EE04751B1 - Tropaani derivaadid, nende valmistamine ja kasutamine - Google Patents

Tropaani derivaadid, nende valmistamine ja kasutamine

Info

Publication number
EE04751B1
EE04751B1 EE9800254A EE9800254A EE04751B1 EE 04751 B1 EE04751 B1 EE 04751B1 EE 9800254 A EE9800254 A EE 9800254A EE 9800254 A EE9800254 A EE 9800254A EE 04751 B1 EE04751 B1 EE 04751B1
Authority
EE
Estonia
Prior art keywords
disorders
derivatives
preparation
monoamine neurotransmitter
uptake
Prior art date
Application number
EE9800254A
Other languages
English (en)
Estonian (et)
Other versions
EE9800254A (et
Inventor
Scheel-Kr�ger J�rgen
Moldt Peter
W�tjen Frank
Original Assignee
Neurosearch A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch A/S filed Critical Neurosearch A/S
Publication of EE9800254A publication Critical patent/EE9800254A/xx
Publication of EE04751B1 publication Critical patent/EE04751B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
EE9800254A 1996-02-22 1997-02-21 Tropaani derivaadid, nende valmistamine ja kasutamine EE04751B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK19496 1996-02-22
PCT/EP1997/000850 WO1997030997A1 (en) 1996-02-22 1997-02-21 Tropane-derivatives, their preparation and use

Publications (2)

Publication Number Publication Date
EE9800254A EE9800254A (et) 1999-02-15
EE04751B1 true EE04751B1 (et) 2006-12-15

Family

ID=8090830

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9800254A EE04751B1 (et) 1996-02-22 1997-02-21 Tropaani derivaadid, nende valmistamine ja kasutamine

Country Status (32)

Country Link
US (3) US6288079B1 (cs)
EP (2) EP1130020A1 (cs)
JP (1) JP3238414B2 (cs)
KR (1) KR100446571B1 (cs)
CN (1) CN1077574C (cs)
AT (1) ATE203023T1 (cs)
AU (1) AU720358B2 (cs)
BG (1) BG63945B1 (cs)
BR (1) BR9707636A (cs)
CA (1) CA2244773C (cs)
CZ (1) CZ287007B6 (cs)
DE (1) DE69705608T2 (cs)
DK (1) DK0885220T3 (cs)
EE (1) EE04751B1 (cs)
ES (1) ES2159839T3 (cs)
GR (1) GR3036829T3 (cs)
HK (1) HK1018957A1 (cs)
HU (1) HU228356B1 (cs)
IL (1) IL125146A (cs)
IS (1) IS1824B (cs)
NO (1) NO318731B1 (cs)
NZ (1) NZ330886A (cs)
PL (1) PL185132B1 (cs)
PT (1) PT885220E (cs)
RU (1) RU2167876C2 (cs)
SG (1) SG99853A1 (cs)
SI (1) SI0885220T1 (cs)
SK (1) SK281813B6 (cs)
TR (1) TR199801641T2 (cs)
UA (1) UA49872C2 (cs)
WO (1) WO1997030997A1 (cs)
ZA (1) ZA971525B (cs)

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Also Published As

Publication number Publication date
HK1018957A1 (en) 2000-01-14
NO983877L (no) 1998-08-21
WO1997030997A1 (en) 1997-08-28
RU2167876C2 (ru) 2001-05-27
AU1794097A (en) 1997-09-10
KR100446571B1 (ko) 2004-11-03
CN1077574C (zh) 2002-01-09
EP0885220A1 (en) 1998-12-23
CA2244773A1 (en) 1997-08-28
PL328503A1 (en) 1999-02-01
TR199801641T2 (xx) 1998-11-23
IS1824B (is) 2002-10-01
HU228356B1 (en) 2013-03-28
US20010018444A1 (en) 2001-08-30
EP1130020A1 (en) 2001-09-05
ES2159839T3 (es) 2001-10-16
NO318731B1 (no) 2005-05-02
BG102637A (en) 1999-06-30
BG63945B1 (bg) 2003-07-31
HUP9901199A3 (en) 2001-02-28
SK92998A3 (en) 1998-11-04
CZ252098A3 (cs) 1998-11-11
GR3036829T3 (en) 2002-01-31
SI0885220T1 (en) 2001-12-31
CN1211982A (zh) 1999-03-24
EE9800254A (et) 1999-02-15
PT885220E (pt) 2001-11-30
US6395748B2 (en) 2002-05-28
AU720358B2 (en) 2000-06-01
DE69705608T2 (de) 2002-05-16
KR19990087127A (ko) 1999-12-15
IL125146A (en) 2002-03-10
NZ330886A (en) 1999-02-25
CZ287007B6 (en) 2000-08-16
IL125146A0 (en) 1999-01-26
PL185132B1 (pl) 2003-02-28
US6288079B1 (en) 2001-09-11
NO983877D0 (no) 1998-08-21
BR9707636A (pt) 1999-07-27
HUP9901199A2 (hu) 1999-08-30
JP2000504739A (ja) 2000-04-18
IS4825A (is) 1998-08-17
DE69705608D1 (de) 2001-08-16
CA2244773C (en) 2006-01-03
SG99853A1 (en) 2003-11-27
UA49872C2 (uk) 2002-10-15
US20020128284A1 (en) 2002-09-12
ZA971525B (en) 1997-10-21
SK281813B6 (sk) 2001-08-06
JP3238414B2 (ja) 2001-12-17
ATE203023T1 (de) 2001-07-15
DK0885220T3 (da) 2001-10-15
EP0885220B1 (en) 2001-07-11

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