ES8704478A1 - Procedimiento para la obtencion de derivados de piridina - Google Patents

Procedimiento para la obtencion de derivados de piridina

Info

Publication number
ES8704478A1
ES8704478A1 ES548013A ES548013A ES8704478A1 ES 8704478 A1 ES8704478 A1 ES 8704478A1 ES 548013 A ES548013 A ES 548013A ES 548013 A ES548013 A ES 548013A ES 8704478 A1 ES8704478 A1 ES 8704478A1
Authority
ES
Spain
Prior art keywords
pyridine derivatives
actions
alkyl
alkoxy
suppressant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES548013A
Other languages
English (en)
Other versions
ES548013A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of ES8704478A1 publication Critical patent/ES8704478A1/es
Publication of ES548013A0 publication Critical patent/ES548013A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Automatic Cycles, And Cycles In General (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE PIRIDINA, DE FORMULA (I), Y DE SUS SALES. COMPRENDE LA REACCION DE UN COMPUESTO DE FORMULA PY-A-X1 CON UN COMPUESTO DE FORMULA X2-CH2 CH2-CR2FCH-CH2-X3, PARA OBTENER UN COMPUESTO DE FORMULA (I), EN LAS QUE R1, R2, PY-X1, X2 Y X3 PUEDEN SER VARIOS TIPOS DE RADICALES, A REPRESENTA -CNH2N-, Y N VALE 1-3. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACEUTICAS COMO SEDANTES, TRANQUILIZANTES, NEUROLEPTICOS Y ANTIDEPRESIVOS.
ES548013A 1984-10-19 1985-10-18 Procedimiento para la obtencion de derivados de piridina Expired ES8704478A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843438394 DE3438394A1 (de) 1984-10-19 1984-10-19 Pyridinderivate

Publications (2)

Publication Number Publication Date
ES8704478A1 true ES8704478A1 (es) 1987-04-01
ES548013A0 ES548013A0 (es) 1987-04-01

Family

ID=6248339

Family Applications (1)

Application Number Title Priority Date Filing Date
ES548013A Expired ES8704478A1 (es) 1984-10-19 1985-10-18 Procedimiento para la obtencion de derivados de piridina

Country Status (10)

Country Link
US (2) US4665187A (es)
EP (1) EP0180794B1 (es)
JP (1) JPS61100579A (es)
AT (1) ATE43591T1 (es)
AU (1) AU583308B2 (es)
CA (1) CA1269384A (es)
DE (2) DE3438394A1 (es)
ES (1) ES8704478A1 (es)
HU (1) HU195652B (es)
ZA (1) ZA858041B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3609142A1 (de) * 1986-03-19 1987-09-24 Merck Patent Gmbh Pyridinderivate
US5118691A (en) * 1990-09-20 1992-06-02 Warner-Lambert Co. Substituted tetrahydropyridines as central nervous system agents
US5187280A (en) * 1990-09-20 1993-02-16 Warner-Lambert Company Substituted tetrahydropyridines and their use as central nervous system agents
US5045550A (en) * 1990-09-20 1991-09-03 Warner-Lambert Co. Substituted tetrahydropyridines as central nervous system agents
DE19612890C2 (de) * 1996-03-30 2003-12-18 Diehl Stiftung & Co Mörsergeschoß
WO2001053288A1 (fr) 2000-01-20 2001-07-26 Eisai Co., Ltd. Nouveaux composes de piperidine et medicaments contenant ces composes
EP1724253A3 (en) * 2005-05-10 2009-11-04 Ajinomoto Co., Inc. Production method of optically active diphenylalanine compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3125488A (en) * 1964-03-17 Method of inducing analgesia by
US3546236A (en) * 1968-10-15 1970-12-08 Smithkline Corp 1 - (benzoheterocyclic cyclopropylmethyl) - 4 - phenyl - 1,2,5,6 - tetrahydropyridines
FR2501682A1 (fr) * 1981-03-11 1982-09-17 Sanofi Sa Trifluoromethylphenylpyridines a activite anorexigene, un procede de preparation et compositions pharmaceutiques en contenant
FR2501506A1 (fr) * 1981-03-11 1982-09-17 Sanofi Sa Compositions pharmaceutiques a action anorexigene contenant des derives de la tetrahydropyridine
FR2531707A1 (fr) * 1982-08-16 1984-02-17 Midy Spa Trifluoromethylphenyltetrahydropyridines substituees a activite anorexigene, un procede de preparation et compositions pharmaceutiques

Also Published As

Publication number Publication date
AU583308B2 (en) 1989-04-27
DE3438394A1 (de) 1986-04-30
ATE43591T1 (de) 1989-06-15
US4665187A (en) 1987-05-12
ZA858041B (en) 1986-06-25
EP0180794B1 (de) 1989-05-31
JPS61100579A (ja) 1986-05-19
AU4873785A (en) 1986-04-24
HUT39741A (en) 1986-10-29
HU195652B (en) 1988-06-28
EP0180794A1 (de) 1986-05-14
CA1269384A (en) 1990-05-22
DE3570668D1 (en) 1989-07-06
US4760082A (en) 1988-07-26
ES548013A0 (es) 1987-04-01

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Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960506