ES8504771A1 - Un procedimiento para preparar derivados de piridina - Google Patents
Un procedimiento para preparar derivados de piridinaInfo
- Publication number
- ES8504771A1 ES8504771A1 ES528310A ES528310A ES8504771A1 ES 8504771 A1 ES8504771 A1 ES 8504771A1 ES 528310 A ES528310 A ES 528310A ES 528310 A ES528310 A ES 528310A ES 8504771 A1 ES8504771 A1 ES 8504771A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- pyridyl
- optionally substituted
- oxo
- alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Abstract
PROCEDIMIENTO PARA PREPARAR DERIVADOS DE PIRIDINA.COMPRENDE: A) HACER REACCIONAR A UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III), PARA OBTENER UN COMPUESTO (I) CON UN GRUPO PROTECTOR DE HIDROXI COMO METOXIMETILO, METILTIOMETILO Y OTROS, EN R; Y B) HIDROLIZAR EN MEDIO ACIDO O BASICO A (I), PARA SEPARAR EL GRUPO PROTECTOR DE HIDROXI Y OBTENER UN COMPUESTO DE FORMULA (I) Y SUS SALES FARMACEUTICAMENTE ACEPTABLES. SIENDO: R Y R, H, ALQUILO DE C 1 A 6 Y OTROS; R ALQUILO DE C 1 A 6, CICLOALQUILO DE C 3 A 8 Y OTROS; R Y R, H, METILENDIOXI Y OTROS; R UN GRUPO DESPLAZABLE CON AMINA; A, 2, 3 O 4 Y B, 1, 2, 3, 4, 5 O 6.SE UTILIZAN COMO ANTAGONISTAS DE HISTAMINA H1.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8236638 | 1982-12-23 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8504771A1 true ES8504771A1 (es) | 1985-05-01 |
ES528310A0 ES528310A0 (es) | 1985-05-01 |
Family
ID=10535202
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES528310A Granted ES528310A0 (es) | 1982-12-23 | 1983-12-22 | Un procedimiento para preparar derivados de piridina |
Country Status (15)
Country | Link |
---|---|
US (1) | US4547506A (es) |
EP (1) | EP0113572B1 (es) |
JP (1) | JPS59130285A (es) |
KR (1) | KR840006992A (es) |
AU (1) | AU2274683A (es) |
DE (1) | DE3375574D1 (es) |
DK (1) | DK584683A (es) |
ES (1) | ES528310A0 (es) |
FI (1) | FI834736A (es) |
GR (1) | GR79735B (es) |
IL (1) | IL70496A0 (es) |
NO (1) | NO834777L (es) |
PT (1) | PT77856B (es) |
ZA (1) | ZA839529B (es) |
ZW (1) | ZW27483A1 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0112707B1 (en) * | 1982-12-23 | 1987-11-04 | Smith Kline & French Laboratories Limited | Aminopyrimidinone derivatives as histamine h1-antagonists |
CA1286297C (en) * | 1985-06-13 | 1991-07-16 | George S. Sach | Pyridine derivatives |
GB8601816D0 (en) * | 1986-01-25 | 1986-02-26 | Smith Kline French Lab | Pyridine derivatives |
ZA9756B (en) * | 1996-01-16 | 1997-07-17 | Warner Lambert Co | Process for preparing 4,6-disubstituted pyrido[3,4-d]-pyrimidines |
US7426961B2 (en) * | 2002-09-03 | 2008-09-23 | Bj Services Company | Method of treating subterranean formations with porous particulate materials |
US7045519B2 (en) | 1998-06-19 | 2006-05-16 | Chiron Corporation | Inhibitors of glycogen synthase kinase 3 |
JP4533534B2 (ja) | 1998-06-19 | 2010-09-01 | ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド | グリコーゲンシンターゼキナーゼ3のインヒビター |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3535328A (en) * | 1967-09-01 | 1970-10-20 | Exxon Research Engineering Co | Certain substituted aminothioethoxy pyridines |
GB1419994A (en) * | 1973-05-03 | 1976-01-07 | Smith Kline French Lab | Heterocyclicalkylaminotheterocyclic compounds methods for their preparation and compositions comprising them |
US4218452A (en) * | 1975-10-02 | 1980-08-19 | Smith Kline & French Laboratories Limited | Substituted 4-pyrimidone compounds, compositions and methods of use |
US4154834A (en) * | 1975-12-29 | 1979-05-15 | Smith Kline & French Laboratories Limited | Substituted isocytosines having histamine H2 -antagonist activity |
US4227000A (en) * | 1978-04-11 | 1980-10-07 | Smith Kline & French Laboratories Limited | Intermediates in the process for making histamine antagonists |
US4255428A (en) * | 1979-03-24 | 1981-03-10 | Smith Kline & French Laboratories Limited | 5-(Hydroxypyridylalkyl)-4-pyrimidones |
ZW21281A1 (en) * | 1980-10-01 | 1981-11-18 | Smith Kline French Lab | Amine derivatives |
-
1983
- 1983-12-19 PT PT77856A patent/PT77856B/pt unknown
- 1983-12-19 EP EP83307721A patent/EP0113572B1/en not_active Expired
- 1983-12-19 DK DK584683A patent/DK584683A/da not_active Application Discontinuation
- 1983-12-19 DE DE8383307721T patent/DE3375574D1/de not_active Expired
- 1983-12-20 US US06/563,495 patent/US4547506A/en not_active Expired - Fee Related
- 1983-12-20 ZW ZW274/83A patent/ZW27483A1/xx unknown
- 1983-12-20 IL IL70496A patent/IL70496A0/xx unknown
- 1983-12-21 AU AU22746/83A patent/AU2274683A/en not_active Abandoned
- 1983-12-22 ES ES528310A patent/ES528310A0/es active Granted
- 1983-12-22 JP JP58243047A patent/JPS59130285A/ja active Pending
- 1983-12-22 NO NO834777A patent/NO834777L/no unknown
- 1983-12-22 FI FI834736A patent/FI834736A/fi not_active Application Discontinuation
- 1983-12-22 GR GR73337A patent/GR79735B/el unknown
- 1983-12-22 ZA ZA839529A patent/ZA839529B/xx unknown
- 1983-12-23 KR KR1019830006151A patent/KR840006992A/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
PT77856B (en) | 1986-04-16 |
JPS59130285A (ja) | 1984-07-26 |
NO834777L (no) | 1984-06-25 |
AU2274683A (en) | 1984-06-28 |
DK584683D0 (da) | 1983-12-19 |
ES528310A0 (es) | 1985-05-01 |
DE3375574D1 (en) | 1988-03-10 |
PT77856A (en) | 1984-01-01 |
KR840006992A (ko) | 1984-12-04 |
EP0113572B1 (en) | 1988-02-03 |
FI834736A (fi) | 1984-06-24 |
ZW27483A1 (en) | 1985-04-17 |
ZA839529B (en) | 1984-08-29 |
EP0113572A2 (en) | 1984-07-18 |
GR79735B (es) | 1984-10-31 |
US4547506A (en) | 1985-10-15 |
FI834736A0 (fi) | 1983-12-22 |
EP0113572A3 (en) | 1985-08-28 |
IL70496A0 (en) | 1984-03-30 |
DK584683A (da) | 1984-06-24 |
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