MX2012012245A - Combinacion de una reabsorcion de inhibidor de serotonina y norepirefrina y un agonista opioide para el tratamiento del dolor. - Google Patents

Combinacion de una reabsorcion de inhibidor de serotonina y norepirefrina y un agonista opioide para el tratamiento del dolor.

Info

Publication number
MX2012012245A
MX2012012245A MX2012012245A MX2012012245A MX2012012245A MX 2012012245 A MX2012012245 A MX 2012012245A MX 2012012245 A MX2012012245 A MX 2012012245A MX 2012012245 A MX2012012245 A MX 2012012245A MX 2012012245 A MX2012012245 A MX 2012012245A
Authority
MX
Mexico
Prior art keywords
opioid agonist
combination
pain
serotonin
reuptake inhibitor
Prior art date
Application number
MX2012012245A
Other languages
English (en)
Inventor
William J Martin
Fei Shen
Jacqueline A M Smith
Original Assignee
Theravance Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theravance Inc filed Critical Theravance Inc
Publication of MX2012012245A publication Critical patent/MX2012012245A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La invención proporciona un método de tratamiento de una afección de dolor en un mamífero utilizando un inhibidor de reabsorción específico de serotonina e inhibidor de reabsorción de norepirefrina (SNRI) y también la combinación del SNRI y un agente agonista opioide. La invención incluye métodos en donde el agente agonista opioide se administra en una dosis que es más baja que una dosis administrada para tratar una afección de dolor cuando se usa sola.
MX2012012245A 2010-04-22 2011-04-21 Combinacion de una reabsorcion de inhibidor de serotonina y norepirefrina y un agonista opioide para el tratamiento del dolor. MX2012012245A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32694410P 2010-04-22 2010-04-22
PCT/US2011/033461 WO2011133790A2 (en) 2010-04-22 2011-04-21 Combination of a serotonin and norepinephrine reuptake inhibitor and an opioid agonist for the treatment of pain

Publications (1)

Publication Number Publication Date
MX2012012245A true MX2012012245A (es) 2012-12-17

Family

ID=44259813

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012012245A MX2012012245A (es) 2010-04-22 2011-04-21 Combinacion de una reabsorcion de inhibidor de serotonina y norepirefrina y un agonista opioide para el tratamiento del dolor.

Country Status (9)

Country Link
US (1) US20110263631A1 (es)
EP (1) EP2560646B1 (es)
JP (1) JP5774091B2 (es)
CN (1) CN102858339B (es)
CA (1) CA2794127A1 (es)
ES (1) ES2532204T3 (es)
MX (1) MX2012012245A (es)
RU (1) RU2012149695A (es)
WO (1) WO2011133790A2 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2845625A1 (en) * 2013-09-04 2015-03-11 Grünenthal GmbH Tapentadol for use in the treatment of fibromyalgia and chronic fatigue syndrome

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6602911B2 (en) * 2001-11-05 2003-08-05 Cypress Bioscience, Inc. Methods of treating fibromyalgia
US20040235925A1 (en) * 2002-12-17 2004-11-25 Pharmacia Corporation Method for the treatment, prevention, or inhibition of a CNS disorder and/or pain and inflammation using a combination of duloxetine, venlafaxine or atomoxetine and a cyclooxygenase-2 selective inhibitor and compositions thereof
PT1635828E (pt) * 2003-04-04 2008-07-01 Lundbeck & Co As H Derivados de 4-(2-feniloxifenil) piperidina ou de 1,2,3,6-tetrahidropiridina como inibidores da recaptação da serotonina
PT2358675E (pt) 2008-11-14 2012-12-12 Theravance Inc Compostos de 4-[2-(2-fluorofenoximetil)fenil]piperidina

Also Published As

Publication number Publication date
CN102858339A (zh) 2013-01-02
WO2011133790A2 (en) 2011-10-27
JP5774091B2 (ja) 2015-09-02
WO2011133790A3 (en) 2012-08-09
JP2013525372A (ja) 2013-06-20
ES2532204T3 (es) 2015-03-25
CN102858339B (zh) 2015-04-22
RU2012149695A (ru) 2014-05-27
EP2560646B1 (en) 2014-12-17
CA2794127A1 (en) 2011-10-27
US20110263631A1 (en) 2011-10-27
EP2560646A2 (en) 2013-02-27

Similar Documents

Publication Publication Date Title
PH12012502162A1 (en) Combination therapy
IN2012DN01869A (es)
GEP20227387B (en) Methods and compositions for treating sleep apnea
TN2011000281A1 (en) Dosage regimen of an s1p receptor agonist
CA2909335C (en) Fenfluramine for use in the treatment of dravet syndrome
PH12013501244A1 (en) A combination of an opioid agonist and an opioid antagonist in the treatment of parkinson's disease
TN2011000272A1 (en) Dosage regimen for a s1p agonist
MX2009010929A (es) Terapias de combinacion que comprenden inhibidores de quinoxalina de pi3k-alfa para uso en el tratamiento del cancer.
MX2012000817A (es) Tratamiento para desordenes del higado con inhibidores pi3k.
IN2012DN02782A (es)
PH12016501015A1 (en) Combinations of histone deacetylase inhibitors and immunomodulatory drugs
MX337614B (es) Tratamiento de lupus nefritis usando laquinimod.
EA201690745A1 (ru) Способы лечения и предотвращения болезни "трансплантат против хозяина"
PH12012501741A1 (en) Treatment of lupus arthritis using laquinimod
MY150600A (en) Use of opioid antagonists for treating urinary retention
PH12016500140A1 (en) Heterobicycloaryl rorc2 inhibitors and methods of use thereof
MX353105B (es) Combinaciones de agonistas del receptor beta-3-adrenergico y antagonistas del receptor muscarinico para tratar vejiga hiperactiva.
MX2016004741A (es) Composicion farmaceutica que comprende un antagonista de trpa1 y un agente analgesico.
MX365321B (es) Métodos para el tratamiento de neutropenia mediante agonistas retinoides.
NZ610136A (en) Composition and method for treating skin conditions
MX2015010296A (es) Tratamiento de formas progresivas de esclerosis multiple con laquinimod.
WO2013039956A3 (en) Compositions and methods for treating mood disorders
MX2016007370A (es) Agente terapeutico y/o preventivo que comprende un derivado de 1-indansulfamida para el dolor.
MX2022007113A (es) Inhibidores de la desmetilasa de la histona especifica de la lisina para el tratamiento de las neoplasias mieloproliferativas.
PH12013500471A1 (en) Compound composition for inhalation used for treating asthma

Legal Events

Date Code Title Description
FG Grant or registration