EA201300388A1 - Соединения замещенного бензамида - Google Patents

Соединения замещенного бензамида

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Publication number
EA201300388A1
EA201300388A1 EA201300388A EA201300388A EA201300388A1 EA 201300388 A1 EA201300388 A1 EA 201300388A1 EA 201300388 A EA201300388 A EA 201300388A EA 201300388 A EA201300388 A EA 201300388A EA 201300388 A1 EA201300388 A1 EA 201300388A1
Authority
EA
Eurasian Patent Office
Prior art keywords
compounds
substituted benzamide
substituted
preparation
medicines
Prior art date
Application number
EA201300388A
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English (en)
Inventor
Мелани Райх
Штефан Шунк
Рут Йошток
Жан Де Ври
Криста Кнайп
Тино Германн
Михаэль Энгельс
Original Assignee
Грюненталь Гмбх
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Filing date
Publication date
Application filed by Грюненталь Гмбх filed Critical Грюненталь Гмбх
Publication of EA201300388A1 publication Critical patent/EA201300388A1/ru

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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
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    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
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    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
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Abstract

Изобретение относится к соединениям замещенного бензамида, к способу их получения, к лекарственным средствам, содержащим эти соединения, и к применению соединений замещенного бензамида для приготовления лекарственных средств.
EA201300388A 2010-09-22 2011-09-21 Соединения замещенного бензамида EA201300388A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10010200 2010-09-22
PCT/EP2011/004732 WO2012038081A1 (de) 2010-09-22 2011-09-21 Substituierte benzamid-verbindungen

Publications (1)

Publication Number Publication Date
EA201300388A1 true EA201300388A1 (ru) 2014-01-30

Family

ID=43770597

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201300388A EA201300388A1 (ru) 2010-09-22 2011-09-21 Соединения замещенного бензамида

Country Status (18)

Country Link
US (1) US8680159B2 (ru)
EP (1) EP2619178A1 (ru)
JP (1) JP2013540750A (ru)
KR (1) KR20140000682A (ru)
CN (1) CN103097354A (ru)
AR (1) AR083167A1 (ru)
AU (1) AU2011304666A1 (ru)
BR (1) BR112013008667A2 (ru)
CA (1) CA2811796A1 (ru)
CL (1) CL2013000787A1 (ru)
CO (1) CO6700838A2 (ru)
EA (1) EA201300388A1 (ru)
EC (1) ECSP13012519A (ru)
IL (1) IL225350A0 (ru)
MX (1) MX2013003309A (ru)
PE (1) PE20131350A1 (ru)
TW (1) TW201217312A (ru)
WO (1) WO2012038081A1 (ru)

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WO2014186704A2 (en) * 2013-05-17 2014-11-20 N30 Pharmaceuticals, Inc. Novel compounds for the treatment of cystic fibrosis
WO2015093515A1 (ja) * 2013-12-19 2015-06-25 エーザイ・アール・アンド・ディー・マネジメント株式会社 １－インダンスルファミド誘導体を含む疼痛の治療および／または予防剤
WO2015090224A1 (zh) 2013-12-20 2015-06-25 中国人民解放军军事医学科学院毒物药物研究所 新型哌啶氨甲酰类化合物、制备方法及其用途
MX2017005940A (es) 2014-11-06 2018-01-11 Lysosomal Therapeutics Inc Pyrazolo [1, 5-a] pirimidinas sustituidas y su uso en el tratamiento de trastornos médicos.
ES2958391T3 (es) 2014-11-06 2024-02-08 Bial R&D Invest S A Imidazo[1,5-a]pirimidinas sustituidas y su uso en el tratamiento de trastornos médicos
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JP7046827B2 (ja) 2016-04-06 2022-04-04 リソソーマル・セラピューティクス・インコーポレイテッド イミダゾ［１，５－ａ］ピリミジニルカルボキサミド化合物および医学的障害の処置におけるその使用
JP7038063B2 (ja) 2016-04-06 2022-03-17 リソソーマル・セラピューティクス・インコーポレイテッド ピラゾロ［１，５－ａ］ピリミジニルカルボキサミド化合物および医学的障害の処置におけるその使用
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