EA201892795A1 - Молекула нуклеиновой кислоты, кодирующая коровый белок вируса гепатита в, и вакцина, содержащая указанную молекулу - Google Patents

Молекула нуклеиновой кислоты, кодирующая коровый белок вируса гепатита в, и вакцина, содержащая указанную молекулу

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EA201892795A1
EA201892795A1 EA201892795A EA201892795A EA201892795A1 EA 201892795 A1 EA201892795 A1 EA 201892795A1 EA 201892795 A EA201892795 A EA 201892795A EA 201892795 A EA201892795 A EA 201892795A EA 201892795 A1 EA201892795 A1 EA 201892795A1
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nucleic acid
hepatitis
virus
molecule
containing specific
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EA201892795A
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EA037377B1 (ru
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Дэвид Б. Уэйнер
Цзянь Янь
Ниямекие Обенг-Аджей
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Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания
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Publication of EA201892795A1 publication Critical patent/EA201892795A1/ru
Publication of EA037377B1 publication Critical patent/EA037377B1/ru

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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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Abstract

В заявке предложены нуклеиновокислотные последовательности, которые кодируют новую консенсусную аминокислотную последовательность корового белка вируса гепатита B (HBV), а также генетические конструкты/векторы и вакцины, которые экспрессируют указанные белковые последовательности. Также в данной заявке предложены способы получения иммунного ответа на HBV с использованием предложенных нуклеиновокислотных последовательностей.
EA201892795A 2011-02-11 2012-02-13 Вакцина для индукции иммунного ответа на hbv EA037377B1 (ru)

Applications Claiming Priority (1)

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US201161442162P 2011-02-11 2011-02-11

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EA201892795A1 true EA201892795A1 (ru) 2019-05-31
EA037377B1 EA037377B1 (ru) 2021-03-22

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EA202092990A EA202092990A3 (ru) 2011-02-11 2012-02-13 Молекула нуклеиновой кислоты, кодирующая коровый белок вируса гепатита в, и вакцина, содержащая указанную молекулу
EA201391160A EA032364B1 (ru) 2011-02-11 2012-02-13 Молекула нуклеиновой кислоты, кодирующая коровый белок вируса гепатита в, и вакцина, содержащая указанную молекулу
EA201892795A EA037377B1 (ru) 2011-02-11 2012-02-13 Вакцина для индукции иммунного ответа на hbv

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EA202092990A EA202092990A3 (ru) 2011-02-11 2012-02-13 Молекула нуклеиновой кислоты, кодирующая коровый белок вируса гепатита в, и вакцина, содержащая указанную молекулу
EA201391160A EA032364B1 (ru) 2011-02-11 2012-02-13 Молекула нуклеиновой кислоты, кодирующая коровый белок вируса гепатита в, и вакцина, содержащая указанную молекулу

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US (3) US9403879B2 (ru)
EP (2) EP2672992B1 (ru)
JP (2) JP6153473B2 (ru)
KR (1) KR101942372B1 (ru)
CN (1) CN103442732B (ru)
AU (1) AU2012214141B2 (ru)
CA (1) CA2827080C (ru)
EA (3) EA202092990A3 (ru)
ES (1) ES2806263T3 (ru)
HU (1) HUE049669T2 (ru)
MX (1) MX343830B (ru)
PL (1) PL2672992T3 (ru)
PT (1) PT2672992T (ru)
WO (1) WO2012109668A1 (ru)
ZA (1) ZA201306009B (ru)

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JP6153473B2 (ja) 2017-06-28
EA202092990A3 (ru) 2021-07-30
MX343830B (es) 2016-11-24
EP2672992B1 (en) 2020-04-08
EA201391160A1 (ru) 2013-12-30
CA2827080A1 (en) 2012-08-16
EP2672992A4 (en) 2015-07-08
PT2672992T (pt) 2020-07-27
US9403879B2 (en) 2016-08-02
ZA201306009B (en) 2015-03-25
WO2012109668A1 (en) 2012-08-16
AU2012214141B2 (en) 2016-01-28
US20140023613A1 (en) 2014-01-23
EA032364B1 (ru) 2019-05-31
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ES2806263T3 (es) 2021-02-17
CN103442732B (zh) 2017-04-12
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EP3760227A1 (en) 2021-01-06
MX2013009274A (es) 2013-09-06
KR20140048853A (ko) 2014-04-24
CN103442732A (zh) 2013-12-11
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US10695421B2 (en) 2020-06-30
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