ES8506629A1 - Un procedimiento para preparar derivados de piridina - Google Patents
Un procedimiento para preparar derivados de piridinaInfo
- Publication number
- ES8506629A1 ES8506629A1 ES528309A ES528309A ES8506629A1 ES 8506629 A1 ES8506629 A1 ES 8506629A1 ES 528309 A ES528309 A ES 528309A ES 528309 A ES528309 A ES 528309A ES 8506629 A1 ES8506629 A1 ES 8506629A1
- Authority
- ES
- Spain
- Prior art keywords
- optionally substituted
- alkyl
- formula
- alkoxy
- yes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Abstract
PROCEDIMIENTO DE PREPARACION DE COMPUESTOS DE FORMULA (I), DONDE R1 Y R2, IGUALES O DIFERENTES, SON HIDROGENO, ALQUILO, ALCOXI O HALOGENO; R3 ES FENILO, OPCIONALMENTE SUSTITUIDO; R4 ES UN GRUPO CICLICO; A SE SITUA ENTRE 1 Y 6; Y B ENTRE 2 Y 4.POR REACCION DE UN COMPUESTO DE FORMULA (II) DONDE R1, R2, R3, A Y B SON LOS INDICADOS, CON DIFERENTES COMPUESTOS CICLICOS SEGUN EL VALO DE R4. LA TEMPERATURA TAMBIEN DEPENDE DE LOS GRUPOS DE REACTIVOS, SITUANDOSE ENTRE 120JC Y 140JC, SIN DISOLVENTE, EN LA MAYOR PARTE DE LOS CASOS, O EN VALORES MAS ELEVADOS SI SE EMPLEA DISOLVENTE.DE APLICACION COMO SUSTANCIAQS ANTAGONISTAS H1 DE LA HISTAMINA.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8236637 | 1982-12-23 | ||
GB838322349A GB8322349D0 (en) | 1983-08-19 | 1983-08-19 | Pyridine derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
ES528309A0 ES528309A0 (es) | 1985-08-01 |
ES8506629A1 true ES8506629A1 (es) | 1985-08-01 |
Family
ID=26284767
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES528309A Expired ES8506629A1 (es) | 1982-12-23 | 1983-12-22 | Un procedimiento para preparar derivados de piridina |
Country Status (14)
Country | Link |
---|---|
US (3) | US4532246A (es) |
EP (1) | EP0112704B1 (es) |
AU (1) | AU2274783A (es) |
DE (1) | DE3374007D1 (es) |
DK (1) | DK592183A (es) |
ES (1) | ES8506629A1 (es) |
FI (1) | FI834735A (es) |
GR (1) | GR79740B (es) |
IL (1) | IL70497A0 (es) |
JO (1) | JO1279B1 (es) |
NO (1) | NO834778L (es) |
NZ (1) | NZ206636A (es) |
PT (1) | PT77855B (es) |
ZW (1) | ZW27383A1 (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2222083A (en) * | 1982-12-14 | 1984-06-21 | Smith Kline & French Laboratories Limited | Pyridine derivatives |
EP0112707B1 (en) * | 1982-12-23 | 1987-11-04 | Smith Kline & French Laboratories Limited | Aminopyrimidinone derivatives as histamine h1-antagonists |
CA1275097A (en) * | 1984-10-02 | 1990-10-09 | Fujio Nohara | Pyridyloxy derivatives |
US4728648A (en) * | 1985-02-09 | 1988-03-01 | Smith Kline & French Laboratories Limited | Histamine antagonist triadiazole derivatives, compositions, and method of use therefor |
GB8509277D0 (en) * | 1985-04-11 | 1985-05-15 | Smith Kline French Lab | Pyridine derivatives |
GB8509276D0 (en) * | 1985-04-11 | 1985-05-15 | Smith Kline French Lab | Pyridine derivatives |
CA1286297C (en) * | 1985-06-13 | 1991-07-16 | George S. Sach | Pyridine derivatives |
GB8610867D0 (en) * | 1986-05-02 | 1986-06-11 | Smith Kline French Lab | 3-hydroxypyridines |
US5872139A (en) * | 1996-06-17 | 1999-02-16 | American Home Products Corporation | Heterocyclymethylamino derivatives of cyclobutene-3,4-diones |
US6489344B1 (en) | 1998-06-19 | 2002-12-03 | Chiron Corporation | Inhibitors of glycogen synthase kinase 3 |
US7045519B2 (en) * | 1998-06-19 | 2006-05-16 | Chiron Corporation | Inhibitors of glycogen synthase kinase 3 |
MXPA05003867A (es) * | 2002-10-09 | 2005-11-23 | Schering Corp | Tiadiazoldioxidos y tiadiazoloxidos como ligandos de receptor cxc-y cc-quimiocina. |
TW200528450A (en) * | 2003-12-19 | 2005-09-01 | Schering Corp | Thiadiazoles as cxc-and cc-chemokine receptor ligands |
JP4851943B2 (ja) * | 2003-12-22 | 2012-01-11 | シェーリング コーポレイション | Cxc−ケモカインレセプターリガンドおよびcc−ケモカインレセプターリガンドとしてのイソチアゾールジオキシド |
WO2007002764A2 (en) * | 2005-06-29 | 2007-01-04 | Schering Corporation | Di-substituted oxadiazoles as cxc-chemokine receptor ligands |
WO2007005403A1 (en) * | 2005-06-29 | 2007-01-11 | Schering Corporation | 5,6-di-substituted oxadiazolopyrazines and thiadiazolopyrazines as cxc-chemokine receptor ligands |
EP2440527A1 (en) * | 2009-06-09 | 2012-04-18 | Topo Target A/S | Pyridinyl derivatives as inhibitors of enzyme nicotinamide phosphoribosyltransferase |
CN111349014A (zh) * | 2020-03-30 | 2020-06-30 | 绵阳达高特新材料有限公司 | 一种方酸甲胺甲酯的制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3535328A (en) * | 1967-09-01 | 1970-10-20 | Exxon Research Engineering Co | Certain substituted aminothioethoxy pyridines |
GB1419994A (en) * | 1973-05-03 | 1976-01-07 | Smith Kline French Lab | Heterocyclicalkylaminotheterocyclic compounds methods for their preparation and compositions comprising them |
GB1563090A (en) * | 1975-07-31 | 1980-03-19 | Smith Kline French Lab | Cyclobutene-diones |
US4120968A (en) * | 1975-07-31 | 1978-10-17 | Smith Kline & French Laboratories Limited | Heterocyclic alkylaminocyclobutenediones |
US4255428A (en) * | 1979-03-24 | 1981-03-10 | Smith Kline & French Laboratories Limited | 5-(Hydroxypyridylalkyl)-4-pyrimidones |
EP0040696B1 (en) * | 1980-04-30 | 1986-08-27 | Merck & Co. Inc. | Aminothiadiazoles as gastric secretion inhibitors |
US4394508A (en) * | 1980-06-07 | 1983-07-19 | Bristol-Myers Company | Chemical compounds |
-
1983
- 1983-12-19 EP EP83307708A patent/EP0112704B1/en not_active Expired
- 1983-12-19 PT PT77855A patent/PT77855B/pt unknown
- 1983-12-19 DE DE8383307708T patent/DE3374007D1/de not_active Expired
- 1983-12-19 JO JO19831279A patent/JO1279B1/en active
- 1983-12-20 NZ NZ206636A patent/NZ206636A/xx unknown
- 1983-12-20 ZW ZW273/83A patent/ZW27383A1/xx unknown
- 1983-12-20 IL IL70497A patent/IL70497A0/xx unknown
- 1983-12-20 US US06/563,496 patent/US4532246A/en not_active Expired - Fee Related
- 1983-12-21 AU AU22747/83A patent/AU2274783A/en not_active Abandoned
- 1983-12-22 FI FI834735A patent/FI834735A/fi not_active Application Discontinuation
- 1983-12-22 NO NO834778A patent/NO834778L/no unknown
- 1983-12-22 GR GR73335A patent/GR79740B/el unknown
- 1983-12-22 ES ES528309A patent/ES8506629A1/es not_active Expired
- 1983-12-22 DK DK592183A patent/DK592183A/da not_active Application Discontinuation
-
1985
- 1985-05-17 US US06/735,036 patent/US4607106A/en not_active Expired - Fee Related
-
1986
- 1986-06-19 US US06/876,049 patent/US4659725A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0112704A3 (en) | 1985-08-28 |
NZ206636A (en) | 1985-07-31 |
IL70497A0 (en) | 1984-03-30 |
FI834735A0 (fi) | 1983-12-22 |
FI834735A (fi) | 1984-06-24 |
DK592183A (da) | 1984-06-24 |
EP0112704A2 (en) | 1984-07-04 |
DE3374007D1 (en) | 1987-11-12 |
US4532246A (en) | 1985-07-30 |
JO1279B1 (en) | 1985-04-20 |
PT77855A (en) | 1984-01-01 |
GR79740B (es) | 1984-10-31 |
US4659725A (en) | 1987-04-21 |
EP0112704B1 (en) | 1987-10-07 |
ES528309A0 (es) | 1985-08-01 |
NO834778L (no) | 1984-06-25 |
AU2274783A (en) | 1984-06-28 |
US4607106A (en) | 1986-08-19 |
PT77855B (en) | 1986-04-16 |
ZW27383A1 (en) | 1985-07-24 |
DK592183D0 (da) | 1983-12-22 |
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