EA201000195A1 - Вирусоподобные частицы вируса гриппа, включающие гемагглютинин, продуцированный в растении - Google Patents

Вирусоподобные частицы вируса гриппа, включающие гемагглютинин, продуцированный в растении

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Publication number
EA201000195A1
EA201000195A1 EA201000195A EA201000195A EA201000195A1 EA 201000195 A1 EA201000195 A1 EA 201000195A1 EA 201000195 A EA201000195 A EA 201000195A EA 201000195 A EA201000195 A EA 201000195A EA 201000195 A1 EA201000195 A1 EA 201000195A1
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EA
Eurasian Patent Office
Prior art keywords
virus
influenza virus
plants
particles
produced
Prior art date
Application number
EA201000195A
Other languages
English (en)
Other versions
EA018206B1 (ru
Inventor
Марк-Андре Д'Ау
Манон КУТЮР
Фредерик Орс
Сонья Трепанье
Пьер-Оливье Лавуа
Мишель Даргис
Луи-Филипп ВЕЗИНА
Натали ЛАНДРИ
Original Assignee
Медикаго Инк.
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Filing date
Publication date
Application filed by Медикаго Инк. filed Critical Медикаго Инк.
Publication of EA201000195A1 publication Critical patent/EA201000195A1/ru
Publication of EA018206B1 publication Critical patent/EA018206B1/ru

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Abstract

В соответствии с изобретением предлагается способ получения вирусоподобных частиц (ВЧ) в растении или его части. Способ включает введение ГА вируса гриппа в растения и очищение методом эксклюзивной хроматографии по размеру. В изобретении также предлагаются ВЧ, содержащие белок ГА вируса гриппа и растительные липиды. В изобретении также предлагается нуклеиновая кислота, кодирующая ГА вируса гриппа, а также векторы, ВЧ могут использоваться для создания вакцин от гриппа, либо для улучшения существующих вакцин.
EA201000195A 2007-07-13 2008-07-11 Вирусоподобные частицы вируса гриппа, включающие гемагглютинин, продуцированный в растении EA018206B1 (ru)

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US95941407P 2007-07-13 2007-07-13
US99060307P 2007-11-27 2007-11-27
US1327207P 2007-12-12 2007-12-12
CA002615372A CA2615372A1 (en) 2007-07-13 2008-01-21 Influenza virus-like particles (vlps) comprising hemagglutinin
US2277508P 2008-01-22 2008-01-22
PCT/CA2008/001281 WO2009009876A1 (en) 2007-07-13 2008-07-11 Influenza virus-like particles (vlps) comprising hemagglutinin produced within a plant

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EA201000195A1 true EA201000195A1 (ru) 2010-10-29
EA018206B1 EA018206B1 (ru) 2013-06-28

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US20230044454A1 (en) 2023-02-09
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