NO20063244L - Florfenikolprolegemiddel som har forbedret vannloselighet - Google Patents

Florfenikolprolegemiddel som har forbedret vannloselighet

Info

Publication number
NO20063244L
NO20063244L NO20063244A NO20063244A NO20063244L NO 20063244 L NO20063244 L NO 20063244L NO 20063244 A NO20063244 A NO 20063244A NO 20063244 A NO20063244 A NO 20063244A NO 20063244 L NO20063244 L NO 20063244L
Authority
NO
Norway
Prior art keywords
florfenicol
water solubility
improved water
florfenicol drug
drug
Prior art date
Application number
NO20063244A
Other languages
English (en)
Inventor
Tomasz W Glinka
Scott J Hecker
Sunil V Pansare
Original Assignee
Schering Ploug Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34738768&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20063244(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Ploug Ltd filed Critical Schering Ploug Ltd
Publication of NO20063244L publication Critical patent/NO20063244L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/094—Esters of phosphoric acids with arylalkanols

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Foreliggende oppfinnelse tilkjennegir fosfatestere av florfenikol (prolegemidler) og florfenikolanaloger som har overlegen vannløselighet som blir hydrolysert til florfenikol eller den respektive florfenikolen in vivo, ved administrering til et dyr.
NO20063244A 2003-12-23 2006-07-12 Florfenikolprolegemiddel som har forbedret vannloselighet NO20063244L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53222703P 2003-12-23 2003-12-23
PCT/US2004/042591 WO2005063257A1 (en) 2003-12-23 2004-12-20 Florfenicol prodrug having improved water solubility

Publications (1)

Publication Number Publication Date
NO20063244L true NO20063244L (no) 2006-09-20

Family

ID=34738768

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20063244A NO20063244L (no) 2003-12-23 2006-07-12 Florfenikolprolegemiddel som har forbedret vannloselighet

Country Status (18)

Country Link
US (2) US7153842B2 (no)
EP (1) EP1696934B1 (no)
JP (2) JP4719160B2 (no)
KR (1) KR20060111605A (no)
CN (1) CN100579532C (no)
AR (1) AR046970A1 (no)
BR (1) BRPI0418133A2 (no)
CA (1) CA2550660C (no)
EC (1) ECSP066670A (no)
IL (2) IL176342A (no)
MX (1) MXPA06007215A (no)
NO (1) NO20063244L (no)
NZ (1) NZ547592A (no)
PE (1) PE20050822A1 (no)
RU (1) RU2006126519A (no)
TW (1) TWI262181B (no)
WO (1) WO2005063257A1 (no)
ZA (1) ZA200605165B (no)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20050386A1 (es) * 2003-05-29 2005-06-23 Schering Plough Ltd Composiciones farmaceuticas de florfenicol
US7439268B2 (en) 2003-07-18 2008-10-21 Idexx Laboratories Compositions containing prodrugs of florfenicol and methods of use
WO2005063257A1 (en) * 2003-12-23 2005-07-14 Schering-Plough Ltd. Florfenicol prodrug having improved water solubility
WO2005066119A2 (en) * 2003-12-31 2005-07-21 Schering-Plough Ltd. Antibacterial 1-(4-mono-and di-halomethylsulphonylphenyl)-2-acylamino-3-fluoropropanols and preparation thereof
WO2006034333A2 (en) 2004-09-23 2006-03-30 Schering-Plough Ltd. Control of parasites in animals by the use of novel trifluoromethanesulfonanilide oxime ether derivatives
ATE446677T1 (de) 2004-11-19 2009-11-15 Schering Plough Ltd Kontrolle von parasiten bei tieren mittels verwendung von parasitiziden 2-phenyl-3-(1h- pyrrol-2-yl) acrylonitril-derivaten
CA2609574A1 (en) * 2005-06-09 2006-12-21 Schering-Plough Ltd. Control of parasites in animals by n-[(phenyloxy)phenyl]-1,1,1-trifluoromethanesulfonamide and n-[(phenylsulfanyl)phenyl]-1,1,1-trifluoromethanesulfonamide derivatives
US8119667B2 (en) * 2005-12-29 2012-02-21 Schering-Plough Animal Health Corporation Carbonates of fenicol antibiotics
CA2672586A1 (en) * 2006-12-13 2008-06-26 Schering-Plough Ltd. Water-soluble prodrugs of florfenicol and its analogs
WO2008076256A1 (en) * 2006-12-13 2008-06-26 Schering-Plough Ltd. Water-soluble prodrugs of chloramphenicol, thiamphenicol, and analogs thereof
CN101600422A (zh) * 2006-12-13 2009-12-09 先灵-普劳有限公司 在亲脂性溶媒系统中的水溶性苯丙醇前药
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
PT2957284T (pt) 2007-06-27 2018-04-23 Du Pont Método de controlo de pragas em animais
PE20091171A1 (es) * 2007-12-14 2009-08-03 Schering Plough Ltd Proceso para recuperar florfenicol y analogos de florfenicol
CN102131772B (zh) * 2008-07-30 2015-03-11 英特威国际有限公司 用作氟苯尼考的中间体的*唑啉-保护的氨基二醇化合物的制备方法
UA110924C2 (uk) 2009-08-05 2016-03-10 Е. І. Дю Пон Де Немур Енд Компані Мезоіонні пестициди
AU2010279574A1 (en) 2009-08-05 2012-02-09 E. I. Du Pont De Nemours And Company Mesoionic pesticides
MX2012001646A (es) 2009-08-05 2012-03-21 Du Pont Pesticidas mesoionicos.
WO2012087630A1 (en) 2010-12-20 2012-06-28 E.I. Du Pont De Nemours And Company Pyridine and pyrimidine compounds for controlling invertebrate
CN103649097A (zh) 2011-05-02 2014-03-19 佐蒂斯有限责任公司 用作抗菌剂的新型头孢菌素类
BR112013032813A2 (pt) 2011-06-20 2016-08-16 Du Pont composto de fórmula, composição e método para o tratamento, controle, prevenção ou proteção dos animais contra a infecção por helmintos
CA2855001A1 (en) 2011-11-28 2013-06-06 E.I. Du Pont De Nemours And Company N- (4 -quinolinylmethyl) sulfonamide derivatives and their use as anthelmintics
WO2013158422A1 (en) 2012-04-17 2013-10-24 E. I. Du Pont De Nemours And Company Heterocyclic compounds for controlling invertebrate pests
WO2014099837A1 (en) 2012-12-18 2014-06-26 E. I. Du Pont De Nemours And Company Sulfonamide anthelmintics
CN103242363B (zh) * 2013-04-18 2015-10-28 湖北龙翔药业有限公司 氟苯尼考磷酸二酯及盐及其制备方法
CN103923118A (zh) * 2014-04-08 2014-07-16 张家港威胜生物医药有限公司 一种水溶性氟苯尼考衍生物的合成方法
CN105111234B (zh) * 2015-09-23 2017-05-17 河北远征禾木药业有限公司 一种氟苯尼考磷酸酯的合成方法
CN110078729A (zh) * 2019-06-11 2019-08-02 石家庄学院 一种水溶性氟苯尼考前药及其制备方法
CN115286544A (zh) * 2022-10-08 2022-11-04 世华合创生物技术开发(山东)有限公司 一种氟苯尼考衍生物、制备方法及其在抗细菌感染的应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2776992A (en) 1956-03-14 1957-01-08 Du Pont Trifluoromethylsulfonylphenyldichloracetamidopropandiol
US4235892A (en) * 1979-02-05 1980-11-25 Schering Corporation, Patent Dept. 1-Aryl-2-acylamido-3-fluoro-1-propanols, methods for their use as antibacterial agents and compositions useful therefor
FR2562543B1 (fr) * 1984-04-10 1987-09-25 Elf Aquitaine Nouveaux phosphonites cycliques, leur preparation et applications
US5352832A (en) 1992-12-18 1994-10-04 Schering Corporation Asymmetric process for preparing florfenicol, thiamphenicol chloramphenicol and oxazoline intermediates
US6864240B1 (en) 1999-06-15 2005-03-08 Elan Pharmaceuticals, Inc. Dipeptide inhibitors of β-secretase
US6670344B2 (en) 2000-09-14 2003-12-30 Bristol-Myers Squibb Company Combretastatin A-4 phosphate prodrug mono- and di-organic amine salts, mono- and di- amino acid salts, and mono- and di-amino acid ester salts
US7547686B2 (en) 2001-06-15 2009-06-16 Arizona Board of Regents, a body corporate of the State of Arizona, Acting for and on Behalf of the Arizona State University Combretastatin A-3 prodrug
WO2003077828A2 (en) * 2002-03-08 2003-09-25 Schering-Plough, Ltd. Novel florfenicol-type antibiotics
US7439268B2 (en) * 2003-07-18 2008-10-21 Idexx Laboratories Compositions containing prodrugs of florfenicol and methods of use
WO2005063257A1 (en) 2003-12-23 2005-07-14 Schering-Plough Ltd. Florfenicol prodrug having improved water solubility
WO2005066119A2 (en) 2003-12-31 2005-07-21 Schering-Plough Ltd. Antibacterial 1-(4-mono-and di-halomethylsulphonylphenyl)-2-acylamino-3-fluoropropanols and preparation thereof

Also Published As

Publication number Publication date
ECSP066670A (es) 2006-10-25
IL200041A0 (en) 2010-04-15
RU2006126519A (ru) 2008-01-27
TW200533640A (en) 2005-10-16
KR20060111605A (ko) 2006-10-27
WO2005063257A1 (en) 2005-07-14
US20050182031A1 (en) 2005-08-18
CN100579532C (zh) 2010-01-13
CA2550660C (en) 2011-03-15
US20070021387A1 (en) 2007-01-25
NZ547592A (en) 2009-07-31
EP1696934B1 (en) 2013-05-29
IL176342A0 (en) 2006-10-05
US7572777B2 (en) 2009-08-11
IL176342A (en) 2011-08-31
ZA200605165B (en) 2007-12-27
CN1897954A (zh) 2007-01-17
AU2004308913A1 (en) 2005-07-14
MXPA06007215A (es) 2006-08-18
CA2550660A1 (en) 2005-07-14
JP4719160B2 (ja) 2011-07-06
EP1696934A1 (en) 2006-09-06
TWI262181B (en) 2006-09-21
JP2011148804A (ja) 2011-08-04
PE20050822A1 (es) 2005-10-01
BRPI0418133A2 (pt) 2009-03-24
US7153842B2 (en) 2006-12-26
JP2007516286A (ja) 2007-06-21
AR046970A1 (es) 2006-01-04

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