ES8308854A1 - "un procedimiento para preparar esteres de acido antranilico". - Google Patents

"un procedimiento para preparar esteres de acido antranilico".

Info

Publication number
ES8308854A1
ES8308854A1 ES516059A ES516059A ES8308854A1 ES 8308854 A1 ES8308854 A1 ES 8308854A1 ES 516059 A ES516059 A ES 516059A ES 516059 A ES516059 A ES 516059A ES 8308854 A1 ES8308854 A1 ES 8308854A1
Authority
ES
Spain
Prior art keywords
anthranilic acid
acid esters
haloderivative
quinolyl
analgesic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES516059A
Other languages
English (en)
Other versions
ES516059A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Recordati SA
Original Assignee
Recordati SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati SA filed Critical Recordati SA
Publication of ES8308854A1 publication Critical patent/ES8308854A1/es
Publication of ES516059A0 publication Critical patent/ES516059A0/es
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE ESTERES DE ACIDO ANTRANILICO DE FORMULA (I) EN LA QUE N VALE 0-2; UNO DE R<1 Y R<2 ES CLORO O TRIFLUOROMETILO, Y EL OTRO ES HIDROGENO; Y R ES 2-OXO-3-OXOLANILO O 2-OXO-3-OXAZOLIDINILO. CONSISTE EN LA REACCION DE CONDENSACION DE UNA SAL DE UN ACIDO N-(7 U 8-SUSTITUIDO-4-QUINOLIL)-ANTRANILICO, DE FORMULA (II), CON UN DERIVADO HALOGENADO DE FORMULA HALO-(CH<2)<N-R, EN LAS QUE X ES UN METAL ALCALINO Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE ORGANICO, TAL COMO DIMETILFORMAMIDA A UNA TEMPERATURA ENTRE 30 C Y 150 C. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO ANALGESICOS Y ANTIINFLAMATORIOS.
ES516059A 1981-09-30 1982-09-29 "un procedimiento para preparar esteres de acido antranilico". Granted ES516059A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8129473 1981-09-30

Publications (2)

Publication Number Publication Date
ES8308854A1 true ES8308854A1 (es) 1983-10-01
ES516059A0 ES516059A0 (es) 1983-10-01

Family

ID=10524829

Family Applications (1)

Application Number Title Priority Date Filing Date
ES516059A Granted ES516059A0 (es) 1981-09-30 1982-09-29 "un procedimiento para preparar esteres de acido antranilico".

Country Status (21)

Country Link
US (1) US4507308A (es)
EP (1) EP0076600A1 (es)
JP (1) JPS5959664A (es)
AU (1) AU549754B2 (es)
CA (1) CA1193259A (es)
DE (1) DE3236096A1 (es)
DK (1) DK408782A (es)
ES (1) ES516059A0 (es)
FI (1) FI823294L (es)
GB (1) GB2106516B (es)
GR (1) GR77656B (es)
IL (1) IL66752A0 (es)
IT (1) IT1157325B (es)
NL (1) NL8203785A (es)
NO (1) NO823213L (es)
NZ (1) NZ201938A (es)
PT (1) PT75595B (es)
SE (1) SE8205523L (es)
SG (1) SG59485G (es)
YU (1) YU192782A (es)
ZA (1) ZA826291B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1193598A (en) * 1982-05-06 1985-09-17 Rafael Foguet 2-amino-benzoic acid derivatives and processes for their production
FR2873695A1 (fr) * 2004-07-30 2006-02-03 Palumed Sa Molecules hybrides qa ou q est une aminoquinoleine et a est un antibiotique ou un inhibiteur de resistance), leur synthese et leurs utilisations en tant qu'agent antibacterien
WO2006024741A2 (fr) * 2004-07-30 2006-03-09 Palumed S.A. Molecules hybrides qa ou q est une aminoquinoleine et a est un residu antibiotique, leur synthese et leurs utilisations en tant qu'agent antibacterien
FR2874922A1 (fr) * 2004-07-30 2006-03-10 Palumed Sa Molecules hybrides qa ou q est une aminoquinoleine et a est un residu antibiotique, leur synthese et leurs utilisations en tant qu'agent antibacterien
IT201600132467A1 (it) 2017-01-04 2018-07-04 H2Boat Turboespansore a strato limite e macchina a ciclo inverso provvista di tale turboespansore

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA731646A (en) * 1962-05-08 1966-04-05 Roussel-Uclaf 4-(2'(.beta.-MORPHOLYLETHOXYCARBONYL) PHENYLAMINE) 7-CHLORO QUINOLEINE ET SES SELS, AINSI QUE LEUR PROCEDE DE PREPARATION
FR6103M (es) * 1967-02-22 1968-06-10
FR6195M (es) * 1967-04-11 1968-07-22
FR7870M (es) * 1968-11-08 1970-04-27
US3637710A (en) * 1969-05-26 1972-01-25 Geigy Chem Corp 4-(phenylimino)-1 4-dihydroquinoline derivatives
US3764603A (en) * 1972-04-13 1973-10-09 Abbott Lab 2-hydroxy-2-carboxyethyl-n-(7- or 8-chloro-4-quinolinyl)anthranilate
GB1573186A (en) * 1977-09-14 1980-08-20 Wyeth John & Brother Ltd 4-aminoquinoline derivatives

Also Published As

Publication number Publication date
US4507308A (en) 1985-03-26
GB2106516B (en) 1985-03-27
IT1157325B (it) 1987-02-11
NZ201938A (en) 1985-04-30
SE8205523D0 (sv) 1982-09-28
CA1193259A (en) 1985-09-10
JPS5959664A (ja) 1984-04-05
FI823294L (fi) 1983-03-31
IL66752A0 (en) 1982-12-31
ES516059A0 (es) 1983-10-01
IT8223493A0 (it) 1982-09-29
DE3236096A1 (de) 1983-04-07
ZA826291B (en) 1983-07-27
GR77656B (es) 1984-09-25
DK408782A (da) 1983-03-31
YU192782A (en) 1985-04-30
NO823213L (no) 1983-04-05
PT75595B (fr) 1984-12-10
EP0076600A1 (en) 1983-04-13
PT75595A (fr) 1982-10-01
FI823294A0 (fi) 1982-09-24
SG59485G (en) 1986-08-01
SE8205523L (sv) 1983-03-31
AU549754B2 (en) 1986-02-13
AU8883982A (en) 1983-04-14
GB2106516A (en) 1983-04-13
NL8203785A (nl) 1983-04-18

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