ID18613A - Oksadiazol baru, proses pembuatannya serta penggunaannya sebagai komposisi farmasi - Google Patents

Oksadiazol baru, proses pembuatannya serta penggunaannya sebagai komposisi farmasi

Info

Publication number
ID18613A
ID18613A IDP973449A ID973449A ID18613A ID 18613 A ID18613 A ID 18613A ID P973449 A IDP973449 A ID P973449A ID 973449 A ID973449 A ID 973449A ID 18613 A ID18613 A ID 18613A
Authority
ID
Indonesia
Prior art keywords
oxadiazol
making
new
pharmaceutical composition
pharmaceutical
Prior art date
Application number
IDP973449A
Other languages
English (en)
Inventor
Michael Brenner
Roland Maier
Marion Wienrich
Thomas Weiser
Rainer Palluk
Wolf-Dietrich Bechtel
Angelo Sagrada
Helmut Ensinger
Uwe Pschorn
Raffaele Cesana
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of ID18613A publication Critical patent/ID18613A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IDP973449A 1996-10-18 1997-10-16 Oksadiazol baru, proses pembuatannya serta penggunaannya sebagai komposisi farmasi ID18613A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19643037A DE19643037A1 (de) 1996-10-18 1996-10-18 Neue Oxadiazole, Verfahren zu ihrer Herstellung sowie deren Verwendung als Arzneimittel

Publications (1)

Publication Number Publication Date
ID18613A true ID18613A (id) 1998-04-23

Family

ID=7809114

Family Applications (1)

Application Number Title Priority Date Filing Date
IDP973449A ID18613A (id) 1996-10-18 1997-10-16 Oksadiazol baru, proses pembuatannya serta penggunaannya sebagai komposisi farmasi

Country Status (32)

Country Link
US (1) US6277872B1 (id)
EP (1) EP0934288B1 (id)
JP (1) JP3333523B2 (id)
KR (1) KR20000049253A (id)
CN (1) CN1086698C (id)
AR (1) AR008496A1 (id)
AT (1) ATE315034T1 (id)
AU (1) AU737552B2 (id)
BG (1) BG103251A (id)
BR (1) BR9714354A (id)
CA (1) CA2268954C (id)
CO (1) CO4920253A1 (id)
CZ (1) CZ138099A3 (id)
DE (2) DE19643037A1 (id)
EE (1) EE9900147A (id)
ES (1) ES2256880T3 (id)
HK (1) HK1020956A1 (id)
HR (1) HRP970553A2 (id)
HU (1) HUP0001652A3 (id)
ID (1) ID18613A (id)
IL (1) IL129315A0 (id)
NO (1) NO312512B1 (id)
NZ (1) NZ335598A (id)
PE (1) PE11199A1 (id)
PL (1) PL332432A1 (id)
RU (1) RU2182905C2 (id)
SK (1) SK49999A3 (id)
TR (1) TR199900848T2 (id)
TW (1) TW413678B (id)
WO (1) WO1998017652A1 (id)
YU (1) YU40997A (id)
ZA (1) ZA979220B (id)

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IT1300055B1 (it) 1998-04-17 2000-04-05 Boehringer Ingelheim Italia Eterocicli con anello a 5 termini difenil-sostituiti loro procedimento di preparazione e loro impiego come farmici
IT1300056B1 (it) * 1998-04-17 2000-04-05 Boehringer Ingelheim Italia Eterocicli con anello a 6 termini difenil-sostituiti loro procedimento di preparazione e loro impiego come farmaci
US6107313A (en) * 1998-10-02 2000-08-22 Combichem, Inc. Dopamine receptor antagonists
US6825192B1 (en) 1999-02-15 2004-11-30 Eisai Co., Ltd. Heterodiazinone derivatives
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EP1582519A3 (en) * 1999-08-19 2005-12-21 Nps Pharmaceuticals, Inc. Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
US6660753B2 (en) 1999-08-19 2003-12-09 Nps Pharmaceuticals, Inc. Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
CZ2002599A3 (cs) * 1999-08-19 2002-06-12 Nps Pharmaceuticals Inc. Heteropolycyklické sloučeniny a jejich pouľití jako antagonistů metabotropního receptoru glutamátu
US6579880B2 (en) * 2000-06-06 2003-06-17 Ortho-Mcneil Pharmaceutical, Inc. Isoxazoles and oxadiazoles as anti-inflammatory inhibitors of IL-8
PT1300396E (pt) 2000-06-12 2009-04-20 Eisai R&D Man Co Ltd Compostos de 1,2-di-hidropiridina, processos para a sua preparação e sua utilização
CN100473647C (zh) * 2000-09-18 2009-04-01 卫材R&D管理有限公司 哒嗪酮和三嗪酮化合物及其作为药物制剂的用途
ATE375340T1 (de) * 2001-02-21 2007-10-15 Nps Pharma Inc Heteropolycyclische verbindungen und deren verwendung als metabotrope glutamatrezeptorantagonisten
WO2003029210A2 (en) * 2001-10-04 2003-04-10 Merck & Co. Inc. Heteroaryl substituted tetrazole modulators of metabotropic glutamate receptor-5
MY151199A (en) 2001-11-02 2014-04-30 Rigel Pharmaceuticals Inc Substituted diphenyl heterocycles useful for treating hcv infection
GB0129260D0 (en) 2001-12-06 2002-01-23 Eisai London Res Lab Ltd Pharmaceutical compositions and their uses
CA2494164A1 (en) 2002-08-23 2004-03-04 Rigel Pharmaceuticals, Inc. Pyridyl substituted heterocycles useful for treating or preventing hcv infection
GB0303503D0 (en) * 2003-02-14 2003-03-19 Novartis Ag Organic compounds
WO2004099164A1 (en) * 2003-05-02 2004-11-18 Rigel Pharmaceuticals, Inc. Substituted diphenyl isoxazoles, pyrazoles and oxadiazoles useful for treating hcv infection
US7326790B2 (en) 2003-05-02 2008-02-05 Rigel Pharmaceuticals, Inc. Diphenylisoxazole compounds and hydro isomers thereof
US7220745B2 (en) 2003-05-15 2007-05-22 Rigel Pharmaceuticals Heterocyclic compounds useful to treat HCV
WO2005049065A2 (en) 2003-11-19 2005-06-02 Rigel Pharmaceuticals, Inc. Synergistic combinations of dihaloacetamide with interferon or ribavirin for treatment hcv infections
NZ547965A (en) * 2003-12-24 2009-12-24 Prosidion Ltd 1,2,4-Oxadiazole derivatives as GPCR receptor agonists
US7514434B2 (en) 2004-02-23 2009-04-07 Rigel Pharmaceuticals, Inc. Heterocyclic compounds having an oxadiazole moiety and hydro isomers thereof
MY148809A (en) 2004-07-06 2013-05-31 Eisai R&D Man Co Ltd Crystals of 1,2-dihydropyridine compound and their production process
AU2006234627C1 (en) * 2005-04-08 2009-11-26 Eisai R & D Management Co., Ltd. Therapeutic agent for dyskinesia
CN101203498A (zh) 2005-05-02 2008-06-18 里格尔药品股份有限公司 包括可代谢部分的杂环抗病毒化合物及其用途
GB0510142D0 (en) * 2005-05-18 2005-06-22 Addex Pharmaceuticals Sa Novel compounds A1
HUP0500920A2 (en) * 2005-10-05 2007-07-30 Richter Gedeon Nyrt Oxadiazole derivatives, process for their preparation and their use
US20110207704A1 (en) * 2006-12-15 2011-08-25 Abbott Laboratories Novel Oxadiazole Compounds
MX2009006304A (es) * 2006-12-15 2009-06-23 Abbott Lab Nuevos compuestos de oxadiazol.
JO2701B1 (en) 2006-12-21 2013-03-03 جلاكسو جروب ليميتد Vehicles
CA2696829C (en) * 2007-10-04 2017-07-04 Merck Serono S.A. Oxadiazole diaryl compounds
US9045442B2 (en) * 2007-12-21 2015-06-02 University Of Notre Dame Du Lac Antibacterial compounds and methods of using same
HUE053352T2 (hu) 2008-06-09 2021-06-28 Univ Muenchen Ludwig Maximilians Új hatóanyagok fehérje-aggregációval kapcsolatos betegségeknél és/vagy neurodegeneratív betegségeknél szerepet játszó fehérjék aggregációjának gátlására
US9095596B2 (en) 2009-10-15 2015-08-04 Southern Research Institute Treatment of neurodegenerative diseases, causation of memory enhancement, and assay for screening compounds for such
RU2641293C2 (ru) * 2012-08-24 2018-01-17 Тревентис Корпорейшн Бензофуразановые антимилоидные соединения и способы
DK3110812T3 (da) 2014-02-27 2019-07-08 Treventis Corp Anti-amyloidforbindelser indeholdende benzofurazan
US9884858B2 (en) 2014-04-24 2018-02-06 Sumitomo Chemical Company, Limited Diaryl-azole compound
JP2017533187A (ja) * 2014-09-25 2017-11-09 ユニヴァーシティー オブ ノートル ダム デュ ラック 非β−ラクタム系抗生物質
CN107286174B (zh) * 2016-04-11 2020-08-18 上海勋和医药科技有限公司 取代2,4-(1h,3h)嘧啶二酮作为parp抑制剂及其应用
US11168062B2 (en) 2016-09-12 2021-11-09 University Of Notre Dame Du Lac Compounds for the treatment of Clostridium difficile infection
CA3062749A1 (en) 2017-05-12 2018-11-15 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V. Compounds for use in the treatment or prevention of melanoma
US10676467B2 (en) 2017-06-30 2020-06-09 Washington University Compositions for binding sphingosine-1-phosphate receptor 1 (S1P1), imaging of S1P1, and methods of use thereof
AU2019395288A1 (en) 2018-12-14 2021-09-23 Eisai R&D Management Co., Ltd. Aqueous based pharmaceutical formulations of 1,2-dihydropyridine compounds
JPWO2023042887A1 (id) 2021-09-15 2023-03-23
JPWO2023042888A1 (id) 2021-09-15 2023-03-23
EP4173485A1 (en) 2021-10-27 2023-05-03 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Protein aggregation inhibiting compounds for plant disease control

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US4003909A (en) * 1974-07-22 1977-01-18 E. R. Squibb & Sons, Inc. [(1,2,4-Oxadiazol-3-yl)phenyl]carbamic or thiocarbamic acid esters
JPS52272A (en) * 1975-10-17 1977-01-05 Takeda Chem Ind Ltd Process for preparing 1,2,4-oxadiazole derivatives
DE2801509A1 (de) * 1978-01-12 1979-07-19 Schering Ag 1,2,4-oxadiazolderivate, verfahren zur herstellung dieser verbindungen sowie diese enthaltende selektive herbizide mittel
JPS58150576A (ja) * 1982-03-03 1983-09-07 Sumitomo Chem Co Ltd 新規な１，２，４−オキサジアゾ−ル誘導体
US4871753A (en) * 1986-12-12 1989-10-03 Ciba-Geigy Corporation 3-Phenyl-5-trifluoromethyl-1,2,4-oxadiazole compounds which are useful pesticides
DE3905242A1 (de) * 1989-02-21 1990-08-23 Basf Ag Verfahren zur herstellung von phenyloxdiazolylanilinen
JPH02250873A (ja) * 1989-03-24 1990-10-08 Mitsubishi Petrochem Co Ltd １，２，４―オキサジアゾール誘導体及びそれを有効成分とする除草剤
NZ234760A (en) * 1989-08-18 1991-09-25 Sterling Drug Inc Antiviral oxazole compounds and compositions
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JPH04295470A (ja) * 1991-03-22 1992-10-20 Wakamoto Pharmaceut Co Ltd モノアミンオキシダーゼ−ｂ酵素阻害活性を有する１，２，４−オキサジアゾール誘導体及びその製造法
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DE4401108A1 (de) * 1994-01-17 1995-07-20 Bayer Ag 1,2,4-Oxadiazol-Derivate
DE4401107A1 (de) * 1994-01-17 1995-07-20 Bayer Ag 3-Aryl-alkenyl-1,2,4-oxadiazol-Derivate
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Also Published As

Publication number Publication date
TR199900848T2 (xx) 1999-06-21
HUP0001652A2 (hu) 2001-01-29
ATE315034T1 (de) 2006-02-15
IL129315A0 (en) 2000-02-17
PE11199A1 (es) 1999-03-03
CN1086698C (zh) 2002-06-26
DE19643037A1 (de) 1998-04-23
ES2256880T3 (es) 2006-07-16
CN1233245A (zh) 1999-10-27
EE9900147A (et) 1999-12-15
CA2268954A1 (en) 1998-04-30
NO312512B1 (no) 2002-05-21
YU40997A (sh) 2000-10-30
WO1998017652A1 (de) 1998-04-30
RU2182905C2 (ru) 2002-05-27
HRP970553A2 (en) 1998-08-31
DE59712543D1 (de) 2006-03-30
BR9714354A (pt) 2000-04-11
CO4920253A1 (es) 2000-05-29
CA2268954C (en) 2006-06-13
CZ138099A3 (cs) 1999-11-17
HUP0001652A3 (en) 2002-12-28
JP2000505089A (ja) 2000-04-25
EP0934288A1 (de) 1999-08-11
SK49999A3 (en) 1999-11-08
US6277872B1 (en) 2001-08-21
HK1020956A1 (en) 2000-05-26
NO991815D0 (no) 1999-04-16
AU737552B2 (en) 2001-08-23
NZ335598A (en) 2001-06-29
PL332432A1 (en) 1999-09-13
NO991815L (no) 1999-04-16
ZA979220B (en) 1998-04-20
AR008496A1 (es) 2000-01-19
BG103251A (en) 2000-02-29
AU4867697A (en) 1998-05-15
TW413678B (en) 2000-12-01
KR20000049253A (ko) 2000-07-25
EP0934288B1 (de) 2006-01-04
JP3333523B2 (ja) 2002-10-15

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