HN2003000040A - Acidos 3-(imidazolil)-2-aminopropanoicos - Google Patents

Acidos 3-(imidazolil)-2-aminopropanoicos

Info

Publication number
HN2003000040A
HN2003000040A HN2003000040A HN2003000040A HN2003000040A HN 2003000040 A HN2003000040 A HN 2003000040A HN 2003000040 A HN2003000040 A HN 2003000040A HN 2003000040 A HN2003000040 A HN 2003000040A HN 2003000040 A HN2003000040 A HN 2003000040A
Authority
HN
Honduras
Prior art keywords
imidazolil
aminopropanoics
acids
aamino
tafia
Prior art date
Application number
HN2003000040A
Other languages
English (en)
Inventor
Charlotte Moira Norfor Allerton
Mark Edward Bunnage
John Steele
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0201387A external-priority patent/GB0201387D0/en
Priority claimed from GB0201911A external-priority patent/GB0201911D0/en
Application filed by Pfizer filed Critical Pfizer
Publication of HN2003000040A publication Critical patent/HN2003000040A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

LA PRESENTE INVENCION SE REFIEREA UNA SERIE DE NUEVOS DERIVADOS DEL ACIDO 3-(IMIDAZOLIL)-2-(3'-AAMINO-POLIMETILENIMINO)PROPANOICO QUE SON INHIBIDORES DE LOS TAFIA Y SON UTILES EN EL TRATAMIENTO DE ENFERMEDADES.
HN2003000040A 2002-01-22 2003-01-21 Acidos 3-(imidazolil)-2-aminopropanoicos HN2003000040A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0201387A GB0201387D0 (en) 2002-01-22 2002-01-22 3-(imidazolyl)-2-aminopropanoic acids
GB0201911A GB0201911D0 (en) 2002-01-28 2002-01-28 3-(Imidazolyl)-2-Aminopropanoic acids

Publications (1)

Publication Number Publication Date
HN2003000040A true HN2003000040A (es) 2003-08-01

Family

ID=27614791

Family Applications (1)

Application Number Title Priority Date Filing Date
HN2003000040A HN2003000040A (es) 2002-01-22 2003-01-21 Acidos 3-(imidazolil)-2-aminopropanoicos

Country Status (11)

Country Link
US (2) US6759426B2 (es)
EP (1) EP1467732A1 (es)
JP (1) JP2005516972A (es)
BR (1) BR0307033A (es)
CA (1) CA2472239A1 (es)
HN (1) HN2003000040A (es)
MX (1) MXPA04005940A (es)
PA (1) PA8563601A1 (es)
PE (1) PE20030858A1 (es)
TW (1) TW200302093A (es)
WO (1) WO2003061653A1 (es)

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* Cited by examiner, † Cited by third party
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BR0307033A (pt) * 2002-01-22 2004-12-07 Pfizer ácidos 3-(imidazolil)-2-aminopropanóicos para o uso como inibidores tafi-a para o tratamento de doenças trombóticas
WO2004019882A2 (en) * 2002-08-29 2004-03-11 American Diagnostica, Inc. METHODS OF SCREENING FOR COMPOUNDS THAT MODULATE TAFIa ACTIVITY, COMPOUNDS, AND METHODS OF USING THE COMPOUNDS
US8710232B2 (en) 2004-04-22 2014-04-29 Sanofi-Aventis Deutschland Gmbh Imidazole derivatives used as TAFIa inhibitors
DE102004020186A1 (de) 2004-04-22 2005-11-17 Aventis Pharma Deutschland Gmbh Heterocyclylessigsäuren als Inhibitoren von TAFla
JP4046708B2 (ja) * 2004-06-04 2008-02-13 明治製菓株式会社 ３−アルケニルセフェム化合物の製造方法
US20060105995A1 (en) * 2004-10-05 2006-05-18 Schering Aktiengesellschaft TAFI inhibitors and their use to treat pulmonary fibrosis
WO2006113247A1 (en) * 2005-04-18 2006-10-26 Bayer Schering Pharma Aktiengesellschaft Use of tafi inhibitors for enhanced myocardial reperfusion and facilitated pci
DE102005049385A1 (de) 2005-10-15 2007-04-19 Sanofi-Aventis Deutschland Gmbh Imidazolderivate als Inhibitoren von TAFIa
WO2010050525A1 (ja) 2008-10-29 2010-05-06 大正製薬株式会社 ＴＡＦＩａ阻害活性を有する化合物
AR078424A1 (es) * 2009-09-17 2011-11-09 Taisho Pharmaceutical Co Ltd Derivados de dihidroimidazoquinolina con actividad inhibitoria de tafia, composiciones farmaceuticas que los contienen y su uso como agentes terapeuticos o profilacticos para enfermedades tromboticas
RU2572814C2 (ru) 2010-03-18 2016-01-20 Дайити Санкио Компани, Лимитед ЦИКЛОАЛКИЛ-ЗАМЕЩЕННОЕ ПРОИЗВОДНОЕ ИМИДАЗОЛА, ОБЛАДАЮЩЕЕ ИНГИБИРУЮЩЕЙ АКТИВНОСТЬЮ В ОТНОШЕНИИ TAFIa
KR20130006620A (ko) * 2010-03-18 2013-01-17 다이이찌 산쿄 가부시키가이샤 시클로프로판카르복실산 유도체
AU2011328263A1 (en) 2010-11-11 2013-05-30 Sanofi Process for the preparation of 3-(6-amino-pyridin-3yl)-2-acrylic acid derivatives
RU2015156612A (ru) 2013-06-10 2017-07-17 Санофи Макроциклические производные мочевины в качестве ингибиторов tafia, их получение и их применение в качестве фармацевтических средств
WO2017170460A1 (ja) 2016-03-29 2017-10-05 第一三共株式会社 炎症性腸疾患治療剤

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Also Published As

Publication number Publication date
PA8563601A1 (es) 2003-12-10
MXPA04005940A (es) 2004-09-13
TW200302093A (en) 2003-08-01
US20040192668A1 (en) 2004-09-30
PE20030858A1 (es) 2003-10-21
WO2003061653A1 (en) 2003-07-31
WO2003061653A9 (en) 2003-12-24
US6919457B2 (en) 2005-07-19
US6759426B2 (en) 2004-07-06
JP2005516972A (ja) 2005-06-09
CA2472239A1 (en) 2003-07-31
BR0307033A (pt) 2004-12-07
EP1467732A1 (en) 2004-10-20
US20030191107A1 (en) 2003-10-09

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