EA031604B1 - Трепростинильные соединения, композиции и способы их использования - Google Patents

Трепростинильные соединения, композиции и способы их использования Download PDF

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Publication number
EA031604B1
EA031604B1 EA201690623A EA201690623A EA031604B1 EA 031604 B1 EA031604 B1 EA 031604B1 EA 201690623 A EA201690623 A EA 201690623A EA 201690623 A EA201690623 A EA 201690623A EA 031604 B1 EA031604 B1 EA 031604B1
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EA
Eurasian Patent Office
Prior art keywords
compound
patient
pharmaceutical composition
treprostinil
effective amount
Prior art date
Application number
EA201690623A
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English (en)
Russian (ru)
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EA201690623A1 (ru
Inventor
Владимир Малинин
Уолтер Перкинс
Франциска Лейфер
Донна Коничек
Чжили Ли
Адам Плонт
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Инсмед Инкорпорейтед
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Publication of EA201690623A1 publication Critical patent/EA201690623A1/ru
Publication of EA031604B1 publication Critical patent/EA031604B1/ru

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    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
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    • C07C69/734—Ethers
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    • C07C69/74—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C69/753—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring of polycyclic acids
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    • A61M2202/00—Special media to be introduced, removed or treated
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    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
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