AR061169A1 - Formulaciones farmaceuticas de fenilferina y composiciones para su absorcion en el colon - Google Patents
Formulaciones farmaceuticas de fenilferina y composiciones para su absorcion en el colonInfo
- Publication number
- AR061169A1 AR061169A1 ARP070102387A ARP070102387A AR061169A1 AR 061169 A1 AR061169 A1 AR 061169A1 AR P070102387 A ARP070102387 A AR P070102387A AR P070102387 A ARP070102387 A AR P070102387A AR 061169 A1 AR061169 A1 AR 061169A1
- Authority
- AR
- Argentina
- Prior art keywords
- phenylephrine
- colon
- erodible layer
- nucleus
- pharmaceutically acceptable
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pulmonology (AREA)
- Emergency Medicine (AREA)
- Virology (AREA)
- Immunology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Oncology (AREA)
- Ophthalmology & Optometry (AREA)
- Otolaryngology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente comunica una composicion farmacéutica que contiene fenilefrina o una sal de la misma aceptada farmacéuticamente y una capa erosionable la cual se utiliza para la administracion por vía oral, en donde la composicion distribuye la fenilefrina o una sal de la misma aceptada farmacéuticamente mediante la absorcion en el colon. La composicion farmacéutica contiene un nucleo con fenilefrina o una sal de la misma aceptada farmacéuticamente y una capa erosionable la cual depende del tiempo y del pH, o una capa erosionable que depende de la enzima específica del colon que se degrada para exponer el nucleo para liberar la fenilefrina en el colon. En una version aceptada, la capa erosionable encierra el nucleo. Opcionalmente la composicion además contiene fenilefrina en la capa erosionable u otra(s) capa(s) adicional(es). La composicion farmacéutica además puede contener uno o más agentes adicionales activos terapéuticamente seleccionados de uno o más grupos que consisten de antihistamínicos, analgésicos, un anti-piréticos y agentes anti-inflamatorios no-esteroidal. También da a conocer los métodos para administrar la fenilefrina por vía del colon, en consecuencia, aumentando la cantidad biodisponible de fenilefrina no-conjugada activa terapéuticamente en relacion con el total de fenilefrina en el plasma.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US81002106P | 2006-06-01 | 2006-06-01 | |
US87483006P | 2006-12-14 | 2006-12-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR061169A1 true AR061169A1 (es) | 2008-08-06 |
Family
ID=38659360
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP070102387A AR061169A1 (es) | 2006-06-01 | 2007-06-01 | Formulaciones farmaceuticas de fenilferina y composiciones para su absorcion en el colon |
Country Status (21)
Country | Link |
---|---|
US (2) | US8956662B2 (es) |
EP (2) | EP2366381A1 (es) |
JP (2) | JP5175278B2 (es) |
KR (1) | KR101643626B1 (es) |
CN (1) | CN104161736A (es) |
AR (1) | AR061169A1 (es) |
AU (1) | AU2007254821B2 (es) |
BR (1) | BRPI0712532A2 (es) |
CA (1) | CA2653953C (es) |
CL (1) | CL2007001584A1 (es) |
ES (1) | ES2391585T3 (es) |
HK (1) | HK1121970A1 (es) |
MX (1) | MX2008015360A (es) |
NO (1) | NO20085420L (es) |
NZ (1) | NZ573173A (es) |
PE (1) | PE20080151A1 (es) |
PL (1) | PL2034970T3 (es) |
RU (1) | RU2454225C2 (es) |
SG (1) | SG172664A1 (es) |
TW (1) | TWI411451B (es) |
WO (1) | WO2007143158A2 (es) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070253927A1 (en) * | 2006-04-13 | 2007-11-01 | Gwenaelle Jegou | Cosmetic compositions comprising at least one dielectrophile monomer and at least one radical initiator |
US8394415B2 (en) * | 2006-11-21 | 2013-03-12 | Mcneil-Ppc, Inc | Modified release analgesic suspensions |
US20080299186A1 (en) * | 2007-06-01 | 2008-12-04 | Schering-Plough Healthcare Products, Inc. | Coatings for applying substances onto substrate carrier |
US9833510B2 (en) * | 2007-06-12 | 2017-12-05 | Johnson & Johnson Consumer Inc. | Modified release solid or semi-solid dosage forms |
US8323695B2 (en) * | 2007-08-13 | 2012-12-04 | Mcneil-Ppc, Inc. | Method for stabilizing phenylephrine |
US20110150945A1 (en) * | 2008-08-11 | 2011-06-23 | Mepha Gmbh | Oral pharmaceutical formulation for omeprazole comprising a specific separation layer |
DE102008059206A1 (de) * | 2008-11-27 | 2010-06-10 | Bayer Schering Pharma Aktiengesellschaft | Pharmazeutische Darreichungsform enthaltend Nifedipin oder Nisoldipin und einen Angiotensin-II Antagonisten und/oder ein Diuretikum |
EP2210595A1 (en) | 2009-01-14 | 2010-07-28 | LEK Pharmaceuticals d.d. | Active coating of pharmaceutical dosage forms |
MX2009001925A (es) * | 2009-02-20 | 2010-08-20 | Senosiain S A De C V Lab | Composicion farmaceutica oral para uso en enfermedades respiratorias. |
AU2012316001A1 (en) * | 2011-09-27 | 2014-04-10 | Virginia Commonwealth University | Selective metabolic approach to increasing oral bioavailability of phenylephrine and other phenolic bioactives |
RU2540509C1 (ru) * | 2013-02-04 | 2015-02-10 | АФТ Фармасьютиклс Лтд | Лекарство |
ITMI20132066A1 (it) * | 2013-12-11 | 2015-06-12 | Farmatron Ltd | Sistemi terapeutici a rilascio modificato per la somministrazione orale di mentolo nel trattamento delle malattie intestinali |
ES2774359T3 (es) * | 2014-07-30 | 2020-07-20 | Merck Patent Gmbh | Composición que puede comprimirse directamente que contiene celulosa microcristalina |
JP6713450B2 (ja) | 2014-07-30 | 2020-06-24 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung | 活性化合物含有錠剤の製造用のプレミックス |
WO2016044704A1 (en) * | 2014-09-19 | 2016-03-24 | The Procter & Gamble Company | Pulsed release phenylephrine dosage forms |
GB201420306D0 (en) * | 2014-11-14 | 2014-12-31 | Bio Images Drug Delivery Ltd | Compositions |
ES2883352T3 (es) | 2016-03-25 | 2021-12-07 | Univ Gent | Forma de dosificación oral |
US10966928B2 (en) | 2016-03-25 | 2021-04-06 | Universiteit Gent | Oral dosage form |
JP2019513146A (ja) * | 2016-03-30 | 2019-05-23 | バイタル ビバレッジズ グローバル インコーポレーテッド | 選択的gi管送達のための組成物および方法 |
US10278930B2 (en) * | 2017-03-16 | 2019-05-07 | The Procter & Gamble Company | Method for relieving sinus congestion |
JP7218351B2 (ja) * | 2017-08-09 | 2023-02-06 | ヘルムホルツ-ツェントルン フュル インフェクティオンスフォルシュング ゲゼルシャフト ミット ベシュレンクテル ハフツング | 新たな標的化された細胞傷害性ラトジャドン誘導体及びそのコンジュゲート |
EP3622948A1 (en) | 2018-09-11 | 2020-03-18 | I.P.S. International Products & Services S.r.l. | Multilayered formulations with dual release rate of one or more active principles |
JP7263047B2 (ja) * | 2019-02-25 | 2023-04-24 | 沢井製薬株式会社 | フィルムコーティング錠剤 |
Family Cites Families (75)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3419565A (en) | 1963-04-24 | 1968-12-31 | Schering Corp | Aza-dibenzocycloheptenes |
NL132137C (es) | 1963-04-24 | |||
US3492397A (en) * | 1967-04-07 | 1970-01-27 | Warner Lambert Pharmaceutical | Sustained release dosage in the pellet form and process thereof |
US3558768A (en) * | 1969-12-19 | 1971-01-26 | Sterling Drug Inc | Sustained release pharmaceutical compositions |
US3559768A (en) * | 1969-12-22 | 1971-02-02 | Henry P Cox | Emergency elevator evacuation of tall buildings |
US3851051A (en) * | 1970-07-17 | 1974-11-26 | Scherer R Corp | Soft gelatin capsule containing high water content fill |
US3696188A (en) * | 1971-06-16 | 1972-10-03 | Schering Corp | Laminated tablets |
US3878217A (en) | 1972-01-28 | 1975-04-15 | Richardson Merrell Inc | Alpha-aryl-4-substituted piperidinoalkanol derivatives |
US4219559A (en) | 1979-01-10 | 1980-08-26 | Janssen Pharmaceutica N.V. | N-Heterocyclyl-4-piperidinamines |
US4291015A (en) * | 1979-08-14 | 1981-09-22 | Key Pharmaceuticals, Inc. | Polymeric diffusion matrix containing a vasodilator |
US4369184A (en) | 1980-01-24 | 1983-01-18 | Janssen Pharmaceutica N.V. | 1-(Cyclohexyl)-4-aryl-4-piperidinecarboxylic acid derivatives |
US4282233B1 (en) * | 1980-06-19 | 2000-09-05 | Schering Corp | Antihistaminic 11-(4-piperidylidene)-5h-benzoÄ5,6Ü-cyclohepta-Ä1,2Ü-pyridines |
FI75816C (fi) | 1981-02-06 | 1988-08-08 | Ucb Sa | Foerfarande foer framstaellning av terapeutiskt aktiv 2-/4-(difenylmetyl)-1-piperazinyl/-aettiksyror eller dess amid. |
US4389393A (en) | 1982-03-26 | 1983-06-21 | Forest Laboratories, Inc. | Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose |
HU194864B (en) * | 1984-02-15 | 1988-03-28 | Schering Corp | Process for production of 8-chlor-6,11-dihydro-11-(4-piperidilidene)-5h-benzo (5,6)-cyclo-hepta (1,2-b) pyridine and its salts |
US5025019A (en) * | 1984-04-09 | 1991-06-18 | Analgesic Associates | Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs |
DE3677842D1 (de) | 1985-05-13 | 1991-04-11 | Schering Corp | Verfahren zur herstellung von piperidyliden-dihydrodibenzo(a,d)zykloheptenen und deren azoderivate, so hergestellte verbindungen und ihre anwendung zur vorbereitung von heilmitteln. |
US4623664A (en) * | 1985-10-31 | 1986-11-18 | University Of Iowa Research Foundation | Oil suspended phenylephrine |
US4764378A (en) * | 1986-02-10 | 1988-08-16 | Zetachron, Inc. | Buccal drug dosage form |
US4816264A (en) * | 1986-06-06 | 1989-03-28 | Warner-Lambert Company | Sustained release formulations |
US4792452A (en) * | 1987-07-28 | 1988-12-20 | E. R. Squibb & Sons, Inc. | Controlled release formulation |
US5085865A (en) * | 1989-04-12 | 1992-02-04 | Warner-Lambert Company | Sustained release pharmaceutical preparations containing an analgesic and a decongestant |
US4990535A (en) | 1989-05-03 | 1991-02-05 | Schering Corporation | Pharmaceutical composition comprising loratadine, ibuprofen and pseudoephedrine |
US5133974A (en) * | 1989-05-05 | 1992-07-28 | Kv Pharmaceutical Company | Extended release pharmaceutical formulations |
FR2655266B1 (fr) * | 1989-12-05 | 1992-04-03 | Smith Kline French Lab | Compositions pharmaceutiques a base de cimetidine. |
ES2067957T3 (es) * | 1990-08-07 | 1995-04-01 | Pfizer | Uso de membranas polimerizadas interfacialmente en dispositivos de liberacion. |
US5518730A (en) * | 1992-06-03 | 1996-05-21 | Fuisz Technologies Ltd. | Biodegradable controlled release flash flow melt-spun delivery system |
ES2149250T3 (es) * | 1993-04-23 | 2000-11-01 | Novartis Ag | Dispositivo para la administracion de medicamentos con liberacion controlada. |
GB9402203D0 (en) | 1994-02-04 | 1994-03-30 | Smithkline Beecham Plc | Pharmaceutical formulation |
US5458879A (en) * | 1994-03-03 | 1995-10-17 | The Procter & Gamble Company | Oral vehicle compositions |
US5595997A (en) | 1994-12-30 | 1997-01-21 | Sepracor Inc. | Methods and compositions for treating allergic rhinitis and other disorders using descarboethoxyloratadine |
CN1235545A (zh) * | 1996-10-31 | 1999-11-17 | 先灵公司 | 含有氯雷他定和减充血剂的用于治疗哮喘的组合物 |
US6160020A (en) * | 1996-12-20 | 2000-12-12 | Mcneill-Ppc, Inc. | Alkali metal and alkaline-earth metal salts of acetaminophen |
MX9701946A (es) * | 1997-03-14 | 1998-04-30 | Arturo Jimenez Bayardo | Solucion oftalmica transportadora. |
US6210710B1 (en) * | 1997-04-28 | 2001-04-03 | Hercules Incorporated | Sustained release polymer blend for pharmaceutical applications |
DK1021204T3 (da) * | 1997-09-26 | 2006-05-08 | Noven Pharma | Bioadhæsive præparater og fremgangsmåder til topisk administration af aktive midler |
US6090411A (en) | 1998-03-09 | 2000-07-18 | Temple University | Monolithic tablet for controlled drug release |
US6602521B1 (en) * | 1998-09-29 | 2003-08-05 | Impax Pharmaceuticals, Inc. | Multiplex drug delivery system suitable for oral administration |
US6521254B2 (en) * | 1998-12-07 | 2003-02-18 | J-Med Pharmaceuticals, Inc. | Single-dose antihistamine/decongestant formulations for treating rhinitis |
ATE253354T1 (de) | 1999-02-23 | 2003-11-15 | Yuhan Corp | Kapseln mit loratadin und pseudoephedrin enthaltenden zusammensetzungen |
US6267986B1 (en) * | 1999-09-24 | 2001-07-31 | Ranbaxy Laboratories Limited | Process for the preparation of a controlled drug delivery system containing pseudoephedrine and a long acting antihistamine |
US6114346A (en) * | 1999-10-22 | 2000-09-05 | Schering Corporation | Treating sleep disorders using desloratadine |
SK287684B6 (sk) * | 1999-12-20 | 2011-06-06 | Schering Corporation | Pevná orálna farmaceutická dávková forma s predĺženým uvoľňovaním |
WO2001045676A2 (en) | 1999-12-20 | 2001-06-28 | Schering Corporation | Extended release oral dosage composition |
US6955821B2 (en) * | 2000-04-28 | 2005-10-18 | Adams Laboratories, Inc. | Sustained release formulations of guaifenesin and additional drug ingredients |
AU2001261744A1 (en) * | 2000-05-19 | 2001-12-03 | Npd Llc | Chewing gums, lozenges, candies, tablets, liquids, and sprays for efficient delivery of medications and dietary supplements |
AU2002220248A1 (en) * | 2000-11-06 | 2002-05-15 | Andrx Pharmaceuticals, Inc. | Once a day antihistamine and decongestant formulation |
US20030236275A1 (en) * | 2002-06-20 | 2003-12-25 | Schering Corporation | Treatment methods of nasal congestion and nasal obstruction |
US7163696B2 (en) | 2001-10-11 | 2007-01-16 | Pfizer Inc. | Pharmaceutical formulations |
US20030083354A1 (en) * | 2001-10-26 | 2003-05-01 | Pediamed Pharmaceuticals, Inc. | Phenylephrine tannate and pyrilamine tannate salts in pharmaceutical compositions |
US6827946B2 (en) * | 2001-12-05 | 2004-12-07 | Collegium Pharmaceutical, Inc. | Compositions containing both sedative and non-sedative antihistamines |
US20030114535A1 (en) * | 2001-12-14 | 2003-06-19 | Jame Fine Chemicals, Inc. | Dextrochlorpheniramine tannate |
AU2002242676B2 (en) | 2002-01-16 | 2008-05-29 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Bilayer pharmaceutical tablet comprising telmisartan and a diuretic and preparation thereof |
KR100540035B1 (ko) * | 2002-02-01 | 2005-12-29 | 주식회사 태평양 | 다단계 경구 약물 방출 제어 시스템 |
US20030175342A1 (en) * | 2002-03-14 | 2003-09-18 | Karl Kolter | Coated pharmaceutical single-unit delayed-release forms, based on polyvinyl acetate |
US20030203027A1 (en) * | 2002-04-26 | 2003-10-30 | Ethicon, Inc. | Coating technique for deposition of drug substance on a substrate |
RU2220740C1 (ru) | 2002-08-30 | 2004-01-10 | Гапонюк Петр Яковлевич | Средство для лечения аллергического ринита и аллергического конъюнктивита |
US20040253311A1 (en) | 2002-12-18 | 2004-12-16 | Roger Berlin | Multi-layer tablet comprising non-steroidal anti-inflammatory drugs, decongestants and non-sedating antihist amines |
US6979689B2 (en) * | 2002-12-20 | 2005-12-27 | Pediamed Pharmaceuticals, Inc. | Compositions and methods for treating upper respiratory congestion |
US20040214215A1 (en) * | 2003-03-07 | 2004-10-28 | Yu Ruey J. | Bioavailability and improved delivery of alkaline pharmaceutical drugs |
US20050152967A1 (en) * | 2003-03-28 | 2005-07-14 | Pfab, Lp | Dynamic variable release |
US20050026890A1 (en) * | 2003-07-31 | 2005-02-03 | Robinson Cynthia B. | Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with an antihistamine for treatment of asthma or chronic obstructive pulmonary disease |
US20050095288A1 (en) * | 2003-11-03 | 2005-05-05 | Andrx Labs, Llc | Decongestant and expectorant tablets |
US9492541B2 (en) * | 2004-09-14 | 2016-11-15 | Sovereign Pharmaceuticals, Llc | Phenylepherine containing dosage form |
US20050281875A1 (en) * | 2003-12-17 | 2005-12-22 | Sovereign Pharmaceuticals, Ltd. | Promethazine containing dosage form |
US20050266032A1 (en) * | 2003-12-17 | 2005-12-01 | Sovereign Pharmaceuticals, Ltd. | Dosage form containing multiple drugs |
US20050220877A1 (en) * | 2004-03-31 | 2005-10-06 | Patel Ashish A | Bilayer tablet comprising an antihistamine and a decongestant |
NZ555909A (en) * | 2004-12-13 | 2009-11-27 | Mcneil Ppc Inc | Compositions and methods for reducing the degradation of phenylephrine by oxygen |
US20060280795A1 (en) * | 2005-06-08 | 2006-12-14 | Dexcel Pharma Technologies, Ltd. | Specific time-delayed burst profile delivery system |
EP1942875B1 (en) | 2005-08-24 | 2015-08-12 | Rubicon Research Private Limited | Controlled release formulation |
US8940796B2 (en) * | 2006-02-21 | 2015-01-27 | Wyeth Llc | Phenylephrine liquid formulations |
US20080014274A1 (en) * | 2006-07-14 | 2008-01-17 | Wyeth | Enhanced stability phenylephrine liquid compositions |
US9005652B2 (en) * | 2006-07-25 | 2015-04-14 | Wyeth | Chewable tablet containing phenylephrine |
US8394415B2 (en) | 2006-11-21 | 2013-03-12 | Mcneil-Ppc, Inc | Modified release analgesic suspensions |
US7378082B1 (en) * | 2007-11-05 | 2008-05-27 | Inspire Pharmaceuticals, Inc. | Method for treating allergic rhinitis without adverse effects |
-
2007
- 2007-06-01 PL PL07777373T patent/PL2034970T3/pl unknown
- 2007-06-01 CL CL2007001584A patent/CL2007001584A1/es unknown
- 2007-06-01 AU AU2007254821A patent/AU2007254821B2/en active Active
- 2007-06-01 EP EP11158570A patent/EP2366381A1/en not_active Withdrawn
- 2007-06-01 NZ NZ573173A patent/NZ573173A/en unknown
- 2007-06-01 TW TW096119770A patent/TWI411451B/zh active
- 2007-06-01 SG SG2011039914A patent/SG172664A1/en unknown
- 2007-06-01 CA CA2653953A patent/CA2653953C/en active Active
- 2007-06-01 AR ARP070102387A patent/AR061169A1/es unknown
- 2007-06-01 CN CN201410407684.7A patent/CN104161736A/zh active Pending
- 2007-06-01 PE PE2007000684A patent/PE20080151A1/es active IP Right Grant
- 2007-06-01 US US11/756,881 patent/US8956662B2/en active Active
- 2007-06-01 KR KR1020087031284A patent/KR101643626B1/ko active IP Right Grant
- 2007-06-01 RU RU2008151949/15A patent/RU2454225C2/ru active
- 2007-06-01 JP JP2009513318A patent/JP5175278B2/ja active Active
- 2007-06-01 MX MX2008015360A patent/MX2008015360A/es active IP Right Grant
- 2007-06-01 WO PCT/US2007/013050 patent/WO2007143158A2/en active Application Filing
- 2007-06-01 EP EP07777373A patent/EP2034970B1/en active Active
- 2007-06-01 BR BRPI0712532-1A patent/BRPI0712532A2/pt not_active IP Right Cessation
- 2007-06-01 ES ES07777373T patent/ES2391585T3/es active Active
-
2008
- 2008-12-30 NO NO20085420A patent/NO20085420L/no not_active Application Discontinuation
-
2009
- 2009-03-23 HK HK09102755.2A patent/HK1121970A1/xx unknown
-
2012
- 2012-10-09 JP JP2012224253A patent/JP2013006878A/ja active Pending
-
2014
- 2014-12-16 US US14/571,890 patent/US20150290147A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP2034970A2 (en) | 2009-03-18 |
AU2007254821B2 (en) | 2013-11-14 |
CN104161736A (zh) | 2014-11-26 |
CA2653953C (en) | 2015-12-08 |
JP2009538920A (ja) | 2009-11-12 |
WO2007143158A3 (en) | 2008-11-27 |
TWI411451B (zh) | 2013-10-11 |
US8956662B2 (en) | 2015-02-17 |
SG172664A1 (en) | 2011-07-28 |
PE20080151A1 (es) | 2008-02-25 |
WO2007143158A2 (en) | 2007-12-13 |
US20150290147A1 (en) | 2015-10-15 |
BRPI0712532A2 (pt) | 2013-04-02 |
NO20085420L (no) | 2008-12-30 |
AU2007254821A1 (en) | 2007-12-13 |
NZ573173A (en) | 2012-03-30 |
ES2391585T3 (es) | 2012-11-28 |
EP2366381A1 (en) | 2011-09-21 |
JP2013006878A (ja) | 2013-01-10 |
TW200815050A (en) | 2008-04-01 |
US20080020055A1 (en) | 2008-01-24 |
PL2034970T3 (pl) | 2012-12-31 |
HK1121970A1 (en) | 2009-05-08 |
KR101643626B1 (ko) | 2016-07-29 |
RU2008151949A (ru) | 2010-07-20 |
JP5175278B2 (ja) | 2013-04-03 |
RU2454225C2 (ru) | 2012-06-27 |
KR20090014392A (ko) | 2009-02-10 |
CA2653953A1 (en) | 2007-12-13 |
CL2007001584A1 (es) | 2008-01-25 |
EP2034970B1 (en) | 2012-08-01 |
MX2008015360A (es) | 2009-03-06 |
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