MXPA05010627A - Derivados de 4-(2-feniloxifenil)-piperidina o 1,2,3,6-tetrahidropiridina como inhibidores de la recaptacion de serotonina. - Google Patents
Derivados de 4-(2-feniloxifenil)-piperidina o 1,2,3,6-tetrahidropiridina como inhibidores de la recaptacion de serotonina.Info
- Publication number
- MXPA05010627A MXPA05010627A MXPA05010627A MXPA05010627A MXPA05010627A MX PA05010627 A MXPA05010627 A MX PA05010627A MX PA05010627 A MXPA05010627 A MX PA05010627A MX PA05010627 A MXPA05010627 A MX PA05010627A MX PA05010627 A MXPA05010627 A MX PA05010627A
- Authority
- MX
- Mexico
- Prior art keywords
- phenyloxyphenyl
- piperidine
- serotonin reuptake
- reuptake inhibitors
- disorder
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Abstract
La invencion proporciona compuestos representados por la formula general I (ver formula I) en donde los sustituyentes se definen en la solicitud. Los compuestos son utiles para el tratamiento de trastornos afectivos, incluyendo la depresion, trastornos de ansiedad, incluyendo el trastorno de ansiedad general, trastorno de panico y trastorno obsesivo-compulsivo.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US46026503P | 2003-04-04 | 2003-04-04 | |
DKPA200300519 | 2003-04-04 | ||
PCT/DK2004/000241 WO2004087155A1 (en) | 2003-04-04 | 2004-04-02 | 4-(2-phenyloxyphenyl)-piperidine or -1,2,3,6-tetrahydropyridine derivatives as serotonin reuptake inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA05010627A true MXPA05010627A (es) | 2005-12-12 |
Family
ID=33132908
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA05010627A MXPA05010627A (es) | 2003-04-04 | 2004-04-02 | Derivados de 4-(2-feniloxifenil)-piperidina o 1,2,3,6-tetrahidropiridina como inhibidores de la recaptacion de serotonina. |
Country Status (18)
Country | Link |
---|---|
US (1) | US20060293360A1 (es) |
EP (1) | EP1635828B1 (es) |
JP (1) | JP2006522027A (es) |
AT (1) | ATE392896T1 (es) |
AU (1) | AU2004226837A1 (es) |
BR (1) | BRPI0408320A (es) |
CO (1) | CO5640133A2 (es) |
DE (1) | DE602004013314T2 (es) |
DK (1) | DK1635828T3 (es) |
ES (1) | ES2303062T3 (es) |
HR (1) | HRP20080262T3 (es) |
MX (1) | MXPA05010627A (es) |
NO (1) | NO20055206L (es) |
NZ (1) | NZ540891A (es) |
PL (1) | PL1635828T3 (es) |
PT (1) | PT1635828E (es) |
SI (1) | SI1635828T1 (es) |
WO (1) | WO2004087155A1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MXPA05009592A (es) | 2003-04-04 | 2005-10-18 | Lundbeck & Co As H | Derivados de 4-(2-fenilsulfanil-fenil)-piperidina como inhibidores de recaptacion de serotonina. |
WO2007144006A1 (en) | 2006-06-16 | 2007-12-21 | H. Lundbeck A/S | Crystalline forms of 4- [2- (4-methylphenylsulfanyl) -phenyl] piperidine with combined serotonin and norepinephrine reuptake inhibition for the treatment of neuropathic pain |
TWI432194B (zh) * | 2007-03-20 | 2014-04-01 | Lundbeck & Co As H | 4-〔2-(4-甲基苯硫基)苯基〕哌啶之新穎治療用途 |
TWI396689B (zh) | 2008-11-14 | 2013-05-21 | Amgen Inc | 作為磷酸二酯酶10抑制劑之吡衍生物 |
TW201030001A (en) | 2008-11-14 | 2010-08-16 | Amgen Inc | Pyridine and pyrimidine derivatives as phosphodiesterase 10 inhibitors |
ES2397247T3 (es) * | 2008-11-14 | 2013-03-05 | Theravance, Inc. | Forma cristalina de un compuesto 4-[2-(2-fluorofenoximetil)fenil]piperidina |
MX2011006575A (es) | 2008-12-17 | 2011-10-06 | Amgen Inc | Compuestos de aminopiridina y carboxipiridina como inhibidores de la fosfodiesterasa 10. |
US8778949B2 (en) * | 2010-01-11 | 2014-07-15 | Theravance Biopharma R&D Ip, Llc | 1-(2-phenoxymethylphenyl)piperazine compounds |
EP2550252B1 (en) * | 2010-03-22 | 2015-05-06 | Theravance Biopharma R&D IP, LLC | 1-(2-phenoxymethylheteroaryl)piperidine and piperazine compounds |
JP5774091B2 (ja) * | 2010-04-22 | 2015-09-02 | セラヴァンス バイオファーマ アール&ディー アイピー, エルエルシー | 疼痛治療のためのセロトニン・ノルエピネフリン再取り込みインヒビターとオピオイド作動物質との組み合わせ |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4241071A (en) * | 1977-01-27 | 1980-12-23 | American Hoechst Corporation | Antidepressant (α-phenyl-2-tolyl)azacycloalkanes |
US4198417A (en) * | 1979-01-10 | 1980-04-15 | American Hoechst Corporation | Phenoxyphenylpiperidines |
AP2001002252A0 (en) * | 1999-02-23 | 2001-09-30 | Pfizer Prod Inc | Monoamine reuptake inhibitors for treatment of CNS disorders. |
AU769430B2 (en) * | 1999-10-13 | 2004-01-29 | Pfizer Products Inc. | Biaryl ether derivatives useful as monoamine reuptake inhibitors |
UA81749C2 (uk) * | 2001-10-04 | 2008-02-11 | Х. Луннбек А/С | Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну |
-
2004
- 2004-04-02 PT PT04725298T patent/PT1635828E/pt unknown
- 2004-04-02 EP EP04725298A patent/EP1635828B1/en not_active Expired - Lifetime
- 2004-04-02 PL PL04725298T patent/PL1635828T3/pl unknown
- 2004-04-02 SI SI200430746T patent/SI1635828T1/sl unknown
- 2004-04-02 DK DK04725298T patent/DK1635828T3/da active
- 2004-04-02 NZ NZ540891A patent/NZ540891A/en unknown
- 2004-04-02 AU AU2004226837A patent/AU2004226837A1/en not_active Abandoned
- 2004-04-02 US US10/551,870 patent/US20060293360A1/en not_active Abandoned
- 2004-04-02 ES ES04725298T patent/ES2303062T3/es not_active Expired - Lifetime
- 2004-04-02 DE DE602004013314T patent/DE602004013314T2/de not_active Expired - Fee Related
- 2004-04-02 MX MXPA05010627A patent/MXPA05010627A/es active IP Right Grant
- 2004-04-02 WO PCT/DK2004/000241 patent/WO2004087155A1/en active IP Right Grant
- 2004-04-02 BR BRPI0408320-2A patent/BRPI0408320A/pt not_active IP Right Cessation
- 2004-04-02 JP JP2006504346A patent/JP2006522027A/ja not_active Withdrawn
- 2004-04-02 AT AT04725298T patent/ATE392896T1/de not_active IP Right Cessation
-
2005
- 2005-10-20 CO CO05106876A patent/CO5640133A2/es unknown
- 2005-11-04 NO NO20055206A patent/NO20055206L/no unknown
-
2008
- 2008-06-12 HR HR20080262T patent/HRP20080262T3/xx unknown
Also Published As
Publication number | Publication date |
---|---|
CO5640133A2 (es) | 2006-05-31 |
DE602004013314T2 (de) | 2008-08-07 |
DE602004013314D1 (de) | 2008-06-05 |
JP2006522027A (ja) | 2006-09-28 |
US20060293360A1 (en) | 2006-12-28 |
WO2004087155A1 (en) | 2004-10-14 |
PT1635828E (pt) | 2008-07-01 |
BRPI0408320A (pt) | 2006-03-07 |
EP1635828A1 (en) | 2006-03-22 |
AU2004226837A1 (en) | 2004-10-14 |
DK1635828T3 (da) | 2008-08-11 |
NO20055206L (no) | 2005-11-04 |
HRP20080262T3 (en) | 2009-04-30 |
ES2303062T3 (es) | 2008-08-01 |
EP1635828B1 (en) | 2008-04-23 |
ATE392896T1 (de) | 2008-05-15 |
SI1635828T1 (sl) | 2008-08-31 |
NZ540891A (en) | 2008-07-31 |
PL1635828T3 (pl) | 2008-10-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |