FI956298A0 - 3-fenyyli-isokinolin-1(2H)-oneja, niiden valmistus ja terapeuttinen käyttö - Google Patents

3-fenyyli-isokinolin-1(2H)-oneja, niiden valmistus ja terapeuttinen käyttö

Info

Publication number
FI956298A0
FI956298A0 FI956298A FI956298A FI956298A0 FI 956298 A0 FI956298 A0 FI 956298A0 FI 956298 A FI956298 A FI 956298A FI 956298 A FI956298 A FI 956298A FI 956298 A0 FI956298 A0 FI 956298A0
Authority
FI
Finland
Prior art keywords
isoquinolin
ones
phenyl
preparation
therapeutic use
Prior art date
Application number
FI956298A
Other languages
English (en)
Swedish (sv)
Other versions
FI956298A (fi
Inventor
Mireille Sevrin
Benoit Marabout
Jacques Froissant
Catherine Guinot
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of FI956298A0 publication Critical patent/FI956298A0/fi
Publication of FI956298A publication Critical patent/FI956298A/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
FI956298A 1994-12-29 1995-12-28 3-fenyyli-isokinolin-1(2H)-oneja, niiden valmistus ja terapeuttinen käyttö FI956298A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9415837A FR2728900B1 (fr) 1994-12-29 1994-12-29 Derives de 3-phenylisoquinolein-1(2h)-one, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
FI956298A0 true FI956298A0 (fi) 1995-12-28
FI956298A FI956298A (fi) 1996-06-30

Family

ID=9470390

Family Applications (1)

Application Number Title Priority Date Filing Date
FI956298A FI956298A (fi) 1994-12-29 1995-12-28 3-fenyyli-isokinolin-1(2H)-oneja, niiden valmistus ja terapeuttinen käyttö

Country Status (22)

Country Link
US (1) US5665733A (fi)
EP (1) EP0719764B1 (fi)
JP (1) JPH08239365A (fi)
KR (1) KR960022472A (fi)
CN (1) CN1131150A (fi)
AR (1) AR002016A1 (fi)
AT (1) ATE172966T1 (fi)
AU (1) AU698595B2 (fi)
BR (1) BR9506106A (fi)
CA (1) CA2166234A1 (fi)
CO (1) CO4700298A1 (fi)
CZ (1) CZ348995A3 (fi)
DE (1) DE69505780D1 (fi)
FI (1) FI956298A (fi)
FR (1) FR2728900B1 (fi)
HU (1) HU215394B (fi)
IL (1) IL116590A0 (fi)
NO (1) NO955326L (fi)
NZ (1) NZ280765A (fi)
PL (1) PL312079A1 (fi)
SK (1) SK165795A3 (fi)
ZA (1) ZA9511046B (fi)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2750427B1 (fr) * 1996-06-28 1998-08-07 Synthelabo Derives de 1-oxo-1, 2-dihydroisoquinoleine-4-propanamide, leur preparation et leur application en therapeutique
FR2772758B1 (fr) * 1997-12-22 2000-02-04 Synthelabo Derives de 1-oxo-1,2-dihydroisoquinoleine-4-propanamide, leur preparation et leur application en therapeutique
WO2004058717A1 (en) * 2002-12-20 2004-07-15 X-Ceptor Therapeutics, Inc. Isoquinolinone derivatives and their use as therapeutic agents
GB0420722D0 (en) * 2004-09-17 2004-10-20 Addex Pharmaceuticals Sa Novel allosteric modulators
EP2064185B1 (en) * 2006-08-10 2011-06-08 Ferrer Internacional, S.A. 1h-quinolin-4-one compounds, with affinity for the gaba receptor, processes, uses and compositions
EP1886996A1 (en) * 2006-08-10 2008-02-13 Ferrer Internacional, S.A. 1H-Quinolin-4-one compounds, with affinity for the GABA receptor, processes, uses and compositions
US8741917B2 (en) 2009-01-15 2014-06-03 Rutgers, The State University Of New Jersey Benzo [C] phenanthridines as antimicrobial agents
CA2760526A1 (en) * 2009-04-30 2010-11-04 Rutgers, The State University Of New Jersey Antimicrobial agents
FR2956816B1 (fr) * 2010-03-01 2012-05-18 Univ Joseph Fourier Utilisation de quinolones pour la preparation de medicaments, nouvelles quinolones et leur procede de synthese
CA2810162A1 (en) 2010-06-09 2011-12-15 Rutgers, The State University Of New Jersey Antimicrobial agents
US9102617B2 (en) 2010-06-25 2015-08-11 Rutgers, The State University Of New Jersey Antimicrobial agents
WO2013106756A2 (en) 2012-01-13 2013-07-18 Rutgers, The State University Of New Jersey Antimicrobial agents
EP2828245A1 (en) 2012-03-21 2015-01-28 Rutgers, The State University of New Jersey Antimicrobial agents
US9458150B2 (en) 2013-11-08 2016-10-04 Rutgers, The State University Of New Jersey Antimicrobial agents
CA3015768A1 (en) 2016-02-25 2017-08-31 Taxis Pharmaceuticals, Inc. Synthetic processes and intermediates
CN110891566B (zh) 2017-03-30 2023-12-19 塔克西斯医药股份有限公司 合成方法和合成中间体
TW202202495A (zh) * 2020-03-26 2022-01-16 匈牙利商羅特格登公司 作為gamma-胺基丁酸A受體次單元alpha 5受體調節劑之㖠啶及吡啶并〔3,4-c〕嗒𠯤衍生物
WO2021191837A1 (en) * 2020-03-26 2021-09-30 Richter Gedeon Nyrt. 1,3-dihydro-2h-pyrrolo[3,4-c]pyridine derivatives as gabaa α5 receptor modulators

Also Published As

Publication number Publication date
ATE172966T1 (de) 1998-11-15
ZA9511046B (en) 1996-07-11
CA2166234A1 (en) 1996-06-30
IL116590A0 (en) 1996-03-31
CN1131150A (zh) 1996-09-18
US5665733A (en) 1997-09-09
EP0719764B1 (fr) 1998-11-04
NO955326D0 (no) 1995-12-28
HU215394B (hu) 1998-12-28
AU4071295A (en) 1996-07-04
KR960022472A (ko) 1996-07-18
HUT74187A (en) 1996-11-28
FR2728900B1 (fr) 1997-01-31
DE69505780D1 (de) 1998-12-10
AR002016A1 (es) 1998-01-07
CO4700298A1 (es) 1998-12-29
NO955326L (no) 1996-07-01
FI956298A (fi) 1996-06-30
SK165795A3 (en) 1996-07-03
FR2728900A1 (fr) 1996-07-05
EP0719764A1 (fr) 1996-07-03
BR9506106A (pt) 1997-12-23
NZ280765A (en) 1996-08-27
JPH08239365A (ja) 1996-09-17
PL312079A1 (en) 1996-07-08
AU698595B2 (en) 1998-11-05
HU9503848D0 (en) 1996-02-28
CZ348995A3 (en) 1996-07-17

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