ATE13286T1 - Pharmazeutisch aktive phenylcarbonsaeurederivate. - Google Patents
Pharmazeutisch aktive phenylcarbonsaeurederivate.Info
- Publication number
- ATE13286T1 ATE13286T1 AT82306930T AT82306930T ATE13286T1 AT E13286 T1 ATE13286 T1 AT E13286T1 AT 82306930 T AT82306930 T AT 82306930T AT 82306930 T AT82306930 T AT 82306930T AT E13286 T1 ATE13286 T1 AT E13286T1
- Authority
- AT
- Austria
- Prior art keywords
- acid derivatives
- pharmaceutically active
- compounds
- methods
- phenylic acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C205/59—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/41—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrogenolysis or reduction of carboxylic groups or functional derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
- C07C65/40—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups containing singly bound oxygen-containing groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8139027 | 1981-12-30 | ||
| EP82306930A EP0083228B1 (de) | 1981-12-30 | 1982-12-23 | Pharmazeutisch aktive Phenylcarbonsäurederivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE13286T1 true ATE13286T1 (de) | 1985-06-15 |
Family
ID=10526871
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT82306930T ATE13286T1 (de) | 1981-12-30 | 1982-12-23 | Pharmazeutisch aktive phenylcarbonsaeurederivate. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4499299A (de) |
| EP (1) | EP0083228B1 (de) |
| JP (1) | JPS58131936A (de) |
| AT (1) | ATE13286T1 (de) |
| AU (1) | AU9137082A (de) |
| CA (1) | CA1223601A (de) |
| DE (1) | DE3263573D1 (de) |
| DK (1) | DK578882A (de) |
| IE (1) | IE54269B1 (de) |
| NZ (1) | NZ202921A (de) |
| ZA (1) | ZA829046B (de) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5135940A (en) * | 1982-09-23 | 1992-08-04 | Merck Frosst Canada, Inc. | Leukotriene antagonists |
| GR78697B (de) * | 1982-10-21 | 1984-09-27 | Lilly Industries Ltd | |
| US4539419A (en) * | 1983-05-02 | 1985-09-03 | Hoffmann-La Roche Inc. | Naphthalenyloxy substituted carboxylic acids |
| US4764521A (en) * | 1983-07-18 | 1988-08-16 | Eli Lilly And Company | Leukotriene antagonists and a method of use there as |
| US5105017A (en) * | 1983-07-18 | 1992-04-14 | Eli Lilly And Company | Leukotriene antagonist intermediates |
| ES8602588A1 (es) * | 1983-10-27 | 1985-12-01 | Merck Frosst Canada Inc | Un procedimiento para la preparacion de nuevos antagonistas de los leucotrienos. |
| GB8333665D0 (en) * | 1983-12-16 | 1984-01-25 | Lilly Industries Ltd | Organic compounds |
| GB8524157D0 (en) * | 1984-10-19 | 1985-11-06 | Ici America Inc | Heterocyclic amides |
| US5179112A (en) * | 1985-04-17 | 1993-01-12 | Ici Americas Inc. | Heterocyclic amide derivatives and pharmaceutical use |
| GB8607294D0 (en) * | 1985-04-17 | 1986-04-30 | Ici America Inc | Heterocyclic amide derivatives |
| DE3515278A1 (de) * | 1985-04-27 | 1986-10-30 | Grünenthal GmbH, 5190 Stolberg | Neue benzoesaeurederivate, diese enthaltende arzneimittel und verfahren zur herstellung dieser verbindungen und arzneimittel |
| DE3518655A1 (de) * | 1985-05-24 | 1986-11-27 | Grünenthal GmbH, 5190 Stolberg | Neue phenolderivate, diese enthaltende arzneimittel und verfahren zur herstellung dieser verbindungen und arzneimittel |
| GB8623429D0 (en) * | 1985-10-17 | 1986-11-05 | Ici America Inc | Carboximide derivatives |
| IL80336A (en) * | 1985-10-17 | 1990-02-09 | Ici America Inc | Indole or benzopyrazole derivatives,their preparation and pharmaceutical compositions containing them |
| GB8609175D0 (en) * | 1986-04-15 | 1986-05-21 | Ici America Inc | Heterocyclic carboxamides |
| US5294613A (en) * | 1987-01-12 | 1994-03-15 | Eli Lilly And Company | Method of treating endotoxic shock in mammals |
| US4874777A (en) * | 1987-04-10 | 1989-10-17 | Eli Lilly And Company | Leukotriene antagonists |
| US4853398A (en) * | 1987-04-13 | 1989-08-01 | Eli Lilly And Company | Leukotriene antagonists and use thereas |
| EP0308977B1 (de) * | 1987-09-25 | 1993-12-08 | Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai | Anthracyclin-Derivate mit Inhibitorwirkung gegen die reverse Transkriptase des menschlichen Immundefizienzvirus |
| US5605930A (en) * | 1991-10-21 | 1997-02-25 | The United States Of America As Represented By The Department Of Health And Human Services | Compositions and methods for treating and preventing pathologies including cancer |
| PH30449A (en) * | 1991-11-25 | 1997-05-28 | Lilly Co Eli | Substituted phenyl phenol leukotriene antagonists |
| US6610329B2 (en) | 1993-04-22 | 2003-08-26 | Emisphere Technologies Inc. | Compositions for the delivery of antigens |
| US5457124A (en) * | 1993-12-07 | 1995-10-10 | Hoffmann-La Roche Inc. | Carboxylic acid Leukotriene B4 antagonists |
| US6790965B1 (en) | 1994-05-06 | 2004-09-14 | Pharmacopeia Drug Discovery, Inc. | Combinatorial dihydrobenzopyran library |
| US5688997A (en) * | 1994-05-06 | 1997-11-18 | Pharmacopeia, Inc. | Process for preparing intermediates for a combinatorial dihydrobenzopyran library |
| US6017768A (en) * | 1994-05-06 | 2000-01-25 | Pharmacopeia, Inc. | Combinatorial dihydrobenzopyran library |
| AU691296B2 (en) * | 1994-05-06 | 1998-05-14 | Pharmacopeia Drug Discovery, Inc. | Combinatorial dihydrobenzopyran library |
| US6001347A (en) | 1995-03-31 | 1999-12-14 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| DE19603329A1 (de) | 1996-01-31 | 1997-08-07 | Bayer Ag | Verfahren zur Herstellung von aromatischen Methoxycarbonsäuremethylestern |
| IL126318A (en) | 1996-03-29 | 2004-09-27 | Emisphere Tech Inc | Compounds and compositions for delivering active agents and some novel carrier compounds |
| US6358504B1 (en) | 1997-02-07 | 2002-03-19 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| CA2369591C (en) | 1999-04-05 | 2011-06-14 | Emisphere Technologies, Inc. | Disodium salts, monohydrate, and ethanol solvates |
| US7129274B1 (en) | 1999-11-05 | 2006-10-31 | Emisphere Technologies Inc. | Phenoxy carboxylic acid compounds and compositions for delivering active agents |
| AU2622301A (en) * | 1999-11-05 | 2001-05-14 | Emisphere Technologies, Inc. | Phenyl amine carboxylic acid compounds and compositions for delivering active agents |
| US7279597B1 (en) | 1999-11-05 | 2007-10-09 | Emisphere Technologies, Inc. | Phenyl amine carboxylic acid compounds and compositions for delivering active agents |
| US6693208B2 (en) | 1999-12-16 | 2004-02-17 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| US7238835B2 (en) * | 2003-12-22 | 2007-07-03 | Sanofi-Aventis Deutschland Gmbh | Process for the preparation of substituted 2-(phenoxymethyl) benzoic acids |
| DE102008008838A1 (de) | 2008-02-13 | 2009-08-20 | Bayer Healthcare Ag | Cycloalkoxy-substituierte 4-Phenyl-3,5-dicyanopyridine und ihre Verwendung |
| US8093253B2 (en) * | 2008-03-06 | 2012-01-10 | Hoffmann-La Roche Inc. | Leukotriene B4 inhibitors |
| WO2019120235A1 (zh) * | 2017-12-22 | 2019-06-27 | 中国科学院上海药物研究所 | 一类苯基羧酸衍生物、其制备方法及其用途 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3068213D1 (en) * | 1979-09-05 | 1984-07-19 | Glaxo Group Ltd | Phenol derivatives, processes for their preparation and pharmaceutical compositions containing them |
| GB2058785B (en) * | 1979-09-05 | 1983-05-25 | Glaxo Group Ltd | Phenol derivatives |
-
1982
- 1982-12-06 IE IE2885/82A patent/IE54269B1/en unknown
- 1982-12-06 US US06/447,467 patent/US4499299A/en not_active Expired - Fee Related
- 1982-12-08 ZA ZA829046A patent/ZA829046B/xx unknown
- 1982-12-09 AU AU91370/82A patent/AU9137082A/en not_active Abandoned
- 1982-12-14 CA CA000417658A patent/CA1223601A/en not_active Expired
- 1982-12-23 EP EP82306930A patent/EP0083228B1/de not_active Expired
- 1982-12-23 DE DE8282306930T patent/DE3263573D1/de not_active Expired
- 1982-12-23 NZ NZ202921A patent/NZ202921A/en unknown
- 1982-12-23 AT AT82306930T patent/ATE13286T1/de active
- 1982-12-24 JP JP57226484A patent/JPS58131936A/ja active Pending
- 1982-12-30 DK DK578882A patent/DK578882A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0083228B1 (de) | 1985-05-15 |
| DE3263573D1 (en) | 1985-06-20 |
| IE822885L (en) | 1983-06-30 |
| ZA829046B (en) | 1983-09-28 |
| IE54269B1 (en) | 1989-08-02 |
| CA1223601A (en) | 1987-06-30 |
| EP0083228A1 (de) | 1983-07-06 |
| US4499299A (en) | 1985-02-12 |
| DK578882A (da) | 1983-07-01 |
| NZ202921A (en) | 1986-03-14 |
| JPS58131936A (ja) | 1983-08-06 |
| AU9137082A (en) | 1983-07-07 |
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