PL1635828T3 - Pochodne 4-(2-fenyloksyfenylo)-piperydyny lub 1,2,3,6-tetrahydropirydyny jako inhibitory wychwytu zwrotnego serotoniny - Google Patents
Pochodne 4-(2-fenyloksyfenylo)-piperydyny lub 1,2,3,6-tetrahydropirydyny jako inhibitory wychwytu zwrotnego serotoninyInfo
- Publication number
- PL1635828T3 PL1635828T3 PL04725298T PL04725298T PL1635828T3 PL 1635828 T3 PL1635828 T3 PL 1635828T3 PL 04725298 T PL04725298 T PL 04725298T PL 04725298 T PL04725298 T PL 04725298T PL 1635828 T3 PL1635828 T3 PL 1635828T3
- Authority
- PL
- Poland
- Prior art keywords
- phenyloxyphenyl
- piperidine
- serotonin reuptake
- reuptake inhibitors
- disorder
- Prior art date
Links
- YWIYMDPWBAXEKQ-UHFFFAOYSA-N 4-(2-phenoxyphenyl)piperidine Chemical compound C1CNCCC1C1=CC=CC=C1OC1=CC=CC=C1 YWIYMDPWBAXEKQ-UHFFFAOYSA-N 0.000 title 1
- 239000003772 serotonin uptake inhibitor Substances 0.000 title 1
- 208000019901 Anxiety disease Diseases 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000017194 Affective disease Diseases 0.000 abstract 1
- 208000019022 Mood disease Diseases 0.000 abstract 1
- 208000021384 Obsessive-Compulsive disease Diseases 0.000 abstract 1
- 208000019906 panic disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46026503P | 2003-04-04 | 2003-04-04 | |
| DKPA200300519 | 2003-04-04 | ||
| EP04725298A EP1635828B1 (en) | 2003-04-04 | 2004-04-02 | 4-(2-phenyloxyphenyl)-piperidine or -1,2,3,6-tetrahydropyridine derivatives as serotonin reuptake inhibitors |
| PCT/DK2004/000241 WO2004087155A1 (en) | 2003-04-04 | 2004-04-02 | 4-(2-phenyloxyphenyl)-piperidine or -1,2,3,6-tetrahydropyridine derivatives as serotonin reuptake inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1635828T3 true PL1635828T3 (pl) | 2008-10-31 |
Family
ID=33132908
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL04725298T PL1635828T3 (pl) | 2003-04-04 | 2004-04-02 | Pochodne 4-(2-fenyloksyfenylo)-piperydyny lub 1,2,3,6-tetrahydropirydyny jako inhibitory wychwytu zwrotnego serotoniny |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20060293360A1 (pl) |
| EP (1) | EP1635828B1 (pl) |
| JP (1) | JP2006522027A (pl) |
| AT (1) | ATE392896T1 (pl) |
| AU (1) | AU2004226837A1 (pl) |
| BR (1) | BRPI0408320A (pl) |
| CO (1) | CO5640133A2 (pl) |
| DE (1) | DE602004013314T2 (pl) |
| DK (1) | DK1635828T3 (pl) |
| ES (1) | ES2303062T3 (pl) |
| HR (1) | HRP20080262T3 (pl) |
| MX (1) | MXPA05010627A (pl) |
| NO (1) | NO20055206L (pl) |
| NZ (1) | NZ540891A (pl) |
| PL (1) | PL1635828T3 (pl) |
| PT (1) | PT1635828E (pl) |
| SI (1) | SI1635828T1 (pl) |
| WO (1) | WO2004087155A1 (pl) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20080478T3 (hr) | 2003-04-04 | 2009-02-28 | H. Lundbeck A/S | Derivati 4-(2-fenilsulfanil-fenil)-piperidina kaoinhibitori ponovne pohrane serotonina |
| CA2656057C (en) | 2006-06-16 | 2012-10-02 | H. Lundbeck A/S | Crystalline forms of 4-[2-(4-methylphenylsulfanyl)-phenyl]piperidine with combined serotonin and norepinephrine reuptake inhibition for the treatment of neuropathic pain |
| TWI432194B (zh) * | 2007-03-20 | 2014-04-01 | Lundbeck & Co As H | ４-〔２-（４-甲基苯硫基）苯基〕哌啶之新穎治療用途 |
| TW201030001A (en) | 2008-11-14 | 2010-08-16 | Amgen Inc | Pyridine and pyrimidine derivatives as phosphodiesterase 10 inhibitors |
| PT2358675E (pt) * | 2008-11-14 | 2012-12-12 | Theravance Inc | Compostos de 4-[2-(2-fluorofenoximetil)fenil]piperidina |
| TWI396689B (zh) | 2008-11-14 | 2013-05-21 | Amgen Inc | 作為磷酸二酯酶１０抑制劑之吡衍生物 |
| MX2011006575A (es) | 2008-12-17 | 2011-10-06 | Amgen Inc | Compuestos de aminopiridina y carboxipiridina como inhibidores de la fosfodiesterasa 10. |
| US8778949B2 (en) * | 2010-01-11 | 2014-07-15 | Theravance Biopharma R&D Ip, Llc | 1-(2-phenoxymethylphenyl)piperazine compounds |
| ES2543064T3 (es) * | 2010-03-22 | 2015-08-14 | Theravance Biopharma R&D Ip, Llc | Compuestos de 1-(2-fenoximetilheteroaril)piperidina y piperazina |
| MX2012012245A (es) * | 2010-04-22 | 2012-12-17 | Theravance Inc | Combinacion de una reabsorcion de inhibidor de serotonina y norepirefrina y un agonista opioide para el tratamiento del dolor. |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4241071A (en) * | 1977-01-27 | 1980-12-23 | American Hoechst Corporation | Antidepressant (α-phenyl-2-tolyl)azacycloalkanes |
| US4198417A (en) * | 1979-01-10 | 1980-04-15 | American Hoechst Corporation | Phenoxyphenylpiperidines |
| HUP0105488A3 (en) * | 1999-02-23 | 2005-07-28 | Pfizer Prod Inc | Monoamine reuptake inhibitors for treatment of cns disorders and pharmaceutical compositions containing the compounds |
| WO2001027068A1 (en) * | 1999-10-13 | 2001-04-19 | Pfizer Products Inc. | Biaryl ether derivatives useful as monoamine reuptake inhibitors |
| UA81749C2 (uk) * | 2001-10-04 | 2008-02-11 | Х. Луннбек А/С | Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну |
-
2004
- 2004-04-02 PT PT04725298T patent/PT1635828E/pt unknown
- 2004-04-02 NZ NZ540891A patent/NZ540891A/en unknown
- 2004-04-02 AT AT04725298T patent/ATE392896T1/de not_active IP Right Cessation
- 2004-04-02 MX MXPA05010627A patent/MXPA05010627A/es active IP Right Grant
- 2004-04-02 ES ES04725298T patent/ES2303062T3/es not_active Expired - Lifetime
- 2004-04-02 PL PL04725298T patent/PL1635828T3/pl unknown
- 2004-04-02 DK DK04725298T patent/DK1635828T3/da active
- 2004-04-02 EP EP04725298A patent/EP1635828B1/en not_active Expired - Lifetime
- 2004-04-02 WO PCT/DK2004/000241 patent/WO2004087155A1/en not_active Ceased
- 2004-04-02 BR BRPI0408320-2A patent/BRPI0408320A/pt not_active IP Right Cessation
- 2004-04-02 HR HR20080262T patent/HRP20080262T3/xx unknown
- 2004-04-02 DE DE602004013314T patent/DE602004013314T2/de not_active Expired - Fee Related
- 2004-04-02 JP JP2006504346A patent/JP2006522027A/ja not_active Withdrawn
- 2004-04-02 US US10/551,870 patent/US20060293360A1/en not_active Abandoned
- 2004-04-02 SI SI200430746T patent/SI1635828T1/sl unknown
- 2004-04-02 AU AU2004226837A patent/AU2004226837A1/en not_active Abandoned
-
2005
- 2005-10-20 CO CO05106876A patent/CO5640133A2/es unknown
- 2005-11-04 NO NO20055206A patent/NO20055206L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1635828A1 (en) | 2006-03-22 |
| EP1635828B1 (en) | 2008-04-23 |
| NZ540891A (en) | 2008-07-31 |
| DE602004013314T2 (de) | 2008-08-07 |
| JP2006522027A (ja) | 2006-09-28 |
| DK1635828T3 (da) | 2008-08-11 |
| ES2303062T3 (es) | 2008-08-01 |
| BRPI0408320A (pt) | 2006-03-07 |
| ATE392896T1 (de) | 2008-05-15 |
| MXPA05010627A (es) | 2005-12-12 |
| CO5640133A2 (es) | 2006-05-31 |
| PT1635828E (pt) | 2008-07-01 |
| DE602004013314D1 (de) | 2008-06-05 |
| HRP20080262T3 (hr) | 2009-04-30 |
| NO20055206L (no) | 2005-11-04 |
| WO2004087155A1 (en) | 2004-10-14 |
| US20060293360A1 (en) | 2006-12-28 |
| SI1635828T1 (sl) | 2008-08-31 |
| AU2004226837A1 (en) | 2004-10-14 |
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