EE05183B1 - Asabitsklilised hendid, nende valmistamine ja kasutamine ravimitena ning neid sisaldav farmatseutiline kompositsioon - Google Patents
Asabitsklilised hendid, nende valmistamine ja kasutamine ravimitena ning neid sisaldav farmatseutiline kompositsioonInfo
- Publication number
- EE05183B1 EE05183B1 EEP200300046A EEP200300046A EE05183B1 EE 05183 B1 EE05183 B1 EE 05183B1 EE P200300046 A EEP200300046 A EE P200300046A EE P200300046 A EEP200300046 A EE P200300046A EE 05183 B1 EE05183 B1 EE 05183B1
- Authority
- EE
- Estonia
- Prior art keywords
- azabitic
- pharmaceuticals
- compounds
- preparation
- pharmaceutical composition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0010121A FR2812635B1 (fr) | 2000-08-01 | 2000-08-01 | Nouveaux composes heterocycliques, preparation et utilisation comme medicaments notamment comme anti- bacteriens |
| PCT/FR2001/002418 WO2002010172A1 (fr) | 2000-08-01 | 2001-07-24 | Composes azabicycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EE200300046A EE200300046A (et) | 2004-10-15 |
| EE05183B1 true EE05183B1 (et) | 2009-06-15 |
Family
ID=8853181
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EEP200300046A EE05183B1 (et) | 2000-08-01 | 2001-07-24 | Asabitsklilised hendid, nende valmistamine ja kasutamine ravimitena ning neid sisaldav farmatseutiline kompositsioon |
Country Status (42)
| Country | Link |
|---|---|
| US (5) | US7112592B2 (et) |
| EP (1) | EP1307457B1 (et) |
| JP (2) | JP4515704B2 (et) |
| KR (1) | KR100632906B1 (et) |
| CN (1) | CN1289500C (et) |
| AP (1) | AP1614A (et) |
| AR (1) | AR031716A1 (et) |
| AT (1) | ATE263768T1 (et) |
| AU (2) | AU7990501A (et) |
| BG (1) | BG66094B1 (et) |
| BR (1) | BRPI0112986B8 (et) |
| CA (1) | CA2417475C (et) |
| CR (1) | CR6895A (et) |
| CZ (1) | CZ294956B6 (et) |
| DE (1) | DE60102702T2 (et) |
| DK (1) | DK1307457T3 (et) |
| DZ (1) | DZ3397A1 (et) |
| EA (1) | EA004920B1 (et) |
| EC (1) | ECSP034460A (et) |
| EE (1) | EE05183B1 (et) |
| ES (1) | ES2220793T3 (et) |
| FR (1) | FR2812635B1 (et) |
| HK (1) | HK1060356A1 (et) |
| HR (1) | HRP20030034B1 (et) |
| HU (1) | HU226889B1 (et) |
| IL (2) | IL154187A0 (et) |
| MA (1) | MA26938A1 (et) |
| ME (2) | MEP17108A (et) |
| MX (1) | MXPA03000881A (et) |
| NO (1) | NO324940B1 (et) |
| NZ (1) | NZ523707A (et) |
| OA (1) | OA12347A (et) |
| PL (2) | PL216028B1 (et) |
| PT (1) | PT1307457E (et) |
| RS (1) | RS50214B (et) |
| SI (1) | SI1307457T1 (et) |
| SK (1) | SK287597B6 (et) |
| TR (1) | TR200400859T4 (et) |
| TW (1) | TWI292401B (et) |
| UA (1) | UA73791C2 (et) |
| WO (1) | WO2002010172A1 (et) |
| ZA (1) | ZA200300676B (et) |
Families Citing this family (95)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2812635B1 (fr) * | 2000-08-01 | 2002-10-11 | Aventis Pharma Sa | Nouveaux composes heterocycliques, preparation et utilisation comme medicaments notamment comme anti- bacteriens |
| FR2835186B1 (fr) * | 2002-01-28 | 2006-10-20 | Aventis Pharma Sa | Nouveaux composes heterocycliques, actifs comme inhibiteurs de beta-lactamases |
| FR2844273B1 (fr) * | 2002-09-05 | 2008-04-04 | Aventis Pharma Sa | Nouveaux composes heterocycliques, procede et intermediaires de preparation et utilisation comme medicament, notamment comme inhibiteurs de beta-lactamases et anti-bacteriens. |
| US7439253B2 (en) * | 2002-12-06 | 2008-10-21 | Novexel | Heterocyclic compounds, their preparation and their use as medicaments, in particular as antibacterials and beta-lactamase inhibitors |
| FR2848210B1 (fr) * | 2002-12-06 | 2007-10-19 | Aventis Pharma Sa | Nouveaux composes heterocycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens et inhibiteurs de beta-lactamases |
| ES2373461T3 (es) | 2005-12-07 | 2012-02-03 | Basilea Pharmaceutica Ag | Antibióticos útiles de monobactama. |
| CA2657618C (en) | 2006-07-13 | 2016-10-11 | Achillion Pharmaceuticals, Inc. | 4-amino-4-oxobutanoyl peptides as inhibitors of viral replication |
| JP5539717B2 (ja) * | 2006-07-14 | 2014-07-02 | 塩野義製薬株式会社 | オキシム化合物およびその使用 |
| EP2069347A2 (en) * | 2006-09-27 | 2009-06-17 | Merck & Co., Inc. | Novel inhibitors of beta-lactamase |
| JP2010507681A (ja) * | 2006-10-23 | 2010-03-11 | アイアールエム・リミテッド・ライアビリティ・カンパニー | カテプシンプロテアーゼ阻害剤 |
| US20100056497A1 (en) | 2007-01-31 | 2010-03-04 | Dainippon Sumitomo Pharma Co., Ltd | Amide derivative |
| FR2914923B1 (fr) * | 2007-04-12 | 2013-06-14 | Novexel | Nouveaux composes heterocycliques azotes,leur preparation et leur utilisation comme medicaments antibacteriens. |
| ES2422603T3 (es) | 2007-05-31 | 2013-09-12 | Shionogi & Co | Compuestos oxiimino y el uso de estos |
| FR2921060B1 (fr) | 2007-09-14 | 2012-06-15 | Novexel | Nouveau procede de preparation d'une piperidine disubsituee et nouveaux intermediaires |
| PT2666774E (pt) * | 2008-01-18 | 2015-04-13 | Merck Sharp & Dohme | Inibidores de beta-lactamase |
| WO2009151152A1 (en) | 2008-06-11 | 2009-12-17 | Shionogi & Co., Ltd. | Oxycarbamoyl compounds and the use thereof |
| EP2135959A1 (en) | 2008-06-19 | 2009-12-23 | Novexel | Use of (1R,2S,5R) 1,6-Diazabicyclo [3,2,1]octane-2-carboxamide, 7-oxo-6-(sulfooxy)-, monosodium salt as a diagnostic reagent for detecting serine beta-lactamases |
| FR2936798B1 (fr) | 2008-10-03 | 2012-09-28 | Novexel | Nouveaux composes heterocycliques azotes, leur preparation et leur utilisation comme medicaments antibacteriens. |
| FR2937034B1 (fr) | 2008-10-10 | 2012-11-23 | Novexel | Nouveaux composes heterocycliques azotes, leur preparation et leur utilisation comme medicaments antibacteriens |
| US20120053350A1 (en) * | 2009-04-30 | 2012-03-01 | Ian Mangion | Preparation of alkyl esters of n-protected oxo-azacycloalkylcarboxylic acids |
| CN102482256B (zh) | 2009-06-24 | 2014-11-26 | 大日本住友制药株式会社 | N-取代的环状氨基衍生物 |
| FR2951171A1 (fr) | 2009-10-09 | 2011-04-15 | Novexel | Nouveau sel de sodium d'un compose azabicyclique sous forme enantiomere cristallisee et nouvelles formes polymorphes et pseudopolymorphes ainsi que leur preparation |
| KR101836554B1 (ko) * | 2010-12-22 | 2018-04-19 | 메이지 세이카 파루마 가부시키가이샤 | 광학 활성인 디아자비시클로옥탄 유도체 및 그의 제조법 |
| US8772490B2 (en) | 2010-12-22 | 2014-07-08 | Meiji Seika Pharma Co., Ltd. | Optically active diazabicyclooctane derivatives and process for preparing the same |
| MX361020B (es) * | 2011-06-17 | 2018-11-26 | Pfizer Anti Infectives Ab | Procesos para preparar compuestos heterociclicos, incluida trans-7-oxo-6-(sulfooxi)-1,6-diazabiciclo [3,2,1]octano-2-carboxam ida y sales de la misma. |
| PT2748165T (pt) * | 2011-08-27 | 2016-12-28 | Wockhardt Ltd | Derivados de 1,6-diazabiciclo[3,2,1]octano-7-ona e sua utilização no tratamento de infeções bacterianas |
| MX340533B (es) * | 2011-08-30 | 2016-07-13 | Wockhardt Ltd | Derivados de 1,6- diazabiciclo [3,2,1] octan-7-ona y su uso en el tratamiento de infecciones bacterianas. |
| US8969567B2 (en) | 2011-09-13 | 2015-03-03 | Wockhardt Ltd. | Nitrogen containing compounds and their use |
| CN103781787B (zh) | 2011-09-13 | 2015-09-23 | 沃克哈特有限公司 | 含氮化合物及其用途 |
| US8796257B2 (en) | 2011-12-02 | 2014-08-05 | Naeja Pharmaceutical Inc. | Bicyclic compounds and their use as antibacterial agents and β-lactamase inhibitors |
| US9505761B2 (en) | 2011-12-02 | 2016-11-29 | Fedora Pharmaceuticals Inc. | Bicyclic compounds and their use as antibacterial agents and beta-lactamase inhibitors |
| US8916709B2 (en) | 2012-03-30 | 2014-12-23 | Cubist Pharmaceuticals, Inc. | 1,2,4-oxadiazole and 1,2,4-thiadiazole β-lactamase inhibitors |
| KR20150003777A (ko) | 2012-03-30 | 2015-01-09 | 큐비스트 파마슈티컬즈 인코포레이티드 | 이속사졸 β-락타마제 억제제 |
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| RU2014143821A (ru) | 2012-03-30 | 2016-05-27 | Кьюбист Фармасьютикалз, Инк. | 1, 3, 4-ОКСАДИАЗОЛЬНЫЕ И 1, 3, 4-ТИАДИАЗОЛЬНЫЕ ИНГИБИТОРЫ β-ЛАКТАМАЗЫ |
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| AU2013308127B2 (en) * | 2012-08-25 | 2015-08-13 | Wockhardt Limited | 1,6- Diazabicyclo [3,2,1] octan- 7- one derivatives and their use in the treatment of bacterial infections |
| SG11201503427TA (en) | 2012-11-01 | 2015-06-29 | Kaneka Corp | Process for producing optically active bicyclic urea compound |
| UA111925C2 (uk) | 2012-12-11 | 2016-06-24 | Федора Фармасьютікалз Інк. | БІЦИКЛІЧНІ СПОЛУКИ ТА ЇХ ВИКОРИСТАННЯ ЯК АНТИБАКТЕРІАЛЬНИХ АГЕНТІВ ТА ІНГІБІТОРІВ β-ЛАКТАМАЗИ |
| JP6476110B2 (ja) | 2013-02-19 | 2019-02-27 | 株式会社エーピーアイ コーポレーション | Ｌ−リジン水酸化酵素およびそれを利用したヒドロキシ−ｌ−リジンの製造法およびヒドロキシ−ｌ−ピペコリン酸の製造法 |
| WO2014135930A1 (en) | 2013-03-08 | 2014-09-12 | Wockhardt Limited | A process for sodium salt of (2s, 5r)-2-carboxamido-7-oxo-6-sulfooxy -1,6-diaza-bicyclo[3.2.1]octane |
| CN105164132A (zh) * | 2013-03-08 | 2015-12-16 | 沃克哈特有限公司 | (2s,5r)-6-苄氧基-7-氧代-1,6-二氮杂-双环[3.2.1]辛烷-2-羧酸钠及其制备方法 |
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| WO2014200786A1 (en) * | 2013-06-10 | 2014-12-18 | Merck Sharp & Dohme Corp. | Preparation of tert-butyl 4-((1r,2s,5r)-6- (benzyloxy)-7-0x0-1,6-diazabicycl0[3.2.i]octane-2- carboxamido)piperidine-1-carboxylate |
| BR112016006246B8 (pt) | 2013-09-24 | 2021-10-05 | Meiji Seika Pharma Co Ltd | Processos de produção de derivados de diazabiciclo-octano e compostos intermediários dos mesmos |
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| US11565999B2 (en) | 2019-04-25 | 2023-01-31 | Arixa Pharmaceuticals, Inc. | Methods of synthesizing aztreonam derivatives |
| CN110078728B (zh) * | 2019-05-23 | 2020-10-23 | 江西富祥药业股份有限公司 | 一种阿维巴坦中间体、制备方法及其应用 |
| WO2021106864A1 (en) * | 2019-11-25 | 2021-06-03 | Eisai R&D Management Co., Ltd. | Process for the preparation of producing pyrazolo[1,5-a] pyrimidine derivatives |
| US11814385B2 (en) | 2021-06-25 | 2023-11-14 | University Of South Florida | Small molecule inhibitors targeting Clostridioides difficile sporulation |
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| JPS4939678B1 (et) * | 1968-05-06 | 1974-10-28 | ||
| US4024147A (en) * | 1972-06-30 | 1977-05-17 | John Wyeth & Brother Limited | Heterocyclic compounds |
| US4049821A (en) * | 1976-05-12 | 1977-09-20 | A. H. Robins Company, Inc. | Method of treating allergy |
| JPS63119471A (ja) * | 1986-09-02 | 1988-05-24 | ザ・ユニバーシテイ・オブ・メルボルン | ２−オキソ−４−カルボキシ−ピリミジン |
| EP0260057A3 (en) * | 1986-09-02 | 1989-02-01 | The University Of Melbourne | 2-oxo-4-carboxy-pyrimidines |
| BR9408450A (pt) * | 1993-12-29 | 1997-08-05 | Pfizer | Antagonistas da neuroquinina diazabiciclicos |
| TW358097B (en) * | 1996-05-24 | 1999-05-11 | Hoffmann La Roche | Beta-lactams and their process and pharmaceutical compositions |
| HUP0001741A3 (en) * | 1996-08-02 | 2000-11-28 | Smithkline Beecham Plc | Azabicyclic carbamoyloxy mutilin derivatives for antibacterial use, process for preparing them, pharmaceuticals contg. them and their use |
| YU35699A (sh) * | 1997-02-10 | 2002-06-19 | Pfizer Products Inc. | 2-amino-6-(2-supstituisan-4-fenoksi)-supstituisani piridini |
| US6060585A (en) * | 1997-03-04 | 2000-05-09 | Wisconsin Alumni Research Foundation | β-polypeptide foldamers of well-defined secondary structure |
| KR100207096B1 (ko) * | 1997-07-08 | 1999-07-15 | 이명환 | 시사프라이드의 제조 방법 |
| DE69906059D1 (de) * | 1998-04-20 | 2003-04-24 | Fujisawa Pharmaceutical Co | Anthranilsäurederivate als inhibitoren der c-gmp-phosphodiesterase |
| GB9817029D0 (en) * | 1998-08-05 | 1998-09-30 | Smithkline Beecham Plc | Novel compounds |
| FR2784682B1 (fr) * | 1998-10-15 | 2002-12-06 | Hoechst Marion Roussel Inc | Nouveaux derives 2-halogene de 5-0-desosaminylerythronolide a, leur procede de preparation et leur application comme medicaments |
| DE69919212T2 (de) * | 1998-12-23 | 2005-07-28 | Eli Lilly And Co., Indianapolis | Aromatische amiden |
| HUP0105437A3 (en) * | 1999-01-02 | 2003-03-28 | Aventis Pharma Gmbh | Novel malonic acid derivatives, processes for their preparation, their use and pharmaceutical compositions containing them |
| FR2812635B1 (fr) * | 2000-08-01 | 2002-10-11 | Aventis Pharma Sa | Nouveaux composes heterocycliques, preparation et utilisation comme medicaments notamment comme anti- bacteriens |
| FR2835186B1 (fr) * | 2002-01-28 | 2006-10-20 | Aventis Pharma Sa | Nouveaux composes heterocycliques, actifs comme inhibiteurs de beta-lactamases |
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