EA200600925A1 - Производные триазола в качестве антагонистов вазопрессина - Google Patents

Производные триазола в качестве антагонистов вазопрессина

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Publication number
EA200600925A1
EA200600925A1 EA200600925A EA200600925A EA200600925A1 EA 200600925 A1 EA200600925 A1 EA 200600925A1 EA 200600925 A EA200600925 A EA 200600925A EA 200600925 A EA200600925 A EA 200600925A EA 200600925 A1 EA200600925 A1 EA 200600925A1
Authority
EA
Eurasian Patent Office
Prior art keywords
derivatives
vazopressin
triazole
antagonists
ring
Prior art date
Application number
EA200600925A
Other languages
English (en)
Other versions
EA010132B1 (ru
Inventor
Джастин Стивен Брайанс
Патрик Стивен Джонсон
Ли Ричард Робертс
Томас Рикманс
Original Assignee
Пфайзер Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0329693A external-priority patent/GB0329693D0/en
Priority claimed from GB0408789A external-priority patent/GB0408789D0/en
Application filed by Пфайзер Инк. filed Critical Пфайзер Инк.
Publication of EA200600925A1 publication Critical patent/EA200600925A1/ru
Publication of EA010132B1 publication Critical patent/EA010132B1/ru

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    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pulmonology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Pregnancy & Childbirth (AREA)
  • Nutrition Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Communicable Diseases (AREA)
  • Anesthesiology (AREA)
  • Oncology (AREA)

Abstract

Соединения формулы (I) или их фармацевтически приемлемые производные, где: V представляет собой прямую связь или -О-; кольцо А представляет собой возможно замещенное 5-7-членное насыщенное гетероциклическое кольцо или фениленовую группу.
EA200600925A 2003-12-22 2004-12-09 Производные триазола в качестве антагонистов вазопрессина EA010132B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0329693A GB0329693D0 (en) 2003-12-22 2003-12-22 Compounds useful in therapy
GB0408789A GB0408789D0 (en) 2004-04-20 2004-04-20 Triazole derivatives
PCT/IB2004/004059 WO2005063754A1 (en) 2003-12-22 2004-12-09 Triazole derivatives as vasopressin antagonists

Publications (2)

Publication Number Publication Date
EA200600925A1 true EA200600925A1 (ru) 2006-12-29
EA010132B1 EA010132B1 (ru) 2008-06-30

Family

ID=34740750

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200600925A EA010132B1 (ru) 2003-12-22 2004-12-09 Производные триазола в качестве антагонистов вазопрессина

Country Status (25)

Country Link
EP (1) EP1701959A1 (ru)
JP (1) JP4698604B2 (ru)
KR (1) KR100854872B1 (ru)
AP (1) AP2331A (ru)
AR (1) AR047340A1 (ru)
AU (1) AU2004309164B2 (ru)
BR (1) BRPI0417267A (ru)
CA (1) CA2551038C (ru)
CR (1) CR8481A (ru)
DO (1) DOP2004001062A (ru)
EA (1) EA010132B1 (ru)
EC (1) ECSP066647A (ru)
GE (1) GEP20084571B (ru)
HK (1) HK1095822A1 (ru)
IL (1) IL176349A (ru)
IS (1) IS8472A (ru)
MA (1) MA28393B1 (ru)
NL (1) NL1027833C2 (ru)
NO (1) NO20063380L (ru)
OA (1) OA13347A (ru)
PA (1) PA8620501A1 (ru)
PE (1) PE20051051A1 (ru)
TW (1) TWI287541B (ru)
UY (1) UY28693A1 (ru)
WO (1) WO2005063754A1 (ru)

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