HRP20080262T3 - 4-(2-phenyloxyphenyl)-piperidine or -1,2,3,6-tetrahydropyridine derivatives as serotonin reuptake inhibitors - Google Patents
4-(2-phenyloxyphenyl)-piperidine or -1,2,3,6-tetrahydropyridine derivatives as serotonin reuptake inhibitorsInfo
- Publication number
- HRP20080262T3 HRP20080262T3 HR20080262T HRP20080262T HRP20080262T3 HR P20080262 T3 HRP20080262 T3 HR P20080262T3 HR 20080262 T HR20080262 T HR 20080262T HR P20080262 T HRP20080262 T HR P20080262T HR P20080262 T3 HRP20080262 T3 HR P20080262T3
- Authority
- HR
- Croatia
- Prior art keywords
- phenyloxyphenyl
- piperidine
- serotonin reuptake
- reuptake inhibitors
- disorder
- Prior art date
Links
- YWIYMDPWBAXEKQ-UHFFFAOYSA-N 4-(2-phenoxyphenyl)piperidine Chemical compound C1CNCCC1C1=CC=CC=C1OC1=CC=CC=C1 YWIYMDPWBAXEKQ-UHFFFAOYSA-N 0.000 title 1
- 239000003772 serotonin uptake inhibitor Substances 0.000 title 1
- 208000019901 Anxiety disease Diseases 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000017194 Affective disease Diseases 0.000 abstract 1
- 208000019022 Mood disease Diseases 0.000 abstract 1
- 208000021384 Obsessive-Compulsive disease Diseases 0.000 abstract 1
- 208000019906 panic disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46026503P | 2003-04-04 | 2003-04-04 | |
| DKPA200300519 | 2003-04-04 | ||
| PCT/DK2004/000241 WO2004087155A1 (en) | 2003-04-04 | 2004-04-02 | 4-(2-phenyloxyphenyl)-piperidine or -1,2,3,6-tetrahydropyridine derivatives as serotonin reuptake inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20080262T3 true HRP20080262T3 (en) | 2009-04-30 |
Family
ID=33132908
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20080262T HRP20080262T3 (en) | 2003-04-04 | 2008-06-12 | 4-(2-phenyloxyphenyl)-piperidine or -1,2,3,6-tetrahydropyridine derivatives as serotonin reuptake inhibitors |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20060293360A1 (xx) |
| EP (1) | EP1635828B1 (xx) |
| JP (1) | JP2006522027A (xx) |
| AT (1) | ATE392896T1 (xx) |
| AU (1) | AU2004226837A1 (xx) |
| BR (1) | BRPI0408320A (xx) |
| CO (1) | CO5640133A2 (xx) |
| DE (1) | DE602004013314T2 (xx) |
| DK (1) | DK1635828T3 (xx) |
| ES (1) | ES2303062T3 (xx) |
| HR (1) | HRP20080262T3 (xx) |
| MX (1) | MXPA05010627A (xx) |
| NO (1) | NO20055206L (xx) |
| NZ (1) | NZ540891A (xx) |
| PL (1) | PL1635828T3 (xx) |
| PT (1) | PT1635828E (xx) |
| SI (1) | SI1635828T1 (xx) |
| WO (1) | WO2004087155A1 (xx) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI1626720T1 (sl) | 2003-04-04 | 2008-12-31 | Lundbeck & Co As H | Derivati 4-(2-fenilsulfanil-fenil)-piperidina kotzaviralci ponovnega vnosa serotonina |
| JP5318757B2 (ja) | 2006-06-16 | 2013-10-16 | ハー・ルンドベック・アクチエゼルスカベット | 神経因性疼痛の治療のための、組み合わされたセロトニンおよびノルエピネフリン再取り込み阻害を有する４−［２−（４−メチルフェニルスルファニル）−フェニル］ピペリジンの結晶形 |
| TWI432194B (zh) * | 2007-03-20 | 2014-04-01 | Lundbeck & Co As H | ４-〔２-（４-甲基苯硫基）苯基〕哌啶之新穎治療用途 |
| TWI396689B (zh) | 2008-11-14 | 2013-05-21 | Amgen Inc | 作為磷酸二酯酶１０抑制劑之吡衍生物 |
| AR074343A1 (es) | 2008-11-14 | 2011-01-12 | Amgen Inc | Derivados de piridina y pirimidina como inhibidores de la fosfodiesterasa 10 |
| EP2358675B9 (en) * | 2008-11-14 | 2019-09-11 | Theravance, Inc. | 4-[2-(2-Fluorophenoxymethyl)phenyl]piperidine compounds |
| CA2746307C (en) | 2008-12-17 | 2013-11-19 | Amgen Inc. | Aminopyridine and carboxypyridine compounds as phosphodiesterase 10 inhibitors |
| JP5705239B2 (ja) | 2010-01-11 | 2015-04-22 | セラヴァンス バイオファーマ アール＆ディー アイピー， エルエルシー | セロトニンおよびノルエピネフリン再取込みインヒビターとしての１−（２−フェノキシメチルフェニル）ピペラジン化合物 |
| WO2011119461A1 (en) * | 2010-03-22 | 2011-09-29 | Theravance, Inc. | 1-(2-phenoxymethylheteroaryl)piperidine and piperazine compounds |
| MX2012012245A (es) * | 2010-04-22 | 2012-12-17 | Theravance Inc | Combinacion de una reabsorcion de inhibidor de serotonina y norepirefrina y un agonista opioide para el tratamiento del dolor. |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4241071A (en) * | 1977-01-27 | 1980-12-23 | American Hoechst Corporation | Antidepressant (α-phenyl-2-tolyl)azacycloalkanes |
| US4198417A (en) * | 1979-01-10 | 1980-04-15 | American Hoechst Corporation | Phenoxyphenylpiperidines |
| CZ20013023A3 (cs) * | 1999-02-23 | 2002-02-13 | Pfizer Products Inc. | Inhibitory zpětného vychytávání monoaminu pro léčbu onemocnění CNS |
| HUP0203448A3 (en) * | 1999-10-13 | 2005-07-28 | Pfizer Prod Inc | Biaryl ether derivatives useful as monoamine reuptake inhibitors and pharmaceutical compositions containing them |
| UA81749C2 (uk) * | 2001-10-04 | 2008-02-11 | Х. Луннбек А/С | Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну |
-
2004
- 2004-04-02 SI SI200430746T patent/SI1635828T1/sl unknown
- 2004-04-02 EP EP04725298A patent/EP1635828B1/en not_active Expired - Lifetime
- 2004-04-02 PT PT04725298T patent/PT1635828E/pt unknown
- 2004-04-02 PL PL04725298T patent/PL1635828T3/pl unknown
- 2004-04-02 MX MXPA05010627A patent/MXPA05010627A/es active IP Right Grant
- 2004-04-02 US US10/551,870 patent/US20060293360A1/en not_active Abandoned
- 2004-04-02 AT AT04725298T patent/ATE392896T1/de not_active IP Right Cessation
- 2004-04-02 JP JP2006504346A patent/JP2006522027A/ja not_active Withdrawn
- 2004-04-02 AU AU2004226837A patent/AU2004226837A1/en not_active Abandoned
- 2004-04-02 DK DK04725298T patent/DK1635828T3/da active
- 2004-04-02 BR BRPI0408320-2A patent/BRPI0408320A/pt not_active IP Right Cessation
- 2004-04-02 NZ NZ540891A patent/NZ540891A/en unknown
- 2004-04-02 DE DE602004013314T patent/DE602004013314T2/de not_active Expired - Fee Related
- 2004-04-02 WO PCT/DK2004/000241 patent/WO2004087155A1/en active IP Right Grant
- 2004-04-02 ES ES04725298T patent/ES2303062T3/es not_active Expired - Lifetime
-
2005
- 2005-10-20 CO CO05106876A patent/CO5640133A2/es unknown
- 2005-11-04 NO NO20055206A patent/NO20055206L/no unknown
-
2008
- 2008-06-12 HR HR20080262T patent/HRP20080262T3/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE602004013314D1 (de) | 2008-06-05 |
| AU2004226837A1 (en) | 2004-10-14 |
| EP1635828B1 (en) | 2008-04-23 |
| BRPI0408320A (pt) | 2006-03-07 |
| EP1635828A1 (en) | 2006-03-22 |
| PL1635828T3 (pl) | 2008-10-31 |
| CO5640133A2 (es) | 2006-05-31 |
| NO20055206L (no) | 2005-11-04 |
| ATE392896T1 (de) | 2008-05-15 |
| NZ540891A (en) | 2008-07-31 |
| DK1635828T3 (da) | 2008-08-11 |
| WO2004087155A1 (en) | 2004-10-14 |
| US20060293360A1 (en) | 2006-12-28 |
| PT1635828E (pt) | 2008-07-01 |
| ES2303062T3 (es) | 2008-08-01 |
| DE602004013314T2 (de) | 2008-08-07 |
| SI1635828T1 (sl) | 2008-08-31 |
| MXPA05010627A (es) | 2005-12-12 |
| JP2006522027A (ja) | 2006-09-28 |
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