EA201591688A1 - Усовершенствованные вакцины против вируса папилломы человека и способы их применения - Google Patents

Усовершенствованные вакцины против вируса папилломы человека и способы их применения

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EA201591688A1
EA201591688A1 EA201591688A EA201591688A EA201591688A1 EA 201591688 A1 EA201591688 A1 EA 201591688A1 EA 201591688 A EA201591688 A EA 201591688A EA 201591688 A EA201591688 A EA 201591688A EA 201591688 A1 EA201591688 A1 EA 201591688A1
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hpv
methods
disclosed
application
against human
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EA201591688A
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English (en)
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EA034056B1 (ru
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Дэвид Уэйнер
Цзянь Янь
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Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания
Иновио Фармасьютикалз, Инк.
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Publication of EA201591688A1 publication Critical patent/EA201591688A1/ru
Publication of EA034056B1 publication Critical patent/EA034056B1/ru

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Abstract

Раскрыты усовершенствованные анти-ВПЧ иммуногены и молекулы нуклеиновой кислоты, которые их кодируют. Раскрытые иммуногены включают содержащие консенсус ВПЧ 6 Е6Е7, ВПЧ 11 Е6Е7, ВПЧ 16 Е6Е7, ВПЧ 18 Е6Е7, ВПЧ 31 Е6Е7, ВПЧ 33 Е6Е7, ВПЧ 39 Е6Е7, ВПЧ 45 Е6Е7, ВПЧ 52 Е6Е7 и ВПЧ 58 Е6Е7. Раскрыты фармацевтическая композиция, рекомбинантные вакцины, содержащие ДНК плазмиду и живые аттенуированные вакцины, а также раскрыты способы стимуляции иммунного ответа у индивидуума против ВПЧ.
EA201591688A 2013-03-12 2014-03-12 Усовершенствованные вакцины против вируса папилломы человека и способы их применения EA034056B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361777198P 2013-03-12 2013-03-12
PCT/US2014/025106 WO2014165291A1 (en) 2013-03-12 2014-03-12 Improved vaccines for human papilloma virus and methods for using the same

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EA201591688A1 true EA201591688A1 (ru) 2016-01-29
EA034056B1 EA034056B1 (ru) 2019-12-23

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EA201591688A EA034056B1 (ru) 2013-03-12 2014-03-12 Усовершенствованные вакцины против вируса папилломы человека и способы их применения

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US (5) US10232030B2 (ru)
EP (2) EP2968527A4 (ru)
JP (1) JP6517779B2 (ru)
KR (2) KR20150130438A (ru)
CN (2) CN114181961A (ru)
AU (2) AU2014248535B2 (ru)
BR (1) BR112015021974A2 (ru)
CA (1) CA2898522A1 (ru)
EA (2) EA201992282A1 (ru)
HK (1) HK1220905A1 (ru)
MX (2) MX2015011484A (ru)
WO (1) WO2014165291A1 (ru)
ZA (1) ZA201506879B (ru)

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