CY1108464T1 - Παραγωγα 4-(2-φαινυλοσουλφανυλο-φαινυλο)πιπεριδινης, ως αναστολεις επαναπροσληψεως σεροτονινης - Google Patents

Παραγωγα 4-(2-φαινυλοσουλφανυλο-φαινυλο)πιπεριδινης, ως αναστολεις επαναπροσληψεως σεροτονινης

Info

Publication number
CY1108464T1
CY1108464T1 CY20081101225T CY081101225T CY1108464T1 CY 1108464 T1 CY1108464 T1 CY 1108464T1 CY 20081101225 T CY20081101225 T CY 20081101225T CY 081101225 T CY081101225 T CY 081101225T CY 1108464 T1 CY1108464 T1 CY 1108464T1
Authority
CY
Cyprus
Prior art keywords
piperidine
phenylsulfanyl
serotonin
phenyl
derivative
Prior art date
Application number
CY20081101225T
Other languages
English (en)
Inventor
Ask Püschl
Morten Jorgensen
Thomas Ruhland
Stensboi Tine Bryan
Benny Bang-Andersen
Original Assignee
H. Lundbeck A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H. Lundbeck A/S filed Critical H. Lundbeck A/S
Publication of CY1108464T1 publication Critical patent/CY1108464T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/24—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by sulfur atoms to which a second hetero atom is attached

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Η εφεύρεσις προσφέρει ενώσεις παρισταμένας υπό του γενικού τύπου (Ι), εις τον οποίον οι υποκαταστάται καθορίζονται εις την αίτησιν διπλώματος ευρεσιτεχνίας. Αι ενώσεις είναι χρήσιμοι εις την θεραπείαν συναισθηματικής διαταραχής, συμπεριλαμβανομένων καταθλίψεως, διαταραχών άγχους περιλαμβανομένης γενικής διαταραχής άγχους και διαταραχής πανικού, και βασανιστικής καταναγκαστικής διαταραχής.
CY20081101225T 2003-04-04 2008-10-30 Παραγωγα 4-(2-φαινυλοσουλφανυλο-φαινυλο)πιπεριδινης, ως αναστολεις επαναπροσληψεως σεροτονινης CY1108464T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US46052803P 2003-04-04 2003-04-04
DKPA200300520 2003-04-04
EP04725291A EP1626720B1 (en) 2003-04-04 2004-04-02 4-(2-phenylsulfanyl-phenyl)-piperidine derivatives as serotonin reuptake inhibitors

Publications (1)

Publication Number Publication Date
CY1108464T1 true CY1108464T1 (el) 2014-04-09

Family

ID=33132909

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20081101225T CY1108464T1 (el) 2003-04-04 2008-10-30 Παραγωγα 4-(2-φαινυλοσουλφανυλο-φαινυλο)πιπεριδινης, ως αναστολεις επαναπροσληψεως σεροτονινης

Country Status (19)

Country Link
US (1) US7732463B2 (el)
EP (1) EP1626720B1 (el)
JP (1) JP4667366B2 (el)
AT (1) ATE406894T1 (el)
AU (1) AU2004226838B8 (el)
CA (1) CA2521258C (el)
CO (1) CO5700748A2 (el)
CY (1) CY1108464T1 (el)
DE (1) DE602004016316D1 (el)
DK (1) DK1626720T3 (el)
ES (1) ES2309514T3 (el)
HR (1) HRP20080478T3 (el)
IL (1) IL171087A (el)
MX (1) MXPA05009592A (el)
NO (1) NO20055208L (el)
PL (1) PL1626720T3 (el)
PT (1) PT1626720E (el)
SI (1) SI1626720T1 (el)
WO (1) WO2004087156A1 (el)

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UA81749C2 (uk) 2001-10-04 2008-02-11 Х. Луннбек А/С Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну
WO2006022420A1 (ja) 2004-08-25 2006-03-02 Takeda Pharmaceutical Company Limited 腹圧性尿失禁の予防・治療剤及びそのスクリーニング方法
EP2742936A1 (en) 2006-05-16 2014-06-18 Takeda Pharmaceutical Company Limited Fused heterocyclic compound and use thereof
BR122020011920A2 (pt) * 2006-06-16 2020-08-25 Lundbeck & Co As H composto, composição farmacêutica, método para tratar uma doença, uso de um composto, e processos para a preparação de um composto, e para a fabricação de um composto
TWI405588B (zh) * 2007-03-20 2013-08-21 Lundbeck & Co As H ４-〔２-（４-甲苯基硫基）-苯基〕哌啶之鹽類的液體調配物
TWI432194B (zh) * 2007-03-20 2014-04-01 Lundbeck & Co As H ４-〔２-（４-甲基苯硫基）苯基〕哌啶之新穎治療用途
TW200932233A (en) 2007-11-13 2009-08-01 Lundbeck & Co As H Therapeutic uses of compounds having combined SERT, 5-HT3 and 5-HT1a activity
US20100266504A1 (en) 2007-11-15 2010-10-21 Takahiro Matsumoto Condensed pyridine derivative and use thereof
TW200938194A (en) * 2007-12-14 2009-09-16 Lundbeck & Co As H Therapeutic uses of compounds having affinity to the serotonin transporter, serotonin receptors and noradrenalin transporter
TW200932225A (en) * 2007-12-14 2009-08-01 Lundbeck & Co As H 4-[2,3-difluoro-6-(2-fluoro-4-methyl-phenylsulfanyl)-phenyl]-piperidine
UA98698C2 (en) * 2008-03-03 2012-06-11 Х. Луннбек А/С Phenylsulfanylphenyl-piperidines and process for the preparation thereof
GEP20135938B (en) 2009-04-24 2013-10-10 H Lundbeck As Liquid pharmaceutical formulations of 1-[2-(2,4-dimethylsulfanyl)phenyl]piperazine
WO2011071136A1 (ja) 2009-12-11 2011-06-16 アステラス製薬株式会社 線維筋痛症治療剤
MA34261B1 (fr) * 2010-04-30 2013-05-02 Takeda Pharmaceutcal Company Ltd Comprime a delitage intestinal
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US20210052600A1 (en) 2017-12-27 2021-02-25 Takeda Pharmaceutical Company Limited Therapeutic agents for stress urinary incontinence and incotinence of feces
AU2019232437A1 (en) 2018-03-07 2020-10-08 Bayer Aktiengesellschaft Identification and use of ERK5 inhibitors
WO2023218484A1 (en) 2022-05-11 2023-11-16 Pi Industries Ltd. Bicyclic compounds and their use as pest control agents

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Also Published As

Publication number Publication date
AU2004226838A1 (en) 2004-10-14
ATE406894T1 (de) 2008-09-15
CO5700748A2 (es) 2006-11-30
MXPA05009592A (es) 2005-10-18
EP1626720A1 (en) 2006-02-22
WO2004087156A1 (en) 2004-10-14
EP1626720B1 (en) 2008-09-03
AU2004226838B8 (en) 2009-06-11
PL1626720T3 (pl) 2009-02-27
PT1626720E (pt) 2008-11-10
ES2309514T3 (es) 2008-12-16
IL171087A (en) 2011-01-31
JP4667366B2 (ja) 2011-04-13
DK1626720T3 (da) 2008-12-01
DE602004016316D1 (de) 2008-10-16
SI1626720T1 (sl) 2008-12-31
JP2006522030A (ja) 2006-09-28
US20060100242A1 (en) 2006-05-11
AU2004226838B2 (en) 2009-02-12
CA2521258C (en) 2009-12-01
NO20055208L (no) 2005-11-04
US7732463B2 (en) 2010-06-08
CA2521258A1 (en) 2004-10-14
HRP20080478T3 (en) 2009-02-28

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