EE200000207A - 8-asabitsüklo[3.2.1]oktaan-3-metaanamiini derivaadid, nende valmistamine ja terapeutiline kasutamine - Google Patents

8-asabitsüklo[3.2.1]oktaan-3-metaanamiini derivaadid, nende valmistamine ja terapeutiline kasutamine

Info

Publication number
EE200000207A
EE200000207A EEP200000207A EEP200000207A EE200000207A EE 200000207 A EE200000207 A EE 200000207A EE P200000207 A EEP200000207 A EE P200000207A EE P200000207 A EEP200000207 A EE P200000207A EE 200000207 A EE200000207 A EE 200000207A
Authority
EE
Estonia
Prior art keywords
azabicyclo
octane
preparation
therapeutic use
methanamine derivatives
Prior art date
Application number
EEP200000207A
Other languages
English (en)
Inventor
Marabout Benoit
Sevrin Mireille
George Pascal
Merly Jean-Pierre
de Peretti Dani�le
Roy Jocelyne
Machnik David
Original Assignee
Sanofi-Synthlabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9712583A external-priority patent/FR2769629B1/fr
Priority claimed from FR9712580A external-priority patent/FR2769628B1/fr
Application filed by Sanofi-Synthlabo filed Critical Sanofi-Synthlabo
Publication of EE200000207A publication Critical patent/EE200000207A/et
Publication of EE04347B1 publication Critical patent/EE04347B1/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
EEP200000207A 1997-10-09 1998-10-07 8-asabitsüklo[3.2.1]oktaan-3-metaanamiini derivaadid, neid sisaldav ravim ja farmatseutiline kompositsioon EE04347B1 (et)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9712583A FR2769629B1 (fr) 1997-10-09 1997-10-09 Derives de 8-azabicyclo[3.2.1]octane-3-methanamine, leur preparation et leur application en therapeutique
FR9712580A FR2769628B1 (fr) 1997-10-09 1997-10-09 Derives de n-(2,3-dihydro-1h-inden-2-yl)-n-propyl-8- azabicyclo[3.2.1.]octane-3-methanamine, leur preparation et leur application en therapeutique
PCT/FR1998/002137 WO1999019325A1 (fr) 1997-10-09 1998-10-07 Derives de 8-azabicyclo [3.2.1] octane-3-methanamine en tant que ligands des recepteurs de dopamine d2 et d3 et de serotonine 5ht1a et 5ht2

Publications (2)

Publication Number Publication Date
EE200000207A true EE200000207A (et) 2001-04-16
EE04347B1 EE04347B1 (et) 2004-08-16

Family

ID=26233854

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200000207A EE04347B1 (et) 1997-10-09 1998-10-07 8-asabitsüklo[3.2.1]oktaan-3-metaanamiini derivaadid, neid sisaldav ravim ja farmatseutiline kompositsioon

Country Status (31)

Country Link
US (1) US6221879B1 (et)
EP (1) EP1021442B1 (et)
JP (1) JP4505135B2 (et)
KR (1) KR20010015717A (et)
CN (1) CN1140526C (et)
AR (1) AR017300A1 (et)
AT (1) ATE212631T1 (et)
AU (1) AU746935B2 (et)
BG (1) BG64859B1 (et)
BR (1) BR9812752A (et)
CA (1) CA2305468C (et)
CO (1) CO5011097A1 (et)
CZ (1) CZ290679B6 (et)
DE (1) DE69803689T2 (et)
DK (1) DK1021442T3 (et)
EE (1) EE04347B1 (et)
ES (1) ES2171306T3 (et)
HK (1) HK1029108A1 (et)
HU (1) HUP0102086A3 (et)
IL (2) IL135520A0 (et)
NO (1) NO325170B1 (et)
NZ (1) NZ503829A (et)
PL (1) PL186998B1 (et)
PT (1) PT1021442E (et)
RU (1) RU2203281C2 (et)
SI (1) SI1021442T1 (et)
SK (1) SK283080B6 (et)
TR (1) TR200000942T2 (et)
TW (1) TW444014B (et)
UA (1) UA58476C2 (et)
WO (1) WO1999019325A1 (et)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6689806B1 (en) 1999-03-24 2004-02-10 Sugen, Inc. Indolinone compounds as kinase inhibitors
US6878733B1 (en) 1999-11-24 2005-04-12 Sugen, Inc. Formulations for pharmaceutical agents ionizable as free acids or free bases
ATE520659T1 (de) * 2004-10-14 2011-09-15 Abbott Gmbh & Co Kg Zur behandlung von auf die modulation des dopamin-d3-rezeptors ansprechenden erkrankungen geeignete azabicycloheptylverbindungen
BRPI0608353A2 (pt) 2005-02-17 2009-12-01 Wyeth Corp derivados de indol, benzotiofeno, benzofurano e indeno cicloalquilfundidos
KR101756495B1 (ko) 2010-03-11 2017-07-10 다이닛본 스미토모 세이야꾸 가부시끼가이샤 Ｎ-아실 시클릭 아민 유도체 또는 이의 의약상 허용되는 염
EP3230256B1 (en) * 2014-12-09 2019-11-13 Ezekiel Golan Alcoholic beverage substitutes
EP3705469A1 (en) 2014-12-09 2020-09-09 GOLAN, Ezekiel Binge behavior regulators
KR102128782B1 (ko) 2018-09-20 2020-07-01 한양대학교 에리카산학협력단 트로페인(Tropane) 알칼로이드 화합물 및 순차적 산화반응을 이용한 이의 제조방법

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL59004A0 (en) 1978-12-30 1980-03-31 Beecham Group Ltd Substituted benzamides their preparation and pharmaceutical compositions containing them
JPS5592384A (en) * 1978-12-30 1980-07-12 Beecham Group Ltd Compound having pharmacological activity
IL61642A0 (en) * 1979-12-20 1981-01-30 Beecham Group Ltd Aniline derivatives,their preparation and pharmalceutical compositions containing them
US4910302A (en) * 1988-12-19 1990-03-20 American Home Products Corporation Psychotropic polycyclic imides
FR2659323B1 (fr) * 1990-03-07 1992-06-12 Synthelabo Derives de 4-(aminomethyl) piperidine, leur preparation et leur application en therapeutique.
FR2681320B1 (fr) * 1991-09-12 1994-01-14 Synthelabo Derives de n-(4,7dimethoxyindan-2-yl)-1-(phenylcarbonyl)-n-propyl-piperidine-4-methanamine, leur preparation et leur application en therapeutique.
FR2681325B1 (fr) * 1991-09-16 1993-12-17 Fabre Medicament Pierre Derives de l'aminomethyl-4 piperidine, leur preparation et leur application en therapeutique.
DE4135474A1 (de) * 1991-10-28 1993-04-29 Bayer Ag 2-aminomethyl-chromane
FR2702211B1 (fr) * 1993-03-04 1995-06-02 Pf Medicament Nouveaux dérivés de la phénoxy-2 éthylamine, leur préparation et leur application en thérapeutique.

Also Published As

Publication number Publication date
PL339764A1 (en) 2001-01-02
EP1021442B1 (fr) 2002-01-30
EE04347B1 (et) 2004-08-16
CA2305468C (en) 2007-09-25
ATE212631T1 (de) 2002-02-15
SK283080B6 (sk) 2003-02-04
DK1021442T3 (da) 2002-05-13
IL135520A0 (en) 2001-05-20
CA2305468A1 (en) 1999-04-22
NZ503829A (en) 2002-03-28
DE69803689D1 (de) 2002-03-14
BG104309A (en) 2001-05-31
ES2171306T3 (es) 2002-09-01
UA58476C2 (uk) 2003-08-15
AR017300A1 (es) 2001-09-05
CN1140526C (zh) 2004-03-03
IL135520A (en) 2007-07-24
DE69803689T2 (de) 2002-10-10
JP2001519431A (ja) 2001-10-23
SI1021442T1 (en) 2002-08-31
NO325170B1 (no) 2008-02-11
TR200000942T2 (tr) 2000-09-21
KR20010015717A (ko) 2001-02-26
CN1281455A (zh) 2001-01-24
EP1021442A1 (fr) 2000-07-26
TW444014B (en) 2001-07-01
RU2203281C2 (ru) 2003-04-27
AU9446898A (en) 1999-05-03
PL186998B1 (pl) 2004-04-30
PT1021442E (pt) 2002-06-28
US6221879B1 (en) 2001-04-24
CZ20001278A3 (cs) 2000-07-12
BG64859B1 (bg) 2006-07-31
NO20001810L (no) 2000-06-09
CO5011097A1 (es) 2001-02-28
CZ290679B6 (cs) 2002-09-11
AU746935B2 (en) 2002-05-09
HK1029108A1 (en) 2001-03-23
HUP0102086A3 (en) 2002-09-30
NO20001810D0 (no) 2000-04-07
SK5042000A3 (en) 2001-03-12
BR9812752A (pt) 2000-08-29
JP4505135B2 (ja) 2010-07-21
WO1999019325A1 (fr) 1999-04-22
HUP0102086A2 (hu) 2001-12-28

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