ATE471320T1 - 4-aminopiperidinderivate als inhibitoren der monoamin-aufnahme - Google Patents
4-aminopiperidinderivate als inhibitoren der monoamin-aufnahmeInfo
- Publication number
- ATE471320T1 ATE471320T1 AT05722890T AT05722890T ATE471320T1 AT E471320 T1 ATE471320 T1 AT E471320T1 AT 05722890 T AT05722890 T AT 05722890T AT 05722890 T AT05722890 T AT 05722890T AT E471320 T1 ATE471320 T1 AT E471320T1
- Authority
- AT
- Austria
- Prior art keywords
- inhibitors
- aminopiperidine derivatives
- monoamine absorption
- monoamine
- absorption
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US54867904P | 2004-02-27 | 2004-02-27 | |
PCT/US2005/004174 WO2005092885A1 (en) | 2004-02-27 | 2005-02-11 | 4-amino-piperidine derivatives as monoamine uptake inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE471320T1 true ATE471320T1 (de) | 2010-07-15 |
Family
ID=34961148
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT05722890T ATE471320T1 (de) | 2004-02-27 | 2005-02-11 | 4-aminopiperidinderivate als inhibitoren der monoamin-aufnahme |
Country Status (6)
Country | Link |
---|---|
US (1) | US7521462B2 (de) |
EP (1) | EP1735302B1 (de) |
AT (1) | ATE471320T1 (de) |
DE (1) | DE602005021871D1 (de) |
ES (1) | ES2345261T3 (de) |
WO (1) | WO2005092885A1 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2007296301A1 (en) * | 2006-09-11 | 2008-03-20 | Glaxo Group Limited | Azabicyclic compounds as inhibitors of monoamines reuptake |
WO2008103615A1 (en) * | 2007-02-21 | 2008-08-28 | Kalypsys, Inc. | Isoquinolines useful as inducible nitric oxide synthase inhibitors |
EP2008996A1 (de) | 2007-06-27 | 2008-12-31 | Syngeta Participations AG | Verfahren zur Herstellung von Pyrazolen |
CA2707161C (en) * | 2007-11-28 | 2016-08-16 | Sequoia Pharmaceuticals, Inc. | Compositions and methods for inhibiting cytochrome p450 2d6 |
AU2017239816B9 (en) * | 2016-03-31 | 2020-09-24 | Fujifilm Corporation | Method for producing 5-(bromomethyl)-1-benzothiophene |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2334358A1 (fr) * | 1975-12-12 | 1977-07-08 | Sogeras | Nouveaux medicaments derives de l'indole |
US4861785A (en) * | 1984-12-03 | 1989-08-29 | Janssen Pharmaceutica N.V. | Benzoxazol-and benzothiazolamine derivatives, useful as anti-anoxic agents |
GB9226111D0 (en) | 1992-12-15 | 1993-02-10 | Smithkline Beecham Plc | Madicaments |
US6303627B1 (en) | 1998-06-19 | 2001-10-16 | Eli Lilly And Company | Inhibitors of serotonin reuptake |
ES2157148B1 (es) * | 1998-11-18 | 2002-03-01 | Faes Fabrica Espanola De Produ | Nuevas piperidinas 4-sustituidas. |
US6498161B1 (en) | 1999-04-06 | 2002-12-24 | Merck & Co., Inc. | Pyrrolidine modulators of chemokine receptor activity |
EP1212319A2 (de) | 1999-09-14 | 2002-06-12 | Abbott Laboratories | 3-pyrrolidinyloxy-3' -pyridyl ether verbindungen verwendbar zur steuerung von chemischer synaptischer übertragung |
GB0011838D0 (en) | 2000-05-17 | 2000-07-05 | Astrazeneca Ab | Chemical compounds |
KR20030029978A (ko) | 2000-09-25 | 2003-04-16 | 액테리온 파마슈티칼 리미티드 | 말라리아에 유용한 치환된 아미노-아자-사이클로알칸 |
US7812035B2 (en) | 2001-12-11 | 2010-10-12 | Sepracor Inc. | 4-substituted piperidines, and methods of use thereof |
US7067517B2 (en) | 2001-12-14 | 2006-06-27 | Nero Nordisk A/S | Use of compounds for decreasing activity of hormone-sensitive lipase |
MY134200A (en) | 2002-04-12 | 2007-11-30 | Kowa Co | Method for treating cancer |
US20060079554A1 (en) | 2002-12-06 | 2006-04-13 | Barry Peter C | Inhibitors of monomine uptake |
WO2005000811A1 (en) | 2003-06-11 | 2005-01-06 | Eli Lilly And Company | 3-aminopyrrolidines as inhibitors of monoamine uptake |
US7432280B2 (en) * | 2003-06-20 | 2008-10-07 | Eli Lilly And Company | 3-aminopiperidines and 3-aminoquinuclidines as inhibitors of monoamine uptake |
-
2005
- 2005-02-11 WO PCT/US2005/004174 patent/WO2005092885A1/en active Application Filing
- 2005-02-11 DE DE602005021871T patent/DE602005021871D1/de active Active
- 2005-02-11 AT AT05722890T patent/ATE471320T1/de not_active IP Right Cessation
- 2005-02-11 ES ES05722890T patent/ES2345261T3/es active Active
- 2005-02-11 US US10/597,795 patent/US7521462B2/en not_active Expired - Fee Related
- 2005-02-11 EP EP05722890A patent/EP1735302B1/de not_active Not-in-force
Also Published As
Publication number | Publication date |
---|---|
US20070093526A1 (en) | 2007-04-26 |
EP1735302B1 (de) | 2010-06-16 |
WO2005092885A1 (en) | 2005-10-06 |
ES2345261T3 (es) | 2010-09-20 |
DE602005021871D1 (de) | 2010-07-29 |
EP1735302A1 (de) | 2006-12-27 |
US7521462B2 (en) | 2009-04-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20082880L (no) | Inhibitorer av C-MET samt anvendelse derav | |
NO20062677L (no) | Benzyleteraminforbindelser anvendbare som CCR-5-antagonister | |
NO20060402L (no) | 3-amino choman og 2-aminotetralinderivater | |
DE602006007556D1 (de) | Heteroarylsulfonylstilbene als 5-ht2a-antagonisten | |
NO20055208L (no) | 4-(2-fenylsulfanyl-fenyl)-piperidinderivater som serotonin-reopptaksinhibitorer | |
TW200510403A (en) | Cyclic protein tyrosine kinase inhibitors | |
NO20064325L (no) | Heteroarylaminopyrazolderivativer nyttige for behandling av diabetes | |
ATE421518T1 (de) | Dihydrochinazolinone als 5ht-modulatoren | |
ATE553093T1 (de) | Indazolderivate zur hemmung von trpv1 und verwendungen davon | |
ATE553106T1 (de) | Heteroarylpyrrolopyridinone als kinaseinhibitoren | |
EA201001481A1 (ru) | Производные третичного амина в качестве ингибиторов фосфодиэстеразы-4 | |
DK1641456T3 (da) | Gaboxadol til behandling af depression og andre affektive lidelser | |
NO20055205L (no) | 4-(2-fcnylsulfanyl-fenyl)-1,2,3,6-tydropyridinderivater som serotoniniopptaksinhibitorer | |
SE0401465D0 (sv) | New substituted piperdines as modulators of dopamine neurotransmission | |
NO20055206L (no) | 4-(2-fenyloksyfenyl)-piperidin eller -1,2,3,6-tetrahydropyridinderivater som serotonin-reopptaksinhibitorer | |
EA200801120A1 (ru) | Нафтильные производные в качестве ингибиторов агрегирования бета-амилоида | |
ATE471320T1 (de) | 4-aminopiperidinderivate als inhibitoren der monoamin-aufnahme | |
WO2004052858A3 (en) | Inhibitors of monoamine uptake | |
ATE440836T1 (de) | Verbindungen | |
UA94054C2 (en) | Nitrocatechol derivatives as comt inhibitors | |
ATE419242T1 (de) | Pyrrolidinylharnstoffderivate als angiogeneseinhibitoren | |
ATE532514T1 (de) | Piperidin- und piperazinderivate | |
ATE533769T1 (de) | Als kinaseinhibitoren geeignete pyrrolotriazinverbindungen | |
ATE423772T1 (de) | Morpholinderivate als inhibitoren der wiederaufnahme von norepinephrin | |
NO20062700L (no) | Morfolinderivater som norepinefrin reopptaksinhibitorer |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |