EA201691731A1 - Амидные соединения для лечения опосредованных комплементом нарушений - Google Patents

Амидные соединения для лечения опосредованных комплементом нарушений

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Publication number
EA201691731A1
EA201691731A1 EA201691731A EA201691731A EA201691731A1 EA 201691731 A1 EA201691731 A1 EA 201691731A1 EA 201691731 A EA201691731 A EA 201691731A EA 201691731 A EA201691731 A EA 201691731A EA 201691731 A1 EA201691731 A1 EA 201691731A1
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EA
Eurasian Patent Office
Prior art keywords
complement
factor
activation
distributions
mediated
Prior art date
Application number
EA201691731A
Other languages
English (en)
Russian (ru)
Inventor
Цюпин Ван
Венкат Рао Гадхачанда
Годвин Пэйс
Акихиро Хашимото
Давей Чэнь
Сянчжу Ван
Атул Агарвал
Милинд Дешпанде
Авинаш С. Фадке
Джейсон Аллан Вайлс
Original Assignee
Ачиллион Фармасьютикалс, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ачиллион Фармасьютикалс, Инк. filed Critical Ачиллион Фармасьютикалс, Инк.
Publication of EA201691731A1 publication Critical patent/EA201691731A1/ru

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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