NO20090596L - Antivirale fosfinatforbindelser - Google Patents
Antivirale fosfinatforbindelserInfo
- Publication number
- NO20090596L NO20090596L NO20090596A NO20090596A NO20090596L NO 20090596 L NO20090596 L NO 20090596L NO 20090596 A NO20090596 A NO 20090596A NO 20090596 A NO20090596 A NO 20090596A NO 20090596 L NO20090596 L NO 20090596L
- Authority
- NO
- Norway
- Prior art keywords
- compounds
- phosphinate compounds
- antiviral
- antiviral phosphinate
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Abstract
Oppfinnelsen vedrører antivirale fosfinatforbindelser, preparater som inneholder slike forbindelser, og terapeutiske fremgangsmåter som omfatter administreringen av slike forbindelser, samt fremgangsmåter og mellomprodukter som kan anvendes til fremstilling av slike forbindelser.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US81948806P | 2006-07-07 | 2006-07-07 | |
US83290806P | 2006-07-24 | 2006-07-24 | |
PCT/US2007/015664 WO2008005565A2 (en) | 2006-07-07 | 2007-07-06 | Antiviral phosphinate compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20090596L true NO20090596L (no) | 2009-04-01 |
Family
ID=38626760
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20090596A NO20090596L (no) | 2006-07-07 | 2009-02-06 | Antivirale fosfinatforbindelser |
Country Status (20)
Country | Link |
---|---|
US (4) | US7893264B2 (no) |
EP (2) | EP2422791B1 (no) |
JP (3) | JP2009542698A (no) |
KR (1) | KR20090026216A (no) |
CN (1) | CN102532198A (no) |
AR (1) | AR061840A1 (no) |
AT (1) | ATE554776T1 (no) |
AU (1) | AU2007269567B2 (no) |
BR (1) | BRPI0713961A2 (no) |
CA (1) | CA2656356C (no) |
EA (1) | EA018098B1 (no) |
ES (2) | ES2388969T3 (no) |
HK (1) | HK1127295A1 (no) |
HR (1) | HRP20090076A2 (no) |
IL (1) | IL195489A0 (no) |
MX (1) | MX2009000236A (no) |
NO (1) | NO20090596L (no) |
TW (1) | TW200819460A (no) |
WO (1) | WO2008005565A2 (no) |
ZA (1) | ZA200810400B (no) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2008152171A (ru) * | 2006-07-05 | 2010-08-10 | Интермьюн, Инк. (Us) | Новые ингибиторы вирусной репликации гепатита с |
AR061840A1 (es) * | 2006-07-07 | 2008-09-24 | Gilead Sciences Inc | Compuestos fosfinatos antivirales |
BRPI0911260A2 (pt) * | 2008-04-15 | 2015-09-29 | Intermune Inc | composto, composição farmacêutica, método de inibição de atividade da protease de ns3/ns4 in, vitro e usos de compostos |
US8193372B2 (en) | 2009-03-04 | 2012-06-05 | Idenix Pharmaceuticals, Inc. | Phosphothiophene and phosphothiazole HCV polymerase inhibitors |
TW201111381A (en) * | 2009-06-23 | 2011-04-01 | Gilead Sciences Inc | Pharmaceutical combinations useful for treating HCV |
US8476225B2 (en) | 2009-12-04 | 2013-07-02 | Gilead Sciences, Inc. | Antiviral compounds |
WO2011156757A1 (en) * | 2010-06-10 | 2011-12-15 | Gilead Sciences, Inc. | Combination of anti-hcv compounds with ribavirin for the treatment of hcv |
CA2822037A1 (en) | 2010-12-20 | 2012-06-28 | Gilead Sciences, Inc. | Methods for treating hcv |
US8957203B2 (en) | 2011-05-05 | 2015-02-17 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
US8691757B2 (en) | 2011-06-15 | 2014-04-08 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
MD4589C1 (ro) | 2011-09-16 | 2019-03-31 | Gilead Pharmasset Llc | Compoziţie farmaceutică cu conţinut de sofosbuvir şi utilizarea acesteia în tratamentul hepatitei virale C |
US8466159B2 (en) | 2011-10-21 | 2013-06-18 | Abbvie Inc. | Methods for treating HCV |
US8853176B2 (en) | 2011-10-21 | 2014-10-07 | Abbvie Inc. | Methods for treating HCV |
GB2515942A (en) | 2011-10-21 | 2015-01-07 | Abbvie Inc | Combination treatment (e.g. with ABT-072 or ABT-333) of DAAs for use in treating HCV |
US8492386B2 (en) | 2011-10-21 | 2013-07-23 | Abbvie Inc. | Methods for treating HCV |
PT2909205T (pt) | 2012-10-19 | 2017-02-06 | Bristol Myers Squibb Co | Derivados de carbamato de hexadecahidrociclopropa(e)pirrolo(1,2- a)(1,4)diazaciclopentadecinilo substituídos com 9-metilo como inibidores da protease não estrutural 3 (ns3) para o tratamento de infeções por vírus da hepatite c |
US9643999B2 (en) | 2012-11-02 | 2017-05-09 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
US9598433B2 (en) | 2012-11-02 | 2017-03-21 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
US9334279B2 (en) | 2012-11-02 | 2016-05-10 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
US9409943B2 (en) | 2012-11-05 | 2016-08-09 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
NZ625087A (en) | 2013-01-31 | 2017-05-26 | Gilead Pharmasset Llc | Combination formulation of two antiviral compounds |
JP6342922B2 (ja) | 2013-03-07 | 2018-06-13 | ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company | C型肝炎ウイルス阻害剤 |
CN103539833B (zh) * | 2013-09-29 | 2016-02-03 | 北京林业大学 | 高活性α-葡萄糖苷酶抑制肽及其制备方法和用途 |
CN103539831B (zh) * | 2013-09-29 | 2016-02-03 | 北京林业大学 | 山杏α-葡萄糖苷酶抑制肽及其制备方法和用途 |
WO2017189978A1 (en) | 2016-04-28 | 2017-11-02 | Emory University | Alkyne containing nucleotide and nucleoside therapeutic compositions and uses related thereto |
MX2018014377A (es) | 2016-05-27 | 2019-03-14 | Gilead Sciences Inc | Metodos para tratar infecciones por virus de hepatitis b usando inhibidores de proteina no estructural 5a (ns5a), proteina no estructural 5b (ns5b) o proteina no estructural 3 (ns3). |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4816570A (en) | 1982-11-30 | 1989-03-28 | The Board Of Regents Of The University Of Texas System | Biologically reversible phosphate and phosphonate protective groups |
US4968788A (en) * | 1986-04-04 | 1990-11-06 | Board Of Regents, The University Of Texas System | Biologically reversible phosphate and phosphonate protective gruops |
CA2083386C (en) | 1990-06-13 | 1999-02-16 | Arnold Glazier | Phosphorous prodrugs |
EP0481214B1 (en) | 1990-09-14 | 1998-06-24 | Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic | Prodrugs of phosphonates |
DE4308096A1 (de) | 1993-03-13 | 1994-09-15 | Hoechst Ag | Prodrug-Derivate von Enzyminhibitoren mit Hydroxylgruppen, Verfahren zu deren Herstellung und ihre Verwendung |
ATE199906T1 (de) | 1993-06-29 | 2001-04-15 | Mitsubishi Chem Corp | Phosphonat-nukleotid ester-derivate |
AU691527B2 (en) | 1993-09-17 | 1998-05-21 | Gilead Sciences, Inc. | Nucleotide analogs |
JPH07183249A (ja) * | 1993-12-22 | 1995-07-21 | Nec Yamagata Ltd | イオン注入工程管理方法 |
US5543523A (en) | 1994-11-15 | 1996-08-06 | Regents Of The University Of Minnesota | Method and intermediates for the synthesis of korupensamines |
US5968788A (en) * | 1995-08-28 | 1999-10-19 | Toray Industries, Inc. | Method for producing folic acid |
US6004977A (en) * | 1996-12-27 | 1999-12-21 | Hoechst Marion Roussel, Inc. | N-(pyridinylamino) isoindolines and related compounds |
DE19843360A1 (de) * | 1998-09-22 | 2000-03-30 | Hassan Jomaa | Phosphororganische Verbindungen und ihre Verwendung |
US6828301B2 (en) * | 2002-02-07 | 2004-12-07 | Boehringer Ingelheim International Gmbh | Pharmaceutical compositions for hepatitis C viral protease inhibitors |
WO2004094452A2 (en) * | 2003-04-16 | 2004-11-04 | Bristol-Myers Squibb Company | Macrocyclic isoquinoline peptide inhibitors of hepatitis c virus |
BRPI0513426A (pt) | 2004-07-16 | 2007-11-27 | Gilead Sciences Inc | processo de preparação de amino ácidos úteis na preparação de moduladores de receptores de peptìdeos |
WO2007001406A2 (en) | 2004-10-05 | 2007-01-04 | Chiron Corporation | Aryl-containing macrocyclic compounds |
MX2007012659A (es) | 2005-04-13 | 2008-01-11 | Astex Therapeutics Ltd | Derivados de hidroxi-benzamida y su uso como inhibidores de hsp90. |
EP2305695A3 (en) | 2005-07-25 | 2011-07-27 | Intermune, Inc. | Macrocyclic inhibitors of Hepatitis C virus replication |
DK1919898T3 (da) * | 2005-07-29 | 2011-05-02 | Tibotec Pharm Ltd | Makrocykliske inhibitorer af hepatitis-C-virus |
PE20070211A1 (es) | 2005-07-29 | 2007-05-12 | Medivir Ab | Compuestos macrociclicos como inhibidores del virus de hepatitis c |
US7772183B2 (en) * | 2005-10-12 | 2010-08-10 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
AR061840A1 (es) * | 2006-07-07 | 2008-09-24 | Gilead Sciences Inc | Compuestos fosfinatos antivirales |
US8293705B2 (en) | 2007-12-21 | 2012-10-23 | Avila Therapeutics, Inc. | HCV protease inhibitors and uses thereof |
TW201111381A (en) | 2009-06-23 | 2011-04-01 | Gilead Sciences Inc | Pharmaceutical combinations useful for treating HCV |
US8691757B2 (en) | 2011-06-15 | 2014-04-08 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
-
2007
- 2007-07-06 AR ARP070103031A patent/AR061840A1/es not_active Application Discontinuation
- 2007-07-06 ES ES07796752T patent/ES2388969T3/es active Active
- 2007-07-06 WO PCT/US2007/015664 patent/WO2008005565A2/en active Application Filing
- 2007-07-06 BR BRPI0713961-6A patent/BRPI0713961A2/pt not_active IP Right Cessation
- 2007-07-06 EP EP11190674.9A patent/EP2422791B1/en active Active
- 2007-07-06 KR KR1020097002642A patent/KR20090026216A/ko not_active Application Discontinuation
- 2007-07-06 US US11/825,606 patent/US7893264B2/en active Active
- 2007-07-06 JP JP2009518397A patent/JP2009542698A/ja not_active Withdrawn
- 2007-07-06 ES ES11190674T patent/ES2531315T3/es active Active
- 2007-07-06 CN CN2011104294087A patent/CN102532198A/zh active Pending
- 2007-07-06 EA EA200900154A patent/EA018098B1/ru not_active IP Right Cessation
- 2007-07-06 AT AT07796752T patent/ATE554776T1/de active
- 2007-07-06 EP EP07796752A patent/EP2043658B1/en active Active
- 2007-07-06 AU AU2007269567A patent/AU2007269567B2/en not_active Ceased
- 2007-07-06 MX MX2009000236A patent/MX2009000236A/es active IP Right Grant
- 2007-07-06 US US12/303,219 patent/US20090227491A1/en not_active Abandoned
- 2007-07-06 CA CA2656356A patent/CA2656356C/en not_active Expired - Fee Related
- 2007-07-06 TW TW096124722A patent/TW200819460A/zh unknown
-
2008
- 2008-11-25 IL IL195489A patent/IL195489A0/en unknown
- 2008-12-09 ZA ZA2008/10400A patent/ZA200810400B/en unknown
-
2009
- 2009-02-06 HR HR20090076A patent/HRP20090076A2/xx not_active Application Discontinuation
- 2009-02-06 NO NO20090596A patent/NO20090596L/no not_active Application Discontinuation
- 2009-07-16 HK HK09106472.5A patent/HK1127295A1/xx not_active IP Right Cessation
-
2010
- 2010-10-27 US US12/913,692 patent/US8674088B2/en active Active
- 2010-10-27 US US12/913,704 patent/US8586744B2/en active Active
-
2012
- 2012-02-28 JP JP2012041605A patent/JP2012107061A/ja not_active Withdrawn
-
2015
- 2015-01-22 JP JP2015010367A patent/JP6010640B2/ja not_active Expired - Fee Related
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20090596L (no) | Antivirale fosfinatforbindelser | |
NO20071078L (no) | Antivirale forbindelser | |
NO20070866L (no) | Antivirale forbindelser. | |
CY1119669T1 (el) | Παραγωγα 1-φαινυλ-2-πυριδινυλ-αλκυλ-αλκοολων ως αναστολεις φωσφοδιεστερασης | |
MY153915A (en) | Organic compounds | |
MA33803B1 (fr) | Inhibiteur de bromodomaine de benzodiazépine | |
NO20055612L (no) | Anti-inflammatoriske fosfonatforbindelser | |
DK2089369T3 (da) | 2,4-pyrimidindiaminderivater som hæmmere af JAK-kinaser til behandling af autoimmune sygdomme | |
MXPA06011327A (es) | Azaindoles utiles como inhibidores de jak y otras proteinas cinasas. | |
MX2009007944A (es) | Compuestos y composiciones de purina como inhibidores de quinasa para el tratamiento de enfermedades relacionadas con plasmodium. | |
JO2778B1 (en) | Certain vehicles, installations and methods | |
MX2008011976A (es) | Composiciones farmaceuticas. | |
EA200971051A1 (ru) | Ингибиторы p70 s6 киназы | |
TW201713640A (en) | Bruton's tyrosine kinase inhibitors | |
EA200970156A1 (ru) | Пиридизиноновые производные | |
WO2009152356A3 (en) | Compounds and compositions useful for the treatment of malaria | |
EA201390609A1 (ru) | ПРОИЗВОДНЫЕ ГИДАНТОИНА, ПОЛЕЗНЫЕ В КАЧЕСТВЕ ИНГИБИТОРОВ Kv3-КАНАЛОВ | |
EA200901166A1 (ru) | Соединения и композиции в качестве модуляторов активности gpr 119 | |
TN2009000291A1 (en) | Inhibitors of mek | |
NO20090783L (no) | Pyrimidonforbindelser som inhibitorer av GSK-3 | |
MX2009010207A (es) | Peptidos de hidrazido como inhibidores de proteasa ns3 de virus de hepatitis c. | |
WO2010048358A3 (en) | Ethoxyphenylmethyl inhibitors of sglt2 | |
UA94749C2 (en) | Benzimidazole modulators of vr1 | |
MX2009004862A (es) | Estabilizacion de vacunas por liofilizacion. | |
BRPI1015043A2 (pt) | derivados de diazahomoadamantano e métodos de uso dos mesmos |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |