ATE2427T1 - (dl)-16-phenoxy- und 16-substituierte phenoxy-9- keto prostatriensaeuren und derivate, verfahren zu deren herstellung und ihre pharmazeutischen zusammensetzungen. - Google Patents

(dl)-16-phenoxy- und 16-substituierte phenoxy-9- keto prostatriensaeuren und derivate, verfahren zu deren herstellung und ihre pharmazeutischen zusammensetzungen.

Info

Publication number
ATE2427T1
ATE2427T1 AT79102349T AT79102349T ATE2427T1 AT E2427 T1 ATE2427 T1 AT E2427T1 AT 79102349 T AT79102349 T AT 79102349T AT 79102349 T AT79102349 T AT 79102349T AT E2427 T1 ATE2427 T1 AT E2427T1
Authority
AT
Austria
Prior art keywords
phenoxy
keto
processes
derivatives
prostatric
Prior art date
Application number
AT79102349T
Other languages
English (en)
Inventor
Albert Van Horn
Gabriel Garay
John A. Dwards
Original Assignee
Syntex (U.S.A.) Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex (U.S.A.) Inc. filed Critical Syntex (U.S.A.) Inc.
Application granted granted Critical
Publication of ATE2427T1 publication Critical patent/ATE2427T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT79102349T 1978-07-10 1979-07-09 (dl)-16-phenoxy- und 16-substituierte phenoxy-9- keto prostatriensaeuren und derivate, verfahren zu deren herstellung und ihre pharmazeutischen zusammensetzungen. ATE2427T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/922,957 US4178457A (en) 1978-07-10 1978-07-10 (dl)-16-Phenoxy- and 16-substituted phenoxy-9-keto prostatrienoic acid derivatives and processes for the production thereof
EP79102349A EP0008003B1 (de) 1978-07-10 1979-07-09 (dl)-16-Phenoxy- und 16-substituierte Phenoxy-9-keto Prostatriensäuren und Derivate, Verfahren zu deren Herstellung und ihre pharmazeutischen Zusammensetzungen

Publications (1)

Publication Number Publication Date
ATE2427T1 true ATE2427T1 (de) 1983-03-15

Family

ID=25447871

Family Applications (1)

Application Number Title Priority Date Filing Date
AT79102349T ATE2427T1 (de) 1978-07-10 1979-07-09 (dl)-16-phenoxy- und 16-substituierte phenoxy-9- keto prostatriensaeuren und derivate, verfahren zu deren herstellung und ihre pharmazeutischen zusammensetzungen.

Country Status (26)

Country Link
US (1) US4178457A (de)
EP (1) EP0008003B1 (de)
JP (1) JPS5513282A (de)
KR (1) KR890002773B1 (de)
AT (1) ATE2427T1 (de)
AU (1) AU527516B2 (de)
CA (1) CA1149802A (de)
CS (1) CS209927B2 (de)
DD (1) DD146179A5 (de)
DE (2) DE2964709D1 (de)
DK (1) DK157753C (de)
ES (1) ES482330A1 (de)
FI (1) FI69061C (de)
FR (1) FR2430939A1 (de)
GB (1) GB2025413B (de)
HK (1) HK41384A (de)
HU (1) HU184185B (de)
IT (1) IT1121462B (de)
MY (1) MY8500576A (de)
NO (4) NO150836C (de)
NZ (1) NZ190924A (de)
PL (4) PL120632B1 (de)
SG (1) SG82483G (de)
SU (1) SU1031407A3 (de)
YU (3) YU41870B (de)
ZA (1) ZA793293B (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4328245A (en) * 1981-02-13 1982-05-04 Syntex (U.S.A.) Inc. Carbonate diester solutions of PGE-type compounds
US4358603A (en) * 1981-04-16 1982-11-09 Syntex (U.S.A.) Inc. Acetal stabilized prostaglandin compositions
US4409239A (en) * 1982-01-21 1983-10-11 Syntex (U.S.A.) Inc. Propylene glycol diester solutions of PGE-type compounds
US4804787A (en) * 1983-12-22 1989-02-14 Syntex (U.S.A.) Inc. Processes and intermediates for making 16-phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives
US4600785A (en) * 1983-12-22 1986-07-15 Syntex (U.S.A.) Inc. Processes and intermediates for making 16-phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives
US4912235A (en) * 1983-12-22 1990-03-27 Syntex (U.S.A.) Inc. Processes and intermediates for making 16-phenoxy- and 16-substituted phenoxy-prostatrienoic acid derivatives and their stereoisomers
DE3414509A1 (de) * 1984-04-13 1985-10-24 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 9-halogen-prostaglandine
US4792617A (en) * 1984-07-31 1988-12-20 Syntex (U.S.A.) Inc. 11-substituted-16-phenoxy and 16-substituted phenoxy-prostatrienioc acid derivatives
EP0170258B1 (de) * 1984-07-31 1989-12-27 Syntex (U.S.A.) Inc. 11-Substituierte-16-phenoxy und 16-phenoxysubstituierte Prostatriensäurederivate
US5057621A (en) * 1984-07-31 1991-10-15 Syntex (U.S.A.) Inc. 11-substituted-16-phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives
US4618696A (en) * 1984-07-31 1986-10-21 Syntex (U.S.A.) Inc. 9-oxo-15α-hydroxy-16-phenoxy and 16-substituted phenoxy 17,18,19,20-tetranorprosta-4,5,13,(E)-trienoates
US4778904A (en) * 1985-09-13 1988-10-18 Syntex (U.S.A.) Inc. Intermediates for making 16-phenoxy- and 16-(substituted phenoxy)-prostatrienoic acid derivatives
AU7139887A (en) * 1986-04-11 1987-10-15 Syntex (U.S.A.) Inc. Enprostil-type prostaglandins to regulate fat and carbohydrate metabolism
US4755531A (en) * 1986-08-11 1988-07-05 Syntex (U.S.A.) Inc. Thiol esters of 4,5-allenyl prostaglandins and use thereof as antigastric secretion agents
GB8625321D0 (en) * 1986-10-22 1986-11-26 Glaxo Group Ltd Chemical compounds
US4689419A (en) * 1986-11-14 1987-08-25 G. D. Searle & Co. Novel intermediate compounds in a process for producing 16-phenoxy- and 16-substituted phenoxy-9-keto-prostatrienoic acid derivatives
US6103765A (en) 1997-07-09 2000-08-15 Androsolutions, Inc. Methods for treating male erectile dysfunction
JP2001509480A (ja) 1997-07-09 2001-07-24 アンドロソリューションズ，インク． 男性勃起機能不全を治療するための改良された方法及び組成物
US20020037914A1 (en) 2000-03-31 2002-03-28 Delong Mitchell Anthony Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US8966971B2 (en) * 2008-07-28 2015-03-03 Ford Global Technologies, Llc Vehicle engine with fluid measuring system
US8623918B2 (en) 2008-10-29 2014-01-07 Novaer Holdings, Inc. Amino acid salts of prostaglandins
CA2739571A1 (en) * 2008-10-29 2010-08-26 Aerie Pharmaceuticals, Inc. Amino acid salts of prostaglandins
US8722739B2 (en) 2008-10-29 2014-05-13 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US20110293549A1 (en) 2009-02-03 2011-12-01 Athena Cosmetics, Inc. Composition, method and kit for enhancing hair

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES449162A1 (es) * 1975-06-23 1977-12-16 Syntex Inc Un procedimiento para la preparacion de un compuesto racemi-co u 8r-antimerico.

Also Published As

Publication number Publication date
FI69061C (fi) 1985-12-10
DK157753B (da) 1990-02-12
ES482330A1 (es) 1980-08-16
HK41384A (en) 1984-05-18
ZA793293B (en) 1981-02-25
FR2430939B1 (de) 1981-08-14
EP0008003A1 (de) 1980-02-20
PL121778B1 (en) 1982-05-31
DE2927715A1 (de) 1980-01-24
FI69061B (fi) 1985-08-30
US4178457A (en) 1979-12-11
NO150836C (no) 1985-01-09
NO152212C (no) 1985-08-21
AU527516B2 (en) 1983-03-10
NO840258L (no) 1980-01-11
SU1031407A3 (ru) 1983-07-23
FI792149A (fi) 1980-01-11
NO840257L (no) 1980-01-11
IT7968428A0 (it) 1979-07-09
SG82483G (en) 1984-08-03
CS209927B2 (en) 1981-12-31
DE2964709D1 (en) 1983-03-17
FR2430939A1 (fr) 1980-02-08
PL217001A1 (de) 1980-03-24
YU44553B (en) 1990-08-31
DK288879A (da) 1980-01-11
JPS5513282A (en) 1980-01-30
YU73586A (en) 1986-12-31
PL120632B1 (en) 1982-03-31
CA1149802A (en) 1983-07-12
NO150836B (no) 1984-09-17
GB2025413B (en) 1982-07-28
NO152211B (no) 1985-05-13
PL120633B1 (en) 1982-03-31
DE2927715C2 (de) 1987-08-27
EP0008003B1 (de) 1983-02-09
KR890002773B1 (ko) 1989-07-28
DK157753C (da) 1990-07-09
HU184185B (en) 1984-07-30
DD146179A5 (de) 1981-01-28
NO152211C (no) 1985-08-21
NZ190924A (en) 1980-11-28
MY8500576A (en) 1985-12-31
NO152296C (no) 1985-09-04
AU4864179A (en) 1980-02-07
GB2025413A (en) 1980-01-23
YU73686A (en) 1986-12-31
NO152212B (no) 1985-05-13
IT1121462B (it) 1986-04-02
NO792283L (no) 1980-01-11
NO152296B (no) 1985-05-28
YU41870B (en) 1988-02-29
YU44554B (en) 1990-08-31
NO840256L (no) 1980-01-11
PL120604B1 (en) 1982-03-31
YU168579A (en) 1983-02-28
JPS6210227B2 (de) 1987-03-05

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