EA199900787A1 - Производные никотинамида - Google Patents

Производные никотинамида

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Publication number
EA199900787A1
EA199900787A1 EA199900787A EA199900787A EA199900787A1 EA 199900787 A1 EA199900787 A1 EA 199900787A1 EA 199900787 A EA199900787 A EA 199900787A EA 199900787 A EA199900787 A EA 199900787A EA 199900787 A1 EA199900787 A1 EA 199900787A1
Authority
EA
Eurasian Patent Office
Prior art keywords
disorders
disease
allergic
rheumatoid
inflammatory
Prior art date
Application number
EA199900787A
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English (en)
Other versions
EA003528B1 (ru
Inventor
Энтони Марфэт
Роберт Джеймс Чеймберс
Джон Уэсли Уотсон
Джон Бин Ченг
Аллен Джейкоб Даплэнтьер
Эдуард Фокс Клайнмен
Original Assignee
Пфайзер Продактс Инк.
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Publication date
Application filed by Пфайзер Продактс Инк. filed Critical Пфайзер Продактс Инк.
Publication of EA199900787A1 publication Critical patent/EA199900787A1/ru
Publication of EA003528B1 publication Critical patent/EA003528B1/ru

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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
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  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Virology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
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  • Pain & Pain Management (AREA)
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  • Otolaryngology (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
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  • Hospice & Palliative Care (AREA)
  • Molecular Biology (AREA)
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  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

Соединение формулы (I), где m, n, o, p, q, r, A, B, D, E, R, R, R, R, R, R, Rи Rявляются такими, как определено в описании изобретения, применяемое при лечении респираторных, аллергических, ревматоидных расстройств, расстройств регуляции веса тела, воспалительных расстройств и расстройств центральной нервной системы, таких как астма, хроническое обструктивное заболевание легких, синдром респираторных заболеваний взрослых, шок, фиброз, легочная гиперчувствительность, аллергический ринит, атопический дерматит, псориаз, регулирование веса, ревматоидный артрит, кахексия, болезнь Крона, неспецифический язвенный колит, артритические состояния и другие воспалительные заболевания, депрессия, мультиинфарктная деменция и СПИД.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA199900787A 1997-04-04 1998-03-10 Производные никотинамида, их применение, фармацевтическая композиция, способ лечения и способ ингибирования изоферментов фдэ4 d EA003528B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4340397P 1997-04-04 1997-04-04
PCT/IB1998/000315 WO1998045268A1 (en) 1997-04-04 1998-03-10 Nicotinamide derivatives

Publications (2)

Publication Number Publication Date
EA199900787A1 true EA199900787A1 (ru) 2000-04-24
EA003528B1 EA003528B1 (ru) 2003-06-26

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EA199900787A EA003528B1 (ru) 1997-04-04 1998-03-10 Производные никотинамида, их применение, фармацевтическая композиция, способ лечения и способ ингибирования изоферментов фдэ4 d

Country Status (37)

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US (1) US6380218B1 (ru)
EP (1) EP0971894A1 (ru)
JP (2) JP2000510481A (ru)
KR (1) KR20010005954A (ru)
CN (1) CN1254335A (ru)
AP (1) AP1388A (ru)
AR (1) AR012574A1 (ru)
AU (1) AU738037B2 (ru)
BG (1) BG64356B1 (ru)
BR (1) BR9810733A (ru)
CA (1) CA2285548C (ru)
CO (1) CO4950625A1 (ru)
DZ (1) DZ2457A1 (ru)
EA (1) EA003528B1 (ru)
GT (1) GT199800058A (ru)
HN (1) HN1998000057A (ru)
HR (1) HRP980181B1 (ru)
HU (1) HUP0001243A3 (ru)
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KR20010005954A (ko) 2001-01-15
YU49899A (sh) 2002-09-19
JP2000510481A (ja) 2000-08-15
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EP0971894A1 (en) 2000-01-19
ID22781A (id) 1999-12-09
IL132033A0 (en) 2001-03-19
HN1998000057A (es) 1999-01-08
WO1998045268A1 (en) 1998-10-15
PL336148A1 (en) 2000-06-05
NZ337698A (en) 2001-07-27
NO994791L (no) 1999-12-01
JP2004083583A (ja) 2004-03-18
BG64356B1 (bg) 2004-11-30
BG103725A (en) 2000-07-31
BR9810733A (pt) 2000-09-12
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DZ2457A1 (fr) 2004-11-08
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CO4950625A1 (es) 2000-09-01
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AU738037B2 (en) 2001-09-06
UA67737C2 (ru) 2004-07-15
AP9801218A0 (en) 1998-06-30
AP1388A (en) 2005-04-14
HUP0001243A2 (hu) 2000-09-28
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CA2285548C (en) 2006-07-11
MA26479A1 (fr) 2004-12-20
NO314182B1 (no) 2003-02-10
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TR199902432T2 (xx) 2000-01-21
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PA8449601A1 (es) 2000-05-24
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OA11163A (en) 2003-04-28
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CA2285548A1 (en) 1998-10-15
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