AR054238A1 - Composicion farmaceutica que contiene una biguanida y un derivado de tiazolidindiona - Google Patents
Composicion farmaceutica que contiene una biguanida y un derivado de tiazolidindionaInfo
- Publication number
- AR054238A1 AR054238A1 AR20060100990A ARP060100990A AR054238A1 AR 054238 A1 AR054238 A1 AR 054238A1 AR 20060100990 A AR20060100990 A AR 20060100990A AR P060100990 A ARP060100990 A AR P060100990A AR 054238 A1 AR054238 A1 AR 054238A1
- Authority
- AR
- Argentina
- Prior art keywords
- dosage form
- derivative
- component
- thiazolidinedione
- tiazolidindiona
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
Forma de dosificacion farmacéutica que comprende un componente de liberacion controlada que comprende una droga antihiperglucémica en combinacion con un segundo componente que comprende un derivado de tiazolidindiona. Reivindicacion 1: Una forma de dosificacion farmacéutica que contiene una primera y una segunda droga activa, caracterizada porque dicha forma de dosificacion comprende: (a) un nucleo de liberacion controlada que comprende una droga antihiperglucémica y al menos un excipiente aceptable para uso farmacéutico; y (b) un derivado de tiazolidindiona de liberacion inmediata que contiene un componente que comprende un derivado de tiazolidindiona y un aglutinante de baja viscosidad soluble en agua donde no menos del 85% de la tiazolidindiona se libera a partir de la forma de dosificacion dentro de los 45 minutos cuando se la evalua de acuerdo con la Farmacopea de los EE.UU. (USP) 26, con el Aparato 1 a 100rpm, 37 degree C y 900 ml de solucion amortiguadora de KCl 0,3 M-HCL, pH 2,0.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/093,742 US9060941B2 (en) | 2002-09-20 | 2005-03-30 | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
AR054238A1 true AR054238A1 (es) | 2007-06-13 |
Family
ID=37073782
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AR20060100990A AR054238A1 (es) | 2005-03-30 | 2006-03-15 | Composicion farmaceutica que contiene una biguanida y un derivado de tiazolidindiona |
Country Status (25)
Country | Link |
---|---|
US (1) | US9060941B2 (es) |
EP (1) | EP1863445B1 (es) |
JP (2) | JP5827781B2 (es) |
KR (1) | KR101401412B1 (es) |
CN (1) | CN101222912B (es) |
AR (1) | AR054238A1 (es) |
AU (1) | AU2006232993B2 (es) |
BR (1) | BRPI0609550A2 (es) |
CA (1) | CA2601501C (es) |
CR (1) | CR9355A (es) |
EA (1) | EA015244B1 (es) |
ES (1) | ES2573321T3 (es) |
GE (1) | GEP20104936B (es) |
HK (1) | HK1114337A1 (es) |
IL (1) | IL186308A (es) |
MA (1) | MA29675B1 (es) |
MX (1) | MX2007011824A (es) |
NO (1) | NO20075427L (es) |
NZ (1) | NZ561124A (es) |
PE (1) | PE20061389A1 (es) |
SG (1) | SG160415A1 (es) |
TW (1) | TWI344375B (es) |
UA (1) | UA91852C2 (es) |
WO (1) | WO2006107528A1 (es) |
ZA (1) | ZA200707137B (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030153607A1 (en) * | 1998-11-12 | 2003-08-14 | Smithkline Beecham P.L.C. | Novel composition and use |
US20040102486A1 (en) * | 1998-11-12 | 2004-05-27 | Smithkline Beecham Corporation | Novel method of treatment |
US8911781B2 (en) | 2002-06-17 | 2014-12-16 | Inventia Healthcare Private Limited | Process of manufacture of novel drug delivery system: multilayer tablet composition of thiazolidinedione and biguanides |
US7785627B2 (en) * | 2002-09-20 | 2010-08-31 | Watson Pharmaceuticals, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
US7588779B2 (en) * | 2004-05-28 | 2009-09-15 | Andrx Labs, Llc | Pharmaceutical formulation containing a biguanide and an angiotensin antagonist |
US20080026054A1 (en) * | 2007-04-27 | 2008-01-31 | Nectid Inc. | Novel anelgesic combination |
US20080031950A1 (en) * | 2007-04-27 | 2008-02-07 | Nectid Inc. | Novel anelgesic combination |
NZ588695A (en) * | 2008-03-21 | 2012-11-30 | Mylan Pharmaceuticals Inc | Extended release forumulation containing a wax and ciprofloxacin |
DE102008059206A1 (de) * | 2008-11-27 | 2010-06-10 | Bayer Schering Pharma Aktiengesellschaft | Pharmazeutische Darreichungsform enthaltend Nifedipin oder Nisoldipin und einen Angiotensin-II Antagonisten und/oder ein Diuretikum |
US20130251795A1 (en) * | 2010-07-30 | 2013-09-26 | Ranbaxy Laboratories Limited | Pharmaceutical compositions containing a biguanide and a low dose antidiabetic agent |
US20120093878A1 (en) * | 2010-07-30 | 2012-04-19 | Ranbaxy Laboratories Limited | Pharmaceutical compositions containing a biguanide and a thiazolidinedione |
CN101912375A (zh) * | 2010-08-26 | 2010-12-15 | 冯岩 | 一种二甲双胍控释片 |
CN102727459A (zh) * | 2011-04-15 | 2012-10-17 | 江苏豪森医药集团有限公司 | 一种具有第一和第二活性药物的制剂 |
EA201490840A1 (ru) | 2011-10-21 | 2014-08-29 | Такеда Фармасьютикал Компани Лимитед | Препарат с замедленным высвобождением |
EP2987489A4 (en) * | 2013-04-19 | 2016-09-07 | Takeda Pharmaceutical | MEDICINAL FORMULATION WITH DELAYED RELEASE |
MA39929A (fr) * | 2014-11-27 | 2016-06-01 | Arven Ilac Sanayi Ve Ticaret As | Comprimé multicouche comprenant de la metformine et du pioglitazone |
CA3107945A1 (en) * | 2018-08-02 | 2020-02-06 | Hospital Sant Joan De Deu | Immediate release formulation of a triple combination of active pharmaceutical ingredients useful in the treatment of polycystic ovary syndrome |
GB202006849D0 (en) | 2020-05-08 | 2020-06-24 | Kancera Ab | New use |
Family Cites Families (102)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3174901A (en) * | 1963-01-31 | 1965-03-23 | Jan Marcel Didier Aron Samuel | Process for the oral treatment of diabetes |
US3621097A (en) * | 1970-03-30 | 1971-11-16 | Jan Marcel Didier Aron Samuel | Method and compositions for treatment of mental illness |
US3960949A (en) * | 1971-04-02 | 1976-06-01 | Schering Aktiengesellschaft | 1,2-Biguanides |
US3845770A (en) * | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
US3916899A (en) * | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
US4080472A (en) * | 1974-03-22 | 1978-03-21 | Societe D'etudes Et D'exploitation De Marques Et Brevets S.E.M.S. | Metformin 2-(p-chlorophenoxy)-2-methylpropionate |
US4034758A (en) * | 1975-09-08 | 1977-07-12 | Alza Corporation | Osmotic therapeutic system for administering medicament |
US4077407A (en) * | 1975-11-24 | 1978-03-07 | Alza Corporation | Osmotic devices having composite walls |
US4058122A (en) * | 1976-02-02 | 1977-11-15 | Alza Corporation | Osmotic system with laminated wall formed of different materials |
US4166800A (en) * | 1977-08-25 | 1979-09-04 | Sandoz, Inc. | Processes for preparation of microspheres |
US4220648A (en) * | 1979-01-22 | 1980-09-02 | The Upjohn Company | Antidiabetic 1,2-dihydro-2-oxo-6-neopentyl-nicotinic acids |
US4389330A (en) * | 1980-10-06 | 1983-06-21 | Stolle Research And Development Corporation | Microencapsulation process |
US4783337A (en) * | 1983-05-11 | 1988-11-08 | Alza Corporation | Osmotic system comprising plurality of members for dispensing drug |
US4968507A (en) * | 1984-06-20 | 1990-11-06 | Merck & Co., Inc. | Controlled porosity osmotic pump |
CA1266827A (en) | 1984-06-20 | 1990-03-20 | Merck & Co., Inc. | Controlled porosity osmotic pump |
AR240698A1 (es) * | 1985-01-19 | 1990-09-28 | Takeda Chemical Industries Ltd | Procedimiento para preparar compuestos de 5-(4-(2-(5-etil-2-piridil)-etoxi)benzil)-2,4-tiazolidindiona y sus sales |
IT1188212B (it) * | 1985-12-20 | 1988-01-07 | Paolo Colombo | Sistema per il rilascio a velocita' controllata di sostanze attive |
GB8618811D0 (en) * | 1986-08-01 | 1986-09-10 | Approved Prescription Services | Sustained release ibuprofen formulation |
CH668187A5 (de) * | 1986-08-07 | 1988-12-15 | Ciba Geigy Ag | Therapeutisches system mit systemischer wirkung. |
FR2611500B1 (fr) | 1987-03-06 | 1990-05-04 | Lipha | Emploi de derives du biguanide dans la preparation de medicaments |
US4891223A (en) * | 1987-09-03 | 1990-01-02 | Air Products And Chemicals, Inc. | Controlled release delivery coating formulation for bioactive substances |
GB8724763D0 (en) * | 1987-10-22 | 1987-11-25 | Aps Research Ltd | Sustained-release formulations |
US4857337A (en) * | 1988-05-24 | 1989-08-15 | American Home Products Corp. (Del) | Enteric coated aspirin tablets |
US5612059A (en) * | 1988-08-30 | 1997-03-18 | Pfizer Inc. | Use of asymmetric membranes in delivery devices |
DD295760A5 (de) * | 1989-01-31 | 1991-11-14 | Martin-Luther-Universitaet Halle Wittenberg,De | Arzneistoffreigabesystem mit kotrollierter wirkstoffreisetzung |
IE69174B1 (en) | 1989-01-31 | 1996-08-07 | Int Pharma Agentur | A system for the controlled release of active agents and a process for its preparation |
US5356913A (en) * | 1990-02-09 | 1994-10-18 | The Upjohn Company | Use of insulin sensitizing agents to treat hypertension |
ES2101866T3 (es) | 1991-08-26 | 1997-07-16 | Upjohn Co | Producto alimentario liquido que contiene acido 3-guanidinopropionico. |
US5200194A (en) * | 1991-12-18 | 1993-04-06 | Alza Corporation | Oral osmotic device |
US5294770A (en) * | 1992-01-14 | 1994-03-15 | Alza Corporation | Laser tablet treatment system with dual access to tablet |
US5376771A (en) * | 1992-07-07 | 1994-12-27 | Merck & Co., Inc. | High speed process for preparing orifices in pharmaceutical dosage forms |
CA2124568C (en) * | 1992-10-09 | 2003-11-11 | Yoshiaki Yano | Method for producing microgranulated particle |
DE69425453T2 (de) * | 1993-04-23 | 2001-04-12 | Novartis Ag | Wirkstoffabgabevorrichtung mit gesteuerter Freigabe |
US5457109A (en) * | 1993-09-15 | 1995-10-10 | Warner-Lambert Company | Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of disease states at risk for progressing to noninsulin-dependent diabetes mellitus |
DE4432757A1 (de) | 1994-09-14 | 1996-03-21 | Boehringer Mannheim Gmbh | Pharmazeutische Zubereitung enthaltend Metformin und Verfahren zu deren Herstellung |
US5917052A (en) | 1994-09-28 | 1999-06-29 | Shaman Pharmaceuticals, Inc. | Hypoglycemic agent from cryptolepis |
AUPM897594A0 (en) * | 1994-10-25 | 1994-11-17 | Daratech Pty Ltd | Controlled release container |
US5858398A (en) * | 1994-11-03 | 1999-01-12 | Isomed Inc. | Microparticular pharmaceutical compositions |
US5658474A (en) * | 1994-12-16 | 1997-08-19 | Alza Corporation | Method and apparatus for forming dispenser delivery ports |
TWI238064B (en) * | 1995-06-20 | 2005-08-21 | Takeda Chemical Industries Ltd | A pharmaceutical composition for prophylaxis and treatment of diabetes |
RU2158607C2 (ru) | 1995-07-03 | 2000-11-10 | Санкио Компани Лимитед | Лечение артериосклероза и ксантомы |
US5972389A (en) | 1996-09-19 | 1999-10-26 | Depomed, Inc. | Gastric-retentive, oral drug dosage forms for the controlled-release of sparingly soluble drugs and insoluble matter |
US5859037A (en) * | 1997-02-19 | 1999-01-12 | Warner-Lambert Company | Sulfonylurea-glitazone combinations for diabetes |
US6011049A (en) * | 1997-02-19 | 2000-01-04 | Warner-Lambert Company | Combinations for diabetes |
US6153632A (en) * | 1997-02-24 | 2000-11-28 | Rieveley; Robert B. | Method and composition for the treatment of diabetes |
US6291495B1 (en) * | 1997-02-24 | 2001-09-18 | Robert B. Rieveley | Method and composition for the treatment of diabetes |
JP4083818B2 (ja) | 1997-06-06 | 2008-04-30 | ディポメド,インコーポレイティド | 高度可溶性薬物の制御された放出のための胃滞留性の経口薬物投与形 |
US6056977A (en) * | 1997-10-15 | 2000-05-02 | Edward Mendell Co., Inc. | Once-a-day controlled release sulfonylurea formulation |
WO1999029314A1 (en) * | 1997-12-08 | 1999-06-17 | Bristol-Myers Squibb Company | Novel salts of metformin and method |
US5948440A (en) * | 1997-12-17 | 1999-09-07 | Ranbaxy Laboratories Limited | Modified release matrix formulation of cefaclor and cephalexin |
EA003101B1 (ru) * | 1998-03-19 | 2002-12-26 | Бристол-Майерз Сквибб Компани | Двухфазная система доставки с регулируемым высвобождением для фармацевтических средств с высокой растворимостью и способ лечения диабета с помощью этой системы |
US6099859A (en) * | 1998-03-20 | 2000-08-08 | Andrx Pharmaceuticals, Inc. | Controlled release oral tablet having a unitary core |
WO1999055320A1 (en) | 1998-04-29 | 1999-11-04 | Sumitomo Pharmaceuticals Co., Ltd. | Oral formulation comprising biguanide and an organic acid |
US6191162B1 (en) * | 1998-05-28 | 2001-02-20 | Medical Research Institute | Method of reducing serum glucose levels |
WO2000000195A1 (en) * | 1998-06-30 | 2000-01-06 | Takeda Chemical Industries, Ltd. | Pharmaceutical composition for the treatment of diabetes |
US6099862A (en) * | 1998-08-31 | 2000-08-08 | Andrx Corporation | Oral dosage form for the controlled release of a biguanide and sulfonylurea |
US20040081697A1 (en) * | 1998-11-12 | 2004-04-29 | Smithkline Beecham P.L.C. | Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent |
CZ20011629A3 (cs) | 1998-11-12 | 2001-12-12 | Smithkline Beecham Plc | Farmaceutický prostředek pro upravené uvolňování senzitizéru inzulínu a jiných antidiabetických přípravků |
US7374779B2 (en) * | 1999-02-26 | 2008-05-20 | Lipocine, Inc. | Pharmaceutical formulations and systems for improved absorption and multistage release of active agents |
US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
US6383471B1 (en) * | 1999-04-06 | 2002-05-07 | Lipocine, Inc. | Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents |
KR100752000B1 (ko) | 1999-05-27 | 2007-08-28 | 아쿠스피어 인코포레이티드. | 다공성 약물 매트릭스의 제조방법 |
AU1403501A (en) | 1999-11-16 | 2001-05-30 | Smithkline Beecham Plc | Novel composition and use |
AR030920A1 (es) | 1999-11-16 | 2003-09-03 | Smithkline Beecham Plc | Composiciones farmaceuticas para el tratamiento de la diabetes mellitus y condiciones asociadas con la diabetes mellitus, y procedimientos para preparar dichas composiciones |
CA2394968A1 (en) * | 1999-12-16 | 2001-06-21 | Alza Corporation | Dosage forms having a barrier layer to laser ablation |
BR0007360A (pt) | 1999-12-23 | 2001-08-14 | Johnson & Johnson | Composição de liberação controlada |
MXPA02006335A (es) | 1999-12-23 | 2002-12-13 | Pfizer Prod Inc | Forma de dosificacion de farmaco en capas impulsada por hidrogel. |
AR026148A1 (es) * | 2000-01-21 | 2003-01-29 | Osmotica Argentina S A | Dispositivo osmotico con pasaje preformado que aumenta de tamano |
SE0001151D0 (sv) | 2000-03-31 | 2000-03-31 | Amarin Dev Ab | Method for producing a controlled-release composition |
US6524621B2 (en) * | 2000-05-01 | 2003-02-25 | Aeropharm Technology Inc. | Core formulation |
US6296874B1 (en) * | 2000-05-01 | 2001-10-02 | Aeropharm Technology Incorporated | Core formulation comprising troglitazone and abiguanide |
US6780432B1 (en) | 2000-05-01 | 2004-08-24 | Aeropharm Technology, Inc. | Core formulation |
US6451342B2 (en) * | 2000-05-01 | 2002-09-17 | Aeropharm Technology Incorporated | Core formulation comprised of troglitazone and a biguanide |
US6403121B1 (en) * | 2000-05-01 | 2002-06-11 | Aeropharm Technology Incorporated | Core formulation |
DE10025946A1 (de) * | 2000-05-26 | 2001-11-29 | Gruenenthal Gmbh | Wirkstoffkombination |
US20030086972A1 (en) | 2000-08-09 | 2003-05-08 | Appel Leah E. | Hydrogel-driven drug dosage form |
WO2002028181A1 (en) | 2000-10-02 | 2002-04-11 | Usv Limited | Sustained release pharmaceutical compositions containing metformin and method of its production |
US6790459B1 (en) * | 2000-11-03 | 2004-09-14 | Andrx Labs, Llc | Methods for treating diabetes via administration of controlled release metformin |
US20060034922A1 (en) * | 2000-11-03 | 2006-02-16 | Andrx Labs, Llc | Controlled release metformin compositions |
US6866866B1 (en) * | 2000-11-03 | 2005-03-15 | Andrx Labs, Llc | Controlled release metformin compositions |
CA2436373A1 (en) * | 2001-01-30 | 2002-08-08 | Teijin Limited | Pharmaceutical composition |
JP4848558B2 (ja) | 2001-05-08 | 2011-12-28 | トーアエイヨー株式会社 | 塩酸メトホルミン含有速放性錠剤 |
US6838093B2 (en) * | 2001-06-01 | 2005-01-04 | Shire Laboratories, Inc. | System for osmotic delivery of pharmaceutically active agents |
WO2003004009A1 (en) | 2001-07-02 | 2003-01-16 | Geneva Pharmaceuticals, Inc. | Pharmaceutical composition |
US6703045B2 (en) * | 2001-08-21 | 2004-03-09 | Council Of Scientific & Industrial Research | Composition and method for maintaining blood glucose level |
AU2002341959A1 (en) * | 2001-10-04 | 2003-04-14 | Case Western Reserve University | Drug delivery devices and methods |
US20030091630A1 (en) | 2001-10-25 | 2003-05-15 | Jenny Louie-Helm | Formulation of an erodible, gastric retentive oral dosage form using in vitro disintegration test data |
US20030185882A1 (en) | 2001-11-06 | 2003-10-02 | Vergez Juan A. | Pharmaceutical compositions containing oxybutynin |
US8329217B2 (en) * | 2001-11-06 | 2012-12-11 | Osmotica Kereskedelmi Es Szolgaltato Kft | Dual controlled release dosage form |
ITFI20010230A1 (it) | 2001-11-29 | 2003-05-29 | Menarini Int Operations Lu Sa | Composizioni farmaceutiche per il trattamento del diabete mellito di tipo ii |
US20030118647A1 (en) * | 2001-12-04 | 2003-06-26 | Pawan Seth | Extended release tablet of metformin |
US20030224046A1 (en) * | 2002-06-03 | 2003-12-04 | Vinay Rao | Unit-dose combination composition for the simultaneous delivery of a short-acting and a long-acting oral hypoglycemic agent |
US8911781B2 (en) | 2002-06-17 | 2014-12-16 | Inventia Healthcare Private Limited | Process of manufacture of novel drug delivery system: multilayer tablet composition of thiazolidinedione and biguanides |
CN100367960C (zh) | 2002-07-11 | 2008-02-13 | 武田药品工业株式会社 | 包衣制剂的制备方法 |
US7785627B2 (en) * | 2002-09-20 | 2010-08-31 | Watson Pharmaceuticals, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
US7959946B2 (en) * | 2002-09-20 | 2011-06-14 | Watson Pharmaceuticals, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
EP1539144B1 (en) | 2002-09-20 | 2014-12-24 | Andrx Labs Llc | Multistage formulation containing a biguanide and a thiazolidinedione derivative |
IN192749B (es) | 2002-11-15 | 2004-05-15 | Ranbaxy Lab Ltd | |
KR101114808B1 (ko) * | 2003-01-29 | 2012-02-15 | 다케다 야쿠힌 고교 가부시키가이샤 | 피복 제제의 제조법 |
BRPI0417829A (pt) | 2003-12-19 | 2007-04-10 | Omega Bio Pharma Ip3 Ltd | composições e processos para tratamento da diabetes |
CN1968692A (zh) | 2004-05-03 | 2007-05-23 | 杜克大学 | 影响体重减轻的组合物 |
CN1327840C (zh) | 2004-06-08 | 2007-07-25 | 天津药物研究院 | 一种药物组合物及其在制备用于治疗糖尿病中的应用 |
-
2005
- 2005-03-30 US US11/093,742 patent/US9060941B2/en active Active
-
2006
- 2006-03-13 CA CA2601501A patent/CA2601501C/en not_active Expired - Fee Related
- 2006-03-13 JP JP2008504090A patent/JP5827781B2/ja not_active Expired - Fee Related
- 2006-03-13 UA UAA200712007A patent/UA91852C2/ru unknown
- 2006-03-13 GE GEAP200610344A patent/GEP20104936B/en unknown
- 2006-03-13 EA EA200702116A patent/EA015244B1/ru not_active IP Right Cessation
- 2006-03-13 EP EP06738170.7A patent/EP1863445B1/en active Active
- 2006-03-13 BR BRPI0609550-0A patent/BRPI0609550A2/pt not_active IP Right Cessation
- 2006-03-13 KR KR1020077021377A patent/KR101401412B1/ko not_active IP Right Cessation
- 2006-03-13 ES ES06738170.7T patent/ES2573321T3/es active Active
- 2006-03-13 AU AU2006232993A patent/AU2006232993B2/en not_active Ceased
- 2006-03-13 WO PCT/US2006/009082 patent/WO2006107528A1/en active Application Filing
- 2006-03-13 CN CN2006800097636A patent/CN101222912B/zh not_active Expired - Fee Related
- 2006-03-13 SG SG201001858-8A patent/SG160415A1/en unknown
- 2006-03-13 NZ NZ561124A patent/NZ561124A/en not_active IP Right Cessation
- 2006-03-13 MX MX2007011824A patent/MX2007011824A/es active IP Right Grant
- 2006-03-15 AR AR20060100990A patent/AR054238A1/es unknown
- 2006-03-22 TW TW095109953A patent/TWI344375B/zh not_active IP Right Cessation
- 2006-03-30 PE PE2006000354A patent/PE20061389A1/es not_active Application Discontinuation
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2007
- 2007-08-23 ZA ZA2007/07137A patent/ZA200707137B/en unknown
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- 2007-09-25 IL IL186308A patent/IL186308A/en not_active IP Right Cessation
- 2007-10-11 MA MA30295A patent/MA29675B1/fr unknown
- 2007-10-25 NO NO20075427A patent/NO20075427L/no not_active Application Discontinuation
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2008
- 2008-09-08 HK HK08109948.6A patent/HK1114337A1/xx not_active IP Right Cessation
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2013
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