EA201100616A1 - Новые формы применения цинеола - Google Patents

Новые формы применения цинеола

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Publication number
EA201100616A1
EA201100616A1 EA201100616A EA201100616A EA201100616A1 EA 201100616 A1 EA201100616 A1 EA 201100616A1 EA 201100616 A EA201100616 A EA 201100616A EA 201100616 A EA201100616 A EA 201100616A EA 201100616 A1 EA201100616 A1 EA 201100616A1
Authority
EA
Eurasian Patent Office
Prior art keywords
capsule
zineol
application
new forms
cineole
Prior art date
Application number
EA201100616A
Other languages
English (en)
Other versions
EA022173B1 (ru
Inventor
Харальд Греве
Вальтер Духач
Original Assignee
Мария Клементине Мартин Клостерфрау Фертрибсгезельшафт Мбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Мария Клементине Мартин Клостерфрау Фертрибсгезельшафт Мбх filed Critical Мария Клементине Мартин Клостерфрау Фертрибсгезельшафт Мбх
Publication of EA201100616A1 publication Critical patent/EA201100616A1/ru
Publication of EA022173B1 publication Critical patent/EA022173B1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833—Encapsulating processes; Filling of capsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Otolaryngology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Изобретение относится к содержащей цинеол форме применения для перорального введения в виде капсулы, причем содержащая цинеол форма применения сформирована в виде системы капсула-в-капсуле, причем система капсула-в-капсуле имеет внешнюю капсулу (наружная капсула) с внешней капсульной оболочкой и множество находящихся во внешней капсуле внутренних капсул (внутренние капсулы), причем внутренние капсулы полностью окружены капсульной оболочкой внешней капсулы и внутренние капсулы сформированы как микрокапсулы, которые соответственно содержат действующее вещество 1,8-цинеол. Далее настоящее изобретение относится к получению и применению этой содержащей цинеол формы применения.
EA201100616A 2010-05-12 2011-05-10 Лекарственная форма, содержащая цинеол, способ ее получения и применение EA022173B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102010020425 2010-05-12
DE102010022174A DE102010022174A1 (de) 2010-05-12 2010-05-21 Neue Darreichungsformen für Cineol

Publications (2)

Publication Number Publication Date
EA201100616A1 true EA201100616A1 (ru) 2012-02-28
EA022173B1 EA022173B1 (ru) 2015-11-30

Family

ID=44263270

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201100616A EA022173B1 (ru) 2010-05-12 2011-05-10 Лекарственная форма, содержащая цинеол, способ ее получения и применение

Country Status (15)

Country Link
US (1) US20160000722A1 (ru)
EP (1) EP2386296B1 (ru)
BR (1) BR112012028868A2 (ru)
CA (1) CA2798068C (ru)
DE (1) DE102010022174A1 (ru)
EA (1) EA022173B1 (ru)
GE (1) GEP20156409B (ru)
HR (1) HRP20150230T1 (ru)
HU (1) HUE024521T2 (ru)
MX (1) MX2012013056A (ru)
PL (1) PL2386296T3 (ru)
RS (1) RS53881B1 (ru)
SI (1) SI2386296T1 (ru)
WO (1) WO2011141108A2 (ru)
ZA (1) ZA201208268B (ru)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102014218857B4 (de) * 2014-09-19 2018-05-03 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Formaldehyd-freies Polymer auf der Basis von Aminoharz für die Mikroverkapselung, Verfahren zu dessen Herstellung sowie dieses umfassendes geformtes Polymererzeugnis
CN109432042B (zh) * 2018-12-24 2022-04-22 石药集团恩必普药业有限公司 一种软胶囊囊壳及其制备方法
CN115518061A (zh) * 2022-10-09 2022-12-27 深圳弘汇生物医药有限公司 桉叶油醇及其组合物在制备治疗肾炎的药物中的应用
CN115611916B (zh) * 2022-10-09 2024-02-02 深圳弘汇生物医药有限公司 一种治疗IgA肾病的中药提取物和组合物及其医药用途

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FR2539626B2 (fr) * 1983-01-25 1985-06-21 Lafon Labor Nouveau procede de preparation de formes galeniques utiles notamment en therapeutique, dietetique, cosmetique et diagnostic, et formes obtenues selon ce procede
FR2645439B1 (fr) 1989-04-07 1991-06-21 Oreal Procede de preparation de capsules d'alginate(s) particulierement adaptees a un usage cosmetique, appareil pour sa mise en oeuvre et composition cosmetique contenant lesdites capsules
JPH02268205A (ja) 1989-04-08 1990-11-01 Yoshida Dental Mfg Co Ltd 医科・歯科用自動椅子の移動位置検出装置
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CA2140660A1 (en) * 1993-06-13 1994-12-22 Uwe R. Juergens Use of terpene compounds for reduced release of arachidonic acid and of inflammation mediators
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FR2762994B1 (fr) * 1997-05-12 2000-02-11 Jacques Vernin Composition a base d'extraits vegetaux et d'huiles essentielles, utilisable en therapeutique, en cosmetique et en dietetique
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KR101538295B1 (ko) * 2006-12-28 2015-07-22 다우 코닝 코포레이션 다핵성 미세캡슐
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EA022312B1 (ru) * 2008-09-04 2015-12-30 Мария Клементине Мартин Клостерфрау Фертрибсгезелльшафт Мбх Монотерпены для лечения заболеваний дыхательных путей, в частности бронхолегочных заболеваний

Also Published As

Publication number Publication date
PL2386296T3 (pl) 2015-06-30
WO2011141108A2 (de) 2011-11-17
ZA201208268B (en) 2013-07-31
EP2386296A2 (de) 2011-11-16
US20160000722A1 (en) 2016-01-07
CA2798068C (en) 2014-11-25
CA2798068A1 (en) 2011-11-17
GEP20156409B (en) 2015-12-10
HRP20150230T1 (en) 2015-06-05
HUE024521T2 (hu) 2016-01-28
RS53881B1 (en) 2015-08-31
DE102010022174A1 (de) 2011-11-17
EP2386296A3 (de) 2012-05-30
MX2012013056A (es) 2013-03-05
EA022173B1 (ru) 2015-11-30
EP2386296B1 (de) 2014-12-24
SI2386296T1 (sl) 2015-04-30
WO2011141108A3 (de) 2012-06-28
BR112012028868A2 (pt) 2016-07-26

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