NO955326L - Isokinolinderivater, fremgangsmåte for deres fremstilling og terapeutiske anvendelse - Google Patents
Isokinolinderivater, fremgangsmåte for deres fremstilling og terapeutiske anvendelseInfo
- Publication number
- NO955326L NO955326L NO955326A NO955326A NO955326L NO 955326 L NO955326 L NO 955326L NO 955326 A NO955326 A NO 955326A NO 955326 A NO955326 A NO 955326A NO 955326 L NO955326 L NO 955326L
- Authority
- NO
- Norway
- Prior art keywords
- group
- therapeutic use
- preparation
- isoquinoline derivatives
- alkyl group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Abstract
Forbindelser med generell formel (I) (D hvor X representerer et hydrogenatom, et halogenatom, en trifluormetylgruppe, en alkylgruppe eller en eller to alkoksy- grupper, Y representerer et hydrogenatom, et halogenatom, en alkylgruppe eller en alkoksygruppe, RL representerer en alkyl- gruppe og R representerer en hydroksygruppe, en metoksygruppe, en etoksygruppe eller en gruppe med generell formel NR2R3 hvor R2 og R3 hver representerer et hydrogenatom eller en alkylgruppe. Forbindelsene har terapeutisk anvendelse.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9415837A FR2728900B1 (fr) | 1994-12-29 | 1994-12-29 | Derives de 3-phenylisoquinolein-1(2h)-one, leur preparation et leur application en therapeutique |
Publications (2)
Publication Number | Publication Date |
---|---|
NO955326D0 NO955326D0 (no) | 1995-12-28 |
NO955326L true NO955326L (no) | 1996-07-01 |
Family
ID=9470390
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO955326A NO955326L (no) | 1994-12-29 | 1995-12-28 | Isokinolinderivater, fremgangsmåte for deres fremstilling og terapeutiske anvendelse |
Country Status (22)
Country | Link |
---|---|
US (1) | US5665733A (no) |
EP (1) | EP0719764B1 (no) |
JP (1) | JPH08239365A (no) |
KR (1) | KR960022472A (no) |
CN (1) | CN1131150A (no) |
AR (1) | AR002016A1 (no) |
AT (1) | ATE172966T1 (no) |
AU (1) | AU698595B2 (no) |
BR (1) | BR9506106A (no) |
CA (1) | CA2166234A1 (no) |
CO (1) | CO4700298A1 (no) |
CZ (1) | CZ348995A3 (no) |
DE (1) | DE69505780D1 (no) |
FI (1) | FI956298A (no) |
FR (1) | FR2728900B1 (no) |
HU (1) | HU215394B (no) |
IL (1) | IL116590A0 (no) |
NO (1) | NO955326L (no) |
NZ (1) | NZ280765A (no) |
PL (1) | PL312079A1 (no) |
SK (1) | SK165795A3 (no) |
ZA (1) | ZA9511046B (no) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2750427B1 (fr) * | 1996-06-28 | 1998-08-07 | Synthelabo | Derives de 1-oxo-1, 2-dihydroisoquinoleine-4-propanamide, leur preparation et leur application en therapeutique |
FR2772758B1 (fr) * | 1997-12-22 | 2000-02-04 | Synthelabo | Derives de 1-oxo-1,2-dihydroisoquinoleine-4-propanamide, leur preparation et leur application en therapeutique |
DE60335911D1 (de) * | 2002-12-20 | 2011-03-10 | Daiichi Sankyo Co Ltd | Isochinolinonderivate und deren verwendung als medikamente |
GB0420722D0 (en) * | 2004-09-17 | 2004-10-20 | Addex Pharmaceuticals Sa | Novel allosteric modulators |
PL2064185T3 (pl) * | 2006-08-10 | 2011-11-30 | Ferrer Int | Związki 1H-chinolin-4-onowe z powinowactwem do receptora GABA, sposoby wytwarzania, zastosowanie i kompozycje |
EP1886996A1 (en) * | 2006-08-10 | 2008-02-13 | Ferrer Internacional, S.A. | 1H-Quinolin-4-one compounds, with affinity for the GABA receptor, processes, uses and compositions |
WO2010083436A1 (en) | 2009-01-15 | 2010-07-22 | Rutgers, The State University Of New Jersey | Benzo [c] phenanthridines as antimicrobial agents |
US20120059026A1 (en) | 2009-04-30 | 2012-03-08 | University Of Medicine And Dentistry Of New Jersey | Antimicrobial agents |
FR2956816B1 (fr) * | 2010-03-01 | 2012-05-18 | Univ Joseph Fourier | Utilisation de quinolones pour la preparation de medicaments, nouvelles quinolones et leur procede de synthese |
US8933096B2 (en) | 2010-06-09 | 2015-01-13 | Rugers, The State University of New Jersey | Antimicrobial agents |
WO2011163610A2 (en) | 2010-06-25 | 2011-12-29 | Rutgers, The State University Of New Jersey | Antimicrobial agents |
WO2013106756A2 (en) | 2012-01-13 | 2013-07-18 | Rutgers, The State University Of New Jersey | Antimicrobial agents |
AU2013235038A1 (en) | 2012-03-21 | 2014-10-09 | Malvika Kaul | Antimicrobial agents |
US9458150B2 (en) | 2013-11-08 | 2016-10-04 | Rutgers, The State University Of New Jersey | Antimicrobial agents |
JP2019507801A (ja) | 2016-02-25 | 2019-03-22 | タクシス ファーマシューティカルズ, インコーポレイテッド | 合成プロセス及び中間体 |
CA3058183A1 (en) | 2017-03-30 | 2018-10-04 | Taxis Pharmaceuticals, Inc. | Synthetic processes and synthetic intermediates |
TW202202495A (zh) * | 2020-03-26 | 2022-01-16 | 匈牙利商羅特格登公司 | 作為gamma-胺基丁酸A受體次單元alpha 5受體調節劑之㖠啶及吡啶并〔3,4-c〕嗒𠯤衍生物 |
US20240043418A1 (en) * | 2020-03-26 | 2024-02-08 | Richter Gedeon Nyrt. | 1,3-dihydro-2h-pyrrolo[3,4-c]pyridine derivatives as gabaa a5 receptor modulators |
-
1994
- 1994-12-29 FR FR9415837A patent/FR2728900B1/fr not_active Expired - Fee Related
-
1995
- 1995-12-18 AT AT95402842T patent/ATE172966T1/de not_active IP Right Cessation
- 1995-12-18 EP EP95402842A patent/EP0719764B1/fr not_active Expired - Lifetime
- 1995-12-18 DE DE69505780T patent/DE69505780D1/de not_active Expired - Lifetime
- 1995-12-21 NZ NZ280765A patent/NZ280765A/en unknown
- 1995-12-27 AR ARP950100767A patent/AR002016A1/es unknown
- 1995-12-27 JP JP7340607A patent/JPH08239365A/ja active Pending
- 1995-12-28 IL IL11659095A patent/IL116590A0/xx unknown
- 1995-12-28 BR BR9506106A patent/BR9506106A/pt not_active Application Discontinuation
- 1995-12-28 KR KR1019950061341A patent/KR960022472A/ko not_active Application Discontinuation
- 1995-12-28 NO NO955326A patent/NO955326L/no unknown
- 1995-12-28 HU HU9503848A patent/HU215394B/hu not_active IP Right Cessation
- 1995-12-28 SK SK1657-95A patent/SK165795A3/sk unknown
- 1995-12-28 CA CA002166234A patent/CA2166234A1/en not_active Abandoned
- 1995-12-28 US US08/579,677 patent/US5665733A/en not_active Expired - Fee Related
- 1995-12-28 FI FI956298A patent/FI956298A/fi not_active Application Discontinuation
- 1995-12-28 PL PL95312079A patent/PL312079A1/xx unknown
- 1995-12-28 ZA ZA9511046A patent/ZA9511046B/xx unknown
- 1995-12-28 CO CO95062144A patent/CO4700298A1/es unknown
- 1995-12-28 CN CN95120638A patent/CN1131150A/zh active Pending
- 1995-12-28 CZ CZ953489A patent/CZ348995A3/cs unknown
- 1995-12-28 AU AU40712/95A patent/AU698595B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
PL312079A1 (en) | 1996-07-08 |
FR2728900B1 (fr) | 1997-01-31 |
SK165795A3 (en) | 1996-07-03 |
BR9506106A (pt) | 1997-12-23 |
HU9503848D0 (en) | 1996-02-28 |
DE69505780D1 (de) | 1998-12-10 |
CA2166234A1 (en) | 1996-06-30 |
AR002016A1 (es) | 1998-01-07 |
US5665733A (en) | 1997-09-09 |
KR960022472A (ko) | 1996-07-18 |
NZ280765A (en) | 1996-08-27 |
ZA9511046B (en) | 1996-07-11 |
HU215394B (hu) | 1998-12-28 |
ATE172966T1 (de) | 1998-11-15 |
AU4071295A (en) | 1996-07-04 |
HUT74187A (en) | 1996-11-28 |
IL116590A0 (en) | 1996-03-31 |
EP0719764A1 (fr) | 1996-07-03 |
FR2728900A1 (fr) | 1996-07-05 |
AU698595B2 (en) | 1998-11-05 |
CO4700298A1 (es) | 1998-12-29 |
EP0719764B1 (fr) | 1998-11-04 |
CZ348995A3 (en) | 1996-07-17 |
FI956298A (fi) | 1996-06-30 |
NO955326D0 (no) | 1995-12-28 |
FI956298A0 (fi) | 1995-12-28 |
JPH08239365A (ja) | 1996-09-17 |
CN1131150A (zh) | 1996-09-18 |
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