EE03618B1 - Bitsüklilised tahhükiniini antagonistid, nende valmistamine ja kasutamine ravimsegus - Google Patents

Bitsüklilised tahhükiniini antagonistid, nende valmistamine ja kasutamine ravimsegus

Info

Publication number
EE03618B1
EE03618B1 EE9700230A EE9700230A EE03618B1 EE 03618 B1 EE03618 B1 EE 03618B1 EE 9700230 A EE9700230 A EE 9700230A EE 9700230 A EE9700230 A EE 9700230A EE 03618 B1 EE03618 B1 EE 03618B1
Authority
EE
Estonia
Prior art keywords
bicyclic
preparation
pharmaceutical composition
tachykinin antagonists
tachykinin
Prior art date
Application number
EE9700230A
Other languages
English (en)
Estonian (et)
Other versions
EE9700230A (et
Inventor
Alberto Maggi Carlo
Arcamone Federico
Quartara Laura
Giannotti Danilo
Original Assignee
A. Menarini Industrie Farmaceutiche Riunite S.R.L.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11351134&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EE03618(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by A. Menarini Industrie Farmaceutiche Riunite S.R.L. filed Critical A. Menarini Industrie Farmaceutiche Riunite S.R.L.
Publication of EE9700230A publication Critical patent/EE9700230A/xx
Publication of EE03618B1 publication Critical patent/EE03618B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/22—Tachykinins, e.g. Eledoisins, Substance P; Related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Virology (AREA)
  • Reproductive Health (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
EE9700230A 1995-03-13 1996-03-11 Bitsüklilised tahhükiniini antagonistid, nende valmistamine ja kasutamine ravimsegus EE03618B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT95FI000044A IT1277835B1 (it) 1995-03-13 1995-03-13 Composti biciclici, loro preparazione ed uso in composizioni farmaceutiche
PCT/EP1996/001028 WO1996028467A1 (en) 1995-03-13 1996-03-11 Bicyclic tachykinins antagonists, preparation thereof and their use in pharmaceutical composition

Publications (2)

Publication Number Publication Date
EE9700230A EE9700230A (et) 1998-04-15
EE03618B1 true EE03618B1 (et) 2002-02-15

Family

ID=11351134

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9700230A EE03618B1 (et) 1995-03-13 1996-03-11 Bitsüklilised tahhükiniini antagonistid, nende valmistamine ja kasutamine ravimsegus

Country Status (33)

Country Link
US (1) US6150325A (ko)
EP (1) EP0815126B1 (ko)
JP (1) JP4618821B2 (ko)
KR (1) KR100405009B1 (ko)
CN (1) CN1189477C (ko)
AR (1) AR004476A1 (ko)
AT (1) ATE198481T1 (ko)
AU (1) AU696528B2 (ko)
BG (1) BG63208B1 (ko)
BR (1) BR9607348A (ko)
CZ (1) CZ287372B6 (ko)
DE (1) DE69611438T2 (ko)
DK (1) DK0815126T3 (ko)
EA (1) EA000697B1 (ko)
EE (1) EE03618B1 (ko)
ES (1) ES2155187T3 (ko)
GE (1) GEP20002271B (ko)
GR (1) GR3035676T3 (ko)
HR (1) HRP960117B1 (ko)
HU (1) HU222051B1 (ko)
IL (1) IL117395A (ko)
IT (1) IT1277835B1 (ko)
MX (1) MX9706927A (ko)
NO (1) NO319290B1 (ko)
NZ (1) NZ303982A (ko)
PL (1) PL184147B1 (ko)
PT (1) PT815126E (ko)
RO (1) RO118297B1 (ko)
SK (1) SK281899B6 (ko)
TW (1) TW565572B (ko)
UA (1) UA48962C2 (ko)
WO (1) WO1996028467A1 (ko)
ZA (1) ZA961983B (ko)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6017705A (en) * 1995-03-14 2000-01-25 Ludwig Institute For Cancer Research Isolated nucleic acid molecules which are members of the MAGE-B family and uses thereof
IT1291776B1 (it) * 1997-02-07 1999-01-21 Menarini Ricerche Spa Composti monociclici a quattro residui bifunzionali, aventi azione nk-2 antagonista
IT1304888B1 (it) * 1998-08-05 2001-04-05 Menarini Ricerche Spa Composti monociclici ad azione nk-2 antagonista e formulazioni che licontengono
NZ523310A (en) * 2000-06-12 2005-07-29 Univ Rochester Tachykinin receptor antagonist to block receptors NK1, NK2, and NK3 and treat symptoms of hormonal variation
EP1297826A1 (en) * 2001-09-27 2003-04-02 Menarini Ricerche S.p.A. Nasal pharmaceutical compositions containing a NK-2 antagonist
ITFI20020239A1 (it) 2002-12-06 2004-06-07 Menarini Ricerche Spa Processo per la preparazione di composti peptidici biciclici.
ITFI20040221A1 (it) * 2004-10-27 2005-01-27 Guidotti & C Spa Composizioni farmaceutiche a base di nk2 antagonisti per uso pediatrico
ITRM20120331A1 (it) 2012-07-12 2014-01-13 Guidotti & C Spa Labor Composizioni pediatriche orali liquide contenenti nepadutant.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1262902B (it) * 1992-04-15 1996-07-22 Menarini Farma Ind Composti triciclici antagonisti delle tachichinine, loro preparazione e loro uso in composizioni farmaceutiche.

Also Published As

Publication number Publication date
ITFI950044A1 (it) 1996-09-13
PT815126E (pt) 2001-06-29
DE69611438D1 (de) 2001-02-08
IT1277835B1 (it) 1997-11-12
JPH11501643A (ja) 1999-02-09
KR100405009B1 (ko) 2004-05-20
BG101849A (en) 1998-04-30
CN1189477C (zh) 2005-02-16
DE69611438T2 (de) 2001-06-13
TW565572B (en) 2003-12-11
HUP9801835A2 (hu) 1999-01-28
GR3035676T3 (en) 2001-06-29
ITFI950044A0 (it) 1995-03-13
NO319290B1 (no) 2005-07-11
CN1183786A (zh) 1998-06-03
ZA961983B (en) 1997-09-29
ATE198481T1 (de) 2001-01-15
UA48962C2 (uk) 2002-09-16
MX9706927A (es) 1997-11-29
PL184147B1 (pl) 2002-09-30
GEP20002271B (en) 2000-10-25
DK0815126T3 (da) 2001-05-07
EP0815126B1 (en) 2001-01-03
AU5105996A (en) 1996-10-02
AR004476A1 (es) 1998-12-16
PL322105A1 (en) 1998-01-05
BR9607348A (pt) 1997-12-30
EE9700230A (et) 1998-04-15
JP4618821B2 (ja) 2011-01-26
NO974057D0 (no) 1997-09-03
WO1996028467A1 (en) 1996-09-19
NZ303982A (en) 1998-04-27
CZ287372B6 (en) 2000-11-15
NO974057L (no) 1997-11-07
US6150325A (en) 2000-11-21
EA000697B1 (ru) 2000-02-28
HU222051B1 (hu) 2003-04-28
RO118297B1 (ro) 2003-04-30
AU696528B2 (en) 1998-09-10
KR19980703011A (ko) 1998-09-05
ES2155187T3 (es) 2001-05-01
BG63208B1 (bg) 2001-06-29
IL117395A (en) 1999-12-31
EP0815126A1 (en) 1998-01-07
HRP960117B1 (en) 2001-06-30
CZ286297A3 (cs) 1998-02-18
HUP9801835A3 (en) 2000-05-29
HRP960117A2 (en) 1997-08-31
IL117395A0 (en) 1996-07-23
EA199700223A1 (ru) 1998-04-30
SK121297A3 (en) 1998-02-04
SK281899B6 (sk) 2001-09-11

Similar Documents

Publication Publication Date Title
IL116323A0 (en) Tachykinin antagonists their preparation and pharmaceutical compositions containing them
HUP9801433A3 (en) Glycoprotein iib/iiia antagonists, preparation and use thereof and pharmaceutical composition
PT832082E (pt) Derivados de n-heteroaril-piridinossulfonamidas e sua utilizacao como antagonistas de endotelina
DE69726015D1 (de) Pharmazeutische zusammensetzung enthaltend koenzym q-10
DE69618587D1 (de) Chinazoline und pharmazeutische zusammensetzungen
EE03680B1 (et) Asendatud püridiinid, nende kasutamine ja farmatseutilised kompositsioonid
DE69525148D1 (de) Pharmazeutische formulierung
AU7584396A (en) Spiro-piperidine derivatives and their use as tachykinin antagonists
DE69807420D1 (de) Pharmazeutische aerosolzusammensetzung
HK1030939A1 (en) Aroyl-piperazine derivatives, their preparation and their use as tachykinin antagonists
EE9600172A (et) Puriin-6-ooni derivaadid, nende valmistamismeetod, kasutamine ravimite valmistamiseks ja ravimid
BR9602915A (pt) Medicamentos uso e formulação farmacêutica
EE9700288A (et) Asatsükloalkaani derivaadid, nende valmistamine ja kasutamine ravis
EE9900034A (et) Arüültsükloalkaankarboksüülestrid, nende kasutamine, farmatseutilised kompositsioonid ja valmistamine
EE03618B1 (et) Bitsüklilised tahhükiniini antagonistid, nende valmistamine ja kasutamine ravimsegus
AU5650894A (en) Tachyquinine antagonists, their preparation and use in pharmaceutical formulations
EE03996B1 (et) Farmatseutilised kompositsioonid, nende valmistamismeetod ja kasutamine
FI941914A (fi) 2-amino-4-kinoliinidihydropyridiinejä, menetelmiä niiden valmistamiseksi ja niiden käyttö
FI941912A (fi) 3-kinolyylillä substituoidut dihydropyridiinit, menetelmä niiden valmistamiseksi ja niiden käyttö lääkeaineissa
DE69434210D1 (de) Pharmazeutische antacidzusammensetzung
EE200000207A (et) 8-asabitsüklo[3.2.1]oktaan-3-metaanamiini derivaadid, nende valmistamine ja terapeutiline kasutamine
BR9710568A (pt) Composi- o farmac-utica contendo um antagonista 5Hht2c e um antagonista d2
DE19681529D2 (de) Pharmazeutische Darreichungsform
DE69613966D1 (de) Pharmazeutische zusammensetzungen mit pektin
SI0815126T1 (en) Bicyclic tachykinins antagonists, preparation thereof and their use in pharmaceutical composition

Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20021231

KB4A Valid patent at the end of a year

Effective date: 20031231

KB4A Valid patent at the end of a year

Effective date: 20041231

KB4A Valid patent at the end of a year

Effective date: 20051231

KB4A Valid patent at the end of a year

Effective date: 20061231

KB4A Valid patent at the end of a year

Effective date: 20071231

KB4A Valid patent at the end of a year

Effective date: 20081231

KB4A Valid patent at the end of a year

Effective date: 20091231

KB4A Valid patent at the end of a year

Effective date: 20101231