BG103251A - Oxydiazols, methods for their preparation and application as medicamentous forms - Google Patents

Oxydiazols, methods for their preparation and application as medicamentous forms

Info

Publication number
BG103251A
BG103251A BG103251A BG10325199A BG103251A BG 103251 A BG103251 A BG 103251A BG 103251 A BG103251 A BG 103251A BG 10325199 A BG10325199 A BG 10325199A BG 103251 A BG103251 A BG 103251A
Authority
BG
Bulgaria
Prior art keywords
preparation
methods
application
oxydiazols
medicamentous forms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
BG103251A
Other languages
Bulgarian (bg)
English (en)
Inventor
Michael Brenner
Roland Maier
Marion Wienrich
Thomas Weiser
Rainer Palluk
Wolf-Dietrich Bechtel
Angelo Sagrada
Helmut Ensinger
Uwe Pschorn
Raffaele Cesana
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH Co KG
Original Assignee
Boehringer Ingelheim Pharma GmbH Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma GmbH Co KG filed Critical Boehringer Ingelheim Pharma GmbH Co KG
Publication of BG103251A publication Critical patent/BG103251A/xx
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BG103251A 1996-10-18 1999-03-15 Oxydiazols, methods for their preparation and application as medicamentous forms Pending BG103251A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19643037A DE19643037A1 (de) 1996-10-18 1996-10-18 Neue Oxadiazole, Verfahren zu ihrer Herstellung sowie deren Verwendung als Arzneimittel
PCT/EP1997/005693 WO1998017652A1 (de) 1996-10-18 1997-10-15 Oxadiazole, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
BG103251A true BG103251A (en) 2000-02-29

Family

ID=7809114

Family Applications (1)

Application Number Title Priority Date Filing Date
BG103251A Pending BG103251A (en) 1996-10-18 1999-03-15 Oxydiazols, methods for their preparation and application as medicamentous forms

Country Status (32)

Country Link
US (1) US6277872B1 (xx)
EP (1) EP0934288B1 (xx)
JP (1) JP3333523B2 (xx)
KR (1) KR20000049253A (xx)
CN (1) CN1086698C (xx)
AR (1) AR008496A1 (xx)
AT (1) ATE315034T1 (xx)
AU (1) AU737552B2 (xx)
BG (1) BG103251A (xx)
BR (1) BR9714354A (xx)
CA (1) CA2268954C (xx)
CO (1) CO4920253A1 (xx)
CZ (1) CZ138099A3 (xx)
DE (2) DE19643037A1 (xx)
EE (1) EE9900147A (xx)
ES (1) ES2256880T3 (xx)
HK (1) HK1020956A1 (xx)
HR (1) HRP970553A2 (xx)
HU (1) HUP0001652A3 (xx)
ID (1) ID18613A (xx)
IL (1) IL129315A0 (xx)
NO (1) NO312512B1 (xx)
NZ (1) NZ335598A (xx)
PE (1) PE11199A1 (xx)
PL (1) PL332432A1 (xx)
RU (1) RU2182905C2 (xx)
SK (1) SK49999A3 (xx)
TR (1) TR199900848T2 (xx)
TW (1) TW413678B (xx)
WO (1) WO1998017652A1 (xx)
YU (1) YU40997A (xx)
ZA (1) ZA979220B (xx)

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US6825192B1 (en) 1999-02-15 2004-11-30 Eisai Co., Ltd. Heterodiazinone derivatives
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UA75871C2 (en) * 1999-08-19 2006-06-15 Nps Pharma Inc 1,2,4-oxadiazole derivatives and use thereof as antagonists at metabotropic glutamate receptors
EP1582519A3 (en) * 1999-08-19 2005-12-21 Nps Pharmaceuticals, Inc. Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
US6579880B2 (en) * 2000-06-06 2003-06-17 Ortho-Mcneil Pharmaceutical, Inc. Isoxazoles and oxadiazoles as anti-inflammatory inhibitors of IL-8
NZ522773A (en) 2000-06-12 2005-06-24 Eisai Co Ltd 1,2-dihydropyridine compounds, manufacturing method thereof and use thereof
KR100770327B1 (ko) * 2000-09-18 2007-10-25 에자이 알앤드디 매니지먼트 가부시키가이샤 피리다지논 및 트리아지논 화합물류 및 그들의 의약 용도
SI1379525T1 (sl) * 2001-02-21 2007-12-31 Astrazeneca Ab Heteropoliciklične spojine in njihova uporaba kot antagonisti metabotropnih glutamatnih receptorjev
ATE396186T1 (de) * 2001-10-04 2008-06-15 Merck & Co Inc Heteroarylsubstituierte tetrazolmodulatoren des metabotropischen glutamatrezeptors-5
MY151199A (en) 2001-11-02 2014-04-30 Rigel Pharmaceuticals Inc Substituted diphenyl heterocycles useful for treating hcv infection
GB0129260D0 (en) 2001-12-06 2002-01-23 Eisai London Res Lab Ltd Pharmaceutical compositions and their uses
JP2006501312A (ja) 2002-08-23 2006-01-12 ライジェル ファーマシューティカルズ， インコーポレイテッド Ｈｃｖ感染を治療または予防するのに有用なピリジル置換複素環
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US7115642B2 (en) 2003-05-02 2006-10-03 Rigel Pharmaceuticals, Inc. Substituted diphenyl isoxazoles, pyrazoles and oxadiazoles useful for treating HCV infection
EP1620412A2 (en) 2003-05-02 2006-02-01 Rigel Pharmaceuticals, Inc. Heterocyclic compounds and hydro isomers thereof
US7220745B2 (en) 2003-05-15 2007-05-22 Rigel Pharmaceuticals Heterocyclic compounds useful to treat HCV
WO2005049065A2 (en) 2003-11-19 2005-06-02 Rigel Pharmaceuticals, Inc. Synergistic combinations of dihaloacetamide with interferon or ribavirin for treatment hcv infections
CN1898235A (zh) 2003-12-24 2007-01-17 普罗西迪恩有限公司 作为gpcr受体激动剂的杂环衍生物
US7514434B2 (en) 2004-02-23 2009-04-07 Rigel Pharmaceuticals, Inc. Heterocyclic compounds having an oxadiazole moiety and hydro isomers thereof
MY148809A (en) 2004-07-06 2013-05-31 Eisai R&D Man Co Ltd Crystals of 1,2-dihydropyridine compound and their production process
CA2603959A1 (en) * 2005-04-08 2006-10-19 Eisai R & D Management Co., Ltd. Therapeutic agent for dyskinesia
CN101203498A (zh) 2005-05-02 2008-06-18 里格尔药品股份有限公司 包括可代谢部分的杂环抗病毒化合物及其用途
GB0510142D0 (en) * 2005-05-18 2005-06-22 Addex Pharmaceuticals Sa Novel compounds A1
HUP0500920A2 (en) * 2005-10-05 2007-07-30 Richter Gedeon Nyrt Oxadiazole derivatives, process for their preparation and their use
US20110207704A1 (en) * 2006-12-15 2011-08-25 Abbott Laboratories Novel Oxadiazole Compounds
BRPI0720043A2 (pt) * 2006-12-15 2014-01-07 Abbott Lab Composto oxadiazol
JO2701B1 (en) 2006-12-21 2013-03-03 جلاكسو جروب ليميتد Vehicles
AU2008306886B2 (en) * 2007-10-04 2014-01-16 Merck Serono S.A. Oxadiazole diaryl compounds
WO2009082398A1 (en) * 2007-12-21 2009-07-02 University Of Notre Dame Du Lac Antibacterial compounds and methods of using same
EP2307381B1 (en) 2008-06-09 2021-01-13 Ludwig-Maximilians-Universität München New drugs for inhibiting aggregation of proteins involved in diseases linked to protein aggregation and/or neurodegenerative diseases
WO2011047129A1 (en) * 2009-10-15 2011-04-21 Southern Research Institute Treatment of neurodegenerative diseases, causation of memory enhancement, and assay for screening compounds for such
US9328078B2 (en) * 2012-08-24 2016-05-03 Treventis Corporation Benzofurazan anti-amyloid compounds and methods
WO2015131021A2 (en) 2014-02-27 2015-09-03 Treventis Corporation Anti-amyloid compounds containing benzofurazan
WO2015163478A1 (ja) 2014-04-24 2015-10-29 住友化学株式会社 ジアリール－アゾール化合物
CA2962431A1 (en) * 2014-09-25 2016-03-31 University Of Notre Dame Du Lac Non-beta lactam antibiotics
CN107286174B (zh) * 2016-04-11 2020-08-18 上海勋和医药科技有限公司 取代2,4-(1h,3h)嘧啶二酮作为parp抑制剂及其应用
WO2018049404A1 (en) 2016-09-12 2018-03-15 University Of Notre Dame Du Lac Compounds for the treatment of clostridium difficile infection
JP7283699B2 (ja) 2017-05-12 2023-05-30 マックス－プランク－ゲゼルシャフト・ツア・フェルデルング・デア・ヴィッセンシャフテン・エー・ファオ 黒色腫の治療または予防において使用するためのフェニル－ヘテロ環－フェニル誘導体
US10676467B2 (en) 2017-06-30 2020-06-09 Washington University Compositions for binding sphingosine-1-phosphate receptor 1 (S1P1), imaging of S1P1, and methods of use thereof
CN113226286B (zh) 2018-12-14 2024-08-20 卫材R&D管理有限公司 1,2-二氢吡啶化合物的水基药物制剂
EP4403184A1 (en) 2021-09-15 2024-07-24 University of The Ryukyus Pharmaceutical composition for use in treating cognitive decline, excess weight, or obesity
WO2023042888A1 (ja) 2021-09-15 2023-03-23 国立大学法人 琉球大学 認知機能低下、または過体重もしくは肥満症を処置することに用いるための医薬組成物
EP4173485A1 (en) 2021-10-27 2023-05-03 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Protein aggregation inhibiting compounds for plant disease control

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Also Published As

Publication number Publication date
TW413678B (en) 2000-12-01
CN1233245A (zh) 1999-10-27
JP3333523B2 (ja) 2002-10-15
TR199900848T2 (xx) 1999-06-21
AU4867697A (en) 1998-05-15
CA2268954A1 (en) 1998-04-30
HK1020956A1 (en) 2000-05-26
WO1998017652A1 (de) 1998-04-30
ES2256880T3 (es) 2006-07-16
EE9900147A (et) 1999-12-15
CO4920253A1 (es) 2000-05-29
PE11199A1 (es) 1999-03-03
NO991815L (no) 1999-04-16
KR20000049253A (ko) 2000-07-25
RU2182905C2 (ru) 2002-05-27
NO312512B1 (no) 2002-05-21
IL129315A0 (en) 2000-02-17
HUP0001652A2 (hu) 2001-01-29
EP0934288B1 (de) 2006-01-04
AU737552B2 (en) 2001-08-23
US6277872B1 (en) 2001-08-21
HUP0001652A3 (en) 2002-12-28
PL332432A1 (en) 1999-09-13
AR008496A1 (es) 2000-01-19
DE59712543D1 (de) 2006-03-30
ID18613A (id) 1998-04-23
BR9714354A (pt) 2000-04-11
SK49999A3 (en) 1999-11-08
CA2268954C (en) 2006-06-13
EP0934288A1 (de) 1999-08-11
CN1086698C (zh) 2002-06-26
JP2000505089A (ja) 2000-04-25
NO991815D0 (no) 1999-04-16
DE19643037A1 (de) 1998-04-23
YU40997A (sh) 2000-10-30
HRP970553A2 (en) 1998-08-31
NZ335598A (en) 2001-06-29
CZ138099A3 (cs) 1999-11-17
ZA979220B (en) 1998-04-20
ATE315034T1 (de) 2006-02-15

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