EA201391160A1 - Молекула нуклеиновой кислоты, кодирующей коровый белок вируса гепатита в, и вакцина, содержащая указанную молекулу - Google Patents

Молекула нуклеиновой кислоты, кодирующей коровый белок вируса гепатита в, и вакцина, содержащая указанную молекулу

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EA201391160A1
EA201391160A1 EA201391160A EA201391160A EA201391160A1 EA 201391160 A1 EA201391160 A1 EA 201391160A1 EA 201391160 A EA201391160 A EA 201391160A EA 201391160 A EA201391160 A EA 201391160A EA 201391160 A1 EA201391160 A1 EA 201391160A1
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nucleic acid
hepatitis
virus
encoding
molecule
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EA201391160A
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EA032364B1 (ru
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Дэвид Б. Уэйнер
Цзянь Янь
Ниямекие Обенг-Аджей
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Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания
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Publication of EA201391160A1 publication Critical patent/EA201391160A1/ru
Publication of EA032364B1 publication Critical patent/EA032364B1/ru

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    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
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    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
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Abstract

В данной заявке предложены нуклеиновокислотные последовательности, которые кодируют новую консенсусную аминокислотную последовательность корового белка вируса гепатита В (HBV), а также генетические конструкты/векторы и вакцины, которые экспрессируют указанные белковые последовательности. Также в данной заявке предложены способы получения иммунного ответа на HBV с использованием предложенных нуклеиновокислотных последовательностей.
EA201391160A 2011-02-11 2012-02-13 Молекула нуклеиновой кислоты, кодирующая коровый белок вируса гепатита в, и вакцина, содержащая указанную молекулу EA032364B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161442162P 2011-02-11 2011-02-11
PCT/US2012/024905 WO2012109668A1 (en) 2011-02-11 2012-02-13 Nucleic acid molecule encoding hepatitis b virus core protein and vaccine comprising the same

Publications (2)

Publication Number Publication Date
EA201391160A1 true EA201391160A1 (ru) 2013-12-30
EA032364B1 EA032364B1 (ru) 2019-05-31

Family

ID=46638994

Family Applications (3)

Application Number Title Priority Date Filing Date
EA201892795A EA037377B1 (ru) 2011-02-11 2012-02-13 Вакцина для индукции иммунного ответа на hbv
EA201391160A EA032364B1 (ru) 2011-02-11 2012-02-13 Молекула нуклеиновой кислоты, кодирующая коровый белок вируса гепатита в, и вакцина, содержащая указанную молекулу
EA202092990A EA202092990A3 (ru) 2011-02-11 2012-02-13 Молекула нуклеиновой кислоты, кодирующая коровый белок вируса гепатита в, и вакцина, содержащая указанную молекулу

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EA201892795A EA037377B1 (ru) 2011-02-11 2012-02-13 Вакцина для индукции иммунного ответа на hbv

Family Applications After (1)

Application Number Title Priority Date Filing Date
EA202092990A EA202092990A3 (ru) 2011-02-11 2012-02-13 Молекула нуклеиновой кислоты, кодирующая коровый белок вируса гепатита в, и вакцина, содержащая указанную молекулу

Country Status (15)

Country Link
US (3) US9403879B2 (ru)
EP (2) EP2672992B1 (ru)
JP (2) JP6153473B2 (ru)
KR (1) KR101942372B1 (ru)
CN (1) CN103442732B (ru)
AU (1) AU2012214141B2 (ru)
CA (1) CA2827080C (ru)
EA (3) EA037377B1 (ru)
ES (1) ES2806263T3 (ru)
HU (1) HUE049669T2 (ru)
MX (1) MX343830B (ru)
PL (1) PL2672992T3 (ru)
PT (1) PT2672992T (ru)
WO (1) WO2012109668A1 (ru)
ZA (1) ZA201306009B (ru)

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CN103442732B (zh) 2017-04-12
EA201892795A1 (ru) 2019-05-31
US20190151443A1 (en) 2019-05-23
AU2012214141A1 (en) 2013-09-05
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JP6153473B2 (ja) 2017-06-28
KR101942372B1 (ko) 2019-04-12
US20140023613A1 (en) 2014-01-23
MX343830B (es) 2016-11-24
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