EA199700201A1 - Парентеральные фармацевтические композиции, содержащие алкиламмониевые соли 2-арилпропиновых кислот - Google Patents

Парентеральные фармацевтические композиции, содержащие алкиламмониевые соли 2-арилпропиновых кислот

Info

Publication number
EA199700201A1
EA199700201A1 EA199700201A EA199700201A EA199700201A1 EA 199700201 A1 EA199700201 A1 EA 199700201A1 EA 199700201 A EA199700201 A EA 199700201A EA 199700201 A EA199700201 A EA 199700201A EA 199700201 A1 EA199700201 A1 EA 199700201A1
Authority
EA
Eurasian Patent Office
Prior art keywords
propinic
aryl
acids
pharmaceutical compositions
alkylammonium salts
Prior art date
Application number
EA199700201A
Other languages
English (en)
Other versions
EA000599B1 (ru
Inventor
Марко Джентиле
Луиджи Болтри
Гаэтано Клавенна
Original Assignee
ДОМПЕ' СпА
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ДОМПЕ' СпА filed Critical ДОМПЕ' СпА
Publication of EA199700201A1 publication Critical patent/EA199700201A1/ru
Publication of EA000599B1 publication Critical patent/EA000599B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Фармацевтическая композиция для парентерального введения, имеющая противовоспалительные и обезболивающие свойства, которая содержит в качестве активного начала алкиламмониевые соли 2-арилпропионовых кислот.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA199700201A 1995-12-28 1996-12-23 ПАРЕНТЕРАЛЬНАЯ ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, СОДЕРЖАЩАЯ СОЛЬ 2-АРИЛПРОПИОНОВОЙ КИСЛОТЫ С ОСНОВАНИЕМ, ВЫБРАННЫМ ИЗ α-АМИНОКИСЛОТЫ, ДРОПРОПИЗИНА И ТРОМЕТАМИНА EA000599B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT95MI002777A IT1277741B1 (it) 1995-12-28 1995-12-28 Composizioni farmaceutiche parenterali contenenti sali di alchilammonio di acidi 2-arilpropionici
PCT/IB1996/001461 WO1997024114A1 (en) 1995-12-28 1996-12-23 Parenteral pharmaceutical compositions containing ammoniumalkyl salts of 2-arylpropionic acids

Publications (2)

Publication Number Publication Date
EA199700201A1 true EA199700201A1 (ru) 1998-02-26
EA000599B1 EA000599B1 (ru) 1999-12-29

Family

ID=11372830

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199700201A EA000599B1 (ru) 1995-12-28 1996-12-23 ПАРЕНТЕРАЛЬНАЯ ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, СОДЕРЖАЩАЯ СОЛЬ 2-АРИЛПРОПИОНОВОЙ КИСЛОТЫ С ОСНОВАНИЕМ, ВЫБРАННЫМ ИЗ α-АМИНОКИСЛОТЫ, ДРОПРОПИЗИНА И ТРОМЕТАМИНА

Country Status (24)

Country Link
US (1) US5895789A (ru)
EP (1) EP0814797B1 (ru)
KR (1) KR19980702301A (ru)
CN (1) CN1082812C (ru)
AR (1) AR005308A1 (ru)
AT (1) ATE232096T1 (ru)
AU (1) AU1069897A (ru)
BR (1) BR9607422A (ru)
CA (1) CA2213232A1 (ru)
CZ (1) CZ290646B6 (ru)
DE (1) DE69626103T2 (ru)
DK (1) DK0814797T3 (ru)
EA (1) EA000599B1 (ru)
ES (1) ES2192234T3 (ru)
HK (1) HK1008777A1 (ru)
HU (1) HU224685B1 (ru)
IT (1) IT1277741B1 (ru)
NO (1) NO973921D0 (ru)
PL (1) PL187170B1 (ru)
PT (1) PT814797E (ru)
SI (1) SI9620023A (ru)
SK (1) SK282579B6 (ru)
TR (1) TR199700869T1 (ru)
WO (1) WO1997024114A1 (ru)

Families Citing this family (28)

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IT1298214B1 (it) * 1998-01-28 1999-12-20 Dompe Spa Sali dell'acido (r) 2-(3-benzoilfenil) propionico e loro composizioni farmaceutiche.
CA2406383A1 (en) * 2000-04-13 2001-10-25 Mayo Foundation For Medical Education And Research A.beta.42 lowering agents
US6342530B1 (en) 2000-11-14 2002-01-29 Farmacon-Il, Llc Composition and method for parenteral administration of ibuprofen d,l- or l-lysine salt
US6344479B1 (en) 2001-03-20 2002-02-05 Farmacon-Il, Llc Method of preventing retinopathy of prematurity in a neonate
US20040132823A1 (en) * 2001-11-02 2004-07-08 Leo Pavliv Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
ES2189682B1 (es) * 2001-12-11 2004-04-01 Laboratorios Del Dr. Esteve, S.A. Preparacion bebible que comprende ketoprofeno y su empleo en el tratamiento de procesos que cursan con fiebre, inflamacion y/o dolor, en un colectivo de animales, de forma simultanea.
AU2003274060A1 (en) * 2002-10-25 2004-05-13 Dompe S.P.A. Painless injectable compositions containing salt of 2-arylpropionic acids
US7090859B2 (en) * 2002-12-13 2006-08-15 Ronald Thomas Haas Ketoprofen compositions and methods of making them
EP1603548A4 (en) * 2003-02-05 2007-10-10 Myriad Genetics Inc COMPOSITION AND METHOD FOR TREATING NEURODEGENERATIVE DISORDERS
KR20060040676A (ko) * 2003-07-11 2006-05-10 미리어드 제네틱스, 인크. 알츠하이머병을 치료하기 위한 약제학적 방법, 투약 방법및 제형
WO2006001877A2 (en) * 2004-04-13 2006-01-05 Myriad Genetics, Inc. Combination treatment for neurodegenerative disorders comprising r-flurbiprofen
KR20070004036A (ko) * 2004-04-29 2007-01-05 키스톤 리테이닝 월 시스템스, 아이엔씨 벽, 옹벽 및 그 외 유사한 것을 위한 베니어
WO2006020850A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
BRPI0514303A (pt) * 2004-08-11 2008-06-10 Myriad Genetics Inc composição farmacêutica e método para tratar distúrbios neurodegenerativos
WO2006020852A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
AU2006239313A1 (en) * 2005-04-28 2006-11-02 Najib Babul Methods and compositions for treating pain
EA200800360A1 (ru) * 2005-07-22 2008-06-30 Мириад Дженетикс, Инк. Формуляции с высоким содержанием лекарства и дозированные формы
US20070265344A1 (en) * 2006-02-06 2007-11-15 Pharmaceutical Solutions, Inc. Non-steroidal anti-inflammatory oral powder and liquid preparations for administration to animals
RU2437657C2 (ru) * 2006-03-16 2011-12-27 Новартис Аг Твердая лекарственная форма, содержащая активный агент с маскированным вкусом
WO2008006099A2 (en) * 2006-07-07 2008-01-10 Myriad Genetics, Inc. Treatment of psychiatric disorders
FR2950533B1 (fr) * 2009-09-28 2012-01-13 Maco Pharma Sa Formulation liquide, stable, prete a l'emploi de ketoprofene
FR2971712B1 (fr) * 2011-02-22 2016-06-10 Map France Solution stable de ketoprofene pour injection intraveineuse
US8415337B1 (en) 2011-03-06 2013-04-09 Recordati Rare Diseases Inc. Ibuprofen compositions and methods of making same
CN102381986A (zh) * 2011-07-25 2012-03-21 南京特丰药业股份有限公司 一种右旋布洛芬氨丁三醇盐及其口服溶液的制备方法
CN103957886B (zh) * 2011-08-04 2016-03-30 奥默罗斯公司 稳定的抗炎注射溶液剂
CN102362857A (zh) * 2011-11-22 2012-02-29 陆荣政 一种右旋布洛芬注射液及其制备方法
GR1008942B (el) * 2015-10-14 2017-02-06 ΙΟΥΛΙΑ ΚΑΙ ΕΙΡΗΝΗ ΤΣΕΤΗ ΦΑΡΜΑΚΕΥΤΙΚΑ ΕΡΓΑΣΤΗΡΙΑ ΑΒΕΕ με δ.τ. "INTERMED ΑΒΕΕ" Μεθοδος παραγωγης σταθερου υδατικου διαλυματος λυσινικης ιμπουπροφαινης για ενδοκολπικη χρηση
WO2019105957A1 (en) 2017-11-30 2019-06-06 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. Stable liquid composition of ketoprofen, salts and enantiomers thereof

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GB1497044A (en) * 1974-03-07 1978-01-05 Prodotti Antibiotici Spa Salts of phenyl-alkanoic acids
DE2830921A1 (de) * 1978-07-14 1980-01-31 Bbc Brown Boveri & Cie Verfahren zum verhindern von sintererscheinungen an schmiedebloeckchen
HU185926B (en) * 1979-09-27 1985-04-28 Agostne Kahan Process for preparing water soluble derivatives of non-steroid antiinflammatory compositions and pharmaceutical compositins containing such derivatives
EP0070714B1 (en) * 1981-07-20 1986-05-07 The Upjohn Company Use of ibuprofen or flurbiprofen for the manufacture of a medicament for treating respiratory disorders
DE3328401A1 (de) * 1983-08-05 1985-02-21 Merckle GmbH, 7902 Blaubeuren Injizierbare loesung zur behandlung von entzuendungen
ATE50493T1 (de) * 1986-11-14 1990-03-15 Puetter Medice Chem Pharm Ibuprofen enthaltendes arzneimittel.
US4868214A (en) * 1987-11-17 1989-09-19 Analgesic Associates Onset-hastened/enhanced analgesia
US4887620A (en) * 1988-04-26 1989-12-19 Better Life International, Inc. Composition and method to provide organoleptic bite in a composition for human consumption
IT1255007B (it) * 1991-07-01 1995-10-11 Altergon Sa Sale solubile dell'ibuprofen c0n n-(2-idrossietil) pirrolidina e composizioni farmaceutiche che li contengono.
FR2687915B1 (fr) * 1992-02-28 1995-05-05 Rhone Poulenc Rorer Sa Composition pharmaceutique utilisable comme analgesique contenant l'acide (benzoyl-3 phenyl)-2 propionique-(r).
US5331000A (en) * 1992-03-09 1994-07-19 Sepracor Inc. Antipyretic and analgesic methods and compositions containing optically pure R(-) ketoprofen
WO1994020449A1 (en) * 1993-03-09 1994-09-15 Dompe'farmaceutici Spa Salts of 2-(3-benzoylphenyl)propionic acid with achiral and chiral organic bases and pharmaceutical compositions thereof

Also Published As

Publication number Publication date
NO973921L (no) 1997-08-26
IT1277741B1 (it) 1997-11-12
AR005308A1 (es) 1999-04-28
EP0814797A1 (en) 1998-01-07
SK282579B6 (sk) 2002-10-08
PL187170B1 (pl) 2004-05-31
ATE232096T1 (de) 2003-02-15
NO973921D0 (no) 1997-08-26
HK1008777A1 (en) 1999-07-16
SK113097A3 (en) 1998-02-04
TR199700869T1 (xx) 1997-12-21
ITMI952777A0 (ru) 1995-12-28
DE69626103T2 (de) 2003-12-04
MX9706237A (es) 1997-11-29
CA2213232A1 (en) 1997-07-10
CZ264397A3 (en) 1997-11-12
WO1997024114A1 (en) 1997-07-10
PT814797E (pt) 2003-06-30
DK0814797T3 (da) 2003-05-26
CZ290646B6 (cs) 2002-09-11
DE69626103D1 (de) 2003-03-13
HUP9801048A3 (en) 2000-07-28
ES2192234T3 (es) 2003-10-01
CN1176596A (zh) 1998-03-18
HUP9801048A1 (hu) 1998-10-28
CN1082812C (zh) 2002-04-17
HU224685B1 (hu) 2005-12-28
EA000599B1 (ru) 1999-12-29
EP0814797B1 (en) 2003-02-05
ITMI952777A1 (it) 1997-06-28
US5895789A (en) 1999-04-20
PL322165A1 (en) 1998-01-19
SI9620023A (sl) 1998-02-28
BR9607422A (pt) 1998-06-23
KR19980702301A (ko) 1998-07-15
AU1069897A (en) 1997-07-28

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Legal Events

Date Code Title Description
PD4A Registration of transfer of a eurasian patent in accordance with the succession in title
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU