EE9900147A - Oksadiasoolid, nende saamismeetodid ja kasutamine ravimitena - Google Patents

Oksadiasoolid, nende saamismeetodid ja kasutamine ravimitena

Info

Publication number
EE9900147A
EE9900147A EEP199900147A EE9900147A EE9900147A EE 9900147 A EE9900147 A EE 9900147A EE P199900147 A EEP199900147 A EE P199900147A EE 9900147 A EE9900147 A EE 9900147A EE 9900147 A EE9900147 A EE 9900147A
Authority
EE
Estonia
Prior art keywords
oxadiazoles
pharmaceuticals
preparation
methods
Prior art date
Application number
EEP199900147A
Other languages
English (en)
Inventor
Brenner Michael
Maier Roland
Wienrich Marion
Weiser Thomas
Palluk Rainer
Bechtel Wolf-Dietrich
Sagrada Angelo
Ensinger Helmut
Pschorn Uwe
Cesana Raffaele
Original Assignee
Boehringer Ingelheim Pharma Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma Kg filed Critical Boehringer Ingelheim Pharma Kg
Publication of EE9900147A publication Critical patent/EE9900147A/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
EEP199900147A 1996-10-18 1997-10-15 Oksadiasoolid, nende saamismeetodid ja kasutamine ravimitena EE9900147A (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19643037A DE19643037A1 (de) 1996-10-18 1996-10-18 Neue Oxadiazole, Verfahren zu ihrer Herstellung sowie deren Verwendung als Arzneimittel
PCT/EP1997/005693 WO1998017652A1 (de) 1996-10-18 1997-10-15 Oxadiazole, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
EE9900147A true EE9900147A (et) 1999-12-15

Family

ID=7809114

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP199900147A EE9900147A (et) 1996-10-18 1997-10-15 Oksadiasoolid, nende saamismeetodid ja kasutamine ravimitena

Country Status (32)

Country Link
US (1) US6277872B1 (et)
EP (1) EP0934288B1 (et)
JP (1) JP3333523B2 (et)
KR (1) KR20000049253A (et)
CN (1) CN1086698C (et)
AR (1) AR008496A1 (et)
AT (1) ATE315034T1 (et)
AU (1) AU737552B2 (et)
BG (1) BG103251A (et)
BR (1) BR9714354A (et)
CA (1) CA2268954C (et)
CO (1) CO4920253A1 (et)
CZ (1) CZ138099A3 (et)
DE (2) DE19643037A1 (et)
EE (1) EE9900147A (et)
ES (1) ES2256880T3 (et)
HK (1) HK1020956A1 (et)
HR (1) HRP970553A2 (et)
HU (1) HUP0001652A3 (et)
ID (1) ID18613A (et)
IL (1) IL129315A0 (et)
NO (1) NO312512B1 (et)
NZ (1) NZ335598A (et)
PE (1) PE11199A1 (et)
PL (1) PL332432A1 (et)
RU (1) RU2182905C2 (et)
SK (1) SK49999A3 (et)
TR (1) TR199900848T2 (et)
TW (1) TW413678B (et)
WO (1) WO1998017652A1 (et)
YU (1) YU40997A (et)
ZA (1) ZA979220B (et)

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US6660753B2 (en) 1999-08-19 2003-12-09 Nps Pharmaceuticals, Inc. Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
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US6579880B2 (en) * 2000-06-06 2003-06-17 Ortho-Mcneil Pharmaceutical, Inc. Isoxazoles and oxadiazoles as anti-inflammatory inhibitors of IL-8
WO2001096308A1 (fr) 2000-06-12 2001-12-20 Eisai Co., Ltd. Composes 1,2-dihydropyridine, leur procede de preparation et leur utilisation
CN100473647C (zh) * 2000-09-18 2009-04-01 卫材R&D管理有限公司 哒嗪酮和三嗪酮化合物及其作为药物制剂的用途
RU2319701C2 (ru) * 2001-02-21 2008-03-20 Астразенека Аб ГЕТЕРОПОЛИЦИКЛИЧЕСКОЕ СОЕДИНЕНИЕ, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, ОБЛАДАЮЩАЯ АНТАГОНИСТИЧЕСКОЙ АКТИВНОСТЬЮ В ОТНОШЕНИИ МЕТАБОТРОПНЫХ ГЛЮТАМАТНЫХ РЕЦЕПТОРОВ mGluR ГРУППЫ I
AU2002341921B2 (en) * 2001-10-04 2007-05-31 Merck Sharp & Dohme Corp. Heteroaryl substituted tetrazole modulators of metabotropic glutamate receptor-5
MY151199A (en) 2001-11-02 2014-04-30 Rigel Pharmaceuticals Inc Substituted diphenyl heterocycles useful for treating hcv infection
GB0129260D0 (en) 2001-12-06 2002-01-23 Eisai London Res Lab Ltd Pharmaceutical compositions and their uses
JP2006501312A (ja) 2002-08-23 2006-01-12 ライジェル ファーマシューティカルズ， インコーポレイテッド Ｈｃｖ感染を治療または予防するのに有用なピリジル置換複素環
GB0303503D0 (en) * 2003-02-14 2003-03-19 Novartis Ag Organic compounds
WO2004099164A1 (en) * 2003-05-02 2004-11-18 Rigel Pharmaceuticals, Inc. Substituted diphenyl isoxazoles, pyrazoles and oxadiazoles useful for treating hcv infection
EP1620412A2 (en) 2003-05-02 2006-02-01 Rigel Pharmaceuticals, Inc. Heterocyclic compounds and hydro isomers thereof
US7220745B2 (en) 2003-05-15 2007-05-22 Rigel Pharmaceuticals Heterocyclic compounds useful to treat HCV
WO2005049065A2 (en) 2003-11-19 2005-06-02 Rigel Pharmaceuticals, Inc. Synergistic combinations of dihaloacetamide with interferon or ribavirin for treatment hcv infections
NZ547965A (en) * 2003-12-24 2009-12-24 Prosidion Ltd 1,2,4-Oxadiazole derivatives as GPCR receptor agonists
US7514434B2 (en) 2004-02-23 2009-04-07 Rigel Pharmaceuticals, Inc. Heterocyclic compounds having an oxadiazole moiety and hydro isomers thereof
MY148809A (en) 2004-07-06 2013-05-31 Eisai R&D Man Co Ltd Crystals of 1,2-dihydropyridine compound and their production process
RU2007141401A (ru) * 2005-04-08 2009-05-20 ЭЙСАЙ Ар энд Ди МЕНЕДЖМЕНТ КО., ЛТД. (JP) Терапевтический агент для лечения дискинезии
CA2606106A1 (en) 2005-05-02 2007-03-08 Rigel Pharmaceuticals, Inc. Heterocyclic anti-viral compounds comprising metabolizable moieties and their uses
GB0510142D0 (en) * 2005-05-18 2005-06-22 Addex Pharmaceuticals Sa Novel compounds A1
HUP0500920A2 (en) * 2005-10-05 2007-07-30 Richter Gedeon Nyrt Oxadiazole derivatives, process for their preparation and their use
AU2007334436A1 (en) * 2006-12-15 2008-06-26 Abbott Laboratories Novel oxadiazole compounds
US20110207704A1 (en) * 2006-12-15 2011-08-25 Abbott Laboratories Novel Oxadiazole Compounds
JO2701B1 (en) 2006-12-21 2013-03-03 جلاكسو جروب ليميتد Vehicles
JP5727223B2 (ja) * 2007-10-04 2015-06-03 メルク セローノ ソシエテ アノニム オキサジアゾール・ジアリール化合物
WO2009082398A1 (en) * 2007-12-21 2009-07-02 University Of Notre Dame Du Lac Antibacterial compounds and methods of using same
PL2684873T3 (pl) 2008-06-09 2019-07-31 Ludwig-Maximilians-Universität München Leki do hamowania agregacji białek związanych z chorobami związanymi z agregacją białka i/lub chorobami neurodegeneracyjnymi
WO2011047129A1 (en) 2009-10-15 2011-04-21 Southern Research Institute Treatment of neurodegenerative diseases, causation of memory enhancement, and assay for screening compounds for such
NZ705167A (en) * 2012-08-24 2017-12-22 Treventis Corp Benzofurazan anti-amyloid compounds and methods
HUE044999T2 (hu) 2014-02-27 2019-12-30 Treventis Corp Benzofurazán tartalmú anti-amiloid vegyületek
JP6493394B2 (ja) 2014-04-24 2019-04-03 住友化学株式会社 ジアリール−アゾール化合物
KR20170113529A (ko) * 2014-09-25 2017-10-12 유니버시티 오브 노트르 담 듀락 비-베타 락탐 항생제
CN107286174B (zh) * 2016-04-11 2020-08-18 上海勋和医药科技有限公司 取代2,4-(1h,3h)嘧啶二酮作为parp抑制剂及其应用
US11168062B2 (en) 2016-09-12 2021-11-09 University Of Notre Dame Du Lac Compounds for the treatment of Clostridium difficile infection
AU2018265584B2 (en) 2017-05-12 2023-09-28 Ludwig-Maximilians-Universität München Phenyl-heterocycle-phenyl derivatives for use in the treatment or prevention of melanoma
US10676467B2 (en) 2017-06-30 2020-06-09 Washington University Compositions for binding sphingosine-1-phosphate receptor 1 (S1P1), imaging of S1P1, and methods of use thereof
CA3122705A1 (en) 2018-12-14 2020-06-18 Eisai R&D Management Co., Ltd. Aqueous based pharmaceutical formulations of 1,2-dihydropyridine compounds
WO2023042888A1 (ja) 2021-09-15 2023-03-23 国立大学法人 琉球大学 認知機能低下、または過体重もしくは肥満症を処置することに用いるための医薬組成物
WO2023042887A1 (ja) 2021-09-15 2023-03-23 国立大学法人 琉球大学 認知機能低下、または過体重もしくは肥満症を処置することに用いるための医薬組成物
EP4173485A1 (en) 2021-10-27 2023-05-03 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Protein aggregation inhibiting compounds for plant disease control

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DE2801509A1 (de) * 1978-01-12 1979-07-19 Schering Ag 1,2,4-oxadiazolderivate, verfahren zur herstellung dieser verbindungen sowie diese enthaltende selektive herbizide mittel
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US4871753A (en) * 1986-12-12 1989-10-03 Ciba-Geigy Corporation 3-Phenyl-5-trifluoromethyl-1,2,4-oxadiazole compounds which are useful pesticides
DE3905242A1 (de) * 1989-02-21 1990-08-23 Basf Ag Verfahren zur herstellung von phenyloxdiazolylanilinen
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Also Published As

Publication number Publication date
NO991815D0 (no) 1999-04-16
CZ138099A3 (cs) 1999-11-17
PE11199A1 (es) 1999-03-03
EP0934288A1 (de) 1999-08-11
AU4867697A (en) 1998-05-15
AU737552B2 (en) 2001-08-23
IL129315A0 (en) 2000-02-17
AR008496A1 (es) 2000-01-19
CA2268954A1 (en) 1998-04-30
WO1998017652A1 (de) 1998-04-30
ATE315034T1 (de) 2006-02-15
JP2000505089A (ja) 2000-04-25
PL332432A1 (en) 1999-09-13
KR20000049253A (ko) 2000-07-25
EP0934288B1 (de) 2006-01-04
BG103251A (en) 2000-02-29
US6277872B1 (en) 2001-08-21
DE59712543D1 (de) 2006-03-30
CN1233245A (zh) 1999-10-27
NZ335598A (en) 2001-06-29
YU40997A (sh) 2000-10-30
TR199900848T2 (xx) 1999-06-21
HUP0001652A3 (en) 2002-12-28
ID18613A (id) 1998-04-23
CA2268954C (en) 2006-06-13
NO991815L (no) 1999-04-16
SK49999A3 (en) 1999-11-08
ZA979220B (en) 1998-04-20
CN1086698C (zh) 2002-06-26
ES2256880T3 (es) 2006-07-16
HUP0001652A2 (hu) 2001-01-29
JP3333523B2 (ja) 2002-10-15
HK1020956A1 (en) 2000-05-26
TW413678B (en) 2000-12-01
BR9714354A (pt) 2000-04-11
NO312512B1 (no) 2002-05-21
DE19643037A1 (de) 1998-04-23
CO4920253A1 (es) 2000-05-29
HRP970553A2 (en) 1998-08-31
RU2182905C2 (ru) 2002-05-27

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