2006-08-07 2008-02-21 Incyte Corporation Triazolotriazines as kinase inhibitors
US7998971B2 (en) 2006-09-08 2011-08-16 Braincells Inc. Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
ES2689444T3 (es) 2006-11-22 2018-11-14 Incyte Holdings Corporation Imidazotriazinas e imidazopirimidinas como inhibidores de la quinasa
WO2009089027A1 (en) * 2008-01-09 2009-07-16 Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Service, National Institutes Of Health Phosphodiesterase inhibitors
SI2300455T1 (sl) 2008-05-21 2017-12-29 Incyte Holdings Corporation Soli 2-fluoro-n-metil-4-(7-(kinolin-6-il-metil)-imidazo(1,2-b)1,2,4) triazin-2-il)benzamid in postopki v zvezi z njihovo pripravo
EP2196465A1 (en) 2008-12-15 2010-06-16 Almirall, S.A. (3-oxo)pyridazin-4-ylurea derivatives as PDE4 inhibitors
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
EP2226323A1 (en) 2009-02-27 2010-09-08 Almirall, S.A. New tetrahydropyrazolo[3,4-c]isoquinolin-5-amine derivatives
SG182297A1 (en) 2009-12-31 2012-08-30 Ct Nac Investigaciones Oncologicas Cnio Tricyclic compounds for use as kinase inhibitors
BR112012019302B1 (pt) 2010-02-03 2022-06-21 Incyte Holdings Corporation Imidazo[1,2-b] [1,2,4]triazinas como inibidores de c-met, composição que as compreende e métodos in vitro de inibir a atividade de c-met cinase, de inibir a via de sinalização da hgf/c-met cinase em uma célula e de inibir a atividade proliferativa de uma célula
EP2380890A1 (en) 2010-04-23 2011-10-26 Almirall, S.A. New 7,8-dihydro-1,6-naphthyridin-5(6h)-one-derivatives as PDE4 inhibitors
EP2394998A1 (en) 2010-05-31 2011-12-14 Almirall, S.A. 3-(5-Amino-6-oxo-1,6-dihydropyridazin-3-yl)-biphenyl derivatives as PDE4 inhibitors
WO2012098387A1 (en) 2011-01-18 2012-07-26 Centro Nacional De Investigaciones Oncológicas (Cnio) 6, 7-ring-fused triazolo [4, 3 - b] pyridazine derivatives as pim inhibitors
WO2013004984A1 (en) 2011-07-07 2013-01-10 Centro Nacional De Investigaciones Oncologicas (Cnio) Tricyclic compounds for use as kinase inhibitors
WO2013005057A1 (en) 2011-07-07 2013-01-10 Centro Nacional De Investigaciones Oncológicas (Cnio) New compounds
WO2013005041A1 (en) 2011-07-07 2013-01-10 Centro Nacional De Investigaciones Oncológicas (Cnio) Tricyclic heterocyclic compounds as kinase inhibitors
EP2804603A1 (en) 2012-01-10 2014-11-26 President and Fellows of Harvard College Beta-cell replication promoting compounds and methods of their use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3122670A1 (de) 1981-06-06 1982-12-23 Dr. Karl Thomae Gmbh, 7950 Biberach "neue 1,4,9,10-tetrahydro-pyrazolo(4,3-e) pyrido(3,2-b)(1,4)diazepin-10-one, verfahren zu ihrer herstellung und ihre verwendung zur herstellung von pharmazeutischen wirkstoffen"
FI81350C (fi) * 1982-01-18 1990-10-10 Lepetit Spa Analogfoerfarande foer framstaellning av nya, farmakologiskt aktiva 6-substituerade s-triatsolo/3,4-a/ ftalazinderivat.
JP3120857B2 (ja) * 1990-02-19 2000-12-25 中外製薬株式会社 新規な縮合複素環化合物とこれを用いた抗喘息剤
HUT66969A (en) * 1991-10-09 1995-01-30 Syntex Inc Benzo- and pyrido-pyridazinone- and pyridazin-thion derivatives, pharmaceutical compositions containing the same and process for the production of thereof
GB9514465D0 (en) 1995-07-14 1995-09-13 Glaxo Lab Sa Chemical compounds

Also Published As

Publication number Publication date
IL134081A (en) 2004-02-08
WO1999006404A1 (en) 1999-02-11
CZ2000333A3 (cs) 2000-05-17
ATE207069T1 (de) 2001-11-15
HK1024914A1 (en) 2000-10-27
DK1001955T3 (da) 2001-11-19
BR9810829A (pt) 2000-07-25
TW542837B (en) 2003-07-21
CO4970780A1 (es) 2000-11-07
BG64448B1 (en) 2005-02-28
AU8861298A (en) 1999-02-22
RU2202552C2 (ru) 2003-04-20
JP4320118B2 (ja) 2009-08-26
ES2137113A1 (es) 1999-12-01
CA2298935A1 (en) 1999-02-11
CN1266434A (zh) 2000-09-13
CZ290208B6 (cs) 2002-06-12
HUP0004708A3 (en) 2002-11-28
NO315118B1 (no) 2003-07-14
AR015927A1 (es) 2001-05-30
EE04313B1 (et) 2004-06-15
AU737709B2 (en) 2001-08-30
PL191031B1 (pl) 2006-03-31
PE111099A1 (es) 1999-11-18
US20020183326A1 (en) 2002-12-05
SK862000A3 (en) 2000-07-11
EP1001955A1 (en) 2000-05-24
EG24041A (en) 2008-04-03
ES2162466T3 (es) 2001-12-16
DE69802100D1 (de) 2001-11-22
IL134081A0 (en) 2001-04-30
ZA986248B (en) 1999-02-05
EP1001955B1 (en) 2001-10-17
NO20000394D0 (no) 2000-01-26
NO20000394L (no) 2000-03-27
NZ502356A (en) 2001-03-30
JP2001512121A (ja) 2001-08-21
KR20010022353A (ko) 2001-03-15
UA60339C2 (uk) 2003-10-15
US6407108B1 (en) 2002-06-18
BG104112A (en) 2001-01-31
PT1001955E (pt) 2002-02-28
PL338214A1 (en) 2000-10-09
HUP0004708A2 (hu) 2001-07-30
ES2137113B1 (es) 2000-09-16
SI1001955T1 (en) 2002-02-28
ID24506A (id) 2000-07-20
BR9810829B1 (pt) 2009-08-11
TR200000243T2 (tr) 2000-07-21
SK284046B6 (sk) 2004-08-03
DE69802100T2 (de) 2002-03-14
MY118796A (en) 2005-01-31
CN1135231C (zh) 2004-01-21

Similar Documents

Publication Publication Date Title
EE200000052A (et) 1,2,4-triasolo[4,3-b]pürido[3,2-d]püridasiini derivaadid, nende valmistamismeetod ja farmatseutiline kompositsioon ning nende kasutamine
HUP0202494A2 (en) Imidazo[1,2-a]pyridine and pyrazolo[2,3-a]pyridine derivatives, process for their preparation and pharmaceutical compositions containing them
HUP0105081A3 (en) Triazolo[4,5-d]pyrimidine derivatives, process for their preparation, their use and pharmaceutical compositions containing them
HUP0100202A3 (en) Novel triazolo[4,5-d]pyrimidine derivatives, process for their preparation, their use and pharmaceutical compositions containing them
HUP0001805A3 (en) 6-benzyl-1,5-dihydro-pyrazolo[3,4-d]-pyrimidin-4-one derivatives, process for their preparation and pharmaceutical compositions containing them
HUP0004333A3 (en) Novel triazolo [4,5-d] pyrimidine derivatives, process for their preparation and pharmaceutical compositions containing thereof
HUP0000720A3 (en) Imidazo [1,2-a] pyridine derivatives, process for their preparation, pharmaceutical formulation containing them and their use
HUP0003826A3 (en) Novel triazolo [4,5-b] pyrimidine derivatives, process for their preparation and pharmaceutical compositions thereof
HUP9801602A3 (en) Imidazo[1,2-a]pyridine derivatives, process for their production, pharmaceutical compositions and use thereof
HUP0001507A3 (en) Pyrrolo [2,3-d] pyrimidine derivatives, process for their preparation, their use and pharmaceutical compositions containing them
HUP0200450A3 (en) Cephen derivatives containing an imidazo[4,5-b]pyridiniummethyl moiety, process for their preparation and pharmaceutical compositions of the same
HUP0002104A3 (en) Pyrazolo[3,4-d]pyrimidinedione derivatives, process for their preparation and pharmaceutical compositions containing them
HUP0002839A3 (en) Pyrrolo[3,4-d]pyrimidinone derivatives, their use, pharmaceutical compositions containing them, process for their preparation
HUP0001922A3 (en) Pyrazolo[4,3-c]-pyridine derivatives, pharmaceutical compositions thereof against insulin resistance, intermediates and process for their preparation
CZ2019997A3 (cs) Deriváty pyridazino [4,5-B] chinolin-5-oxidu, způsob jejich přípravy a jejich použití jako antagonistů glycinu
PL307328A1 (en) Novel derivatives of imidazo [1,2-a] pyridine and method of obtaining them as well as pharmaceutical preparation and method of preparing same
HUP9904107A3 (en) 3-substituted pyrido[4',3':4,5]thieno[2,3-d]pyrimidine derivatives,their preparation and their use
HUP0102117A2 (hu) Imidazo[1,2-a]piridin-származékok és ezeket tartalmazó gyógyászati készítmények
EE9900155A (et) 1H-pürido[3,4-b]indool-4-karboksamiidi derivaadid, nende valmistamismeetod ja kasutamine raviks
HUP0105132A3 (en) Process for preparing imidazo[1,5-a]-pyrido[3,2-e]-pyrazinones and the use of the same for preparing pharmaceutical compositions
HUP0105054A3 (en) Imidazo[4,5-c]-pyridine-4-on-derivatives, pharmaceutical compositions containing them and process for their preparation
HUP9901038A3 (en) Pyrido[2,3-b]pyrazine derivatives, pharmaceutical compositions containing these compounds, process for the preparation and use of the ingredients and compositions
HUP0003394A3 (en) Pyrido[2,3-b][1,5]benzodiazepine derivatives, their use, process for their preparation and pharmaceutical compositions containing them
HU0003979D0 (en) Process for the preparation of 3-pyridylsulphonil-pyrazolo[4,3-d] pyrimidin-7-one derivatives and intermediates thereof
HUP0002736A3 (en) 3-substituted pyrido [3',4':4,5]thieno[2,3-d]pyrimidine derivatives, and their use for the preparation of pharmaceutical compositions

Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20041231

KB4A Valid patent at the end of a year

Effective date: 20051231

KB4A Valid patent at the end of a year

Effective date: 20061231

KB4A Valid patent at the end of a year

Effective date: 20071231

KB4A Valid patent at the end of a year

Effective date: 20081231

KB4A Valid patent at the end of a year

Effective date: 20101231

MM4A Lapsed by not paying the annual fees

Effective date: 20100713