EA201070835A1 - Состав капсулы - Google Patents

Состав капсулы

Info

Publication number
EA201070835A1
EA201070835A1 EA201070835A EA201070835A EA201070835A1 EA 201070835 A1 EA201070835 A1 EA 201070835A1 EA 201070835 A EA201070835 A EA 201070835A EA 201070835 A EA201070835 A EA 201070835A EA 201070835 A1 EA201070835 A1 EA 201070835A1
Authority
EA
Eurasian Patent Office
Prior art keywords
pharmaceutically active
liquid
active ingredient
solid
composition capsules
Prior art date
Application number
EA201070835A
Other languages
English (en)
Inventor
Йосихиро Утияма
Томохиро Йосинари
Original Assignee
Такеда Фармасьютикал Компани Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Такеда Фармасьютикал Компани Лимитед filed Critical Такеда Фармасьютикал Компани Лимитед
Publication of EA201070835A1 publication Critical patent/EA201070835A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release

Abstract

Изобретение относится к следующему препарату капсул, который обладает превосходной растворимостью и т.п. фармацевтически активного ингредиента и содержит жидкий и твердый фармацевтические ингредиенты: бесшовной капсуле, содержащий жидкие и твердые фармацевтически активные ингредиенты, в которой жидкий фармацевтически активный ингредиент заключен в капсулу в форме жидкой фармацевтической композиции, а твердый фармацевтически активный ингредиент диспергирован в слое оболочки капсулы.
EA201070835A 2008-01-10 2008-12-29 Состав капсулы EA201070835A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2008003634 2008-01-10
PCT/JP2008/073875 WO2009087938A1 (ja) 2008-01-10 2008-12-29 カプセル製剤

Publications (1)

Publication Number Publication Date
EA201070835A1 true EA201070835A1 (ru) 2011-02-28

Family

ID=40853060

Family Applications (3)

Application Number Title Priority Date Filing Date
EA201200830A EA201200830A1 (ru) 2008-01-10 2008-12-29 Состав капсулы
EA201200829A EA201200829A1 (ru) 2008-01-10 2008-12-29 Состав капсулы
EA201070835A EA201070835A1 (ru) 2008-01-10 2008-12-29 Состав капсулы

Family Applications Before (2)

Application Number Title Priority Date Filing Date
EA201200830A EA201200830A1 (ru) 2008-01-10 2008-12-29 Состав капсулы
EA201200829A EA201200829A1 (ru) 2008-01-10 2008-12-29 Состав капсулы

Country Status (21)

Country Link
US (1) US20100285121A1 (ru)
EP (3) EP2455070A1 (ru)
JP (1) JP5421126B2 (ru)
KR (1) KR20100111292A (ru)
CN (3) CN103705487A (ru)
AU (1) AU2008345848B2 (ru)
BR (1) BRPI0822019A2 (ru)
CA (1) CA2711814A1 (ru)
CO (1) CO6290641A2 (ru)
CR (1) CR11625A (ru)
DO (3) DOP2010000214A (ru)
EA (3) EA201200830A1 (ru)
EC (1) ECSP10010395A (ru)
IL (1) IL206791A0 (ru)
MA (1) MA32027B1 (ru)
MX (1) MX2010007609A (ru)
MY (1) MY157189A (ru)
NZ (3) NZ600720A (ru)
UA (3) UA100403C2 (ru)
WO (1) WO2009087938A1 (ru)
ZA (1) ZA201004793B (ru)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5924834B2 (ja) 2008-09-02 2016-05-25 アマリン ファーマシューティカルズ アイルランド リミテッド エイコサペンタエン酸およびニコチン酸を含む製薬組成物ならびにこの製薬組成物を用いる方法
ITFI20080243A1 (it) * 2008-12-15 2010-06-16 Valpharma Sa Formulazioni per la somministrazione orale di acidi grassi omega polienoici in combinazione con statine di origine naturale o semi-sintetica.
WO2010119319A1 (en) 2009-03-09 2010-10-21 Pronova Biopharma Norge As Compositions comprising a fatty acid oil mixture and a free fatty acid, and methods and uses thereof
US20120100208A1 (en) 2009-04-29 2012-04-26 Amarin Pharma, Inc. Stable pharmaceutical composition and methods of using same
MY198422A (en) 2009-04-29 2023-08-29 Amarin Pharmaceuticals Ie Ltd Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same
KR20120016677A (ko) 2009-06-15 2012-02-24 아마린 파마, 인크. 병용 스타틴 요법을 받는 대상체에서 ｌｄｌ－ｃ 수준을 상승시키지 않으면서 트리글리세리드를 저하시키기 위한 조성물 및 방법
NZ599061A (en) 2009-09-23 2014-05-30 Amarin Pharmaceuticals Ie Ltd Pharmaceutical composition comprising omega-3 fatty acid and hydroxy-derivative of a statin and methods of using same
WO2011048493A1 (en) * 2009-10-23 2011-04-28 Pronova Biopharma Norge As Coated capsules and tablets of a fatty acid oil mixture
ES2364011B1 (es) * 2009-11-20 2013-01-24 Gp Pharm, S.A. Cápsulas de principios activos farmacéuticos y ésteres de ácidos grasos poliinsaturados para el tratamiento de enfermedades cardiovasculares.
CA3065589C (en) 2010-06-03 2022-04-26 Catalent Ontario Limited Multi phase soft gel capsules, apparatus and method thereof
CA2706270C (en) * 2010-06-03 2020-01-07 Accucaps Industries Limited Pharmaceutical formulations of statins and omega-3 fatty acids for encapsulation
JP5829607B2 (ja) * 2010-06-30 2015-12-09 持田製薬株式会社 ω３脂肪酸の配合製剤
NZ611606A (en) 2010-11-29 2015-10-30 Amarin Pharmaceuticals Ie Ltd Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity
US11712429B2 (en) 2010-11-29 2023-08-01 Amarin Pharmaceuticals Ireland Limited Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity
US8715648B2 (en) * 2011-02-16 2014-05-06 Pivotal Therapeutics Inc. Method for treating obesity with anti-obesity formulations and omega 3 fatty acids for the reduction of body weight in cardiovascular disease patients (CVD) and diabetics
KR101310710B1 (ko) * 2011-03-23 2013-09-27 한미약품 주식회사 오메가-3 지방산 에스테르 및 ＨＭＧ-ＣｏＡ 환원효소 억제제를 포함하는 경구용 복합 조성물
JP5876695B2 (ja) * 2011-09-29 2016-03-02 森下仁丹株式会社 シームレスカプセルおよびその製造方法
US20130131170A1 (en) 2011-11-07 2013-05-23 Amarin Pharmaceuticals Ireland Limited Methods of treating hypertriglyceridemia
US11291643B2 (en) 2011-11-07 2022-04-05 Amarin Pharmaceuticals Ireland Limited Methods of treating hypertriglyceridemia
KR101466617B1 (ko) * 2011-11-17 2014-11-28 한미약품 주식회사 오메가-3 지방산 및 HMG-CoA 환원효소 억제제를 포함하는 안정성이 증가된 경구용 복합 제제
ES2685703T3 (es) 2012-01-06 2018-10-10 Omthera Pharmaceuticals Inc. Composiciones enriquecidas en DPA de ácidos grasos omega-3 poliinsaturados en forma de ácido libre
AU2013207368A1 (en) 2012-01-06 2014-07-24 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering levels of high-sensitivity (hs-CRP) in a subject
TW201347754A (zh) 2012-05-07 2013-12-01 Omthera Pharmaceuticals Inc 史他汀及ω－３脂肪酸之組合物
JP5990323B2 (ja) * 2012-05-22 2016-09-14 コンイル ファーマシューティカル カンパニー， リミテッド オメガ−３脂肪酸またはそのアルキルエステル、及びスタチン系薬物を含む多層コーティング形態の経口投与用薬学組成物
MX2015000138A (es) 2012-06-29 2015-09-07 Amarin Pharmaceuticals Ie Ltd Metodos para reducir riesgo de evento cardiovascular en sujeto con terapia con estatina.
CN102824640A (zh) * 2012-08-06 2012-12-19 济南圣泉唐和唐生物科技有限公司 一种胶囊壳及其制备方法
WO2014074552A2 (en) 2012-11-06 2014-05-15 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides without raising ldl-c levels in a subject on concomitant statin therapy
US20140187633A1 (en) 2012-12-31 2014-07-03 Amarin Pharmaceuticals Ireland Limited Methods of treating or preventing nonalcoholic steatohepatitis and/or primary biliary cirrhosis
US9814733B2 (en) 2012-12-31 2017-11-14 A,arin Pharmaceuticals Ireland Limited Compositions comprising EPA and obeticholic acid and methods of use thereof
US9452151B2 (en) 2013-02-06 2016-09-27 Amarin Pharmaceuticals Ireland Limited Methods of reducing apolipoprotein C-III
US9624492B2 (en) 2013-02-13 2017-04-18 Amarin Pharmaceuticals Ireland Limited Compositions comprising eicosapentaenoic acid and mipomersen and methods of use thereof
US9662307B2 (en) 2013-02-19 2017-05-30 The Regents Of The University Of Colorado Compositions comprising eicosapentaenoic acid and a hydroxyl compound and methods of use thereof
WO2014134466A1 (en) * 2013-03-01 2014-09-04 Amarin Pharmaceuticals Ireland Limited. Co-administration of atorvastatin and ethyl eicosapentaenoic acid or a derivative thereof
US9283201B2 (en) 2013-03-14 2016-03-15 Amarin Pharmaceuticals Ireland Limited Compositions and methods for treating or preventing obesity in a subject in need thereof
US20140271841A1 (en) * 2013-03-15 2014-09-18 Amarin Pharmaceuticals Ireland Limited Pharmaceutical composition comprising eicosapentaenoic acid and derivatives thereof and a statin
US10966968B2 (en) 2013-06-06 2021-04-06 Amarin Pharmaceuticals Ireland Limited Co-administration of rosiglitazone and eicosapentaenoic acid or a derivative thereof
US20150065572A1 (en) 2013-09-04 2015-03-05 Amarin Pharmaceuticals Ireland Limited Methods of treating or preventing prostate cancer
US9585859B2 (en) 2013-10-10 2017-03-07 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy
DK3103351T3 (en) * 2014-01-31 2019-01-07 Morishita Jintan Co ORAL ADMINISTRATIVE FOR LIFESTYLE AND LIFESTYLE FOODS CONTAINING THE SAME
US10561631B2 (en) 2014-06-11 2020-02-18 Amarin Pharmaceuticals Ireland Limited Methods of reducing RLP-C
US10172818B2 (en) 2014-06-16 2019-01-08 Amarin Pharmaceuticals Ireland Limited Methods of reducing or preventing oxidation of small dense LDL or membrane polyunsaturated fatty acids
DK3160420T3 (da) * 2014-06-26 2019-05-06 Scherer Technologies Llc R P Fremgangsmåder til fremstilling af indkapslet granulært materiale, fremgangsmåder til tørring af belægningsmaterialer og fluid bed-tørrere
MA41611A (fr) 2015-02-23 2018-01-02 Omthera Pharmaceuticals Inc Préparations en milli-capsules comprenant des acides gras polyinsaturés libres
CN104940654A (zh) * 2015-06-24 2015-09-30 黄红林 一种葛根胶囊
KR101950907B1 (ko) 2016-02-05 2019-02-21 한국유나이티드제약 주식회사 지용성 약물 및 방유성 기제가 코팅된 고형제제를 포함하는 경구용 복합제제
US10406130B2 (en) 2016-03-15 2019-09-10 Amarin Pharmaceuticals Ireland Limited Methods of reducing or preventing oxidation of small dense LDL or membrane polyunsaturated fatty acids
WO2018213663A1 (en) 2017-05-19 2018-11-22 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides in a subject having reduced kidney function
CN107422021B (zh) * 2017-07-14 2019-11-19 北京朗阅科技有限公司 琼脂糖胶囊及其制备方法与应用
US11058661B2 (en) 2018-03-02 2021-07-13 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides in a subject on concomitant statin therapy and having hsCRP levels of at least about 2 mg/L
WO2019197961A1 (en) * 2018-04-09 2019-10-17 Intas Pharmaceuticals Ltd. Pharmaceutical composition of nintedanib esylate
JP7020756B2 (ja) 2018-09-24 2022-02-16 アマリン ファーマシューティカルズ アイルランド リミテッド 対象の心血管イベントのリスクを低減する方法

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5488880A (en) * 1977-10-06 1979-07-14 Eru Emu Asoshieito Yuugen Soft capsule
US4444784A (en) * 1980-08-05 1984-04-24 Merck & Co., Inc. Antihypercholesterolemic compounds
JPS5953410A (ja) * 1982-09-20 1984-03-28 Fujisawa Pharmaceut Co Ltd 新型ソフトカプセル剤
JPS59157018A (ja) * 1983-02-27 1984-09-06 Furointo Sangyo Kk 新規なる被覆含油カプセル剤形
GB8305693D0 (en) * 1983-03-02 1983-04-07 Scherer Ltd R P Pharmaceutical compositions
JPS63238015A (ja) * 1987-03-24 1988-10-04 Morishita Jintan Kk 徐放性カプセル製剤
JPH01186815A (ja) * 1988-01-21 1989-07-26 Tokai Kapuseru Kk 軟カプセル剤およびその製造法
JPH01193216A (ja) * 1988-01-29 1989-08-03 Fuji Kapuseru Kk ソフトカプセル及び球状物
JPS6415A (en) * 1988-03-17 1989-01-05 Freunt Ind Co Ltd Absorption-improving drug preparation
GB8819110D0 (en) * 1988-08-11 1988-09-14 Norsk Hydro As Antihypertensive drug & method for production
FI94339C (fi) * 1989-07-21 1995-08-25 Warner Lambert Co Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
JP3159724B2 (ja) 1991-04-19 2001-04-23 フロイント産業株式会社 シームレスカプセル製造方法および装置
JP3144865B2 (ja) * 1991-12-06 2001-03-12 エーザイ株式会社 軟カプセル剤
JPH0753356A (ja) * 1993-08-16 1995-02-28 Morishita Jintan Kk 酸化され易い油性物質を内容物とするシームレスカプセルおよびその製造方法
JPH0823912A (ja) * 1994-07-19 1996-01-30 Yoshinobu Umeda アシタバ入り食品
US5650232A (en) 1994-10-07 1997-07-22 Warner-Lambert Company Method for making seamless capsules
US5641512A (en) * 1995-03-29 1997-06-24 The Procter & Gamble Company Soft gelatin capsule compositions
WO1997010224A1 (en) 1995-09-13 1997-03-20 Takeda Chemical Industries, Ltd. Benzoxazepine compounds, their production and use as lipid lowering agents
GB9706149D0 (en) * 1997-03-25 1997-05-14 Scherer Corp R P Comestible capsules having flavoured coatings
KR100569319B1 (ko) * 1997-10-30 2006-04-07 모리시타 진탄 가부시키가이샤 불포화 지방산 또는 이들의 유도체를 내용물로 하는 캡슐제제 및 그의 제조방법
GB9916536D0 (en) * 1999-07-14 1999-09-15 Scarista Limited Nutritional or pharmaceutical compositions
AR035016A1 (es) 1999-08-25 2004-04-14 Takeda Chemical Industries Ltd Composicion de azol promotor de produccion/secrecion de neurotrofina, compuesto prodroga del mismo, composicion farmaceutica que lo comprende y uso del mismo para preparar esta ultima.
PT1285651E (pt) 2000-04-28 2010-10-21 Takeda Pharmaceutical Antagonistas da hormona concentradora da melanina
US7229986B2 (en) 2000-05-16 2007-06-12 Takeda Pharmaceutical Company Ltd. Melanin-concentrating hormone antagonist
GB0011838D0 (en) 2000-05-17 2000-07-05 Astrazeneca Ab Chemical compounds
JP5105705B2 (ja) * 2002-05-09 2012-12-26 中外製薬株式会社 光安定化軟カプセル剤
KR100490279B1 (ko) * 2002-07-18 2005-05-17 주식회사 서흥캅셀 구취제거 및 구강 청량 효과를 지닌 젤라틴 연질캅셀제
WO2004112777A1 (ja) * 2003-06-20 2004-12-29 Mochida Pharmaceutical Co., Ltd. 下肢静脈瘤予防・治療用組成物
JP2005046054A (ja) * 2003-07-29 2005-02-24 Nippon Kayaku Co Ltd ダイエット食品及びダイエット用製剤
DE102004019916A1 (de) * 2004-04-21 2005-11-17 Grünenthal GmbH Gegen Missbrauch gesichertes wirkstoffhaltiges Pflaster
EP1757275A1 (en) * 2004-04-21 2007-02-28 Kyowa Hakko Kogyo Co., Ltd. Seamless capsule containing water-soluble active ingredient
ES2255426B1 (es) * 2004-10-19 2007-08-16 Gp Pharm, S.A. Formulacion farmaceutica que comprende microcapsulas de estatinas suspendidas en ester alquilicos de acidos grasos poliinsaturados (pufa).
CA2593768C (en) * 2005-01-04 2014-02-18 Mochida Pharmaceutical Co., Ltd. Use of .omega.3 unsaturated fatty acids for relieving lipotoxicity
CN101212953A (zh) * 2005-03-29 2008-07-02 麦克内尔-Ppc股份有限公司 具有疏水介质中的亲水药物的组合物
AR054368A1 (es) * 2005-06-01 2007-06-20 Takeda Pharmaceutical Metodo para tratar hiperlipidemia
JP4327872B2 (ja) 2005-10-07 2009-09-09 トヨタ自動車株式会社 複数枚の回路基板を固定する固定部材とそれを利用したモジュール
WO2007091338A1 (ja) * 2006-02-07 2007-08-16 Mochida Pharmaceutical Co., Ltd. 脳卒中再発予防用組成物
JP4005104B2 (ja) * 2006-02-07 2007-11-07 持田製薬株式会社 脳卒中再発予防用組成物
JP5628480B2 (ja) * 2006-03-09 2014-11-19 グラクソスミスクライン エルエルシー 医薬成分を含有するコーティングカプセル
US8784886B2 (en) * 2006-03-09 2014-07-22 GlaxoSmithKline, LLC Coating capsules with active pharmaceutical ingredients
CA2655615A1 (en) * 2006-06-26 2008-12-17 Valpharma S.A. A pharmaceutical composition for the oral administration of omega polyenoic fatty acids and one or more active principles incompatible therewith, and a process for its preparation
WO2008088030A1 (ja) * 2007-01-17 2008-07-24 Mochida Pharmaceutical Co., Ltd. 血栓もしくは塞栓に関連する疾患の予防又は治療用組成物
CN102552213A (zh) * 2007-06-29 2012-07-11 武田药品工业株式会社 无缝胶囊

Also Published As

Publication number Publication date
UA102478C2 (en) 2013-07-10
CR11625A (es) 2010-09-29
EP2455070A1 (en) 2012-05-23
EP2229939A4 (en) 2011-04-27
JP5421126B2 (ja) 2014-02-19
JPWO2009087938A1 (ja) 2011-05-26
NZ587019A (en) 2012-07-27
EP2455071A1 (en) 2012-05-23
CN103705486A (zh) 2014-04-09
US20100285121A1 (en) 2010-11-11
UA102477C2 (en) 2013-07-10
MY157189A (en) 2016-05-13
EA201200829A1 (ru) 2012-11-30
BRPI0822019A2 (pt) 2015-07-21
CO6290641A2 (es) 2011-06-20
AU2008345848B2 (en) 2014-05-15
KR20100111292A (ko) 2010-10-14
NZ600720A (en) 2012-12-21
CN101969932A (zh) 2011-02-09
EA201200830A1 (ru) 2012-11-30
DOP2010000214A (es) 2010-07-31
NZ600721A (en) 2013-03-28
CN103705487A (zh) 2014-04-09
ECSP10010395A (es) 2010-09-30
UA100403C2 (en) 2012-12-25
ZA201004793B (en) 2011-09-28
EP2229939A1 (en) 2010-09-22
WO2009087938A1 (ja) 2009-07-16
AU2008345848A1 (en) 2009-07-16
DOP2013000087A (es) 2014-01-31
CA2711814A1 (en) 2009-07-16
MA32027B1 (fr) 2011-01-03
MX2010007609A (es) 2010-08-04
DOP2013000085A (es) 2013-06-15
IL206791A0 (en) 2010-12-30

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