EA200702116A1 - Фармацевтическая дозированная форма (варианты) с контролируемым высвобождением антигипергликемического средства в комбинации с производным тиазолидиндиона - Google Patents

Фармацевтическая дозированная форма (варианты) с контролируемым высвобождением антигипергликемического средства в комбинации с производным тиазолидиндиона

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Publication number
EA200702116A1
EA200702116A1 EA200702116A EA200702116A EA200702116A1 EA 200702116 A1 EA200702116 A1 EA 200702116A1 EA 200702116 A EA200702116 A EA 200702116A EA 200702116 A EA200702116 A EA 200702116A EA 200702116 A1 EA200702116 A1 EA 200702116A1
Authority
EA
Eurasian Patent Office
Prior art keywords
combination
controlled release
antihyperglycemic
derivative
tiazolidindion
Prior art date
Application number
EA200702116A
Other languages
English (en)
Other versions
EA015244B1 (ru
Inventor
Казухиро Окоти
Авинаш Нанджа
Анкали Лодин
Джек Р. Кардинал
Original Assignee
Уотсон Фармасьютикалс, Инк.
Такеда Фармасьютикал Кампэни, Лимитид
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37073782&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA200702116(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Уотсон Фармасьютикалс, Инк., Такеда Фармасьютикал Кампэни, Лимитид filed Critical Уотсон Фармасьютикалс, Инк.
Publication of EA200702116A1 publication Critical patent/EA200702116A1/ru
Publication of EA015244B1 publication Critical patent/EA015244B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

В данном материале раскрыта и описана фармацевтическая дозированная форма, содержащая компонент с контролируемым высвобождением, включающий антигипергликемический лекарственный препарат в комбинации со вторым компонентом, включающим производное тиазолидиндиона.
EA200702116A 2005-03-30 2006-03-13 Фармацевтическая дозированная форма (варианты) с контролируемым высвобождением метформина в комбинации с гидрохлоридом пиоглитазона EA015244B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/093,742 US9060941B2 (en) 2002-09-20 2005-03-30 Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
PCT/US2006/009082 WO2006107528A1 (en) 2005-03-30 2006-03-13 Novel pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative

Publications (2)

Publication Number Publication Date
EA200702116A1 true EA200702116A1 (ru) 2008-02-28
EA015244B1 EA015244B1 (ru) 2011-06-30

Family

ID=37073782

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200702116A EA015244B1 (ru) 2005-03-30 2006-03-13 Фармацевтическая дозированная форма (варианты) с контролируемым высвобождением метформина в комбинации с гидрохлоридом пиоглитазона

Country Status (25)

Country Link
US (1) US9060941B2 (ru)
EP (1) EP1863445B1 (ru)
JP (2) JP5827781B2 (ru)
KR (1) KR101401412B1 (ru)
CN (1) CN101222912B (ru)
AR (1) AR054238A1 (ru)
AU (1) AU2006232993B2 (ru)
BR (1) BRPI0609550A2 (ru)
CA (1) CA2601501C (ru)
CR (1) CR9355A (ru)
EA (1) EA015244B1 (ru)
ES (1) ES2573321T3 (ru)
GE (1) GEP20104936B (ru)
HK (1) HK1114337A1 (ru)
IL (1) IL186308A (ru)
MA (1) MA29675B1 (ru)
MX (1) MX2007011824A (ru)
NO (1) NO20075427L (ru)
NZ (1) NZ561124A (ru)
PE (1) PE20061389A1 (ru)
SG (1) SG160415A1 (ru)
TW (1) TWI344375B (ru)
UA (1) UA91852C2 (ru)
WO (1) WO2006107528A1 (ru)
ZA (1) ZA200707137B (ru)

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AU2006232993B2 (en) 2012-01-19
NO20075427L (no) 2007-10-25
CR9355A (es) 2008-01-21
BRPI0609550A2 (pt) 2010-04-13
MX2007011824A (es) 2008-02-12
CA2601501C (en) 2013-04-09
EA015244B1 (ru) 2011-06-30
TWI344375B (en) 2011-07-01
PE20061389A1 (es) 2007-01-21
TW200718433A (en) 2007-05-16
SG160415A1 (en) 2010-04-29
MA29675B1 (fr) 2008-08-01
WO2006107528A1 (en) 2006-10-12
US20050226928A1 (en) 2005-10-13
CN101222912B (zh) 2012-10-03
CN101222912A (zh) 2008-07-16
EP1863445A4 (en) 2012-08-01
JP5827781B2 (ja) 2015-12-02
IL186308A (en) 2014-05-28
AU2006232993A1 (en) 2006-10-12
JP2008534589A (ja) 2008-08-28
KR101401412B1 (ko) 2014-06-11
ES2573321T3 (es) 2016-06-07
UA91852C2 (ru) 2010-09-10
EP1863445A1 (en) 2007-12-12
KR20080005359A (ko) 2008-01-11
US9060941B2 (en) 2015-06-23
CA2601501A1 (en) 2006-10-12
ZA200707137B (en) 2014-07-30
EP1863445B1 (en) 2016-05-11
HK1114337A1 (en) 2008-10-31
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JP2013209426A (ja) 2013-10-10
NZ561124A (en) 2010-12-24

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