EA199700095A1 - Фармацевтическая композиция для парентерального введения, содержащая индолкарбоновую кислоту - Google Patents

Фармацевтическая композиция для парентерального введения, содержащая индолкарбоновую кислоту

Info

Publication number
EA199700095A1
EA199700095A1 EA199700095A EA199700095A EA199700095A1 EA 199700095 A1 EA199700095 A1 EA 199700095A1 EA 199700095 A EA199700095 A EA 199700095A EA 199700095 A EA199700095 A EA 199700095A EA 199700095 A1 EA199700095 A1 EA 199700095A1
Authority
EA
Eurasian Patent Office
Prior art keywords
pharmaceutical composition
parenteral administration
carbonic acid
administration containing
indol
Prior art date
Application number
EA199700095A
Other languages
English (en)
Other versions
EA000211B1 (ru
Inventor
Андреа Лоди
Мария Тереза Россато
Original Assignee
ГЛАКСО ВЕЛЛКАМ С.п.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ГЛАКСО ВЕЛЛКАМ С.п.А. filed Critical ГЛАКСО ВЕЛЛКАМ С.п.А.
Publication of EA199700095A1 publication Critical patent/EA199700095A1/ru
Publication of EA000211B1 publication Critical patent/EA000211B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Пригодная для парентерального введения фармацевтическая композиция, содержащая раствор антагониста глицина, (Е)-3-[2-(фенилкарбамоил)этенил]-4,6-дихлориндол-2-карбоновой кислоты или ее физиологически приемлемой соли в изотоническом растворе сахара, содержащем смешиваемый с водой органический растворитель для указанного соединения, причем pH указанного препарата находится в пределах от 7 до 9.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA199700095A 1995-02-11 1996-02-08 Фармацевтические композиции для парентерального применения, содержащие индолкарбоновые кислоты EA000211B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9502695.1A GB9502695D0 (en) 1995-02-11 1995-02-11 Pharmaceutical composition
PCT/EP1996/000515 WO1996024376A1 (en) 1995-02-11 1996-02-08 Pharmaceutical composition for parenteral application containing an indole-carboxylic acid

Publications (2)

Publication Number Publication Date
EA199700095A1 true EA199700095A1 (ru) 1998-02-26
EA000211B1 EA000211B1 (ru) 1998-12-24

Family

ID=10769456

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199700095A EA000211B1 (ru) 1995-02-11 1996-02-08 Фармацевтические композиции для парентерального применения, содержащие индолкарбоновые кислоты

Country Status (18)

Country Link
US (2) US5886018A (ru)
EP (1) EP0809514A1 (ru)
JP (1) JPH10513464A (ru)
KR (1) KR19980702109A (ru)
AU (1) AU707220B2 (ru)
BR (1) BR9607433A (ru)
CA (1) CA2212041A1 (ru)
CZ (1) CZ252897A3 (ru)
EA (1) EA000211B1 (ru)
FI (1) FI973280A0 (ru)
GB (1) GB9502695D0 (ru)
HU (1) HUP9702448A2 (ru)
IL (1) IL117098A0 (ru)
NO (1) NO973656L (ru)
NZ (1) NZ300937A (ru)
PL (1) PL321734A1 (ru)
WO (1) WO1996024376A1 (ru)
ZA (1) ZA961051B (ru)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9502695D0 (en) * 1995-02-11 1995-03-29 Glaxo Spa Pharmaceutical composition
WO2003039540A2 (en) * 2001-11-09 2003-05-15 Sepracor Inc. D-amino acid oxidase inhibitors for learning and memory
US20040019075A1 (en) * 2002-05-29 2004-01-29 Boehringer Ingelheim Pharma Gmbh & Co. Kg New formulation for the parenteral application of crobenetine
CZ2006427A3 (cs) 2003-12-29 2006-11-15 Sepracor Inc. Pyrrolové a pyrazolové inhibitory DAAO
US8809393B2 (en) 2005-02-01 2014-08-19 Troikaa Pharmaceuticals Ltd Injectable preparations of diclofenac and its pharmaceutically acceptable salts
US7884124B2 (en) * 2006-06-30 2011-02-08 Sepracor Inc. Fluoro-substituted inhibitors of D-amino acid oxidase
US7579370B2 (en) * 2006-06-30 2009-08-25 Sepracor Inc. Fused heterocycles
US9737531B2 (en) 2012-07-12 2017-08-22 Glytech, Llc Composition and method for treatment of depression and psychosis in humans
AU2018284335A1 (en) 2017-06-12 2020-01-30 Glytech Llc. Treatment of depression with NMDA antagonists and D2/5HT2A or selective 5HT2A antagonists

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0347123A (ja) * 1989-05-05 1991-02-28 G D Searle & Co インドール―２―カルボキシレート化合物類を含有するｃｎｓ疾患治療用組成物
WO1992001670A1 (en) * 1990-07-16 1992-02-06 Merrell Dow Pharmaceuticals Inc. Excitatory amino acid antagonists
GB9208492D0 (en) * 1992-04-16 1992-06-03 Glaxo Spa Heterocyclic compounds
GB9502695D0 (en) * 1995-02-11 1995-03-29 Glaxo Spa Pharmaceutical composition

Also Published As

Publication number Publication date
PL321734A1 (en) 1997-12-22
NO973656L (no) 1997-10-08
CA2212041A1 (en) 1996-08-15
KR19980702109A (ko) 1998-07-15
IL117098A0 (en) 1996-06-18
JPH10513464A (ja) 1998-12-22
WO1996024376A1 (en) 1996-08-15
AU4622896A (en) 1996-08-27
HUP9702448A2 (hu) 1999-10-28
NO973656D0 (no) 1997-08-08
US5886018A (en) 1999-03-23
EP0809514A1 (en) 1997-12-03
AU707220B2 (en) 1999-07-08
BR9607433A (pt) 1998-05-26
FI973280A (fi) 1997-08-08
US6020359A (en) 2000-02-01
MX9706044A (es) 1998-06-28
NZ300937A (en) 1999-02-25
CZ252897A3 (cs) 1998-03-18
EA000211B1 (ru) 1998-12-24
ZA961051B (en) 1996-09-11
GB9502695D0 (en) 1995-03-29
FI973280A0 (fi) 1997-08-08

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AZ BY KZ KG TJ TM RU