ES2070997T3 - Virus de herpes recombinante de pavos y vacunas vector vivas derivadas de los mismos. - Google Patents
Virus de herpes recombinante de pavos y vacunas vector vivas derivadas de los mismos.Info
- Publication number
- ES2070997T3 ES2070997T3 ES90203076T ES90203076T ES2070997T3 ES 2070997 T3 ES2070997 T3 ES 2070997T3 ES 90203076 T ES90203076 T ES 90203076T ES 90203076 T ES90203076 T ES 90203076T ES 2070997 T3 ES2070997 T3 ES 2070997T3
- Authority
- ES
- Spain
- Prior art keywords
- turkeys
- herpes viruses
- recombinant herpes
- vector vaccines
- vaccines derived
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- XQFRJNBWHJMXHO-RRKCRQDMSA-N IDUR Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C(I)=C1 XQFRJNBWHJMXHO-RRKCRQDMSA-N 0.000 title abstract 2
- 241000700605 Viruses Species 0.000 title abstract 2
- 229940126580 vector vaccine Drugs 0.000 title abstract 2
- 241000286209 Phasianidae Species 0.000 title 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000037431 insertion Effects 0.000 abstract 1
- 238000003780 insertion Methods 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/04—Inactivation or attenuation; Producing viral sub-units
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
- C12N2710/16322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
- C12N2710/16341—Use of virus, viral particle or viral elements as a vector
- C12N2710/16343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/816—Viral vaccine for avian species, e.g. poultry or other birds
Abstract
ESTA INVENCION SE REFIERE A UN VIRUS RECOMBINANTE DEL HERPES DE LOS PAVOS (HVT) QUE CONTIENE UN GEN HETEROLOGO INCORPORADO EN UNA REGION DE INSERCION DEL GENOMA DE HVT. LA INVENCION SE REFIERE TAMBIEN A UNA VACUNA DE VECTOR QUE COMPRENDE UN HVT RECOMBINANTE QUE EXPRESA UN POLIPEPTIDO ANTIGENICO HETEROLOGO E INDUCE UNA ADECUADA RESPUESTA INMUNOLOGICA SOBRE LA INFECCION DE UN ANIMAL RECEPTOR ADECUADO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP89203071 | 1989-12-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2070997T3 true ES2070997T3 (es) | 1995-06-16 |
Family
ID=8202517
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90203076T Expired - Lifetime ES2070997T3 (es) | 1989-12-04 | 1990-11-21 | Virus de herpes recombinante de pavos y vacunas vector vivas derivadas de los mismos. |
Country Status (13)
Country | Link |
---|---|
US (2) | US5187087A (es) |
EP (1) | EP0431668B1 (es) |
JP (1) | JP3194751B2 (es) |
KR (1) | KR0179994B1 (es) |
CN (1) | CN1056878C (es) |
AU (1) | AU633663B2 (es) |
BR (1) | BR1100637A (es) |
CA (1) | CA2031164C (es) |
DE (1) | DE69016956T2 (es) |
ES (1) | ES2070997T3 (es) |
HU (1) | HU214904B (es) |
NZ (1) | NZ236294A (es) |
ZA (1) | ZA909570B (es) |
Families Citing this family (85)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5928648A (en) * | 1985-09-06 | 1999-07-27 | Syntro Corporation | Recombinant herpesvirus of turkeys and uses thereof |
US5961982A (en) * | 1985-09-06 | 1999-10-05 | Syntro Corporation | Recombinant herpesvirus of turkeys and uses thereof |
US5965138A (en) * | 1985-09-06 | 1999-10-12 | Syntro Corporation | Recombinant chimeric virus and uses thereof |
WO1990002802A2 (en) * | 1988-09-13 | 1990-03-22 | Institute For Animal Health Limited | Viral nucleotide sequences |
FR2693472B1 (fr) * | 1992-06-26 | 1994-12-23 | Rhone Merieux | Mutants du virus de la rhinotrachéite infectieuse bovine, délétés dans l'un des gènes des glycoprotéines mineures, vaccins préparés à partir de ces souches, méthodes de production et méthodes d'utilisation. |
FR2659349B1 (fr) * | 1990-03-12 | 1993-12-24 | Rhone Merieux | Virus herpes recombinants notamment pour la realisation de vaccins, leur procede de preparation, les plasmides realises au cours de ce procede et les vaccins obtenus. |
EP0473210B1 (en) * | 1990-07-30 | 1994-04-13 | Akzo Nobel N.V. | Recombinant Marek's disease virus |
FR2666589B1 (fr) * | 1990-09-07 | 1994-08-05 | Rhone Merieux | Nouveaux virus herpes recombinants, vaccin a base de ces recombinants, leur procede de preparation, genes, vecteurs et plasmides utilises dans ce procede. |
ZA918426B (en) * | 1990-10-31 | 1992-12-30 | Akzo Nv | Chicken anemia virus vaccine and diagnostic |
DE4110962A1 (de) * | 1991-04-05 | 1992-10-08 | Bayer Ag | Equine herpesviren (ehv), die fremd-dna enthalten, verfahren zu ihrer herstellung und ihre verwendung in impfstoffen |
AU657144B2 (en) * | 1991-07-09 | 1995-03-02 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Recombinant Marek's disease virus, process for preparing the same and vaccine containing the same |
US5853733A (en) * | 1993-02-26 | 1998-12-29 | Syntro Corporation | Recombinant herpesvirus of turkeys and uses thereof |
US6913751B2 (en) | 1992-06-12 | 2005-07-05 | Schering-Plough Veterinary Corporation | Recombinant avian herpesvirus useful in vaccine production |
ES2187508T3 (es) | 1992-07-30 | 2003-06-16 | Akzo Nobel Nv | Vacunas vectores de herpes virus felino recombinado. |
US5403582A (en) * | 1993-01-21 | 1995-04-04 | Nippon Zeon Co., Ltd. | Vaccine comprising fowlpox virus recombinants expressing the envelope glycoprotein of an avian reticuloendotheliosis retrovirus |
EP0609739A1 (en) * | 1993-02-02 | 1994-08-10 | American Cyanamid Company | Method of reversing immunosuppression in vaccines |
US6984728B2 (en) | 1993-09-24 | 2006-01-10 | Schering Corporation | Recombinant infectious laryngotracheitis virus and uses thereof |
EP0745127A4 (en) * | 1994-01-11 | 1999-10-20 | Cornell Res Foundation Inc | CONTROLLING MARE'S DISEASE BY PREVENTING LATENCY AND DEVELOPING TUMOR CELLS |
EP0750670A1 (en) * | 1994-02-07 | 1997-01-02 | Cornell Research Foundation, Inc. | Compositions useful in controlling marek's disease |
FR2719056B1 (fr) * | 1994-04-20 | 1996-09-06 | Rhone Merieux | Herpesvirus transformés pour exprimer gD in vitro. |
US5833980A (en) * | 1995-10-27 | 1998-11-10 | Board Of Trustess Operating Michigan State University | Sustainable cell line for the production of the Marek's disease vaccines |
US6048535A (en) * | 1997-06-12 | 2000-04-11 | Regents Of The University Of Minnesota | Multivalent in ovo avian vaccine |
US6632664B1 (en) * | 1997-10-03 | 2003-10-14 | Nippon Zeon Co., Ltd. | Avian infectious herpesvirus recombinants and recombinant vaccines prepared with the use of the same |
US8119395B1 (en) | 1998-02-27 | 2012-02-21 | The Trustees Of The University Of Pennsylvania | Vaccines, immunotherapeutics and methods for using the same |
CN1120238C (zh) * | 1998-05-04 | 2003-09-03 | 本元正阳基因技术股份有限公司 | 以粘粒为基础构建重组单纯疱疹病毒及其用途 |
EP1038952A3 (en) | 1998-12-09 | 2001-06-27 | Pfizer Products Inc. | Processes for preparation of Marek's Disease Virus using continuous avian cell lines |
MXPA01008883A (es) | 1999-03-03 | 2003-07-21 | Univ Pennsylvania | Vacunas y composiciones para terapia de genes y metodos para fabricar y usar los mismos. |
CA2369747A1 (en) | 1999-04-30 | 2000-11-09 | The Trustees Of The University Of Pennsylvania | Mutant human cd80 and compositions for and methods of making and using the same |
WO2001005988A1 (en) * | 1999-07-16 | 2001-01-25 | Merial Select, Inc | Live recombinant vaccine against avian leukosis virus using a marek's disease virus (mdv) virus as vector |
KR100815888B1 (ko) * | 2000-07-14 | 2008-03-21 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | Hiv 보조 단백질을 암호화하는 dna 백신 |
AU2002211524B2 (en) * | 2000-10-04 | 2007-03-22 | The Trustees Of The University Of Pennsylvania | Highly expressible genes |
AR031405A1 (es) * | 2000-11-21 | 2003-09-24 | Wyeth Corp | Metodos y vacunas para conferir proteccion in ovo contra la rinotraqueitis del pavo |
US7314715B2 (en) | 2001-06-14 | 2008-01-01 | Schering-Plough Animal Health Corporation | Recombinant avian herpesvirus useful in vaccine production |
US8008265B2 (en) | 2003-06-13 | 2011-08-30 | The Trustees Of The University Of Pennsylvania | Vaccines, immunotherapeutics and methods for using the same |
NZ570709A (en) | 2003-06-13 | 2010-04-30 | Univ Pennsylvania | Nucleic acid sequences encoding and compositions comprising IgE signal peptide and/or IL-15 and methods for using the same |
US20080274140A1 (en) * | 2004-11-19 | 2008-11-06 | David B Weiner | Vaccines and Methods for Using the Same |
KR101421745B1 (ko) * | 2006-01-13 | 2014-07-22 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | 코돈 최적화된 il―15를 사용하는 백신 및 면역치료제, 및 그의 사용 방법 |
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EA037377B1 (ru) | 2011-02-11 | 2021-03-22 | Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания | Вакцина для индукции иммунного ответа на hbv |
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CN103687625B (zh) | 2011-07-11 | 2017-06-13 | 艾诺奥医药品有限公司 | 交叉保护性沙粒病毒疫苗及其使用方法 |
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HUE041723T2 (hu) * | 2011-10-21 | 2019-05-28 | Intervet Int Bv | Rekombináns nem patogén marek betegség vírus konstruktok, amelyek fertõzõ Laryngotracheitis vírus és Newcastle-betegség vírus antigéneket kódolnak |
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US9114108B2 (en) | 2011-11-30 | 2015-08-25 | Merial, Inc. | Recombinant HVT vectors expressing antigens of avian pathogens and uses thereof |
US9101598B2 (en) | 2011-11-30 | 2015-08-11 | Merial, Inc. | Recombinant Gallid herpesvirus 3 (MDV serotype 2) vectors expressing antigens of avian pathogens and uses thereof |
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US9750795B2 (en) | 2011-12-12 | 2017-09-05 | The Trustees Of The University Of Pennsylvania | Proteins comprising MRSA PBP2a and fragments thereof, nucleic acids encoding the same, and compositions and their use to prevent and treat MRSA infections |
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US10040828B2 (en) | 2012-04-10 | 2018-08-07 | The Trustees Of The University Of Pennsylvania | Human respiratory syncytial virus consensus antigens, nucleic acid constructs and vaccines made therefrom, and methods of using same |
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US9993545B2 (en) | 2013-03-15 | 2018-06-12 | The Trustees Of The University Of Pennsylvania | Foot and mouth disease virus (FMDV) consensus proteins, coding sequences therefor and vaccines made therefrom |
EA034110B1 (ru) | 2013-03-15 | 2019-12-27 | Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания | Противораковые вакцины и способы лечения с их применением |
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AR103245A1 (es) | 2014-12-24 | 2017-04-26 | Intervet Int Bv | Vacuna vectorial basada en hvt (herpes virus de los pavos) frente a nd (enfermedad de newcastle) - ibd (enfermedad de gumboro) mejorada |
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AU628294B2 (en) * | 1987-07-27 | 1992-09-17 | Syntro Corporation | Attenuated herpes viruses, herpes viruses which include foreign dna encoding an amino acid sequence and vaccines containing same |
JP2779447B2 (ja) * | 1988-03-20 | 1998-07-23 | 財団法人阪大微生物病研究会 | 弱毒マレック病ウイルス・ベクターを用いる組換え遺伝子作成法、及び該ウイルスの組換え体 |
-
1990
- 1990-11-21 ES ES90203076T patent/ES2070997T3/es not_active Expired - Lifetime
- 1990-11-21 DE DE69016956T patent/DE69016956T2/de not_active Expired - Lifetime
- 1990-11-21 EP EP90203076A patent/EP0431668B1/en not_active Expired - Lifetime
- 1990-11-28 ZA ZA909570A patent/ZA909570B/xx unknown
- 1990-11-29 CA CA002031164A patent/CA2031164C/en not_active Expired - Lifetime
- 1990-11-30 NZ NZ236294A patent/NZ236294A/en unknown
- 1990-11-30 US US07/621,193 patent/US5187087A/en not_active Expired - Lifetime
- 1990-12-03 HU HU908031A patent/HU214904B/hu unknown
- 1990-12-03 AU AU67698/90A patent/AU633663B2/en not_active Expired
- 1990-12-03 CN CN90110319A patent/CN1056878C/zh not_active Expired - Lifetime
- 1990-12-04 KR KR1019900019817A patent/KR0179994B1/ko not_active IP Right Cessation
- 1990-12-04 JP JP41928690A patent/JP3194751B2/ja not_active Expired - Lifetime
-
1993
- 1993-02-16 US US08/018,489 patent/US5470734A/en not_active Expired - Lifetime
-
1997
- 1997-05-13 BR BR1100637A patent/BR1100637A/pt active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
JP3194751B2 (ja) | 2001-08-06 |
AU6769890A (en) | 1991-06-06 |
EP0431668B1 (en) | 1995-02-15 |
CA2031164A1 (en) | 1991-06-05 |
CN1052896A (zh) | 1991-07-10 |
HU908031D0 (en) | 1991-06-28 |
KR910012233A (ko) | 1991-08-07 |
DE69016956D1 (de) | 1995-03-23 |
CA2031164C (en) | 2001-10-16 |
KR0179994B1 (ko) | 1999-04-01 |
JPH05103667A (ja) | 1993-04-27 |
ZA909570B (en) | 1991-10-30 |
AU633663B2 (en) | 1993-02-04 |
US5187087A (en) | 1993-02-16 |
CN1056878C (zh) | 2000-09-27 |
HUT57264A (en) | 1991-11-28 |
HU214904B (hu) | 1998-07-28 |
EP0431668A1 (en) | 1991-06-12 |
BR1100637A (pt) | 2000-03-21 |
US5470734A (en) | 1995-11-28 |
DE69016956T2 (de) | 1995-07-20 |
NZ236294A (en) | 1992-05-26 |
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