ECSP066670A - Prodroga florfenicol con mejor solubilidad en agua - Google Patents

Prodroga florfenicol con mejor solubilidad en agua

Info

Publication number
ECSP066670A
ECSP066670A EC2006006670A ECSP066670A ECSP066670A EC SP066670 A ECSP066670 A EC SP066670A EC 2006006670 A EC2006006670 A EC 2006006670A EC SP066670 A ECSP066670 A EC SP066670A EC SP066670 A ECSP066670 A EC SP066670A
Authority
EC
Ecuador
Prior art keywords
florfenicol
water
products
better solubility
solubility
Prior art date
Application number
EC2006006670A
Other languages
English (en)
Spanish (es)
Inventor
Scott J Hecker
Sunil V Pansare
Original Assignee
Schering Plough Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34738768&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP066670(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Plough Ltd filed Critical Schering Plough Ltd
Publication of ECSP066670A publication Critical patent/ECSP066670A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/094—Esters of phosphoric acids with arylalkanols

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EC2006006670A 2003-12-23 2006-06-22 Prodroga florfenicol con mejor solubilidad en agua ECSP066670A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53222703P 2003-12-23 2003-12-23

Publications (1)

Publication Number Publication Date
ECSP066670A true ECSP066670A (es) 2006-10-25

Family

ID=34738768

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2006006670A ECSP066670A (es) 2003-12-23 2006-06-22 Prodroga florfenicol con mejor solubilidad en agua

Country Status (18)

Country Link
US (2) US7153842B2 (https=)
EP (1) EP1696934B1 (https=)
JP (2) JP4719160B2 (https=)
KR (1) KR20060111605A (https=)
CN (1) CN100579532C (https=)
AR (1) AR046970A1 (https=)
BR (1) BRPI0418133A2 (https=)
CA (1) CA2550660C (https=)
EC (1) ECSP066670A (https=)
IL (2) IL176342A (https=)
MX (1) MXPA06007215A (https=)
NO (1) NO20063244L (https=)
NZ (1) NZ547592A (https=)
PE (1) PE20050822A1 (https=)
RU (1) RU2006126519A (https=)
TW (1) TWI262181B (https=)
WO (1) WO2005063257A1 (https=)
ZA (1) ZA200605165B (https=)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200505425A (en) 2003-05-29 2005-02-16 Schering Plough Ltd Compositions and method for treating infection in cattle and swine
US7439268B2 (en) 2003-07-18 2008-10-21 Idexx Laboratories Compositions containing prodrugs of florfenicol and methods of use
AR046970A1 (es) * 2003-12-23 2006-01-04 Schering Plough Ltd Esteres de fosfato de florfenicol
US7361689B2 (en) * 2003-12-31 2008-04-22 Schering-Plough Animal Health Corporation Antibacterial 1-(4-mono- and di-halomethylsulphonylphenyl)-2-acylamino-3-fluoroproponals and preparation thereof
AU2005286723A1 (en) 2004-09-23 2006-03-30 Schering-Plough Pty. Limited Control of parasites in animals by the use of novel trifluoromethanesulfonanilide oxime ether derivatives
DE602005017419D1 (de) 2004-11-19 2009-12-10 Schering Plough Ltd Kontrolle von parasiten bei tieren mittels verwendung von parasitiziden 2-phenyl-3-(1h-pyrrol-2-yl) acrylonitril-derivaten
CA2609574A1 (en) * 2005-06-09 2006-12-21 Schering-Plough Ltd. Control of parasites in animals by n-[(phenyloxy)phenyl]-1,1,1-trifluoromethanesulfonamide and n-[(phenylsulfanyl)phenyl]-1,1,1-trifluoromethanesulfonamide derivatives
US8119667B2 (en) * 2005-12-29 2012-02-21 Schering-Plough Animal Health Corporation Carbonates of fenicol antibiotics
CN101605756A (zh) 2006-12-13 2009-12-16 先灵-普劳有限公司 氟苯尼考及其类似物的水溶性前药
CA2672598A1 (en) * 2006-12-13 2008-06-26 Schering-Plough Ltd. Water-soluble phenicol prodrugs in a lipophilic vehicle system
CA2672795A1 (en) * 2006-12-13 2008-06-26 Schering-Plough Ltd. Water-soluble prodrugs of chloramphenicol, thiamphenicol, and analogs thereof
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
ES2549731T3 (es) 2007-06-27 2015-11-02 E. I. Du Pont De Nemours And Company Método para el control de plagas en animales
US20090170954A1 (en) * 2007-12-14 2009-07-02 Schering-Plough Ltd. Process for Recovering Florfenicol and Florfenicol Analogs
CN102131772B (zh) * 2008-07-30 2015-03-11 英特威国际有限公司 用作氟苯尼考的中间体的*唑啉-保护的氨基二醇化合物的制备方法
UA110924C2 (uk) 2009-08-05 2016-03-10 Е. І. Дю Пон Де Немур Енд Компані Мезоіонні пестициди
AU2010279574A1 (en) 2009-08-05 2012-02-09 E. I. Du Pont De Nemours And Company Mesoionic pesticides
MX2012001646A (es) 2009-08-05 2012-03-21 Du Pont Pesticidas mesoionicos.
WO2012087630A1 (en) 2010-12-20 2012-06-28 E.I. Du Pont De Nemours And Company Pyridine and pyrimidine compounds for controlling invertebrate
JP2014513116A (ja) 2011-05-02 2014-05-29 ゾエティス・エルエルシー 抗菌剤として有用な新規セファロスポリン
CN103619818A (zh) 2011-06-20 2014-03-05 纳幕尔杜邦公司 用于治疗蠕虫感染的杂环化合物
TW201326128A (zh) 2011-11-28 2013-07-01 Du Pont 磺醯胺驅蟲劑
WO2013158422A1 (en) 2012-04-17 2013-10-24 E. I. Du Pont De Nemours And Company Heterocyclic compounds for controlling invertebrate pests
WO2014099837A1 (en) 2012-12-18 2014-06-26 E. I. Du Pont De Nemours And Company Sulfonamide anthelmintics
CN103242363B (zh) * 2013-04-18 2015-10-28 湖北龙翔药业有限公司 氟苯尼考磷酸二酯及盐及其制备方法
CN103923118A (zh) * 2014-04-08 2014-07-16 张家港威胜生物医药有限公司 一种水溶性氟苯尼考衍生物的合成方法
CN105111234B (zh) * 2015-09-23 2017-05-17 河北远征禾木药业有限公司 一种氟苯尼考磷酸酯的合成方法
CN110078729A (zh) * 2019-06-11 2019-08-02 石家庄学院 一种水溶性氟苯尼考前药及其制备方法
CN115286544A (zh) * 2022-10-08 2022-11-04 世华合创生物技术开发(山东)有限公司 一种氟苯尼考衍生物、制备方法及其在抗细菌感染的应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2776992A (en) * 1956-03-14 1957-01-08 Du Pont Trifluoromethylsulfonylphenyldichloracetamidopropandiol
US4235892A (en) 1979-02-05 1980-11-25 Schering Corporation, Patent Dept. 1-Aryl-2-acylamido-3-fluoro-1-propanols, methods for their use as antibacterial agents and compositions useful therefor
FR2562543B1 (fr) * 1984-04-10 1987-09-25 Elf Aquitaine Nouveaux phosphonites cycliques, leur preparation et applications
US5352832A (en) * 1992-12-18 1994-10-04 Schering Corporation Asymmetric process for preparing florfenicol, thiamphenicol chloramphenicol and oxazoline intermediates
US6864240B1 (en) * 1999-06-15 2005-03-08 Elan Pharmaceuticals, Inc. Dipeptide inhibitors of β-secretase
US6670344B2 (en) 2000-09-14 2003-12-30 Bristol-Myers Squibb Company Combretastatin A-4 phosphate prodrug mono- and di-organic amine salts, mono- and di- amino acid salts, and mono- and di-amino acid ester salts
JP2004521939A (ja) 2001-06-15 2004-07-22 アリゾナ ボード オブ リーゼンツ コンブレタスタチンａ・３プロドラッグ
WO2003077828A2 (en) 2002-03-08 2003-09-25 Schering-Plough, Ltd. Novel florfenicol-type antibiotics
US7439268B2 (en) 2003-07-18 2008-10-21 Idexx Laboratories Compositions containing prodrugs of florfenicol and methods of use
AR046970A1 (es) 2003-12-23 2006-01-04 Schering Plough Ltd Esteres de fosfato de florfenicol
US7361689B2 (en) 2003-12-31 2008-04-22 Schering-Plough Animal Health Corporation Antibacterial 1-(4-mono- and di-halomethylsulphonylphenyl)-2-acylamino-3-fluoroproponals and preparation thereof

Also Published As

Publication number Publication date
WO2005063257A1 (en) 2005-07-14
US7572777B2 (en) 2009-08-11
ZA200605165B (en) 2007-12-27
IL176342A0 (en) 2006-10-05
NO20063244L (no) 2006-09-20
MXPA06007215A (es) 2006-08-18
IL200041A0 (en) 2010-04-15
RU2006126519A (ru) 2008-01-27
JP2011148804A (ja) 2011-08-04
US20050182031A1 (en) 2005-08-18
EP1696934B1 (en) 2013-05-29
CA2550660C (en) 2011-03-15
EP1696934A1 (en) 2006-09-06
JP4719160B2 (ja) 2011-07-06
CA2550660A1 (en) 2005-07-14
TW200533640A (en) 2005-10-16
NZ547592A (en) 2009-07-31
CN100579532C (zh) 2010-01-13
US20070021387A1 (en) 2007-01-25
BRPI0418133A2 (pt) 2009-03-24
TWI262181B (en) 2006-09-21
PE20050822A1 (es) 2005-10-01
AU2004308913A1 (en) 2005-07-14
IL176342A (en) 2011-08-31
JP2007516286A (ja) 2007-06-21
AR046970A1 (es) 2006-01-04
US7153842B2 (en) 2006-12-26
KR20060111605A (ko) 2006-10-27
CN1897954A (zh) 2007-01-17

Similar Documents

Publication Publication Date Title
ECSP066670A (es) Prodroga florfenicol con mejor solubilidad en agua
AR035284A1 (es) Formulaciones en combinacion de derivados de propanol-amina sustituidos con arilo, junto con otras sustancias activas y su utilizacion
PA8553001A1 (es) Compuestos biciclicos aromaticos sustituidos con amino-alquilo, procedimiento para su preparacion y su utilizacion como medicamentos.
NI200300042A (es) Compuestos que modulan la actividad de ppar y metodos para su preparacion.
MX2020008616A (es) Rocio de fentanilo sublingual.
MX342613B (es) Geles con base de acido hialuronico que incluyen agentes anestesicos.
MX2012005365A (es) Formulaciones de tableta de liberacion inmediata.
ES2556944T3 (es) Productos fungicidas de aplicación tópica para el tratamiento de uñas
DOP2011000264A (es) Derivados de aminotetralina, composiciones farmaceuticas que los contienen y sus usos en terapia
NI201000193A (es) Formulaciones orales de análogos de citidina y métodos de uso de las mismas.
ATE349207T1 (de) Verstärkte wirkung mehrfach ungesättigter fettsäuren
MX336132B (es) Composiciones para tenido oxidativo que comprenden un 1-hexil/heptil-4,5-diaminopirazol y un benzo[1,3]dioxol-5-ilamina y derivados de estos.
CR20110568A (es) Guía con sensor
AR044888A1 (es) Formula nutritiva para la funcion optima de la barrera del intestino
AR068185A1 (es) Composiciones de tabletas de desintegracion oral de lamotrigina
EA200501819A1 (ru) Способы и фармацевтические композиции для достоверного достижения приемлемых уровней тестостерона в сыворотке
UY27419A1 (es) Formulaciones en combinación de derivados de 1,4-benzotiepina-1,1-dioxido con otras sustancias activas, y su utilización.
CY1121474T1 (el) Συνδυασμος αντιϊικων παραγοντων αμεσης δρασης και ριμπαβιρινης για την θεραπευτικη αγωγη ασθενων me hcv
CL2008003006A1 (es) Uso de ester metilico del acido (-)-(3ar,4s,7ar)-4-hidroxi-4-m-toliletinil-octahidro-indol-1-carboxilico en base libre o en forma de sal para el tratamiento, prevencion o retraso de la progresion de la disquinesia de parkinson asociada a l-dopa; uso de la composicion farmaceutica; uso de una composicion que ademas comprende l-dopa.
MX2009005228A (es) Composiciones incrustadas en matriz que tienen acidos organicos y acidos grasos.
ATE347358T1 (de) Schwimmende orale formulierungen mit kontrollierter freisetzung von betain
UY25356A1 (es) Polisacaridos de sintesis,procedimiento para su preparacion y composiciones farmaceuticas que los contienen.
HN2003000040A (es) Acidos 3-(imidazolil)-2-aminopropanoicos
BRPI0620229A8 (pt) formulação
AR050908A1 (es) Uso de benzopiranonas trisustituidas