EA201170965A1 - Усовершенствованные вакцины вируса человеческой папилломы и способы их использования - Google Patents

Усовершенствованные вакцины вируса человеческой папилломы и способы их использования

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Publication number
EA201170965A1
EA201170965A1 EA201170965A EA201170965A EA201170965A1 EA 201170965 A1 EA201170965 A1 EA 201170965A1 EA 201170965 A EA201170965 A EA 201170965A EA 201170965 A EA201170965 A EA 201170965A EA 201170965 A1 EA201170965 A1 EA 201170965A1
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Eurasian Patent Office
Prior art keywords
methods
papilloma virus
human papilloma
virus vaccines
improved human
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EA201170965A
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English (en)
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EA023892B1 (ru
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Дэвид Б. Вейнер
Цзянь Янь
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Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания
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Publication of EA201170965A1 publication Critical patent/EA201170965A1/ru
Publication of EA023892B1 publication Critical patent/EA023892B1/ru

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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
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    • A61P31/12—Antivirals
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
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    • C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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Abstract

Раскрыты усовершенствованные иммуногены против ВПЧ и молекулы нуклеиновых кислот, которые их кодируют. Описанные иммуногены включают те, которые имеются у консенсусных ВПЧ 18 Е6 и Е7. Раскрыты фармацевтическая композиция, рекомбинантные вакцины и живые ослабленные вакцины, а также способы вызова иммунного ответа против ВПЧ у индивидуума.
EA201170965A 2009-01-23 2010-01-22 Иммуногенные белки вируса человеческой папилломы и способы их применения EA023892B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14694209P 2009-01-23 2009-01-23
US12/691,588 US8389706B2 (en) 2009-01-23 2010-01-21 Vaccines for human papilloma virus and methods for using the same
PCT/US2010/021869 WO2010085697A1 (en) 2009-01-23 2010-01-22 Improved vaccines for human papilloma virus and methods for using the same

Publications (2)

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EA201170965A1 true EA201170965A1 (ru) 2012-01-30
EA023892B1 EA023892B1 (ru) 2016-07-29

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EA201170965A EA023892B1 (ru) 2009-01-23 2010-01-22 Иммуногенные белки вируса человеческой папилломы и способы их применения

Country Status (14)

Country Link
US (1) US8389706B2 (ru)
EP (1) EP2393496B1 (ru)
JP (2) JP5996191B2 (ru)
KR (1) KR101652764B1 (ru)
CN (2) CN102292089A (ru)
AU (1) AU2010206611B2 (ru)
CA (2) CA2653478A1 (ru)
EA (1) EA023892B1 (ru)
ES (1) ES2592204T3 (ru)
HK (1) HK1245334A1 (ru)
MX (1) MX2011007692A (ru)
PL (1) PL2393496T3 (ru)
PT (1) PT2393496T (ru)
WO (1) WO2010085697A1 (ru)

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JP2015514132A (ja) 2012-04-10 2015-05-18 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア ヒト呼吸器合胞体ウイルスコンセンサス抗原、核酸構築物、およびそれらから作製されるワクチン、ならびにその使用方法
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CA2749120C (en) 2019-09-17
JP2015192673A (ja) 2015-11-05
MX2011007692A (es) 2011-08-12
EP2393496B1 (en) 2016-08-03
WO2010085697A1 (en) 2010-07-29
AU2010206611A1 (en) 2011-07-21
AU2010206611B2 (en) 2015-09-17
US8389706B2 (en) 2013-03-05
KR20110106901A (ko) 2011-09-29
EA023892B1 (ru) 2016-07-29
EP2393496A4 (en) 2012-08-29
EP2393496A1 (en) 2011-12-14
US20100189730A1 (en) 2010-07-29
KR101652764B1 (ko) 2016-08-31
JP5996191B2 (ja) 2016-09-21
PT2393496T (pt) 2016-11-10
CA2749120A1 (en) 2010-07-29
CN102292089A (zh) 2011-12-21
CA2653478A1 (en) 2010-07-23
HK1245334A1 (zh) 2018-08-24
CN107267530A (zh) 2017-10-20
JP2012515557A (ja) 2012-07-12
PL2393496T3 (pl) 2017-02-28
ES2592204T3 (es) 2016-11-28

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