EA201491752A1 - Вакцина против rsv - Google Patents

Вакцина против rsv

Info

Publication number
EA201491752A1
EA201491752A1 EA201491752A EA201491752A EA201491752A1 EA 201491752 A1 EA201491752 A1 EA 201491752A1 EA 201491752 A EA201491752 A EA 201491752A EA 201491752 A EA201491752 A EA 201491752A EA 201491752 A1 EA201491752 A1 EA 201491752A1
Authority
EA
Eurasian Patent Office
Prior art keywords
vaccine against
against rsv
rsv
vaccine
nucleic acid
Prior art date
Application number
EA201491752A
Other languages
English (en)
Other versions
EA026620B1 (ru
Inventor
Катарина Радошевич
Жером Х.Х.В. Кустерс
Йорт Веллинга
Мира Н. Виджожоатмоджо
Original Assignee
Круселл Холланд Б.В.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Круселл Холланд Б.В. filed Critical Круселл Холланд Б.В.
Publication of EA201491752A1 publication Critical patent/EA201491752A1/ru
Publication of EA026620B1 publication Critical patent/EA026620B1/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/155Paramyxoviridae, e.g. parainfluenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5256Virus expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/543Mucosal route intranasal
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18511Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18534Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Настоящее изобретение предлагает вакцину против респираторно-синцитиального вируса (RSV), содержащую рекомбинантный аденовирус человека серотипа, который содержит нуклеиновую кислоту, кодирующую белок F RSV или его иммунологически активную часть.
EA201491752A 2012-03-22 2013-03-21 Вакцина против rsv EA026620B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261614429P 2012-03-22 2012-03-22
EP12160682 2012-03-22
PCT/EP2013/055943 WO2013139916A1 (en) 2012-03-22 2013-03-21 Vaccine against rsv

Publications (2)

Publication Number Publication Date
EA201491752A1 true EA201491752A1 (ru) 2015-02-27
EA026620B1 EA026620B1 (ru) 2017-04-28

Family

ID=49221877

Family Applications (2)

Application Number Title Priority Date Filing Date
EA201491752A EA026620B1 (ru) 2012-03-22 2013-03-21 Вакцина против rsv
EA201491754A EA026504B1 (ru) 2012-03-22 2013-03-21 Вакцина против rsv

Family Applications After (1)

Application Number Title Priority Date Filing Date
EA201491754A EA026504B1 (ru) 2012-03-22 2013-03-21 Вакцина против rsv

Country Status (15)

Country Link
EP (2) EP2827894B1 (ru)
JP (2) JP5845376B2 (ru)
KR (2) KR102023791B1 (ru)
CN (2) CN105431169B (ru)
AP (2) AP2014007993A0 (ru)
AR (2) AR090470A1 (ru)
AU (2) AU2013237424B2 (ru)
BR (1) BR112014023196B1 (ru)
CA (2) CA2867950C (ru)
EA (2) EA026620B1 (ru)
MY (2) MY169352A (ru)
NZ (2) NZ630753A (ru)
SG (2) SG11201405803PA (ru)
TW (2) TWI640534B (ru)
WO (2) WO2013139916A1 (ru)

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EP3624844A1 (en) * 2017-05-17 2020-03-25 Janssen Vaccines & Prevention B.V. Methods and compositions for inducing protective immunity against rsv infection
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WO2020229579A1 (en) * 2019-05-15 2020-11-19 Janssen Vaccines & Prevention B.V. Prophylactic treatment of respiratory syncytial virus infection with an adenovirus based vaccine
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EP4003414A4 (en) * 2020-08-22 2023-05-10 Fed. State Budgetary Institution "Nat. Res. Centre for Epidemiology and Microbiology named after the Honorary Academician N.F. Gamaleya" of the .... MEDICATIONS TO INDUCE SPECIFIC IMMUNITY AGAINST SARS-COV-2
RU2731342C9 (ru) * 2020-08-22 2021-10-05 федеральное государственное бюджетное учреждение "Национальный исследовательский центр эпидемиологии и микробиологии имени почетного академика Н.Ф. Гамалеи" Министерства здравоохранения Российской Федерации Фармацевтическое средство и способ его использования для индукции специфического иммунитета против вируса тяжелого острого респираторного синдрома SARS-CoV-2 (варианты)
EP4010018A4 (en) * 2020-08-22 2022-11-09 Fed. State Budgetary Institution "Nat. Res. Centre for Epidemiology and Microbiology named after the Honorary Academician N.F. Gamaleya" of the .... EXPRESSION VECTOR AGAINST SEVERE ACUTE RESPIRATORY SYNDROME SARS-COV-2 VIRUS
RU2731356C9 (ru) * 2020-08-22 2021-10-05 федеральное государственное бюджетное учреждение "Национальный исследовательский центр эпидемиологии и микробиологии имени почетного академика Н.Ф. Гамалеи" Министерства здравоохранения Российской Федерации Экспрессионный вектор для создания иммунобиологического средства для индукции специфического иммунитета против вируса тяжелого острого респираторного синдрома SARS-CoV-2 (варианты)
CN112220921B (zh) * 2020-08-25 2022-08-16 北京交通大学 一种针对呼吸道合胞病毒感染的组合疫苗
CN112226444B (zh) * 2020-08-25 2022-11-04 北京交通大学 呼吸道合胞病毒全长融合前融合糖蛋白核苷酸序列、重组腺病毒载体及其应用产品
WO2022215436A1 (ja) * 2021-04-05 2022-10-13 株式会社クボタ 管理機制御システム
WO2023217189A2 (zh) * 2022-05-10 2023-11-16 康希诺生物股份公司 一种呼吸道合胞病毒腺病毒载体疫苗及其制备方法和应用
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Also Published As

Publication number Publication date
TW201343669A (zh) 2013-11-01
AU2013237424A1 (en) 2014-10-16
EA201491754A1 (ru) 2014-12-30
KR20140138765A (ko) 2014-12-04
AP2014007993A0 (en) 2014-10-31
WO2013139916A1 (en) 2013-09-26
KR102023791B1 (ko) 2019-09-23
TWI640534B (zh) 2018-11-11
AP2014007994A0 (en) 2014-10-31
KR20140138769A (ko) 2014-12-04
CN104334188A (zh) 2015-02-04
EP2827894A1 (en) 2015-01-28
TWI624545B (zh) 2018-05-21
JP2015519295A (ja) 2015-07-09
NZ630649A (en) 2016-12-23
EP2827895A1 (en) 2015-01-28
BR112014023196A2 (ru) 2017-06-20
KR102050616B1 (ko) 2019-12-03
MY169331A (en) 2019-03-21
MY169352A (en) 2019-03-25
EA026504B1 (ru) 2017-04-28
BR112014023196B1 (pt) 2021-09-08
AU2013237429A1 (en) 2014-10-09
CN105431169A (zh) 2016-03-23
CA2867955C (en) 2023-02-07
SG11201405803PA (en) 2014-11-27
CN104334188B (zh) 2016-08-24
CA2867950A1 (en) 2013-09-26
CA2867955A1 (en) 2013-09-26
NZ630753A (en) 2016-12-23
EP2827894B1 (en) 2017-05-17
AU2013237429B2 (en) 2015-07-23
JP5805908B2 (ja) 2015-11-10
SG11201405804YA (en) 2014-10-30
JP2015512380A (ja) 2015-04-27
EP2827895B1 (en) 2017-08-09
WO2013139911A1 (en) 2013-09-26
AR090469A1 (es) 2014-11-12
CA2867950C (en) 2023-02-21
TW201341531A (zh) 2013-10-16
AU2013237424B2 (en) 2017-07-06
JP5845376B2 (ja) 2016-01-20
CN105431169B (zh) 2019-04-02
EA026620B1 (ru) 2017-04-28
AR090470A1 (es) 2014-11-12

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